리튬이차전지용 Si-Ti-Fe 합금 음극소재의 미세구조 분석

채정은 ( Jeong Eun Chae ),양준모 ( Jun Mo Yang ),박경진 ( Kyung Jin Park ),유정호 ( Jung Ho Yoo ),박윤창 ( Yun Chang Park ),성민석 ( Min Suk Sung ),유현종 ( Hyun Jong Yu ),김성수 ( Sung Soo Kim ) 대한금속·재료학회 2013 대한금속·재료학회지 Vol.51 No.6

흉부 X-ray 검사 시 DEI 값에 따른 적정 관전압에 관한 고찰

채정현(Jeong-hyun, Chae),심지나(Ji-na, Sim),정지상(Ji-sang, Jung),한영수(Yung-soo, Han),진덕은(Duk-eun, Jin),강성호(Sung-ho, Kang),임재식(Jae-sik, Lim) 대한영상의학기술학회 2014 대한영상의학기술학회 논문지 Vol.2014 No.1

목 적 : 흉부 X-ray 검사 시, DR 시스템에 적절한 유효 Detector Exposure Index (DEI) 범위 내의 영상의 Dose Area Product (DAP)값과 유효선량을 비교함으로써, high kVp 사용의 적합성을 영상의 퀄리티나 환자선량 측면에서 평가하기 위함에 있다. 대상 및 방법 : GE definium 8000을 사용하여 흉부팬텀을 이용한 Chest PA 검사를 재현하였다. kVp range는 60~130 kVp로 정하였다. mAs range는 앞의 정한 kVp에 따라 Auto Exposure Control (AEC) 시스템에 의거하여 60kVp에서는 40mAs, 130kVp에서는 2.5mAs로 정하였고 mAs range는 2.5mAs에서, 3.2mAs, 4.0mAs, 5.0mAs, 6.3mAs, 8.0mAs, 10mAs, 12.5mAs, 16mAs, 20mAs, 25mAs, 32mAs, 40mAs로 설정하였다. 위의 kVp 조건에 따라, 각각의 mAs로 총 104번 을 exposure한 뒤, 세브란스 선량관리 시스템으로 전송된 영상의 DEI와 DAP를 획득할 수 있었다. 획득한 영상을 유효한 DEI 범위의 영상들(0.2-0.6 : 정상군)과 DEI 0.2 이하, DEI 0,6 이상인 영상들 을 각각 분류하고 DAP을 이용하여 a PC-Based Monte Carlo Program 2.0 (PCXMC)을 통해 유효 선량을 계산하였다. 각각의 측정한 데이터를 DEI기준, DAP기준, 유효선량의 기준으로 분류한 후, DR 시스템에서 Chest PA 검사 시 적절한 kVp 범위를 분석하였다. 각 그룹의 유의성은 SPSS(version 12.0, SPSS Inc Chicago, IL, USA) 통계 패키지 프로그램을 사용하여 kruskal-wallis test와 사후검정으로 mann -whitney test를 시행하여 검증 하였으며 검증에 사용된 신뢰구 간은 95 %이다.    결 과 : 위의 실험을 통해 얻은 유효한 DEI 범위(0.2-0.6)에 포함된 영상의 평균 kVp는 75.29 kVp 이고 평균  mAs는 8.58 mAs, 평균 DAP는 1.73 mGy·cm², 유효선량은 0.018 mSv 이었다. 유효선 량별로 수집한 군에서 최저의 유효선량인 0.011449 mSv가 측정된 조건은 70kV, 5mAs, DAP 1.06mGy·cm²,이었다. 실측값 DAP에 따른 군에서는 최저 DAP 인 0.885 mGy·cm²에서 조건은 90kV, 2.5mAs, 0.013mSv이 측정되었다. 유의성 검증 결과, 유효 DEI 범위 내의 유효선량에서 유의한 차 이(p<0.05)가 있었고, 전체 DEI 그룹에서 대해서는 0.2 이하 범위와 0.2이상 0.6 이하의 범위, 0.6이상의 범위의 유효선량과 DAP에서 모두 유의한 차이가 있었다.(p<0.05)  결 론 : 각각의 DEI, DAP, 유효선량 기준으로 분류된 데이터를 통해 현재 사용되고 있는 흉부 검사 시 high kVP기법은 환자 피폭적인 측면과 영상의 퀄리티적인 측면에서 재고할 필요성이 있다고 사료된다. Purp os e : This study is to evaluate the suitability of the use of high kVp technique for Chest PA examination in DR system by comparing with Dose Area Product and effective dose of chest images in efficient Detector Exposure Index(DEI) range.    Materials and Methods :  We set up situation of Chest PA examination with GE definium 8000. kVp range is 60~130 kVp. Range of mAs is 40 mAs at 60kVp, 2.5mAs at 130kVp  through Auto Exposure Control system(AEC) in accordance with kVp range we set, then we set up mAs range from 2.5mAs, 3.2mAs, 4.0mAs, 5.0mAs, 6.3mAs, 8.0mAs, 10mAs, 12.5mAs, 16mAs, 20mAs, 25mAs, 32mAs to 40mAs. We exposured 104 times as the kVp condition we set, then all images are sent to the Severance Dose management system which we can acquire DEI and DAP data. We classified acquired images into several DEI groups–under 0.2, between 0.2 and 0.6, over 0.6, then calculated Effective Dose with DAP by using a PC-Based Monte Carlo Program 2.0(PCXMC). After classifying acquired data into 3 groups according to DEI, DAP and effective dose, we analyzed suitable kVp range for Chest PA examination in DR system. SPSS(version 12.0, SPSS Inc Chicago, IL, USA) is used for statistical significance, which is Kruskal-Wallis test and Mann-Whitney test to each group. Confidence interval is 95%.  Res ult : Average kVp of image in efficient DEI range from the experiment is 75.29 kVp, mAs is 8.58 mAs, DAP is 1.73 mGy·cm² and effective dose is 0.018 mSv. The condition which 0.011449 mSv is acquired as the lowest effective dose is 70 kVp, 5mAs, DAP 1.06mGy·cm² in groups classified with effective dose. Another condition which 0.885mGy·cm² is acquired as the lowest DAP is 90kV, 2.5mAs, and Its effective dose is 0.013mSv. As a result of statistic significance test, there is significance difference in effective dose of the efficient DEI range group(p<0.05) and significance difference is found in whole DEI groups of under 0.2, between 0.2 and 0.6, over 0.6(p<0.05)  Conc lus ion : According to each classified data with DEI, DAP, Effective dose, high kVp technique for Chest PA examination which is currently used is need to be reconsidered in patient exposure and image quality.

긍정심리학의 생물학적 배경

강은호(Eun-Ho Kang),박주언(Joo-Eon Park),채정호(Jeong-Ho Chae),박영민(Young Min Park),최삼욱(Sam-Wook Choi) 대한스트레스학회 2008 스트레스硏究 Vol.16 No.3

Most modern researches have focused on the underlying biological mechanisms as the basis of various psychopathology such as psychosis, depression, anxiety, etc. However, little is known about the biological basis of positive psychology. Recent developments in biological and neuroscientific techniques enable us to speculate that there are also biological basis in the field of positive psychology. The author introduces some important researches on the biological basis of positive psychology.

결핵성 흉막염 치료 후 잔류된 만성 흉막삼출에서 발생한 가성유미흉

박은경 ( Eun Kyoung Park ),정숙희 ( Sook Hee Chung ),배준호 ( June Ho Bae ),류상열 ( Sang Ryol Ryu ),이재형 ( Jae Hyung Lee ),김상훈 ( Sang Hoon Kim ),조영욱 ( Young Uk Cho ),채정돈 ( Jeong Don Chae ),이병훈 ( Byoung Hoon Lee ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.5

A pseudochylothorax, a chyliform pleural effusion, is a rare disease of pleural effusion that contains cholesterol crystals or high lipid content that is not the result of a disrupted thoracic duct. Most of the cases were found in patients with long-standing pleural effusion due to chronic inflammatory disease, such as old tuberculous pleurisy or chronic rheumatoid pleurisy. We experienced a case of pseudochylothorax in a 74-year-old man, who was being treated for pulmonary tuberculosis and pleurisy 10 years ago. The diagnosis was confirmed on pathological study of the pleural effusion, which contained cholesterol crystals having a diagnostic rhomboid appearance.

MMPI-2와 Personality Assessment Inventory 타당도 척도를 이용한 외상후 스트레스 장애 환자의 증상과장 평가

공성회,채정호,이종훈,한상우,박은진,최경숙,대한불안의학회 PTSD 연구회,Kong, Sung-Whoi,Chae, Jeong-Ho,Lee, Jong-Hun,Hahn, Sang-Woo,Park, Eun-Jin,Choi, Kyeong-Sook 대한불안의학회 2012 대한불안의학회지 Vol.8 No.1

Objective : We investigated whether Posttraumatic stress disorder patients have a higher tendency to exaggerate the extent of their psychological symptoms compared to other psychiatric patients. Methods : Medical records of patients, who had received psychiatric treatment at four university hospitals in Korea between January 2009 and December 2010, were retrospectively reviewed. We compared a group of 37 patients diagnosed with PTSD, and another group of 41 patients diagnosed with neurotic, stress-related and somatoform disorders according to the ICD-10. To compare the extent of malingering in the two groups, we compared the validity scales of MMPI-2 and Personality Assessment Inventory. We determined the number of participants in both groups feigning their responses by using various cutoff scores of the validity indicators. Results : The PTSD group showed significantly higher scores on the F (p=0.001), F (B)(p=0.000), F (P)(p=0.030), F-K (p=0.003) scale of the MMPI-2 compared to the other group of psychiatric patients. The PTSD group had a significantly higher NIM score (p=0.001) but a lower PIM score (p=0.020) of the PAI compared to the other group of psychiatric patients. Using the cutoff scores, the PTSD group showed a significantly higher number of patients who feigned responses compared to the other group ($Fb{\geq}75$ (p=0.010), $F-K{\geq}1$ (p=0.005), $F-K{\geq}10$ (p=0.011) from the MMPI-2, and $NIM{\geq}80$ (p=0.001) from the PAI). Conclusion : These results suggest that PTSD patients have a tendency to exaggerate their symptom. This group of patients overreported the severity of their condition during standardized personality assessment that included the MMPI-2 or PAI compared to patients diagnosed with other psychiatric disorders. Additional research is required to determine the factors influencing symptom exaggeration in PTSD.

전구체의 물성에 따른 리튬 2차전지용 Li(Ni_0.5Co_0.2Mn_0.3)O₂의 전기화학적 특성 변화

강동현,채정은,김성수,Kang, Donghyun,Arailym, Nurpeissova,Chae, Jeong Eun,Kim, Sung-Soo 한국전기화학회 2013 한국전기화학회지 Vol.16 No.4

리튬2차전지용 양극소재인 $Li(Ni_{0.5}Co_{0.2}Mn_{0.3})O_2$를 공침법을 이용해 $Ni_{0.5}Co_{0.2}Mn_{0.3}(OH)_2$ 전구체로부터 합성하였고, 공침조건을 조절하여 전구체의 1차 입자 형상을 Flake형상과 Needle형상으로 제어하였다. 동일한 공정으로 리튬과 혼합하고 열처리하여, 입도, 탭밀도, 화학적 성분 등이 동일한 분체물성의 양극 소재를 합성하였다. 전구체의 1차입자 형상에 따른 $Li(Ni_{0.5}Co_{0.2}Mn_{0.3})O_2$의 전기화학적 특성을 평가하고, 이 특성의 변화를 SEM, XRD, EELS로 이용하여 분석하여 연관성을 고찰하였다. Needle형상 전구체로 합성한 $Li(Ni_{0.5}Co_{0.2}Mn_{0.3})O_2$ 양극의 1차입자는 Flake형상 전구체로 합성한 경우보다 작고, EELS결과로는 입자표면의 Li농도가 내부보다 상대적으로 높았다. 전기화학적인 수명과 출력특성에서 Needle형상 전구체로 합성한 양극이 Flake형상 전구체의 경우보다 우수한 특성을 보였는데, 임피던스 측정으로부터 낮은 전하이동저항에 연관되어 있을 것으로 생각된다. The one of the cathode material, $Li(Ni_{0.5}Co_{0.2}Mn_{0.3})O_2$, was synthesized by the precursor, $Ni_{0.5}Co_{0.2}Mn_{0.3}(OH)_2$, from the co-precipitation method and the morphologies of the primary particle of precursors were flake and needle-shape by controlling the precipitation parameters. Identical powder properties, such as particle size, tap density, chemical composition, were obtained by same process of lithiation and heat-treatment. The relation between electrochemical performances of $Li(Ni_{0.5}Co_{0.2}Mn_{0.3})O_2$ and the primary particle morphology of precursors was analyzed by SEM, XRD and EELS. In the $Li(Ni_{0.5}Co_{0.2}Mn_{0.3})O_2$ cathode from the needle-shape precursor, the primary particle size was smaller than that from flake-shape precursor and high Li concentration at grain edge comparing grain center. The cycle and rate performances of the cathode from needle-shape precursor shows superior to those from flake-shape precursor, which might be attributed to low charge-transfer resistance by impedance measurement.

Saccharomyces Cerevisiae 효모 추출물 SCP-20의 스트레스 반응, 불안 및 우울에 대한 효과 : 이중 맹검 위약 통제 연구

이하민,정영은,채정호,Lee, Ha-Min,Jung, Young-Eun,Chae, Jeong-Ho 대한불안의학회 2009 대한불안의학회지 Vol.5 No.1

Saccharomyces cerevisiae 효모추출물인 SCP-20은 동물실험에서 항스트레스, 항불안 및 항우울 효과를 보인 바 있다. 본 연구는 정상인을 대상으로 위약통제 이중맹검 연구를 시행하여 SCP-20의 효과를 검증하였다. 선별과정을 거치고 충분한 순응도를 보인 61명의 자원자의 정보가 최종 분석에 사용되었다. 이들은 4주간 SCP-20이 70% 함유된 캡슐, SCP-20 99.5% 함유 캡슐 그리고 위약캡슐 중 한가지를 하루 4회 복용하였다. 4주 뒤 SCP-20 복용군은 위약군에 비해 SRI, BAI 점수에서 유의한 개선을 보였으나,BDI 점수변화는 군간 유의미한 차이가 없었고 집단별 사후검정에서 SCP99.5군만이 복용 전후 유의미한 BDI 점수감소를 보였다. HRV는 유의미한 변화를 보이지 않았다. 부작용은 관찰되지 않았다. SCP-20은 정상인에게 투여하였을 때 위약에 비해 유의하게 항스트레스, 항불안 효과를 보이나 항우울 효과는 명확하지 않았으며, 부작용은 보이지 않았다. 향후 SCP-20의 항우울기능 추가 검증 및 환자군을 대상으로 한 대규모, 장기적 연구가 필요하다. Objective : SCP-20, a yeast hydrolysate from Saccharomyces cerevisiae, has exhibited anti-stress, anti-anxiety, and antidepressant effects in animal studies. The objective of this study was to test the effects of SCP-20 on healthy controls and to assess its effects on stress response, depression and, anxiety. Methods : Sixty-one healthy volunteers (30 male, 31 female) were recruited and screened for significant psychiatric and medical conditions. Baseline measures of stress, anxiety, and depression were taken using questionnaires such as the Stress Response Inventory (SRI), Beck's Anxiety Inventory (BAI), Beck's Depression Inventory (BDI), and the physiological measure of heart rate variability (HRV). Each subject was assigned randomly to a group taking capsules containing either 70% SCP-20 (i.e. the SCP70 group), 99.5% SCP-20 (i.e. the SCP99.5 group), or a placebo. Follow up measures were taken at week 4. Results : Subjects taking SCP-20 showed significant improvement in SRI and BAI scores compared to those taking placebo. For BDI scores, there was no significant difference between groups. No significant adverse effects were reported. Conclusions : This study suggests that SCP-20 is effective in alleviating stress and anxiety symptoms in healthy individuals, and has little or no side effects. However, the role of of SCP-20 in alleviating depression needs further clarification. Studiess examining its effects in psychiatric populations are needed to establish its role in alternative medicine.

태안 원유 유출 사고 피해자에게 제공한 숲 환경을 이용한 긍정심리학 기반의 다중 심리적 중재의 효과

정영은(Young-Eun Jung),박민선(Min-Sun Park),박주언(Joo-Eon Park),우종민(Jong-Min Woo),최수찬(Soo Chan Choi),채정호(Jeong-Ho Chae) 대한스트레스학회 2010 스트레스硏究 Vol.18 No.3

원유 유출 사고는 태안 주민들에게 극심한 정신적 고통을 초래한 외상적 사건이다. 본 연구는 태안 피해 주민을 대상으로 스트레스 반응과 외상 후 증상을 평가하고, 숲 환경을 이용한 긍정 심리학 배경의 중재 프로그램의 효과를 알아보고자 하였다. 37명의 태안 주민이 강원도에 위치한 산림원에서 시행된 3일간의 프로그램에 자발적으로 참여하였으며, 외상 관련 증상과 스트레스 반응을 같이 평가 받았다. 연구 결과, 태안 피해 주민은 많은 수가 심각한 외상 후 스트레스 장애 증상을 겪고 있으며, 프로그램 참여가 스트레스 반응 및 생리적 변화에 있어 긍정적인 효과가 있는 것으로 조사되었다. The oil spill around Taean peninsula has traumatized and has dawned such psychological sufferings onto the inhabitants. The purpose of this research is to identify the symptoms of posttraumatic stress disorder (PTSD) among Taean inhabitants and investigate the effects of multiple psychological interventions that took place in the forest environments. Thirty seven Taean inhabitants voluntarily participated in the program which was held at an arboretum in Kangwon-do for 3 days. The program consisted of multiple psychological interventions based on positive psychology. We assessed the participants using self-reporting questionnaires consisting of symptoms related to trauma and stress-related reactions. As a results, the majority of Taean inhabitants participating in the program had serious PTSD symptoms. The psychological interventions based on positive psychology in the forest environments is effective in alleviating stress reactions and stabilizing physiologic response. (Korean J Str Res 2010;18:181∼189)

약물에 노출되지 않은 공황장애 환자들에서 인지행동치료 후 뇌혈류 변화에 대한 예비연구

김정범,신영아,채정호,장은진,류설영,원경숙,전석길,정용안,Kim, Jung-Bum,Shin, Young-Ah,Chae, Jeong-Ho,Chang, Eun-Jin,Ryu, Seol-Young,Won, Kyoung-Sook,Zeon, Seok-Kil,Chung, Yong-An 대한불안의학회 2008 대한불안의학회지 Vol.4 No.2

Objective : Although cognitive-behavior therapy (CBT) is effective in patients with panic disorder, its the-rapeutic mechanism of action in the brain remains unclear. This study was performed to investigate regional blood flow changes associated with successful completion of CBT in drug-naive patients with panic disorder. Method : The regional blood flow in 4 patients with panic disorder was compared to that in 11 healthy controls before and after a 12-week group CBT using $^{99m}Tc$-ECD SPECT imaging. Psychopathology was assessed using Panic Disorder Severity Scale. Data were analyzed using software for statistical parametric mapping (SPM2). Results : Before CBT, significantly decreased blood flow was found in the parietal and occipital area in panic patients than normal volunteers. In all the patients who showed remission after CBT, increased blood flow was detected in the right cingulate gyrus, left lingual gyrus, and left superior parietal lobule, whereas decreased blood flow was seen in the left inferior temporal gyrus. Conclusion : These results suggested that CBT is effective for panic disorder and change the activity of cingulate gyrus and left temporal gyrus, a part of the brain areas associated with fear in panic disorder.

소방 공무원에서 간접 외상이 정신 건강에 미치는 영향

백준혁,정영은,채정미,명준표,임현우,채정호,Baik, Jun-Hyuck,Jung, Young-Eun,Chae, Jung-Mi,Myong, Jun-Pyo,Yim, Hyeon-Woo,Cha, Jeong-Ho 대한불안의학회 2010 대한불안의학회지 Vol.6 No.1

Objectives : Indirect contact with trauma may occur when a person empathically listens to detailed descriptions, exposing the person to intense emotional pain from trauma victims. Although less severe than direct trauma, indirectly traumatized persons may experience the same fear, rage, and despair as direct trauma victims. This phenomenon has been variously termed vicarious trauma, traumatic countertransference, burnout, compassion fatigue, and secondary traumatic stress. Using a psychiatric symptoms questionnaires, this study investigated the effects of indirect exposure to co-worker's trauma on the mental health of firefighters who had not directly experienced traumatic events in the previous year. Methods : We administered self-report questionnaires, such as the Impact of Event Scale-Revised (IESR) and Alcohol Use Disorder Identification Test (AUDIT), to firefighters working at two fire stations in a metropolitan city. We analyzed 188 of 232 collected surveys, after excluding falsely entered data (28 cases) and questionnaires by directly-traumatized victims (16 cases). Results : Alcohol consumption and posttraumatic stress disorder (PTSD) symptoms, as determined by the AUDIT and IES-R, were significantly higher in the indirectly-traumatized group. The ratio of high-risk members scoring higher than 23 in IES-R was larger in the indirectly traumatized group, although this was not statistically significant. Conclusion : Alcohol consumption was significantly higher in the indirectly traumatized group. This group also included more members at high risk for PTSD. Further research, with a larger group of indirectly traumatized firefighters and ongoing investigation of PTSD development and other psychiatric symptoms, is needed.