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Naloxone이 실험적 척수손상후 병리학적 변화에 미치는 영향
지문표,김성학,신규만 대한신경외과학회 1985 Journal of Korean neurosurgical society Vol.14 No.1
The pathological lesion in spinal injury is usually more severe in the central gray matter and spreads centrifugally to surrounding white matter. Opiate antagonists, naloxone, by blocking the pathophysiologic effect of endorphins, should increase both mean arterial pressure and spinal cord blood flow and limit neurologic injury. Naloxone produce increase of lateral column blood flow and ameliorate the central grad matter ischemia. We have investigated the effects of naloxone on histopathological change in cats subjected to thoracic cord contusion. The histopathological evaluation of the injured spinal cords in naloxone-treated cats had less tissue damage than would be observed in time-matched standards. The acute histopathology in saline-treated cats had lesions typical of what we would expect in untreated cats, but the chronic histopathology had slightly better than typical that.
지문표,김성학,박동빈,신규만 대한신경외과학회 1984 Journal of Korean neurosurgical society Vol.13 No.3
A case of endodermal sinus tumor in the pineal region of a 12-year-old boy is presented. Preponderance of this tumor occurs in the boys, usually in their second decade. The tumor is characterized by perivascular structure (Schiller-Duval body) which simulate endodermal diverticula of yolk sac origin. His serum alpha-fetoprotein levels was abnormally high. (over 400 ng/㎖)He was treated with operation and irradiation of 4500rad to the whole brain and spinal axis. But he died 6 month later after operation. The authors report a case of endodermal sinus tumor arising from pineal gland and briefly review literature.
지문표,김성학,박동빈 梨花女子大學校 醫科大學 醫科學硏究所 1984 EMJ (Ewha medical journal) Vol.7 No.1
Giant aneurysm occures rarely and it is about 5% of intracranial aneurysm. Giant aneurysm arising from the intradural portion of the internal carotid artery proxi-mal to the origin of the posterior communicating artery present specialsurgical pro-blem. Most of these aneurysms arise in the relation to the origin of the ophthalmic art-ery from the anteromedial aspect of internal carotid artery; however, others arise from the posterolateral portion of the internal carotid artery. In some of the largest ones, the neck is so wide that the site of origin is not clear. As a group, these aneurysms can be called "paraclinoid". In these cases, operative difficulty is presented and complication is well develo-ped, so treatment is marked difficult. We experience a case of giant paraclinoid ane-urysm which was treated by common carotid artery ligation in the neck and rep-ort with brief review of the literature.
요추부 추간공 협착증에서 수술 현미경과 원통형 견인장치를 이용한 추간공 확장술의 효율성: 수술 기법과 임상적 결과
최현민,김태완,지문표,김재오,박관호,김정철 대한척추신경외과학회 2009 Neurospine Vol.6 No.2
Objective: The objective of this study is to evaluate the efficacy of microdecompression (MD) with microscope and tubular retractor in lumbar foraminal stenosis (FS) and to analyze the clinical outcomes. Methods: From January 2006 to December 2007, 22 patients with symptomatic lumbar FS underwent conventional decompressive surgery (CDS) and MD was performed in other 20 patients. Clinical outcome was measured using a Visual Analogue Scale (VAS) and Macnab’s criteria. Spinal instability was determined by radiologic assessment of flexion‐extension radiographs. Results: The CDS group included 14 men and 8 women. The MD group included 14 men and 6 women. The mean age was 66.2 years (range, 46-80 yrs) in the CDS group and 65.4 years (range, 59-74 yrs) in the MD group. Average follow‐up periods were 18.6 months in the CDS group and 16.5 months in the MD group. Mean operating time was 126 minutes in the CDS group and 168 minutes in the MD group. The mean VAS of back pain decreased from 2.68 to 1.36 in the CDS group and from 2.85 to 1.25 in the MD group. The mean VAS score of leg pain decrea- sed from 6.68 to 1.48 in the CDS group and from 6.65 to 1.40 in the MD group. The success rate of CDS group was 86.3 % (19/22), compared with 85.0% (17/20) for MD group. Radiologically, there was no spinal instability. Conclusion: MD could achieve neural decompression and offer an effective treatment of lumbar FS. However it was a technically demanding procedure and effective in limited operative indications. We need to consider long‐term follow‐up. Objective: The objective of this study is to evaluate the efficacy of microdecompression (MD) with microscope and tubular retractor in lumbar foraminal stenosis (FS) and to analyze the clinical outcomes. Methods: From January 2006 to December 2007, 22 patients with symptomatic lumbar FS underwent conventional decompressive surgery (CDS) and MD was performed in other 20 patients. Clinical outcome was measured using a Visual Analogue Scale (VAS) and Macnab’s criteria. Spinal instability was determined by radiologic assessment of flexion‐extension radiographs. Results: The CDS group included 14 men and 8 women. The MD group included 14 men and 6 women. The mean age was 66.2 years (range, 46-80 yrs) in the CDS group and 65.4 years (range, 59-74 yrs) in the MD group. Average follow‐up periods were 18.6 months in the CDS group and 16.5 months in the MD group. Mean operating time was 126 minutes in the CDS group and 168 minutes in the MD group. The mean VAS of back pain decreased from 2.68 to 1.36 in the CDS group and from 2.85 to 1.25 in the MD group. The mean VAS score of leg pain decrea- sed from 6.68 to 1.48 in the CDS group and from 6.65 to 1.40 in the MD group. The success rate of CDS group was 86.3 % (19/22), compared with 85.0% (17/20) for MD group. Radiologically, there was no spinal instability. Conclusion: MD could achieve neural decompression and offer an effective treatment of lumbar FS. However it was a technically demanding procedure and effective in limited operative indications. We need to consider long‐term follow‐up.
김태완,허용석,지문표,김재오,김정철,Kim, Tae Wan,Huh, Yong Suk,Chi, Moon Pyo,Kim, Jae O,Kim, Jung Chul 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.11
Althogh spinal epidural lipomatosis is relatively rare, it is a widely recognized complication of excess exogenous glucocorticoids. We report 4 cases of epidural lipomatosis. None of the patients had definitive history of steroid treatment, obesity, or diabetes mellitus, but all had sciatica and radiating pain. In all cases, the authors removed excess amount of epidural fat with surgery after which significant improvement of symptoms was noted.
결핵성 뇌막염에 속발된 척수공동증의 수술적 치료법 : 증례보고 Report of 4 cases
장범주,하은신,지문표,김재오,김정철 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.9
The authors report our recent experience with 4 cases of syringomyelia that had developed secondary to tuberculous meningitis. Three cases of syringomyelia were treated by syringoperitoneal shunt and 1 case, by syringosubarachnoid shunt. Postoperatively upper and lower extremity pain that had persisted in all the patients was relieved in all the patients, but improvement in limb sensation was noted in only 1 case lmprovement in limb motor power was noted in 3 cases. The clinical presentation surgical consideration, and pathogenesis of syringomyelia is discussed together with a review of the literature.
다발성 척추골절을 동반한 비분비형 다발성 골수종 1례 - 증례보고 -
허용석,박관호,지문표,김재오,김정철,Huh, Yong-Seok,Park, Kwan-Ho,Chi, Moon-Pyo,Kim, Jae-O,Kim, Jung-Chul 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.12
A case of nonsecretory multiple myeloma in a 66 year-old-woman is reported. At first, she complained severe neck pain and radiologic finding showed C2 pathologic fracture. She complained severe low back pain 4 month later and L1 compression fracture was found. The lumbar MRI showed a 1.4cm-sized round enhancing lesion in the body of T12. Bone marrow aspiration biopsy at L1 spine showed a few polymorphous and small nests of mononuclear cell. L1 lamina bone biopsy showed many abnormal plasma cells. Pathologic diagnosis was multiple myeloma. However, plasma electrophoresis and protein immunoelectrophoresis of serum and urine of patient were normal. So, it is a nonecretory multiple myeloma case and the incidence of nonsecretory multiple myeloma is known to about 1% of all multiple myeloma.