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Multifunctional Heteroscaled Hydrogel Integrated with Dispersible Hybrid Nanofibers
Chaenyung Cha(차채녕) 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
Hydrogels are widely used as scaffolds for cell and tissue culture applications. However, it is challenging to culture cells in 3D hydrogels at higher mechanical stiffness, as diminished permeability leads to limited diffusion of nutrients and available space for sufficient cellular activities. Herein, a novel strategy of incorporating short, aqueous-dispersible nanofibers into hydrogel is presented. Infusing nanofibers into hydrogel without changing the crosslinking density allowed the control of hydrogel mechanics, while limiting the change in permeability. Furthermore, nanofibers with a conductive polymer helped impart electrical conductivity to the hydrogel, allowing more efficient propagation of externally-applied electrical signals through the hydrogels. The resulting multifunctional nanofiber-infused hydrogels, with controllable mechanical and electrical properties, were utilized as a 3D cell culture platform to study the effects of various microenvironmental conditions.
고분자와 세라믹의 만남 : 고분자를 통한 세라믹 3D 프린팅 기술의 발전
차채녕(Chaenyung Cha) 한국세라믹학회 2020 세라미스트 Vol.23 No.1
The recent advances and popularity of 3D printing technology have centered around building polymerbased ‘plastic’ materials, due to their low cost, simple and efficient processing, and mechanical toughness. For this reason, printable polymers are actively recruited to create ‘ceramic resins’ that allow more facile fabrication of ceramic materials that are difficult to print directly. Herein, a brief history and the current state of ceramic 3D printing technology aided by polymer is summarized. In addition, a new ceramic 3D printing technology using polymer-derived ceramics (PDC) is also introduced.