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최보경(Bo Kyoung Choi),현태선(Tai Sun Hyun) 충북대학교 생활과학연구소 2012 생활과학연구논총 Vol.16 No.2
The purpose of this study was to investigate dietary habits and nutrient intake of college students through 'idiet' website and evaluate satisfaction of the website. The subjects were 166 students who registered 'food and nutrition' as a general education course in Chungbuk National University. Dietary habits, dietary attitudes, food frequency, and dietary intake were investigated through the 'idiet' website by himself/herself. More than two thirds(69.3%) of the subjects were categorized as 'poor' in dietary habits, and 36.7% were categorized as 'poor' in dietary attitudes. Nutrient intakes were estimated on the website when the students chose the name and the amount of the foods they ate during 24 hours with the help of real-size photos provided on the website. Mean daily energy intakes were 2,146 kcal, and 1,667 kcal in male and female students, respectively, which were comparable with those published in the previous studies estimated though a 24-hour recall or a food record method. Mean daily intakes of vitamin C, riboflavin and calcium were less than 75% of Recommended Intakes. Nutrient intakes of the subjects who were categorized as 'good' in dietary habits and food frequency were significantly higher than those who were categorized as 'poor'. The usefulness of the contents were evaluated by the subjects after using the website and the results showed that the usefulness score of nutrient intake assessment was high. Seventy five percents of the subjects answered that the website might be helpful for weight control, and 71.7% would recommend this website to others, and 68.1% would revisit this website. These results showed that the website might be useful for examining dietary habits, dietary attitudes, food frequency, and dietary intake of college students.
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최보경(Bo Kyoung Choi),윤희용(Hee Yong Youn) 한국정보과학회 2009 정보과학회논문지 : 소프트웨어 및 응용 Vol.36 No.3
인구의 급속한 고령화와 더불어 국민의 복지수준이 향상됨에 따라 건강문제에 대한 효율적인 해결방안으로 병원을 방문하지 않고 의료 서비스를 받는 U-Healthcare의 필요성이 증대되고 있다. 최근 다양한 센서들을 이용하여 사용자의 생체정보 및 주변의 상황정보들을 수집하고 분석해 사용자에게 적절한 서비스를 제공하기 위한 시스템에 대한 연구가 활발히 진행되고 있다. 기존의 U-Healthcare서비스를 위한 시스템들은 특정 서비스만을 대상으로 하여 다른 서비스로의 확장 및 연계가 어렵고, 다수의 사용자를 대상으로 일반화된 서비스를 제공하고 있어 사용자 개개인의 특성을 고려한 서비스를 제공 기능이 미약하다. 본 논문에서는 이러한 문제점을 해결하기 위해 멀티에이전트 기반의 상황인식 에이전트를 이용해 시스템의 확장성을 높이고, GUI기반의 모델링 툴킷 JaUCE를 사용하여 고객 개개인의 상황에 맞는 상황정보를 모델링 함으로써 고객들에게 가장 적합한 상황인식 서비스를 제공한다. 본 논문에서는 제안된 상황인식 에이전트와 모델링 툴킷의 이용하여 상황인식 기반의 U-Silvercare 서비스를 설계하고 구현하였다. U-Healthcare is more efficient as a solving method for health problems rather than visiting the hospital. Recently, systems have been studied to offer appropriate service to user, which gather and analyze biological signals of a user and context information around the user from a variety of sensors. The existing systems for U-Healthcare are based on domain specific service so it is difficult to expand and link to other systems. Also, they lack services focusing on the specific quality of the user, because they offer a general service which targets a lot of users. To address this problem, we expand an extensibility of system using the context-awareness agent based on multi-agents. Also, we provide the suitable services which match with the context information of user to each user using the modeling toolkit JaUCE based on GUI. We design and implement U-Silvercare service to demonstrate the effectiveness of the proposed context-awareness agent and modeling toolkit.
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점진적 저항증가와 점진적 저항감소 운동에서의 표면 근전도 신호 비교
한경주,최보경,Han, Kyoung-Ju,Choi, Bo-Kyung 대한물리치료학회 2008 대한물리치료학회지 Vol.20 No.1
Purpose: This study was undertaken to compare the signal characteristics of surface electromyography (EMG) between progressive resistive increase exercise (PRIE) and progressive resistive decrease exercise (PRDE). Methods: Forty healthy male subjects were randomly assigned to either the PRIE group or the PRDE group. Subjects participated in the PRIE and PRDE methods, with 10 RM for each subject. EMG activity was recorded from the rectus femoris muscle. Outcome data were collected for both groups pre-exercise, immediately post-exercise, then at 5 and 10 minutes post-exercise. Repeated measures 2-way ANOVA was used to determine the statistical difference of the root mean square (RMS) in EMG activity. Results: We showed that RMS values, when compared with pre-exercise, were decreased immediately after exercise and were increased at 5 and 10 minutes after exercise (p<0.05). The RMS values were not significantly different between the two groups (p>0.05). Conclusion: These results can indicate that both the PRIE and PRDE protocols will be improve strength with equivalent efficacy. Further studies are needed to address exercise duration, frequency of exercise sessions, and rest times than the PRIE and PRDE protocols with regard to the changes in strength improvement without a large amount of muscle fatigue.
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권경진 ( Kyoung Jin Kwon ),김도정 ( Do Jung Kim ),김상섭 ( Sang Seop Kim ),최유빈 ( Yu Bin Choi ),김미정 ( Mi Jeong Kim ),최명신 ( Myeong Sin Choi ),최보경 ( Bo Kyung Choi ),김동섭 ( Dong Sup Kim ) 대한화장품학회 2010 대한화장품학회지 Vol.36 No.3
탈모 방지의 목적으로 사용되는 양모제는 현재 우리나라에서 의약외품이며 약사법으로 관리되고 있다. 최근 탈모에 대한 사회적 관심이 증가하면서 양모제에 대한 수요도 증가하고 있는 실정이지만 양모제는 생약추출물, 비타민류, 보존제 등 다양한 종류의 성분이 혼합되어 있어 분석이 쉽지 않다. 본 연구에서는 양모제의 주성분으로 많이 쓰이는 니코틴산아미드, 덱스판테놀, 살리실산, 초산토코페롤, 니코틴산벤질에 대한 동시분석법을 확립하고자 하였다. 시판 중인 양모제를 구입하여 C18 컬럼, 아세토니트릴과 인산염완충액을 용매로 사용하여 HPLC로 분석하였다. 검출은 자외부흡광광도계를 이용하여 220, 270, 300 nm 파장에서 분석하였으며, 12.5 ∼ 800 μg/mL 농도범위에서 검량선을 작성하였다. 회수율은 액상기제의 경우 97.3 ∼ 103.5 % (상대표준편차 0.9 ∼ 2.8 %), 샴푸기제의 경우 101.9 ∼ 115.9 % (상대표준편차 0.7 ∼ 7.7 %)로 양호한 결과를 나타냈다. 시판중인 검체의 함량 시험결과 기준에 적합하였으며, 본 분석법을 이용하여 품질관리 및 추후 양모제 개발에 유용하게 활용함으로써 우수한 품질의 양모제 유통에 크게 기여할 것으로 기대된다. The hair nourisher products are used for prevention of hair loss and classified as quasi-drug in Korea. As concerns about hair loss has been increased, the demand for hair nourisher products has been growing. It is difficult to analyze their main ingredients because they contain various ingredients including natural plant extracts, vitamins, preservatives and exfoliators. The purpose of this study was to develop and validate simultaneous analytical methods of active ingredients in hair nourisher products such as nicotinamide, tocopherol, salicylic acid, dexpanthenol and benzyl nicotinate by HPLC. The active ingredients were separated on a C18 column by using acetonitrile/ phosphate buffer as a mobile phase, and detected at UV 220, 270 and 300 nm. The calibration curve showed linearity in the range of 12.5 ∼ 800 μg/mL and the recoveries were 97.3 ∼ 103.5 % (RSD 0.9 ∼ 2.8 %) in liquid matrix and 101.9 ∼ 115.9 % (RSD 0.7 ∼ 7.7 %) in shampoo matrix. Validated method was applied to hair nourisher products obtained from distribution market. Fortunately, all samples met their criteria. This study might be expected to provide the method for determining active ingredients in hair nourisher products and lead to promote a rapid market entry.
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Saccharomyces cerevisiae에서 번역 개시 인자 eIF1A 돌연변이에 대한 분석
권성훈,김준호,최보경,김나연,최도희,박경준,어정현,배성호,Kwon, Sung-Hun,Kim, Jun-Ho,Choi, Bo-Kyung,Kim, Na-Yeon,Choi, Do-Hee,Park, Kyoung-Jun,Eoh, Jung-Hyun,Bae, Sung-Ho 한국미생물학회 2009 미생물학회지 Vol.45 No.3
번역 개시 인자 eIF1A는 진핵생물에서 43S preinitiation complex 형성을 비롯한 번역 개시 과정의 여러 단계에서 필수적인 역할을 하며, 잘 보존된 oligonucleotide-binding (OB) fold를 가지고 있는 단백질이다. 본 연구진은 이전 연구에서 eIF1A가 RNA annealing 활성을 가지고 있으며 double-stranded RNA에 결합하여 안정된 복합체를 형성한다는 것을 발견한 바 있다. 본 연구에서는 이러한 활성을 나타내는데 필요한 active site를 찾고, 이러한 활성이 효모의 성장에 필수적인 기능인지를 알아보기 위하여 여러 가지 돌연변이를 제조하였다. N-말단과 C-말단은 제거되었지만 완전한 OB-fold를 가지고 있는 eIF1A($\Delta$T)는 RNA annealing 활성을 보이는 반면, OB-fold에 돌연변이가 도입된 단백질들은 모두 활성이 사라졌다. 또한, R57D 돌연변이를 제외한 모든 OB-fold 돌연변이는 dsRNA에도 결합하지 않았다. 이러한 결과는 eIF1A의 RNA annealing 활성과 dsRNA 결합에는 완전한 OB-fold domain이 필요하다는 것을 의미한다. 돌연변이들이 효모의 성장에 미치는 영향을 조사한 결과, RNA annealing 활성과 효모의 성장은 뚜렷한 연관성이 없었으며, 적어도 R57D와 K94D 경우에는 돌연변이가 성장하지 못하는 원인이 생체 내 eIF1A 단백질의 안정성과 관계있는 것으로 생각된다. Translation initiation factor eIF1A performs essential functions in various initiation steps including 43S preinitiation complex formation in eukaryotes, and contains a highly conserved oligonucleotide-binding (OB) fold. In our previous study, we discovered that eIF1A possesses RNA annealing activity and forms a stable complex with double-stranded RNA. In this study, we initiated site-directed mutations in eIF1A to find the active sites for these biochemical activities and to investigate whether they are essential functions for yeast cell growth. A truncated protein, eIF1A($\Delta$T), devoid of both N- and C-terminal domains but containing an intact OB-fold exhibited RNA annealing activity. In contrast, all point mutations in OB-fold domain, except R57D, impaired both RNA annealing and dsRNA binding activities, indicating that the intact OB-fold domain is required for both activities. Viabilities of the mutant yeast cells were not correlated with RNA annealing activity but with the in vivo protein stabilities in the case of R57D and K94D.
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정상 신기능의 좌측 복통 환자에서 진단된 원인 불명의 일측성 후복막 섬유화증 1예
이문형 ( Moon Hyoung Lee ),문경협 ( Kyoung Hyoub Moon ),김범 ( Beom Kim ),이동영 ( Dong Young Lee ),시원근 ( Won Keun Si ),황진아 ( Jin Ah Hwang ),최보경 ( Bo Kyoung Choi ),서강흠 ( Kang Hum Seo ) 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.3
Retroperitoneal fibrosis is a disease characterized by proliferation of fibro-inflammatory tissue, which mainly encloses the abdominal aorta, iliac arteries and (enlarges to the retroperitoneum to surrounds) ureters. Two leading pathogenesis are an exacerbated local inflammatory reaction to aortic atherosclerosis and a manifestation of systemic autoimmune disease. Because of insidious disease course, most cases are diagnosed late when bilateral urinary obstruction caused oliguria and symptoms related to uremia. In this case, the patient complained left flank pain which might have been caused by left ureter stone, but through abdominal CT scan, the patient was diagnosed as left unilateral retroperitoneal fibrosis. Abdominal CT scan showed encircling mass around abdominal aorta and left ureter with hydronephrosis. The patient had no underlying disease and didn`t take any medication; she was diagnosed as idiopathic unilateral retroperitoneal fibrosis and started prednisolone, 40 mg daily. Three months have passed since the therapy was started; most fibrous tissue was disappeared, hydronephrosis was resolved and flank pain was relieved.
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최보경, 현태선 충북대학교 생활과학연구소 2012 생활과학연구논총 Vol.16 No.2
The purpose of this study was to investigate dietary habits and nutrient intake of college students through 'idiet' website and evaluate satisfaction of the website. The subjects were 166 students who registered 'food and nutrition' as a general education course in Chungbuk National University. Dietary habits, dietary attitudes, food frequency, and dietary intake were investigated through the 'idiet' website by himself/herself. More than two thirds(69.3%) of the subjects were categorized as 'poor' in dietary habits, and 36.7% were categorized as 'poor' in dietary attitudes. Nutrient intakes were estimated on the website when the students chose the name and the amount of the foods they ate during 24 hours with the help of real-size photos provided on the website. Mean daily energy intakes were 2,146 kcal, and 1,667 kcal in male and female students, respectively, which were comparable with those published in the previous studies estimated though a 24-hour recall or a food record method. Mean daily intakes of vitamin C, riboflavin and calcium were less than 75% of Recommended Intakes. Nutrient intakes of the subjects who were categorized as 'good' in dietary habits and food frequency were significantly higher than those who were categorized as 'poor'. The usefulness of the contents were evaluated by the subjects after using the website and the results showed that the usefulness score of nutrient intake assessment was high. Seventy five percents of the subjects answered that the website might be helpful for weight control, and 71.7% would recommend this website to others, and 68.1% would revisit this website. These results showed that the website might be useful for examining dietary habits, dietary attitudes, food frequency, and dietary intake of college students.
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