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알코올 금단 증상의 치료에서 Topiramate의 효과 및 안정성
최은애,기선완,김성은,김지웅,박진균 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3
Objectives : Benzodiazepines are most often used for the treatment of alcohol withdrawal, but they also may result in several adverse consequencies such as sedation, respiratory depression, cognitive impairment, disinhibition, and abuse. New anticonvulsants, topiramate may have a potential to treat alcohol withdrawal effectively. This study compared the therapeutic responses of a benzodiazepine, lorazepam, and an anticonvulsant, topiramate, for the treatment of alcohol withdrawal. Methods : Fifty-two hospitalized patients with the diagnosis of DSM-IV Alcohol dependence, after obtaining written informed consent, were randomely divided into the either lorazepam (N=27) or the topiramate (N=25) groups. Subjects were assessed with CIWA-Ar scores at the time of baseline, 1, 3, 5 day after the last alcohol drinking. Lorazepam was given 4 mg divided by 4 on day 1, tapering to 2 mg divided by 2, and topiramate was given fixed single dose of 50 mg a day. Results : There were no significant differences between two groups in demographic or clinical characteristics except marital status and s-ALT level. Two groups had similar ADS scores and baseline withdrawal severity. There were no significant differences by treatment group in CIWA-Ar scores over time (F=0.883, P>0.05). Conclusion : Efficacy and safety were not different between the two groups. Therefore our results suggest that topiramate is a Promising alternative agent to benzodiazepine for treating alcohol withdrawal.
그림책에 대한 교사의 질문유형이 유아의 언어표현력 및 사고력에 미치는 영향
최은애,박혜경 동덕여자대학교 2003 생활과학연구 Vol.8 No.-
The purpose of this study is to testify whether divergent questions among the questioning types influence on language expression and thinking ability of young children. The subjects of study were 40 five-year-old children in Y kindergarten located in Nowon-gu, Seoul. Two groups, each of 20 children, were chosen from 40 children. One group were asked of divergent type questions as the experimental group, and the other group were asked of convergent type as the comparative group. The experiment had, been conducted as much 10 times main tests in total, twice per week. As a results, statistically, there were no meaningful difference of young children`s language expression ability and thinking ability between the experimental group and the comparative group. However, in the interaction between the teacher and the children, we could find that the children in the experimental group gradually increased the number of new words and sentences, adding a new word, and showed diverse and abundant expression in the content. They expressed divergent way of thinking and used reasoning power about a given situation improved.
최은애,송준임 한국동물분류학회 2016 Animal Systematics, Evolution and Diversity Vol.32 No.1
Dendrophyllia compressa Ogawa and Takahashi, 1995 is newly reported from Korea. The specimen was collected off Seogwipo, Jeju-do, Korea in 1969. It is described herein based on the morphological characters of the skeletal structures. Dendrophyllia compressa is characterized by its small and bushy growth form with branches, vertical growth direction, small calicular diameter, compressed calice, Pourtalès Plan with vertical septal inner edges, flat and spongy columella, exserted septal upper margins, and epitheca. Dendrophyllia compressa has been synonymized with Cladopsammia eguchii (Wells, 1982). However, the former species differs from the latter species in its growth form, growth direction, colony size, corallite size, and corallite shape.
카지노 딜러가 인식하는 감정노동이 리더의 감성지능의 수준에 의한 고객 지향성에 미치는 영향에 관한 연구
최은애 한국관광산업학회 2011 Tourism Research Vol.32 No.-
This study aimed at inquiring into the effect of the emotional labor of casino dealers' perception on customer orientation, and catching the moderating role by the level of leader's emotional intelligence as the mechanism, which can ease this relation. A survey was made on casino dealers at Kangwon Land through questionnaires. The factors composition, which releases in the existing precedent studies, was almost supported by measuring the emotional labor and customer orientation with casino dealers on the basis of the existing precedent studies. The well-timed application of the emotional application, emotional regulation and emotional perception of leader for efficient organization management in casino corporations could contribute to efforts for the inspiration and raise of dealers' customer-oriented mind.
최은애,송준임 한국동물분류학회 2015 Animal Systematics, Evolution and Diversity Vol.31 No.2
The two zooxanthellate scleractinian corals are newly recorded in Korea: Psammocora albopicta Benzoni, 2006 of the family Psammocoridae and Oulastrea crispata (Lamarck, 1816) of the family Faviidae. These families are also newly recorded in Korea. Specimens were collected from the subtidal zones of Jeju-do Island, Korea by SCUBA diving from 1999 to 2014. Two scleractinians are described based on the morphological characters of skeletal structures. Psammocora albopicta is distinguished by its encrusting cerioid growth form, high density of corallites, small calicular diameter, single styliform columella, and fewer rows of enclosed septa. Oulastrea crispata is characterized by its encrusting plocoid growth form, polygonal calicular shape, irregular paliform lobes, and papillose columella.
탄소 빔 분할조사 시 Linear-Quadratic모델, Incomplete-Repair모델, Marchese 모델 결과 비교
최은애 한국방사선학회 2015 한국방사선학회 논문지 Vol.9 No.6
We obtained Surviving Fraction (SF) after irradiation carbon beam to compare the applicability of the Linear-Quadratic model, Incomplete Repair model, Marchese model. Mathematica software(ver 9.0) used to calcurate parameters and compared result. LQ model could not explain the entire response of fractionated carbon beam irradiation. It becomes necessary to construct models that extend the LQ model of conventional radiotherapy for the carbon beam therapy. By combining both Potentially Lethal Damage Repair (PLDR) and Sublethal Damage Repair (SLDR) a new LQ model can develop that aptly modeled the cellular response to fractionated irradiation. 본 연구는 탄소 빔의 분할조사 후 세포생존율 (Surviving Fraction, SF) 값에 따른 Linear-Quadratic model, Incomplete Repair model, Marchese model의 결과값을 비교하기 위해 진행하였다. 탄소 빔을 4fraction까지 조사한 후 얻은 세포생존율 값을 바탕으로 mathematica 프로그램 (ver 9.0)을 이용하여 각각의 모델로 결과값을 얻어 비교 해 보았다. 그 결과 즉시 NB1RGB를 시딩한 값은 repair가 감안되지 않은 LQ 모델이 적합하였지만 fraction 시행한 후의 결과값은 오차를 보였다. 따라서 Potentially Lethal Damage Repair (PLDR)과 Sublethal Damage Repair (SLDR)의 발생을 각각 감안한 repair 모델을 이용하여 적합한지 판단하였다. 이를 바탕으로 탄소 빔의 분할 조사 시 LQ 모델에 각각의 repair의 양을 감안한 새로운 회복 관련 모델의 적용 가능성을 보고자 하였다.