당뇨병을 가진 노인 환자에서의 우울증 유병률 조사

최범성,김세웅,박선철,심세훈,송후림,장성혜,최재성,이호성,김여주,박상호,권영준,이화영 대한신경정신의학회 2015 신경정신의학 Vol.54 No.4

Objectives Depression is commonly comorbid in elderly patients with physical illness. This study examined the prevalence of depression in the elderly with Diabetes Mellitus (DM). Methods Eighty-nine patients, over 60 years old, with DM were enrolled. The medical and psy¬chiatric history, Hamilton Rating Scale for Depression (HDRS), Patient Health Questionnaire-9 (PHQ-9), Geriatric Depression Scale-Short form Korean (GDS-SF-K), and Mini-Mental Status Ex¬amination Korean version were examined. Results The prevalence of depression was estimated as 21.3% (male 4.5% ; female 16.9%) in HDRS, 32.6% (male 9.0% ; female 23.6%) in PHQ-9, and 24.7% (male 5.6% ; female 19.1%) in GDS-SF-K. Conclusion The self-reporting scale, such as GDS-SF-K, PHQ-9 is an effective screening test for depression. The prevalence of elderly depression with DM ranged from 20% to 30%, the prev¬alence of depression is almost three times more common in women.

화학적 거세의 의료윤리적 관점

최범성,임명호 한국의료윤리학회 2016 한국의료윤리학회지 Vol.19 No.2

성적가해자에 대한 대중적인 관심은 오래 전부터 있었으나 가해자의 윤리적 문제에 대한 관심과 연구는 매우 적었다. 그러나 최근에는 성적 가해자의 윤리에 대한 연구보고가 증가하고 있으며 가해자의 인권에 관한 문제제기도 이루어지고 있다. 성적 가해자에 대한 치료의 한 방법으로 외과적 거세 및 화학적 거세치료 즉 성충동조절 약물치료 등의 방법이 있지만 공공의 안전을 위해서 범법자에 대한 벌이 필요하다는 의견과 임상적으로 가장 효과적인 치료방법을 선택해야한다는 의견이 서로 상충하고 있다. 본 연구자는 화학적 거세치료가 점차적으로 증가되고 있는 현시점에서 첫째, 화학적 거세 즉 성폭력 범죄자의 성충동약물치료에 대한 의학적 효능과 부작용을 알아보고, 둘째, 의료 윤리적 관점에서 화학적 거세의 주된 문제점들을 문답형으로 고찰하고자 하였다. Although the topic of sexual offense has received increased public attention in recent years, there has been relatively little research on the ethical issues related to the medical treatment of sexual offenders. Treatment options for sexual offenders include surgical castration and chemical castration through the use of sexual impulse control drugs. Opinions vary on the most effective and appropriate methods for treating sexual offenders. In this article we examine the side-effects of the drugs used in chemical castration and discuss the main ethical issues involved in chemical castration.

우울증 치료에서 빠른 효과와 적은 부작용을 가진 새로운 N-Methyl-D-Aspartate(NMDA) 수용체 길항제

최범성,이화영,Choi, Bum-Sung,Lee, Hwa-Young 대한생물정신의학회 2015 생물정신의학 Vol.22 No.4

Mood disorder is a common psychiatric illness with a high lifetime prevalence in the general population. Many prescribed antidepressants modulate monoamine neurotransmitters including serotonin, norepinephrine and dopamine. There has been greater focus on the major excitatory neurotransmitter in the human brain, glutamate, in the pathophysiology and treatment of major depressive disorder (MDD). Recently, ketamine, an N-methyl-D-aspartate receptor antagonist, has received attention and has been investigated for clinical trials and neurobiological studies. In this article, we will review the clinical evidence for glutamatergic dysfunction in MDD, the progress with ketamine as a rapidly acting antidepressant, and other N-methyl-D-aspartate receptor antagonist for treatment-resistant depression.

묶음 예약 배달 시스템

최범성,김경재,김미령,이재호 대한경영학회 2018 대한경영학회 학술발표대회 발표논문집 Vol.2018 No.2

Hybrid A* 와 강화학습을 이용한 다중 에이전트 경로 계획

최범성(Beomseong Choi),최승원(Seungwon Choi),류재언(Jaeun Ryu),허건수(Kunsoo Huh) 한국자동차공학회 2022 한국자동차공학회 학술대회 및 전시회 Vol.2022 No.11

As autonomous driving technology has recently expanded and increased, the need for a path planning technology considering interaction with surrounding agents is increasing. In addition, Multi-Agent path planning is essential when a large number of autonomous driving mobility drives in a narrow environment. In particular, Multi-Agent path planning requires collision avoidance algorithms for dynamic obstacles. Therefore, in this paper, we propose a decentralized Multi-Agent path planning algorithm considering their interactions with surrounding agents. In global path planning, we use Hybrid A* to allow creating physically feasible paths by considering the kinematic characteristics of mobility. In local path planning, we used Proximal Policy Optimization(PPO), one of the reinforcement learning methods, to learn interactions with surrounding agents. The proposed algorithm is trained and evaluated through Unity ML-Agents. As a result of the simulation, we find that the success rate increases due to fewer collisions with surrounding agents than the traditionally frequently used RRT*-based path planning methods.

인터넷 중독과 주의력결핍 과잉행동장애 환아 어머니의 양육 스트레스 및 효능감

최범성(Bum-Sung Choi),김봉석(Bongseog Kim) 대한소아청소년정신의학회 2010 소아청소년정신의학 Vol.21 No.2

Objectives:The purpose of this study was to compare levels of parenting stress and efficacy in mothers of children suffering from attention-deficit hyperactivity disorder (ADHD) and internet addiction disorder (IAD), mothers of children with ADHD alone only, and those with normal children. Methods:Participants were composed of 25 mothers of children with ADHD and IAD, 35 mothers of children with ADHD alone, and 50 mothers of normal children. They completed the Parenting Stress Index (PSI) and Parenting Sense of Competence (PSOC). Results:In comparison with the mothers of normal children, the mothers of children with ADHD and IAD and the mothers of children with ADHD alone showed significantly higher levels of parenting stress and lower parenting efficacy. However, a comparison of mothers of children with ADHD and IAD with those of children with ADHD alone did not show any significant differences in their levels of parenting stress or efficacy. Conclusion:Mothers of children with ADHD, regardless of the presence of IAD exhibited a higher level of parenting stress and a lower level of parenting efficacy than mothers of normal children.

소아청소년 양극성장애 환자에서 리튬 치료에 따른 소변 오스몰랄농도의 변화

정지운,최범성,김대욱,유은라,허성영,김성곤,김지훈 대한신경정신의학회 2020 신경정신의학 Vol.59 No.4

Objectives Bipolar disorder has a high rate of recurrence, which can cause problems such as declines in cognitive and social functions. Lithium is the primary medication for preventing recurrence, but the medication compliance is poor owing to side effects that include diarrhea, tremor, polyuria, polydipsia, diabetes insipidus, increased creatinine level, and weight gain. Polyuria and polydipsia also cause voluntary discontinuation of the medication. However, no domestic and international studies have evaluated the direct correlation between lithium therapy and polydipsia in pediatric patients. Therefore, we assessed this relationship by evaluating urine osmolality changes after lithium administration in pediatric patients. Methods This study focused on patients admitted to the Department of Psychiatry, Pusan National University Yangsan Hospital. Patients had bipolar disorder types I or II and other specified bipolar disorders based on the DSM-5, criteria at discharge from December 1, 2018, to April 31, 2020. Urine osmolarity changes from admission to discharge in the patients who used lithium for the first time after admission were reviewed. Results For 47 patients, the change in osmolality was statistically significant (mean, 203.32± 280.68; p<0.001) and significantly higher in those aged <14 years than in those aged ≥14 years (p=0.038). Antipsychotic use and sex-related differences did not affect urine osmolality. Conclusion The first-time users of lithium had significantly reduced urine osmolality at discharge. Considering the lithium effect on the kidneys, a prospective study to identify the relationship between lithium use and polydipsia is necessary.

자폐스펙트럼장애 아동에서 통합적 조기중재치료가 언어 발달에 미치는 효과에 대한 고찰

박현우,최범성,김지훈 학습자중심교과교육학회 2024 학습자중심교과교육연구 Vol.24 No.1

Objectives The purpose of this study is to provide information on the therapeutic effect of integrated early intervention by comprehensively performing speech therapy, applied behavior analysis, and sensory integration therapy in children with autism spectrum disorder. Methods 30 children treated for more than 6 months at the P University Hospital's Autism and developmental disorder treatment center were evaluated at the mean monthly language growth rate after 6 months of integrated intervention. Results At the start of treatment, the mean monthly growth rate of the receptive languages was 0.35 months (SD=.22, S.E. Mean=.04), and the mean monthly growth rate of the expressive languages was 0.33 months (SD=.20, S.E. Mean=.04), whereas the mean monthly growth rate of the receptive languages after 6 months’ treatment was 1.31 months (SD=1.61, S.E. Mean=.29), and the mean monthly growth rate of the expressive languages was 1.13 months (SD=1.31, S.E. Mean=.24) and paired t-tests showed significant differences. Conclusions This study is significant in that it established the evidence base for integrated early intervention therapy by confirming that integrated early intervention therapy is effective for children's language growth.

자폐스펙트럼장애 아동의 성별, 출생체중, 재태 연령, 출생 방법에 따른 자폐 증상 심각도 차이: 후향적 분석

전재효,최범성,김지훈,박현우 학습자중심교과교육학회 2024 학습자중심교과교육연구 Vol.24 No.1

Objectives This study is diagnosed to find out differences in child's level of adaptive behavior and symptom severity according to gender, birth weight, gestational age, and type of birth. Methods This study is a retrospective analysis of 71 children with autism spectrum disorder. K-Vineland-II and K-CARS2-ST tests were performed, and descriptive analysis of each variable, correlation analyses, and multiple regression analysis were performed. Results In terms of gender differences, higher scores were found in girls only in the K-CARS2-ST test (p=0.004). No significant difference was found in the two tests in birth weight and type of birth. A weak negative correlation was found in the K-CARS2-ST test in the gestational age (r=-0.282, p=0.022). Conclusions This study demonstrated that there was no statistically significant correlation between the factors determined at the moment a child is born and the level of adaptive behavior or the autism symptom severity that the child shows afterwards. This can be used as a basis for the argument that more attention and effort are needed for parenting, education, and treatment for the children with autism spectrum disorder.

Design and Analysis of Permanent Magnet Synchronous Generator Considering Magnetically Coupled Turbine-Rotor System

김병옥,최범성,김정만,조한욱 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.3

In this paper, design and analysis of permanent magnet synchronous generator for ocean thermal energy conversion (OTEC) considering magnetically coupled turbine-rotor system is discussed. In particular, the rotor dynamics considering bearing span and journal shaft diameter is highlighted. The two topologies of permanent magnet synchronous generator with magnetic coupling are employed for comparison of computed rotor dynamics and generating characteristics. The analysis results show that the critical speed of the turbine-rotor system is higher when the rotor is coupled by magnetically coupling. Finally, the experimental results confirmed the validity of the proposed design and analysis scheme and successful development.