한국보건간호학회 : 군보건소의 건강증진사업의 실제

최윤진 대한보건협회 1998 대한보건협회 보건종합학술대회 Vol.- No.-

일반인과 스포츠 선수의 보행 운동 모듈 분석

최윤진,최유림,김민희,윤범철 대한스포츠물리치료학회 2016 정형스포츠물리치료학회지 Vol.12 No.2

The motor module is regarded as the strategy by which the central nervous system (CNS) simplifies various complex movements. It consists of two components:muscle synergy vectors (the relative weighting of muscles within each motor module) and synergy activation coefficient (the relative activation of the motor modules). This study investigated the structures of motor modules in athletes during gait. Eight elite hockey players and six non-athletes performed 10 trials of gait. Activity levels of sixteen lower limb and trunk muscles were recorded with electromyography and motor modules were extracted using non-negative matrix factorization. The least number of motor modules that can explain more than 90% (total variability accounted for; VAF total) of the original data were selected. Three statistical analyses were used to compare structures of motor modules in athletes and non-athletes: an independent t-test to record the number of motor modules, one-way analysis of variance to study muscle synergy vectors, and correlation analysis to determine synergy activation coefficients. Four motor modules were extracted from both athletes and non-athletes. Three motor modules were similar between the two groups (r>0.625) while one module was significantly different in the adductor muscles. Our study identified common motor modules between athletes and non-athletes during gait but also identified a specific motor module in athletes that demonstrated a high contribution of tensor fasciae latae.

[92-1] 청소년심리학

최윤진 한국청소년정책연구원 1990 지도자교재지침서 Vol.- No.-

학생청소년 권리의 내용과 그 제한 근거에 관한 고찰

최윤진 한국청소년개발원 1992 청소년연구정보자료 Vol.- No.2

[93-05] 청소년 가정지도의 실태와 지도방안에 관한 연구 -가정지도편람(Ⅱ)개발을 위한 기초조사 연구-

최윤진 한국청소년정책연구원 1993 한국청소년정책연구원 연구보고서 Vol.- No.-

KC-100 항공기 연료계통 엔진공급 성능해석 및 시험결과 비교

최윤진,김덕열,천태욱,이상준,이강이 한국항공우주학회 2012 한국항공우주학회 학술발표회 논문집 Vol.2012 No.11

KC-100 연료계통의 성능은 연료계통 지상시험 및 엔진 기체 적합성 시험 등을 통해 검증 받고 비행안정성을 획득하게 된다. 최적의 연료계통 형상을 도출하기 위해서는 연료계통의 구성품 및 배관에 대한 해석 결과가 설계에 반영되어야 한다. KC-100 연료계통의 성능해석 중 엔진공급 성능해석은 엔진에서 요구되는 조건에 대한 성능 만족 여부를 판단하기 위해 수행되며 매우 주요한 해석 항목이다. KC-100 연료계통의 엔진공급 성능해석은 플로우마스터 (Flowmaster) 를 활용하여 수행되었으며, 성능해석 결과를 연료계통 지상시험의 결과와 비교함으로써 성능해석의 신뢰도를 확인하였다. 시험 결과는 KC-100 시제 1 호기에 대하여 실시된 엔진 기체 적합성 지상시험 결과를 기준으로 하였다. The fuel system performance of KC-100 aircraft is verified through fuel system ground test and engine aircraft compatibility test then acquire the safety of flight. For design optimization of the fuel system, the analysis result for fuel system components and routings must be reflected to system design. The engine feed performance analysis is performed to determine if the system performance meets the interface requirement from engine, so this is important analysis of the various performance analyses done for KC-100 fuel system. Flowmaster program was utilized for engine feed performance analysis and the analysis result was compared with the test result the reliability of the analysis method was verified. The test result was from the engine aircraft compatibility ground test performed on KC-100 AA-01 aircraft.

Expression of Leucine-rich Repeat-containing G-protein Coupled Receptor 5 and CD44: Potential Implications for Gastric Cancer Stem Cell Marker

최윤진,김나영,이혜승,박선미,박지현,윤혁,신철민,박영수,김진욱,이동호 대한암예방학회 2016 Journal of cancer prevention Vol.21 No.4

Background: The human leucine-rich repeat-containing G-protein coupled receptor (LGR) 5 and CD44 are one of the candidates for the marker of gastric cancer stem cells. We compared the expressions of two genes among control, dysplasia and cancer groups. Methods: We compared the mRNA expression of LGR5, CD44 and CD44v8-10 and immunohistochemistry (IHC) of LGR5 and CD44 in gastric antral mucosa of 45 controls, 36 patient with gastric dysplasia, and 39 patients with early gastric cancer. Additionally, IHC of LGR5 in gastric body mucosa was analyzed. Normal mucosa adjacent to dysplastic or cancer lesions was used for the quantitative real-time–PCR and IHC. Results: Immunoreactivity of LGR5 in base of antral mucosa was higher in non-cancerous tissues of cancer than those of control (P =0.006), whereas the expression of LGR5 mRNA was not different among the three groups. Immunostaining of LGR5 was much stronger in the antrum than in the body of stomach (P < 0.001). Although there was no difference in antral immunointensity of LGR5 according to the severity of intestinal metaplasia, stronger immunostaining was found in the body with an aggravation of intestinal metaplasia (P trend < 0.001). The expression of CD44v8-10 mRNA was higher in cancer patients than control subjects and patients with dysplasia (P = 0.018 and 0.009) while the expression of CD44 mRNA was higher in the control groups than the others. Conclusions: IHC of LGR5 in crypt base and CD44 may be used for gastric CSC markers. LGR5 expression may be associated with the developing of corporal intestinal metaplasia. The expression of CD44v8-10 mRNA would be more suitable for gastric cancer stem cell marker than CD44 or LGR5 mRNA.

새로운 칼륨 경쟁적 위산분비 차단제

최윤진 대한소화기학회 2022 대한소화기학회지 Vol.80 No.6

Proton pump inhibitors (PPIs) have several limitations to their efficacy including insufficient acid suppression, slow onset of action, and variable efficacy among patients due to CYP2C19 metabolism. Potassium-competitive acid blockers inhibit H+-K+-ATPase in a reversible and K+-competitive manner, are novel acid suppressive drugs with rapid onset of action, meal independence, and prolonged control of intragastric acidity compared to PPIs. Potassium-competitive acid blockers exhibited non-inferior therapeutic efficacies on reflux esophagitis, gastric ulcers, and Helicobacter pylori eradication. The review is focused on the unmet needs across the acid-related diseases and recent updates on clinical studies using vonoprazan and tegoprazan.

[94-02] 소년교정기관에서의 상과 벌 -비행청소년 교정프로그램의 실태와 개선방안 연구-

최윤진 한국청소년정책연구원 1994 한국청소년정책연구원 연구보고서 Vol.- No.-

노인주거복지시설의 운영에 따른 공간구성에 관한 연구

최윤진 대한산업경영학회 2019 산업융합연구 Vol.17 No.1

2000년 고령화 사회에 진입한 우리나라는 17년이 지난 2017년말에 예상보다 빠르게 고령사회로 진입하게 되 었다. 이러한 추세에 비하여 아직 노인주거시설에 관한 인식은 사회에 정착하지 못하고 있으며, 다양한 이유 중 가장 큰 이유는 시설의 건축과 경영에 대한 이해가 부족하여 노인주거시설의 활성화가 이루어지지 못한 것이라 할 수 있다. 더불어 정부의 정책 또한 뒷받침을 하지 못하는 면도 무시할 수 없다. 노인의 주거는 단순한 주거 공간 뿐 만이 아니라 의료의 문제와 연관지어서 생각해야 한다는 점과 지속적인 케어의 문제를 함께 고려해야 한다. 그래서 노인주거의 추세 는 연속보호형 시설(Continuing Care Retirement Commuity)을 추구하고 있다고 할 수 있다. 이에 본 연구는 기존의 노 인주거시설의 정책과 기존 노인주거를 외국의 정책 및 주거와의 비교를 통하여 분석한다. 이 결과를 바탕으로 노인주거 시설의 운영을 중심으로 경제적 부담을 최소화하기 위해 기본UNIT의 유지, 시설의 용도변경을 통한 융툥성의 확보, 공 용공간의 쉐어, 운영비의 현실화 등을 통해 노인주거시설의 적합한 주거디자인의 유형의 특성과 방향성을 제시하고 증 가하는 노인인구에 대처할 수 있는 사회복지적 방안을 연구함에 의의를 두고자 한다. Korea, which became an aging society in 2000, has made transition to an aged society more quickly than expected since late 2017 after 17 years. Despite this trend, the awareness towards elderly housing facilities has not yet been raised across in society. The primary reason is that use of elderly housing facilities has not been promoted due to lack of understanding about the construction and management of the facilities. The housing of the elderly should be considered in terms of not only residential space but also the issues of medical care and continuous care. Therefore, the trend of elderly housing is pursuing the Continuing Care Retirement Community. Thus, this study analyzed the policies of existing elderly housing facilities and existing elderly housing through comparison with policies and housing of foreign countries. Based on the results, the the government intends to present characteristics and direction of suitable housing design of senior citizens' housing facilities through maintenance of UNIT, securing convergence through changes in the use of facilities, and realising the cost of operation, and studying social welfare measures to cope with the increasing number of elderly residents.