당뇨병을 가진 노인 환자에서의 우울증 유병률 조사

최범성,김세웅,박선철,심세훈,송후림,장성혜,최재성,이호성,김여주,박상호,권영준,이화영 대한신경정신의학회 2015 신경정신의학 Vol.54 No.4

Objectives Depression is commonly comorbid in elderly patients with physical illness. This study examined the prevalence of depression in the elderly with Diabetes Mellitus (DM). Methods Eighty-nine patients, over 60 years old, with DM were enrolled. The medical and psy¬chiatric history, Hamilton Rating Scale for Depression (HDRS), Patient Health Questionnaire-9 (PHQ-9), Geriatric Depression Scale-Short form Korean (GDS-SF-K), and Mini-Mental Status Ex¬amination Korean version were examined. Results The prevalence of depression was estimated as 21.3% (male 4.5% ; female 16.9%) in HDRS, 32.6% (male 9.0% ; female 23.6%) in PHQ-9, and 24.7% (male 5.6% ; female 19.1%) in GDS-SF-K. Conclusion The self-reporting scale, such as GDS-SF-K, PHQ-9 is an effective screening test for depression. The prevalence of elderly depression with DM ranged from 20% to 30%, the prev¬alence of depression is almost three times more common in women.

화학적 거세의 의료윤리적 관점

최범성,임명호 한국의료윤리학회 2016 한국의료윤리학회지 Vol.19 No.2

성적가해자에 대한 대중적인 관심은 오래 전부터 있었으나 가해자의 윤리적 문제에 대한 관심과 연구는 매우 적었다. 그러나 최근에는 성적 가해자의 윤리에 대한 연구보고가 증가하고 있으며 가해자의 인권에 관한 문제제기도 이루어지고 있다. 성적 가해자에 대한 치료의 한 방법으로 외과적 거세 및 화학적 거세치료 즉 성충동조절 약물치료 등의 방법이 있지만 공공의 안전을 위해서 범법자에 대한 벌이 필요하다는 의견과 임상적으로 가장 효과적인 치료방법을 선택해야한다는 의견이 서로 상충하고 있다. 본 연구자는 화학적 거세치료가 점차적으로 증가되고 있는 현시점에서 첫째, 화학적 거세 즉 성폭력 범죄자의 성충동약물치료에 대한 의학적 효능과 부작용을 알아보고, 둘째, 의료 윤리적 관점에서 화학적 거세의 주된 문제점들을 문답형으로 고찰하고자 하였다. Although the topic of sexual offense has received increased public attention in recent years, there has been relatively little research on the ethical issues related to the medical treatment of sexual offenders. Treatment options for sexual offenders include surgical castration and chemical castration through the use of sexual impulse control drugs. Opinions vary on the most effective and appropriate methods for treating sexual offenders. In this article we examine the side-effects of the drugs used in chemical castration and discuss the main ethical issues involved in chemical castration.

우울증 치료에서 빠른 효과와 적은 부작용을 가진 새로운 N-Methyl-D-Aspartate(NMDA) 수용체 길항제

최범성,이화영,Choi, Bum-Sung,Lee, Hwa-Young 대한생물정신의학회 2015 생물정신의학 Vol.22 No.4

Mood disorder is a common psychiatric illness with a high lifetime prevalence in the general population. Many prescribed antidepressants modulate monoamine neurotransmitters including serotonin, norepinephrine and dopamine. There has been greater focus on the major excitatory neurotransmitter in the human brain, glutamate, in the pathophysiology and treatment of major depressive disorder (MDD). Recently, ketamine, an N-methyl-D-aspartate receptor antagonist, has received attention and has been investigated for clinical trials and neurobiological studies. In this article, we will review the clinical evidence for glutamatergic dysfunction in MDD, the progress with ketamine as a rapidly acting antidepressant, and other N-methyl-D-aspartate receptor antagonist for treatment-resistant depression.

우울증에서 에스케타민의 임상 적용: 서술적 문헌 고찰

최범성,이화영 대한생물정신의학회 2024 생물정신의학 Vol.31 No.2

Mood disorders are a major cause of morbidity. Many patients experience treatment-resistant depression, and suicide rates are on the rise. There is a critical need for faster-acting and more effective antidepressants. After decades of research, esketamine, initially used as an anesthetic, has begun to be used as an outpatient treatment for major depressive disorder. Esketamine, an N-methyl-D-aspartate receptor antagonist, directly targets the glutamate system, rapidly improving mood symptoms and reducing suicidal ideation. Esketamine has demonstrated superior efficacy in reducing depressive symptoms more quickly than traditional oral antidepressant monotherapy, with a favorable risk-benefit profile. Reported side effects include sedation, dizziness, dissociative reactions, and increased blood pressure, though these effects are generally limited to the monitoring period of approximately two hours following administration.

묶음 예약 배달 시스템

최범성,김경재,김미령,이재호 대한경영학회 2018 대한경영학회 학술발표대회 발표논문집 Vol.2018 No.2

인터넷 중독과 주의력결핍 과잉행동장애 환아 어머니의 양육 스트레스 및 효능감

최범성(Bum-Sung Choi),김봉석(Bongseog Kim) 대한소아청소년정신의학회 2010 소아청소년정신의학 Vol.21 No.2

Objectives:The purpose of this study was to compare levels of parenting stress and efficacy in mothers of children suffering from attention-deficit hyperactivity disorder (ADHD) and internet addiction disorder (IAD), mothers of children with ADHD alone only, and those with normal children. Methods:Participants were composed of 25 mothers of children with ADHD and IAD, 35 mothers of children with ADHD alone, and 50 mothers of normal children. They completed the Parenting Stress Index (PSI) and Parenting Sense of Competence (PSOC). Results:In comparison with the mothers of normal children, the mothers of children with ADHD and IAD and the mothers of children with ADHD alone showed significantly higher levels of parenting stress and lower parenting efficacy. However, a comparison of mothers of children with ADHD and IAD with those of children with ADHD alone did not show any significant differences in their levels of parenting stress or efficacy. Conclusion:Mothers of children with ADHD, regardless of the presence of IAD exhibited a higher level of parenting stress and a lower level of parenting efficacy than mothers of normal children.

Hybrid A* 와 강화학습을 이용한 다중 에이전트 경로 계획

최범성(Beomseong Choi),최승원(Seungwon Choi),류재언(Jaeun Ryu),허건수(Kunsoo Huh) 한국자동차공학회 2022 한국자동차공학회 학술대회 및 전시회 Vol.2022 No.11

As autonomous driving technology has recently expanded and increased, the need for a path planning technology considering interaction with surrounding agents is increasing. In addition, Multi-Agent path planning is essential when a large number of autonomous driving mobility drives in a narrow environment. In particular, Multi-Agent path planning requires collision avoidance algorithms for dynamic obstacles. Therefore, in this paper, we propose a decentralized Multi-Agent path planning algorithm considering their interactions with surrounding agents. In global path planning, we use Hybrid A* to allow creating physically feasible paths by considering the kinematic characteristics of mobility. In local path planning, we used Proximal Policy Optimization(PPO), one of the reinforcement learning methods, to learn interactions with surrounding agents. The proposed algorithm is trained and evaluated through Unity ML-Agents. As a result of the simulation, we find that the success rate increases due to fewer collisions with surrounding agents than the traditionally frequently used RRT*-based path planning methods.

ADHD 학생의 동네환경과 특별활동의 경험에 대한 비교연구

이재영,최범성,강동묵,김지훈,Lee, Jae-Young,Choi, Bum-Sung,Kang, Dong-mug,Kim, Ji-Hoon 대한생물정신의학회 2018 생물정신의학 Vol.25 No.3

Objectives The purpose of this study is to investigate the differences between a attention deficit hyperactivity disorder (ADHD) group and a general student group in terms of the perception of the residential environment and periodic activities outside the classroom. Methods The patient group consisted of 62 outpatients or inpatients at the Department of Pediatric Psychiatry, and 49 patients diagnosed with ADHD were selected. For the control group, 3727 youths in elementary schools, middle schools, and high schools of one city were asked to fill out questionnaires. Of the 1717 respondents who responded to the questionnaires, 245 were selected for a patient-controlled study. The differences between the patient group and the control group were compared using the chi-squared test (${\chi}^2$ test). Results There was a significant difference between the patient group and the control group in areas where students responded by "My neighborhood is dirty and littered (p < 0.05)". There was also a significant difference between the patient group and the control group in terms of having more than one club activity per month (p < 0.05). Conclusions It was found that the patients with ADHD are more aware of perceived negative aspects of the area in which they reside, thus reflecting their anxiety. In addition, it was also found that the patient group did not partake in as many social activities as the control group.

텍스트마이닝을 활용한 발달장애 신문기사 분석: 조기선별과 조기중재를 중심으로

이상아,최범성,최진혁 한국특수아동학회 2020 특수아동교육연구 Vol.22 No.1

Purpose: The purpose of this study was to analyze newspaper articles related to early screening and early intervention of individuals with developmental disabilities via the text mining method. Method: The analysis targets 39 newspaper articles from Jan. 2014 to Sept. 2019. Newspaper articles were ected through Big KindsⓇ and analyzed through Textom and UCINET. Results: First, it was identified that the interest in early screening and early intervention of developmental disabilities have maintained. Second, the ‘developmental disabilities’ term was commonly used after the activation of the Developmental Disability Support Act. Third, the word ‘developmental disabilities’ appeared with the highest frequency. Fourth, in the N-gram analysis, the relationship of upper related words was shown as ‘developmental disabilities - child’, ‘developmental disabilities - family’ and ‘developmental disabilities - brain’. Fifth, in the semantic network analysis, influential words appeared as ‘developmental disabilities’, ‘child’ and ‘therapy’. Sixth, the CONCOR analysis has divided the major clusters by the categories of ‘characteristics and support of developmental disabilities’, ‘early intervention’ and ‘government policy’. Conclusion: Through this study, we were able to find a way forward. 연구목적: 본 연구에서는 텍스트마이닝을 활용하여 발달장애 조기선별과 조기중재 관련 신문기사를 분석하여 우리 사회의 인식 특성을 파악하는 것을 목적으로 한다. 연구방법: 분석대상은 2014년부터 2019년 9월까지의 신문기사 39건으로 하였다. 분석자료는 뉴스 빅데이터 분석 서비스에서 수집하고, 텍스톰과 UCINET을 활용하여 분석하였다. 연구결과: 첫째, 우리 사회는 발달장애 조기선별과 조기중재와 관련해 지속적인 관심을 보이는 것으로 나타났다. 둘째, 발달장애에 대한 용어는 발달장애인법이 통과된 후 범용적으로 사용된 것을 알 수 있다. 셋째, 주요 단어 중 ‘발달장애’가 가장 높은 빈도로 등장했다. 넷째, N-gram 분석에서 상위의 연관 있는 단어의 관계는 ‘발달장애-아동’, ‘발달장애-가족’, ‘발달장애-뇌’로 나타났다. 다섯째, 의미연결망 분석에서 영향력 있는 단어는 ‘발달장애’, ‘아동’, ‘치료’로 나타났다. 여섯째, CONCOR 분석으로 ‘발달장애 특징과 지원’, ‘조기중재’, ‘정부정책’의 범주별 주요 클러스터가 구분되었다. 결론: 본 연구는 발달장애 조기선별과 조기주재에 대한 전반적인 사회의 인식을 탐색하고, 앞으로 나아갈 방향성을 파악하였다는 것에 의의가 있다.

신경 발달 장애에서 정신병 혹은 양극성 장애로의 전환 확률

안성은,최범성,유은라,정지운,허성영 대한조현병학회 2022 대한조현병학회지 Vol.25 No.2

Objectives: The clinical trajectories of adolescent-onset psychosis and bipolar disorder are worse than that of adult-onset cases. Although psychosis and bipolar disorder are more prevalent among those with neurodevelopmental disorders such as ADHD and autism spectrum disorder compared with the general population, the incidence during adolescence has not yet been explored. Methods: Out of 3,730 patients who visited the Department of Pediatric Psychiatry at Pusan National University Yangsan Hos- pital between November 2008 and May 2021, patients with neurodevelopmental disorders who did not meet the criteria for psy- chosis or bipolar disorder and had at least one year of the follow-up period were selected. A Kaplan-Meier analysis was performed to examine the cumulative incidence of psychosis and bipolar disorder in patients with neurodevelopmental disorders. Results: The sample included 591 patients with neurodevelopmental disorders (mean age 12.6 years, range 10-18 years). The 9-years cumulative incidences of psychosis and bipolar disorder are 1.3% (95% CI=0.2%-2.4%), 11.6% (95% CI=7.4%-15.6%), respectively. Conclusion: Patients with neurodevelopmental disorders showed a high incidence of psychosis and bipolar disorder during ado- lescence. This suggests that patients diagnosed with neurodevelopmental disorders should be continuously evaluated and moni- tored of the occurrence of comorbidities during adolescence.