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소동물 X-선 진단에 있어서 광범위 관용도 필림의 이용에 관하여
최민철,Choi Min-Cheol 한국임상수의학회 1992 한국임상수의학회지 Vol.9 No.2
To elucidate the applicability of the wide latitude X-ray film for radiographic diagnosis and treatment of diseases in small animals, the quality of the wide latitude film was compared with that of the standard latitude film which is commonly used in veterinary clinic. The images of head, neck, thorax, abdomen, extremities and joints were radiographed with the wide latitude and standard latitude film in fourteen dogs. In soft tissues such as abdominal organs, lung, skin, mammary glands, the clearer and higher contrast of the image was observed on the wide latitude film. And these advantages were more apparent in pneumoeritoneography. Therefore. it can be suggested that the wide latitude film is practically useful for the evaluation of the images of soft tissues, and also can be used on hard tissue radiography with the same quality as the standard latitude film.
Aloe vera가 Cobalt-60 gamma선 조사를 받은 쥐의 혈액성분에 미치는 영향
최민철,Choi Min-chul 대한수의사회 1990 대한수의사회지 Vol.26 No.1
The effect of Aloe vera administration(500mg/kg, P.O.) for 21 days on the total white blood cell, packed cell volume, hemoglobin, total protein, serum glutamic pyruvic transaminase and sorbitol dehydrogenase values in cobalt-60 gamma irradiated rats was s
쥐에서 Sodium Carboxymethylcellulose 및 Dextran 70의 유착방지 효과
최민철,강태영,이효종,Choi Min-Cheol,Kang Tae-Young,Lee Hyo-Jong 한국임상수의학회 1992 한국임상수의학회지 Vol.9 No.2
The 2% Sodium carboxymethylcellulose(CMC) and 10% Dextran 70 solutions were evaluated for the prevention of postoperative adhesion formation in rats. The artificial injuries(2cm longitudinal incision and suture) were performed on the colon and uterine horns in the rats. 2% CMC and 10% dextran solutions were applied to the injured surfaces and peritoneal cavity in the rats. Ten days later, there were significant difference(p<0.01) in the prevention of adhesion formation between control and treated groups(2% CMC and 10% dextran 70), but the,$\boxUl$ was no significant difference between 2% CMC and 10% dextran 70 treated groups. The increment rate of body weight in the 10% dextran 70 treated group was lower than 2% CMC and control groups(p<0.05.). A positive correlation was found between the severity of adhesion formation and the plasma fibrinogen concentration in blood.
Comparative evaluation of renal size on radiography and ultrasonography in rabbits
최민철,윤희준,이효종,강태영,Choi, Min-cheol,Yin, Xi-jun,Lee, Hyo-jong,Kang, Tae-young The Korean Society of Veterinary Science 1996 大韓獸醫學會誌 Vol.36 No.4
토끼에서 신장의 크기(길이, 폭 및 높이)를 측정하고 이에 대한 기본자료로 삼고자 53마리의 토끼(Newzealand White)의 신장을 방사선 촬영과 초음파 신장촬영 그리고 신장을 적출하여 실제 길이를 재고 이들간의 측정치를 비교하였다. 방사선 촬영에서는 우측신장은 T13-L2에서 관찰되었고 좌측신장은 L2-L4에서 관찰되었다. 초음파 신장촬영상에서는 신장 피질은 작고 균등하며 주변조직에 비하여 저에코상을 보였고 신장의 신우는 무에코 내지는 약간의 저에코상을 보였다. 토끼의 좌측신장에서 길이, 폭 및 높이는 각각 $35.84{\pm}3.12(mean{\pm}SD)$, $23.52{\pm}3.21$ 및 $15.11{\pm}2.58cm$ 였으며 우측신장에서는 $36.02{\pm}3.42$, $23.69{\pm}3.50$ 및 $14.13{\pm}3.55cm$ 이었다. 방사선 사진상에서 양쪽 신장의 길이와 폭은 실제 크기에 비하여 약간 확대되었으며(102~104%), 초음파신장 촬영상에서 양쪽 신장의 길이, 폭 및 높이는 실제 크기에 비하여 적게 축소된 상을 보였다(70~96%). 복배상 방사선 사진에서 신장의 길이와 폭의 제2요추 길이의 대비에서 1.85와 1.25배로 나타났다. 체중과 신장의 각 측정치와의 상관관계에서는 서로간에 유의치 있는 상관관계가 있었다. Renal size(length, width and height) of rabbits was measured by radiographs and nephrosonograms and compared with actual size. After measuring on the radiographs and nephrograms, both kidneys were removed from the body and actual size was also measured. On radiographs, right kidney was observed at the T13-L2 vertebrae and left kidney was at L2-L4 vertebrae. On nephrosonograms, the renal cortex was visible as small, homogenous echoes that were hypoechoic relative to the surrounding tissues, whereas the renal medulla was anechoic to slightly hypoechoic. The actual length, width and height of the left kidney were $35.84{\pm}3.12(mean{\pm}SD)$, $23.52{\pm}3.21$, $15.11{\pm}2.58cm$, respectively, whereas those of the right kidney were $36.02{\pm}3.42$, $23.69{\pm}3.50$ and $14.13{\pm}3.55cm$, respectively. On radiographs, the length and width of both kidneys were a little magnified(102-104%) when compared to actual size. On nephrosonograms, the length, width and height of bothkidneys were lessened(70-96 %) when compared to actual size. The length and width of kidney were 1.85 and 1.25 times the length of the second lumbar vertebrae on the ventrodorsal view. In correlation and correlation coefficient of body weight with the renal size, the body weight and renal size were significantly correlated with each other other(p<0.01) and the correlation coefficents of body weight with left, right and both Kindneys were 0.748, 0.794 and 0.859, respectively.
최민철,이효종,조성근,강태영,원현희,Choi, Min-cheol,Lee, Hyo-jong,Cho, Seong-keun,Kang, Tae-yung,Won, Hyun-hui 대한수의학회 1999 大韓獸醫學會誌 Vol.39 No.6
This study was carried out to develop a newly designed ovum pick-up(OPU) instrument for ultrasound-guided transvaginal follicular aspiration in cows. This new instrument consists of out- & inner-layer stainless pipes and a grip with a trigger(hand) switch. Some gauge types of disposable needles and tubes can be attached to this inner pipe. With this instrument, while grasping an ovary with one hand, the other hand can handle in apiration and vacuum on/off with the least assitant's help. With this instrument the mean recovery rate of bovine follicular oocytes was 45.2%. In recovered oocytes, usable oocytes(Grade I & II) were 30.4% and this rate meant 1.4 oocytes per ovary. For 30 days after initial aspiration with this instrument, some adverse effects such as adhesion, hemorrhage, hematoma and other mass formation in/with ovaries were also examined by rectal examination, ultrasonographic and endoscopic images. Adhesion was found in one ovary 1 week after aspiration, and hemorrhagic lesion was found 1-2 days and petechia were found 3-5 days after aspiration and there was no remarkable adverse effects. It was found that this instrument could be applicable and safe for ovum pick-up in cows.
최민철,Choi Min-chul 대한수의사회 1990 대한수의사회지 Vol.26 No.1
A dog which Showed dry muzzle, coughing, dyspnea, weight loss and exercise intolerance was clinically examined. Dirofilaria immitis infection was determined by hematological findings, radiographic evaluation and detection of microfilaria with modified Kno
쥐에서 Carboxymethylcellulose 및 Ibuprofen을 이용한 유착형성 방지에 관한 연구
최민철,이효종,김곤섭,Choi Min-Cheol,Lee Hyo-Jong,Kim Gon-Sup 한국임상수의학회 1993 한국임상수의학회지 Vol.10 No.2
With the use of a rat surgical model, the ability of carboxymethylcellulose and ibuprofen in the reduction of abdominal adhesion was examined. Seventy seven female rats were randomly divided into 7 groups : (1) control, (2) 2% CMC, (3) 3% CMC, (4) ibuprofen 25mg, (5) ibuprofen 50mg, (6) combination of ibuprofen 25mg and 2% CMC and(7) combination of ibuprofen 50mg and 3%, CMC. Following induction of abrasion injuries on ileum, colon and both uterine horns with a surgical blads, the rats in groups (2), (6) were infused with 2% CMC solution singly or in combined Infection of 25 mg/kg of ibuprofen for three consecutive days, the rats In groups (3), (7) were infused with 3% CMC solution singly or In combined Injection of 50mg/kg of ibuprofen for three consecutive days. The rats in groups (4), (5) were injected only with 25 mg or 50 mg/kg of ibuprofen for three consecutive days. After 10 days the abdominal cavities were opened and the appearance of formed adhesion were graded. The changes of body weight, CBC and blood chemicals were also evaluated at 3, 6 and 10 days after operation. In ileum, the rats in the groups (2), (6) and (7) showed less adhesion formation. In colon, there were significant differences(p<0.05) in adhesion formation in all treated groups as compared to control. In both uterine horns, there were significant decrease(p<0.05) of adhesion formation in groups(2), (6) and (7) in comparison with other groups. The increasing rate of body weight was evident in group (3) and fibrinogen concentrations at 6 and 10 days revealed significant decrease (p<0.01) in group (7), whereas there was no consistent change in CBC and blood chemicals. Therefore, it can be sugested that the infusion of 2% CMC solution with or without the injection of 25 mg/kg of ibuprofen and 3% CMC solution with the injection of 50 mg/kg of ibuprofen are effective and safe following abdominal surgery,
Aloe vera투여가 Cobalt-60 감마선 조사를 받은 마우스의 생존율과 조혈간세포에 미치는 영향
최민철,성재기,Choi Min-cheol,Sung Jai-Ki 한국임상수의학회 1990 한국임상수의학회지 Vol.7 No.2
The present study was carried out to investigate whether the aloe had a radioprotective effect in mice exposed to cobalt-60 gamma radiation or not. The survival ratio of mice for 30 days, hematopoiesis of blood-forming stem cells by spleen colony assay, chromosomal aberration frequency of bone marrow cells and histopathological findings of bone marrow were investigated. The survival ratios of aloe administered groups with concentration of 250, 500, 1,000 and 1,500mg for 3 days before irradiation and control group in cobalt-60 gamma irradiated mice(700rads whole body irradiation, dose rate of 50rads/min.) were 77.4, 79.3, 80.6, 90.0 and 53.1%, respectively. The survival ratios of pre-irradiation aloe administered groups were superior to those of post-irradiation aloe groups and control group. In spleen colony assay, Aloe vera administration before irradiation enhanced the recoveries of numbers of blood-forming stem cells of bone marrow of irradiated mice. There were decreased chromosomal aberrations of bone marrow cells at the first day after irradiation in aloe administered groups compared to that of control group. Histopathological findings in the bone marrow of irradiated mice were hypocellularity due to the depletion of myelocytes, abundant of fat vacuoles and these changes were weakened in aloe administered groups compared to that of control group.
최민철 ( Min Chul Choi ),이창진 ( Chang Jin Lee ),임영태 ( Young Tae Lim ) 한국운동역학회 2010 한국운동역학회지 Vol.20 No.4
This study was aimed at comparing selected joint angles at the golf address stance by categorizing three different body types. 43 elite male golfers were selected and 9 of them turned out to be the ectoderm while 24 of them to be the mesoderm. The remaining 10 subjects were the endoderm. The measurement was carried out at the address stance with the number 7 iron and the driver. The result showed that the angle of trunk flexion did not different among body types. The trunk tilting angle became more inclined to the right side, which confirmed the guidelines from most of golf lesson books, for bigger people since they tended to put more weight on the right foot. The angle of both knees showed similar but the right knee was bent more than the left knee. The target direction and body alignment faced more to the left side than the target spot because of the influence of open stance and natural aiming position. It seems that pelvis and knees turned a little bit more to the right side than the target direction in order to maintain the parallel. Overall, significant differences among body types were found at the trunk tilting angle and pelvis-target alignment and golf address configuration can be differentiate by these factors.
자궁내막암에 있어 수술 후 보조 방사선치료법과 수술 후 복합항암화학치료법의 임상 비교 연구
최민철 ( Min Chul Choi ),박지현 ( Ji Hyeon Park ),김수현 ( Su Hyun Kim ),전경훈 ( Kyung Hun Jun ),정상근 ( Sang Geun Jung ),나영정 ( Young Jeong Na ),이선영 ( Sun Young Lee ),이찬 ( Chan Lee ),황윤영 ( Yeun Young Hwang ),김승조 ( 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.11
목적: 자궁내막암의 수술 후 보조 치료로서 기존의 방사선치료와 paclitaxel과 platinum으로 이루어진 복합화학요법을 비교해보고자 하였다. 방법: 2000년 1월부터 2006년 12월까지 포천중문 의과대학 분당차병원 산부인과에서 조직학적으로 자궁내막암 진단을 받고 병기적 수술을 시행받은 105명을 대상으로 하였다. 이 중 조직학적으로 자궁내막양 선암 이외의 조직 양상을 보인 15명은 제외하였다. 수술 후 수술-병리적 결과에 따라 중등도 위험도 이상을 보인 58명을 대상으로 후향적 분석하였다. 이 중 36명은 항암치료를 받았고, 방사선치료는 24명을 대상으로 시행하였다. 항암치료의 항암제는 paclitaxel 175 mg/m2과 carboplatin AUC5 (또는 cisplatin 50 mg/m2)을 3주 간격으로 총 3회에서 6회에 걸쳐 병용 투여하였고, 방사선치료는 4,500~5,040 cGy가 조사되었다. 결과: 총 58명 대상자의 평균 추적기간은 40.3개월 (7~64개월)이었다. 5년 생존율은 항암치료군이 91.3%였고, 방사선치료군은 91.4%로 나타났으며 (P=0.646), 5년 무병 생존율은 항암치료군이 91.0%, 방사선치료군은 82.8%의 결과를 보였으나 통계적으로 유의한 차이는 없었다 (P=0.129). 항암치료의 가장 흔한 부작용은 혈액학적인 독성이었으나, 대부분 grade가 낮았고 보존적 치료로 조절되었다. 방사선치료군에서는 심각한 위장관계 독성을 5명 (20.8%)에서 보였고, 이 중 3명은 ileo-cecal bypass와 같은 수술적 중재를 요했으나 복통, 설사와 같은 증상은 수술 후에도 지속되었다. 결론: 자궁내막암에 있어 수술 후 보조 치료로서의 paclitaxel과 platinum의 복합화학요법은 유사한 치료 효과와 적은 독성의 측면에서 기존의 방사선치료를 대체할 수 있을 것으로 기대된다. 앞으로 더욱 많은 전향적인 대규모 연구가 필요할 것으로 사료된다. Objective: This study was performed to compare postoperative adjuvant paclitaxel and platinum (TC) chemotherapy and radiation therapy in women with uterine endometrial carcinoma. Methods: Total one hundred five patients were entered into this trial. Non-endometrioid histologic subtypes such as serous, clear cell and small cell types were excluded from the study because they have different biological potentials. Of 58 assessable patients, who were needed adjuvant treatment according to surgico-pathologic reports, after surgery, 34 were received TC chemotherapy and 24 were received radiation therapy. Chemotherapy consisted of paclitaxel 175 mg/m2 and carboplatin AUC 5 (or cisplatin 50 mg/m2) every 3 weeks for 3 or 6 cycles. Irradiation dosage was 4,500~5,040 cGy in 28 fractions. Results: In 58 evaluated patients, median follow-up time was 40.3 months (range 7~64 months). The 5-year overall survival and 5-year disease-free survival were 91.3% and 91.0% in 34 patients treated with TC chemotherapy, and 91.4% and 82.8% in 24 cases who treated with radiation therapy, however, there were no significant difference (P=0.646, P=0.129). The most common adverse effect of TC chemotherapy was hematologic toxicity, which was manageable conservatively. The serious gastrointestinal complication of radiotherapy was noted in 5 patients (20.8%), three of these patients were received another bowel surgery, such as ileo-cecal bypass, however, symptoms were persisted after surgery. Conclusions: These data suggest that postoperative adjuvant TC chemotherapy is a promising treatment which could be substituted for radiation therapy, with major activity and a acceptable toxicity profile for the treatment of uterine endometrial carcinoma.