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최교민,오지영 대한신경과학회 2021 대한신경과학회지 Vol.39 No.1
Peripheral neuropathy and pain are common adverse effects of chemotherapy, which incidence are rising significantly commensurate with extension of survival period in cancer patients. Chemotherapy-induced peripheral neuropathy is caused by most commonly used chemotherapeutic agents including platinum compounds, taxenes, proteasome inhibitors, thalidomide, and vinca alkaloids. Management of neuropathy and pain caused by chemotherapy is still challenging due to there is no proven therapies and preventive methods. The pain and its impact are becoming a main deterioration factor in quality of life and economic burden in our society. We review the mechanism, clinical characteristics, updated evidence of possible management of neuropathy and pain caused by traditional chemotherapeutic agents for contributing to the application of clinicians in their actual medical environment.
통증 치료에 있어서 신경과 의사의 역할 – 2020년 시행한 대한신경과학회의 설문조사를 기반으로
최교민,권오현,김상범,민양기,박기덕,서범천,서종근,손은희,오건세,오지영,이광수,이동국,정종필,조수진,조수현,한영수,주인수 대한신경과학회 2021 대한신경과학회지 Vol.39 No.3
Background: Pain is one of the most common chief complaints in neurological field. Authors try to inform the current situation of pain medicine in neurological practice and present an effective method for pain-related education during neurology residency and for practicing neurologists. Methods: A survey was conducted from November 16 to November 27, 2020 for members of the Korean Neurological Association, and the results were analyzed. Results: About two-thirds of neurologists replied that more than 25% of their patients were suffered from diverse pain including headache, spine pain or neuropathic pain. Despite many patients are visiting to neurologist for pain treatment, most neurologists are aware that they have not received sufficient practical pain education in the past and present. Therefore, they want more educational opportunities in pain medicine including interventional pain management and physical and pharmacologic therapies for more effective treatment. Conclusions: More follow-up studies on pain treatment and education should be conducted. It is also essential that the members of the society continue to interest and participate in the change of the pain education program.
최교민,오지영 대한근전도전기진단의학회 2021 대한근전도 전기진단의학회지 Vol.23 No.3
Transthyretin amyloidosis (aTTR) is a life-threatening type of systemic amyloidosis that has been associated with autosomal dominant mutations in the transthyretin gene. In this case series, we reviewed 3 patients initially treated for acquired demyelinating neuropathy that was later confirmed by pathologic testing and genetic analysis as aTTR. These patients had systemic symptoms and family records of sudden deaths that could not be explained by acquired demyelinating neuropathy. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a treatable neuropathy; however, 20% to 33% of CIDP patients remain refractory to conventional immunotherapy, and incorrect diagnoses might be the cause of this therapeutic failure. This case series revealed that the electrophysiological findings of aTTR could resemble the findings of demyelinating neuropathy.
Kriging 분석법을 이용한 지하철 터널 미세먼지 추정
이용일,정원석,최교민,김태성,박덕신 한국냄새환경학회 2016 실내환경 및 냄새 학회지 Vol.15 No.2
This study measured the particulate matter (PM) in a subway tunnel using a dust spectrometer and estimated the PM10 and PM2.5 using a Kriging method. For the hourly measurement, a probe was attached inside the cabin and put through the window to collect data from the outside. The Kriging method is a spatial analysis method, and time and spatial data were applied in the subway tunnel along with a PM concentration map. The result of the measurement shows that PM10 is 31.9~271.3 μg/m3 and PM2.5 is 30.9~209.5 μg/m3. In addition, The pollutant map shows that some sections have a higher concentration than other sections because of the depth and curvature of tunnel and traffic volume on the section and local construction. Also, the results show that differences concentration at different times of sampling could be distinguished. The highest concentration was found at 3 pm while the lowest was at 12 pm. We expect to use the pollutant map in planning air quality improvements for the tunnel.