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송창호 ( Chang Ho Song ),한진욱 ( Jin Wook Han ),최문경 ( Moon Kyung Choe ),임영훈 ( Young Hoon Lim ),김학주 ( Hak Ju Kim ) 대한면역약침학회 2014 대한면역약침학회지 Vol.3 No.2
Objectives : The aim of this study is bio-activity herbal medicine extracts specific prescription acne treatment. Methods : In this study, analyzed the amount of total sugar, reducing sugar, protein and flavonoid of herbal medicine. Screening of minimum inhibitory concentration of acnes strains. The anti-oxidative effect of herbal medicine was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl free radical scavenging activity. To investigate the anti-inflammatory effect, cyclooxygenase-2, tumor necrosis factor-a and interleukin-6 were measured. Results : The EE extract have higher antimicrobial activity. CE extracts showed relatively higher anti-oxidative effect. All extract have similar anti-inflammatory and Inhibiting cyclooxygenase-2. EE extract have higher inhibition of tumor necrosis factor-a and interleukin-6. Conclusions : EE extracts have anti-oxidant and anti-inflammatory effect, and inhibition effect of the cyclooxygenase-2, tumor necrosis factor-a and interleukin-6.
여드름 균의 항균 활성 및 생리활성 효과가 우수한 한약재 추출물의 탐색
송창호 ( Chang Ho Song ),임영훈 ( Young Hoon Lim ),최문경 ( Moon Kyung Choe ),김학주 ( Hak Ju Kim ) 대한면역약침학회 2014 대한면역약침학회지 Vol.3 No.2
Objectives : The aim of this study is screening of effective anti-microbial activity and bio-activity from herbal medicine. Methods : In this study, analyzed the amount of total sugar, reducing sugar, protein and flavonoid of herbal medicine. Screening of anti-microbial properties of acnes strains. The anti-oxidative effect of herbal medicine was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl free radical scavenging activity. To investigate the anti-inflammatory effect, cyclooxygenase-2, tumor necrosis factor-a and interleukin-6 were measured. Results : The anti-microbial activity of 11 herbal medicine extracts. 7 herbal medicine extracts showed relatively higher anti-oxidative and anti-inflammatory effect. Also showed Inhibiting cyclooxygenase-2, tumor necrosis factor-a and interleukin-6. Conclusions : Herbal medicine extracts have anti-oxidant and anti-inflammatory effect, and inhibition effect of the cyclooxygenase-2, tumor necrosis factor-a and interleukin-6.