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Imaging Features of Hepatic Adenoma in a Dog with Atypical Computed Tomographic Findings
진한솔,천병규,이가현,박승조,이주환,최지혜 한국임상수의학회 2018 한국임상수의학회지 Vol.35 No.2
Computed tomography (CT) findings of hepatic adenoma in veterinary medicine are variable and unlikein human medicine, not defined clearly. A 12-year-old neutered male Shih Tzu presented after a seizure, with weightloss, salivation, and cachexia. An abdominal mass was identified on radiography, and ultrasonographic images showeda mixed echo pattern with marked vascularity. CT showed that the mass originated from caudate lobe, washeterogeneously hypoattenuated compared with the hepatic parenchyma, and had irregular margins. Contrast enhancedCT showed that the mass enhanced like the surrounding liver parenchyma. However, it contained unenhanced areasand enhanced vessels were observed in the arterial phase at the periphery of the mass. The margins of mass weremore enhanced in the venous phase than the arterial phase and the hypoattenuating regions within the mass werenot enhanced. Greater enhancing in the venous phase is seen with adenomas; however, the heterogeneous enhancementpattern, especially the marginal vascular enhancement and internal hypoattenuating regions, is seen with malignancy. Although this is a single case of hepatic adenoma, the atypical enhanced pattern of this case can provide usefulinformation to predict the malignancy of primary liver tumor.
한방치료를 통한 성인 전신성 아토피 피부염 치험 1례 - 五苓散 사용 효과를 중점으로
진한솔,윤화정,고우신 대한한방안이비인후피부과학회 2019 한방안이비인후피부과학회지 Vol.32 No.4
Objetives : The purpose of this study is to report the effect of Oryeong-san on adult whole-body atopic dermatitis. Methods : We treated a 21-year-old male patient who have adult whole-body atopic dermatitis by Korean medicine. This treatment was enforced from 2019.5.25 to 2019.6.29. And we have confirmed the improvement of itching, rashes and oozing. We recorded photos that includes change of symptoms. Results : After the treatments was done, the grade of VAS and SCORAD was decreased. The VAS grade was decreased from grade 8 to grade 2. The SCORAD score was decreased from 72.1 to 52.1. And itching, rashes, oozing were clearly decreased. Conclusions : Oryeong-san has effect on decreasing itching, rashes and oozing. Also, sleeping time reduced due to itchness was normalized. Thus, It is able that Oryeong-san works on skin desease like atopic dermatitis.
장미색 비강진의 한방 탕약 치료에 대한 연구 : 체계적 문헌 고찰
진한솔,임희영,고우신,윤화정,Jin, Han-Sol,Lim, Hui-Yeong,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2021 한방안이비인후피부과학회지 Vol.34 No.4
Objectives : Pityriasis rosea is an acute and subacute papular scaly disease, and is a disease that mainly resolves spontaneously. However, since the outbreak of COVID-19, the possibility that the disease may occur as a sequelae of the disease and side effects of vaccination has been announced. Methods : We searched articles related to oriental treatment of pityriasis rosea at organized in domestic and foreign DBs. Articles were searched for RCT. The results were summarized in tables and graphs, and meta-analysis was performed. Also, we assessed the risk or bias. Results : As a result of setting the herbal medicine alone treatment as an intervention for pityriasis rosea and Western medicine alone as the control group, total 9 articles were searched. We analyzed them and got the results. The efficient rate of the treatment group was statistically significantly higher than that of the control group. In addition, adverse events were significantly less in the treatment group than in the control group. Conclusions : Herbal medicine treatment can be more effective than Western therapy(mainly anti-histamines and glycyrrhizin injection) for pityriasis rosea. In addition, herbal medicine treatment can be superior to Western treatment for safety. However, the limitations of this study include the small number of articles, no other evaluation indicators other than the efficient rate, and insufficient data such as pathological examination.
梔子乾薑湯 및 한방 치료를 통한 화폐상 습진 치험 1례
진한솔,윤화정 대한한방안이비인후피부과학회 2020 한방안이비인후피부과학회지 Vol.33 No.1
Objective : The purpose of this study is to report the effect of Chijageongang-tang on nummular eczema. Methods : We treated a 21-year-old female patient who have nummular eczema by Korean medicine. This treatment was enforced from 19.8.26 to 19.12.30. And we have confirmed the improvement of itching, rashes and oozing. We recorded photos that includes change of symptoms. Results : After the treatments was done, the grade of VAS was decreased. The VAS grade was decreased from grade 6 to grade 0. And we checked DLQI, all questions of index were improved. Conclusion : After administer Chijageongang-tang, the lesions are clearly improved The itchness was decrease. The scabs disappeared and changed into pigment lesions. Thus, It is able that Chijageongang-tang works on skin desease like nummular eczema.
한방치료를 통해 개선된 화폐상 습진 치험 1례 : 황련아교탕(黃蓮阿膠湯)과 마황부자세신탕(麻黃附子細辛湯)을 중심으로
진한솔,윤화정,고우신,Jin, Han-Sol,Yoon, Hwa-Jung,Ko, Woo-Shin 대한한방안이비인후피부과학회 2021 한방안이비인후피부과학회지 Vol.34 No.1
Objectives : The purpose of this study is to report the effect of Hwangryeonagyo-tang and Mahwangbujasesin-tang(《Shanghanlun》 prescription) on whole-body nummular eczema. Methods : We treated a female patient in her early twenties who has whole-body nummular eczema with Korean medicine. She was treated from 2020.10.8 to 2020.12.11. In this period, she received admission treatments twice because of the recurrence of the symptoms after the first admission. During the treatment, the two herbal medicines were changed depending on the patient's condition. 'Hwangryeonagyo-tang' and 'Mahwangbujasesin-tang' were used as herbal medicine. In addition, herbal external preparations and acupuncture treatment were also performed. The evaluation was conducted by photo comparison, VAS, and DLQI. Blood tests were also conducted for safety assessments. Results : After two months of treatment, the patient's condition improved. The itching and heat sensation decreased, and scabs were placed on the lesion of the eczema, reducing the oozing. VAS of itching decreased from 8 to 0. DLQI was also improved, and the stability of the herbal medicines for liver and kidney was also confirmed through blood tests. Conclusions : Hwangryeonagyo-tang and Mahwangbujasesin-tang helped relieve the itching and heat of eczema in currency. Therefore, it is believed that the proper use of thoes herbal medicine can be expected to have a useful effect on nummular eczema.
Fungal Elicitor와 Exo-phytohormone이 청양고추(Capsicum annuum L.) 종자발아와 2차 대사산물에 미치는 효과
진한솔 ‧ 전우성 ‧ 김성재 ‧ 맹대현 ‧ 박세익 ‧ 이인순 ‧ 박흠대 대구대학교 산업기술연구소 2018 産業技術硏究 Vol.29 No.2
We studied growth rate and synthesis of secondary metabolite as capsaicin and polyphenolic compound during seed germination of Capsicum annuum L. on condition media with fungal elicitor and exo-phytohormone. The condition media was consisted MS (Murashige & Skoog) medium and sucrose for carbon source with different concentration of elicitor and exo-phytohormone. The fungal elicitor was made by Aspergillus niger KCCM 11240 and exo-phytohormone used kinetin, IAA (indole-3-acetic acid). The secondary metabolites were extracted from the seeding tissue by acetone as solvent after 20 days. As a result, the germination of seed was found on the third day and growth of seeding was observed on the seventh day. The capsaicin concentration was had the highest concentration in R0’’ (no exo-phytohormone, 180 mg/ml of fungal elicitor) extract among all extract solutions. The polyphenolic compound was had high concentration in R1’’ (0.1 mg/L of IAA and kinetin, 180 mg/ml of fungal elicitor) extract. The inhibition rate of lipid peroxidation was showed in proportion to the concentration of capsaicin. The effect of NO radical scavenging was measured more activity to natural pepper fruit than seeding cultured in vitro and that activity considered to be phytonutrient included capsaicin and polyphenolic compound. The fungal elicitor inhibited growth and differentiation of seeding, but it induced the synthesis of secondary metabolites. The secondary metabolites were in inverse proportion to total length of seeding. Therefore, capsaicin as phytonutrient can mass-produce by plant tissue culture with biotic stress.
노인성 난청의 한약 치료에 대한 체계적 문헌고찰: 신허(腎虛)을 중점으로
임희영,진한솔,고우신,윤화정,Lim, Hui-yeong,Jin, Han-Sol,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2021 한방안이비인후피부과학회지 Vol.34 No.4
Objectives : This study was conducted to approve the effectiveness and safety of herbal medicine on presbycusis with kidney deficiency. Methods : We searched randomized controlled trials(RCTs) on presbycusis patients diagnosed with kidney deficiency through 10 electronic databases from the start to Sep 7, 2021. Study collection and data extraction, and evaluation of risk of bias were conducted by two independent collaborator. The evaluation of the risk of bias in included RCTs was carried out by using Cochrane risk-of-bias tool. And the data synthesis was conducted by using Review Manager(RevMan, ver.5.4). Results : 1. The treatment group which used herbal medicine(HM) alone was more effective than the control group which used only western medicine(WM) on effective rate of hearing loss. 2. In 3 studies comparing the HM-WM combination treatment group with the control groups using the same WM treatment, the effective rate was statistically significantly higher in the HM-WM combination treatment group. 3. Of the 5 studies that reported adverse reactions, one study reported mild nausea and dizziness, but the difference between the HM treatment group and the WM control group was not statistically significant, and no side effects occurred in other 3 studies. 4. In studies comparing HM and WM, the HM treatment group improved hearing loss, whole blood viscosity, serum TNF-𝛼, IL-1𝛽, IL-6, and oxidative stress indicators better than the WM control group, and there was no significant difference. 5. In studies comparing the HM-WM treatment group with the WM control group, the severity of tinnitus, quality of life, and feelings of anxiety and depression were better in the treatment group than the control group. Conclusions : This study shows that the herbal medicine can improve symptoms of presbycusis with kidney deficiency.