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정보 공개에 따른 지역별 항생제 처방률 변이에 영향을 미치는 요인 - 전국 시군구 의원을 중심으로 -
천유진,김창엽 한국보건행정학회 2012 보건행정학회지 Vol.22 No.3
Objectives : This study examined the factors influencing variation by local areas of antibiotics prescription rate in upper respiratory infections (URI) according to the public reporting. Methods : We used the National Health Insurance Claims Data which the clinics claimed for URI (Korean Standard Classification of Disease, J00 ~ J06) in ambulatory care. The period of analysis was from the first quarter (from January to March) of 2005 to the first quarter of 2007. The number of samples was total 242 local areas that included all clinics (N = 7,942), which prescribed antibiotics for URI in ambulatory care. Results : None of the demographic and socioeconomic characteristic indicators was statistically significant. Among the provider factors, An increase in number of doctors and the average annual antibiotics prescription rate (from 2003 to 2004) for URI by local area were significantly related to an increase of antibiotics prescription rate according to the public reporting. And an increase in number of pediatric clinics, the proportion of clinics less than 5 years since has opened and the average annual fluctuation of antibiotics prescription rate (from 2003 to 2005) were significantly related to a decrease in antibiotics prescription rate by local area according to the disclosure of information. Conclusions : According to the public reporting, the antibiotics prescription rate in clinics had decreased sharply. However, the reduction of antibiotic prescription rate varied in different local areas. The factors influencing variation by local areas in antibiotics prescription rate can be used for establishing effective strategies to reduce variation by region in antibiotics prescription rate.
천유진,성수환,이인범,이지태,유창규,허준행,조성종,김용언,김재우,김종기 제어로봇시스템학회 2011 제어로봇시스템학회 국내학술대회 논문집 Vol.2011 No.5
A SOFC(Solid-Oxide-Fuel-Cell) emulator composed of real-time SOFC system model, power supply, power board and sensor-actuator board is developed. It can be very useful for developing control and operation logics and performing various tests to understand the dynamic characteristics of a SOFC system without operating real SOFC systems. Control logics for the SOFC system is developed for case study and its performances are demonstrated by applying them to the SOFC emulator.
천유진,정희철,박형순,박지수,라선영,최혜진,이재훈,전태주 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.7
Purpose: This study aimed to determine the prognostic value of new quantitative parameters of 18F-fluorodeoxyglucose positronemission tomography/computed tomography (18F-FDG PET/CT), including metabolic tumor volume (MTV), in patients with locallyadvanced and metastatic gallbladder cancer (GBC). Materials and Methods: In total, 83 patients initially diagnosed with locally advanced and metastatic GBC and who underwent18F-FDG PET/CT at the time of initial diagnosis were retrospectively reviewed. The metabolic volume-based PET parameters of primarytumors and metastatic lesions were measured, including maximum and average standardized uptake values (SUV), MTV,and total lesion glycolysis. An overall survival (OS) analysis was performed using the Kaplan-Meier method with PET and clinicalparameters. A Cox proportional hazards regression analysis was performed to determine independent prognostic factors. Results: In univariate analysis, pathologic differentiation (p<0.001), performance status (PS; p=0.003), C-reactive protein (CRP)level (p=0.009), and PET-related SUVmt max (the highest SUV among the metastatic lesions) (p=0.040) and MTVtotal (the sum of theMTVs of both the primary and metastatic lesions) (p=0.031), were significant for OS. In multivariate analysis, MTVtotal (hazard ratio:2.07; 95% confidence interval: 1.23–3.48; p=0.006) remained significant for the prediction of OS, as did differentiation(p=0.001), PS (p=0.001), and CRP (p=0.039). Conclusion: In locally advanced and metastatic GBC, volume-based PET/CT parameters of the total tumor burden of malignancy,such as MTVtotal, were found to be useful for the identification of patients with poor prognosis.
간암 환자에서 간동맥화학색전술 후 생긴 기관지담도 누공을 내시경으로 치료한 1예
유진,이태윤,천영국,심찬섭 대한췌담도학회 2019 대한췌담도학회지 Vol.24 No.1
기관지담관루는 간세포암 환자에서 여러 차례의 간동맥화학색전술 후 드물게 일어날 수 있는 합병증이다. 본 증례의 78세 남자 환자는 11차례의 간동맥화학색전술을 시행받고 5개월 후 발생한 기침과 담즙성 객담으로 내원하였다. MRCP상 기관지담관루는 오른쪽 간내담관(B7)과 기관지 사이에 위치하였다. ERCP를 시도하였으나 심한 간문부의 폐쇄로 기관지담관루가 위치한 우측 간내담관을 조영할 수 없었고, 이후 PTBD를 시행하여 매일 30-50 mL의 담즙이 배출되면서 객담 배출은 멈추었다. PTBD 배액관을 유지하고 2개월 동안 관찰하였으나 누공이 지속되어 두 번째 ERCP를 시행하여 기관지담관루 부위에 플라스틱 스텐트를 유치하였다. 1주 후 PTBD를 통하여 시행한 담도조영술에서 기관지담관루는 소실되었다. 환자는 스텐트 시술 이후에 더 이상 객담을 배출하지 않았고 2개월 이후에 시행한 ERCP에서도 기관지담관루가 관찰되지 않았다. Bronchobiliary fistula (BBF) is a rare complication after transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma. We present a case of BBF that developed 5 months after 11 TACE procedures in a 78-year-old male patient with a 3-month history of a persistent cough and yellowish sputum. BBF was found between the bronchus and the right intrahepatic bile duct (B7) by magnetic resonance cholangiopancreatography. On the initial endoscopic retrograde cholangiopancreatography (ERCP), we failed to approach to the BBF due to severe hilar obstruction. Percutaneous transhepatic biliary drainage (PTBD) was performed, and 30-50 mL of bile was drained daily. But the BBF was not resolved until 2 months after PTBD. The patient was treated by placement of a plastic stent to the BBF site during the second ERCP. BBF was resolved 7 days after ERCP on the PTBD tubogram. The patient remained asymptomatic after the stent placement, and there was no recurrence at the 2-month follow-up ERCP.
증례 : 혈액종양 ; 혈액투석 환자에서 발생한 카포시육종의 Pazopanib 치료 증례
천유진 ( You Jin Chun ),최아란 ( Ah Ran Choi ),양서연 ( Seo Yeon Yang ),김효은 ( Hyo Eun Kim ),조장호 ( Jang Ho Cho ),임재윤 ( Jae Yun Lim ),조재용 ( Jae Yong Cho ) 대한내과학회 2015 대한내과학회지 Vol.89 No.1
현재까지 우리나라에서는 본 증례를 포함해 아주 적은 수의 혈액투석 환자에서의 카포시육종이 보고되었으며, 특히 pazopanib을 첫 치료제로 선택한 경우는 보고된 바가 없다. 저자는 림프절병증을 동반한 카포시육종에서 pazopanib 복용 후 피부 병변 크기 감소 및 통증 완화의 치료 효과 있음을 경험하여 보고하고자 한다. Kaposi’s sarcoma (KS) is an unusual multifocal neoplastic angioproliferative disorder. We herein report a case of classic KS that occurred in a patient receiving hemodialysis for 7 years. The patient had a history of chronic renal failure due to glomerulonephritis for 20 years. Multiple reddened violaceous patches, plaques, and nodules were found on the right knee. Biopsy revealed positivity for human herpesvirus 8 (KS-associated herpesvirus) consistent with KS. Pazopanib, a multitarget tyrosine kinase inhibitor, is an effective agent for treatment of advanced soft tissue sarcoma. The patient received pazopanib for 6 months investigate its effects on KS. The skin lesions and painful symptoms showed improvement. Further studies are required to determine the mechanism underlying the anticancer action of pazopanib and the pathogenesis of KS. (Korean J Med 2015;89:113-116)
도자기의 특성 분류를 위한 휴대용 X-선 형광분석의 필터 선정과 측정법 검토
천유진 ( Yoo Jin Chun ),김규호 ( Gyu Ho Kim ) 공주대학교 문화재보존과학연구소 2021 문화재과학기술 Vol.16 No.1
본 연구는 휴대용 X-선 형광분석기를 활용하여 도자기 유약의 주요 성분과 특성 분류에 가장 적합한 측정 시간과 필터 조건을 검토하고, 이를 기준하여 도자기의 기종별 특성 분류에 따른 측정 방법을 제시해 보고자 한다. 측정 원소에 대한 검출 강도(Intensity; cps/㎂)와 정밀도를 비교하였다. 연구 결과, 도자기 유약의 주요 성분과 특성 분류에 가장 적합한 시간은 60초, 필터 조건은 No filter 조건임이 확인된다. 이상의 측정 조건을 기초로 점토 물질의 분류 인자로 알려진 Rb 분율과 Sr 분율을 도식화하고 주성분분석을 이용하여 종류에 따른 도자기의 특성을 평가한 결과에서 Sr 분율과 주성분분석에서 종류별로 구분되는 것으로 나타난다. 이를 통하여 휴대용 X-선 형광분석을 통해 도자기의 기종 및 특성에 따른 분류 기준을 제시할 수 있다. This study examines the measurement time and filter conditions most suitable for classifying the main components and characteristics of ceramic glaze using portable X-ray fluorescence analysis, and based on this, suggests a measurement method according to the characteristic classification of each type of ceramic. The detection intensity(Intensity; cps/μA) and precision of the measuring element were compared. As a result of the study, it is confirmed that the most suitable time for classifying the main ingredients and characteristics of ceramic glaze is 60 seconds, and the filter condition is the No filter condition. Based on the above measurement drafts, the Rb fraction and Sr fraction known as classification factors of clay materials were schematized. In addition, the characteristics of ceramics according to the type were evaluated using principal component analysis. As a result, it appears to be classified by type in the Sr fraction and principal component analysis. Through this, it is possible to present classification criteria according to the types and characteristics of ceramics through portable X-ray fluorescence analysis.