요추 추간판 탈출증 환자의 음낭부 통증에 대한 장요근 MET를 병행한 한의학적 치료 증례보고

주환수(Hwan Soo Joo),한창(Chang Han),김태윤(Tae Yoon Kim),서창용(Chang Yong Suh),이성엽(Sung Yub Lee),신재권(Jae Kwon Shin),도호정(Ho Jeong Do) 대한스포츠한의학회 2016 대한스포츠한의학회지 Vol.16 No.1

Objectives To evaluate the effect of iliopsoas muscles energy techniques(MET) combined with Korean medicine treatment in genital pain and other symptoms caused by lumbar disc herniation. Methods To evaluate the pain and function, visual analog scale(VAS), oswestry disability index(ODI), manual muscle test(MMT), straight leg raising test(SLRT) was measured. Results After treatment of 6 weeks, lower back pain declined from VAS 9 to 4, leg pain from VAS 6 to 3, genital pain from VAS 6 to 1. ODI score reduced from 84 to 37.78. MMT improved from Ⅲ/Ⅴ to Ⅴ/Ⅴ, and SLRT recovered from 30/50 to 70/70. Conclusions Treatment of iliopsoas MET and Korean medicine treatment is effective for genital pain and other symptoms caused by lumbar disc herniation. But further studies are required.

파킨슨병에 대한 국내 한의학 관련 실험 연구 동향

주환수 ( Hwan Soo Joo ),유옥철 ( Ok Cheol Yu ),한창 ( Chang Han ),양규진 ( Kyu Jin Yang ),이성엽 ( Sung Yub Lee ),문혜연 ( Hye Yeon Moon ) 대한한방신경정신과학회 2017 동의신경정신과학회지 Vol.28 No.3

Objectives: The purpose of this study is to review experimental studies of Parkinson`s Disease in Korean medical journals, which have been published since 1990. Methods: Experimental studies related to Parkinson`s disease published in Korean medical journals, registered with Korea research foundation, were searched. Articles were grouped into journal of publication, subject, and publication year. Experimental study subjects and models were analysed. Results and Conclusions: Twenty-two articles about experimental studies of Parkinson`s Disease in Korean medical journals were included in our review. There were 13 articles in which herbs were used for treatment, 4 articles in which bee venom was used for treatment, 4 articles in which acupuncture was used for treatment, and 1 article in which pharmacopuncture was used for treatment. Most of the studies used experimental models of MPTP-induced Parkinson`s disease and MTT assay was used to analyse cell toxicity and cell viability. Pole test, rotarod test, Morris water maze test, and forced swimming test were commonly used to analyse MPTP-induced behavioral deficits in animals. Analysis on experimental studies of Parkinson`s disease was categorized into the subjects of dopaminergic cell protective effect, cell-apoptosis protectiveness, anti-inflammatory effect, and anti-oxidative effect.

건강보험심사평가원 데이터의 분석을 통한 체성기능부전 환자의 특성 및 M99 진단명의 사용현황 분석

신재권,주환수,이성엽,신예슬,고원일,박기병,김민규,하인혁,Shin, Jae-Kwon,Joo, Han-Soo,Lee, Seong-Yup,Shin, Ye-Sle,Ko, Won-Il,Park, Ki-Byung,Kim, Min-Kyu,Ha, In-Hyuk 척추신경추나의학회 2016 척추신경추나의학회지 Vol.11 No.1

Objectives : The aim of this study is to assess the usage of diagnosis codes for somatic dysfunctions and the general characteristics of patients diagnosed with the code, by analyzing health insurance data provided by the Health Insurance Review & Assessment Service(HIRA) of Korea. This investigation is intended to outline future and willing to contribute to further use of diagnosis code and the approach of Oriental Medicine to somatic dysfunction. Materials and Methods : By analyzing HIRA data, those diagnosed with M99 codes, a code attributed to somatic dysfunction, were selected for analysis. Patients included were assessed for the relevant general characteristics, and the specific diagnostic criteria. The current usage rates and noteworthy characteristics of diagnostic codes of somatic dysfunctions were assessed. A comparative analysis between clinical departments and subcategories, and a comparative analysis to data of 2014 was conducted. Results : Patients given M99 codes constituted a small minority of all patients diagnosed in 2011 as shown by HIRA data. The codes were more frequently to older patients, females, outpatients, and those who filed for Health Insurance compensation. Medical institutions participating in the diagnosis were mostly primary care facilities, usually specializing in orthopedic(Western medicine sector) and internal medicine (Oriental Medicine sector). The most registered code in 2011 and 2014 was M995. The same trend can be observed in Oriental/Western medicine institutions and Public health center, on the other hand, between them, have some different patterns both 2nd and 3rd. Conclusions : This investigation is that of current usage of diagnostic codes of somatic dysfunction. HIRA insurance claim data was analyzed. Based on the current results, more precise diagnostic standards of somatic dysfunction are warranted. This study will provide a foundation for future Oriental Medicine approach to somatic dysfunctions.

Establishment and Selection of Indicator Materials for Cervi Parvum Cornu Pharmacopuncture

양규진,이기범,김노현,김태규,기유미,주환수,서창용,이인희,정화진,하인혁,이재웅 대한침구의학회 2017 대한침구의학회지 Vol.34 No.4

Background: Recently, Cervi Parvum Cornu pharmacopuncture has been widely used. But no studies on the indicator materials for Cervi Parvum Cornu pharmacopuncture have been conducted. The aim of this study was to select indicator materials that would aid in the uniform preparation of standardized Cervi Parvum Cornu pharmacopuncture. Methods: Three lots of Cervi Parvum Cornu pharmacopuncture were analysed. Each lot was prepared using the same methods and materials. Chondroitin sulfate, alanine, and leucine were selected as the indicator materials for Cervi Parvum Cornu. For standardization, chondroitin sulfate analysis was performed using the colorimetric method, while alanine and leucine were analyzed using liquid chromatography–mass spectrometry (LC–MS). Results: Analysis of the three lots of Cervi Parvum Cornu pharmacopuncture found chondroitin sulfate levels of 108.9 ± 17.3 ug/ml, 118.8 ± 5.0 ug/ml and 112.3 ± 11.9 ug/ml. Alanine levels were 44.9 ± 2.8 ug/ml, 44.6 ± 0.3 ug/ml, and 43.9 ± 0.2 ug/ml. Leucine levels were 29.6 ± 0.7 ug/ml, 29.0 ± 0.1 ug/ml, and 29.4 ± 0.1 ug/ml. Conclusion: These results suggest that chondroitin sulfate, alanine, and leucine may be useful for the standardization of Cervi Parvum Cornu pharmacopuncture.

샤르코 마리투스 병 환자의 족관절 통증에 대한 족관절 추나를 병행한 한의학적 치료 증례보고

김태윤,한창,이제균,박종훈,금창준,오재우,주환수,Kim, Tae-Yoon,Han, Chang,Lee, Je-Kyun,Park, Jong-Hoon,Kum, Chang-Jun,Oh, Jae-Woo,Joo, Hwan-soo 척추신경추나의학회 2015 척추신경추나의학회지 Vol.10 No.1

Background : Charcot Marie Tooth disease can cause muscle weakness and foot deformity. Ankle pain induced by foot deformity affect patients' gait pattern and quality of life. Objectives : The purpose of this study is to evaluate the traditional Korean medicine treatment for ankle pain induced with Charcot-Marie Tooth Disease, especially Chuna manual therapy on ankle joints. Methods : One patient was treated with acupuncture, phamacopuncture, herbal medication and chuna manual therapy on ankle joints. To evaluate the pain of ankle, lower back and lower extremity, visual analog scale(VAS) was measured. Results : After treatment for 5 week, the pain of ankle joint was declined from VAS 6 to VAS 2. Conclusions : Traditional Korean medicine treatment including acupuncture, pharmacopuncture, herbal medication and Chuna manual therapy is effective for ankle pain with foot deformity. But further studies are required to prove the effectiveness of Chuna manual therapy on ankle joints.

지역별 두중(杜仲)의 지표성분 및 항산화 활성 비교

유옥철 ( Ok Cheol Yu ),최성률 ( Sung Ryul Choi ),주환수 ( Hwan Soo Joo ),한창 ( Chang Han ),문혜연 ( Hye Yeon Moon ),정화진 ( Hwa Jin Jung ),정찬헌 ( Chan Hun Jung ) 대한본초학회 2018 大韓本草學會誌 Vol.33 No.6

Objectives : It is necessary to manage herbal medicines based on effectiveness by comparing the efficacy of herbal medicines by region. In this study, we compared anti-oxidative activity and marker compounds of Eucommiae Cortex by regional groups. Methods : Eucommiae Cortex grown and harvested in Gangjin, Sancheong, Yeongwol, Jangsu, and Jecheon were used. Eucommiae Cortex was extracted in distilled water at 100℃ for 3 hours, and filtered. filtered. Extract samples were freeze-dried at -80℃. Comparison of anti-oxidant activity in Eucommiae Cortex samples from regional groups was measured in 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, 2,2'-azino-bis(3-ethylbenzothiazoline- 6-sulphonic acid) (ABTS) free radical scavenging, and ferric reducing antioxidant power (FRAP) between regional groups of Eucommiae Cortex. In addition, high-performance liquid chromatography (HPLC) analysis was conducted to compare pinoresinol diglucoside concentration by regional groups. Results : HPLC analysis found that pinoresinol diglucoside concentration, widely known as the marker compound of Eucommiae Cortex, was the highest in Gangwon Yeongwol. There was a significant difference in anti-oxidative activity of Eucommiae Cortex between regional groups as discovered in DPPH, ABTS and FRAP assays. DPPH free radical scavenging was the highest in Jeonbuk Jangsu. ABTS free radical scavenging was the highest in Jeonbuk Jangsu and Chungbuck Jecheon. FRAP was the highest in Jeonbuk Jangsu. Conclusions : Although pinoresinol diglucoside concentration was high, anti-oxidative activity was not proportionately high. Pinoresinol diglucoside concentration was the highest in Gangwon Yeongwol. Anti-oxidative activity was the highest in Jeonbuk Jangsu.

외상성 말초신경손상의 한의학적 치료에 대한 국내 연구 동향 고찰

이성엽(Sung-Yup Lee),이윤재(Yoon-Jae Lee),소민지(Min-Ji So),정유화(You-Hwa Jung),서창용(Chang-Yong Suh),주환수(Hwan-Soo Joo),신재권(Jae-Kwon Shin) 대한스포츠한의학회 2016 대한스포츠한의학회지 Vol.16 No.1

Objectives The purpose of this study is to examines the domestic study trends on traumatic peripheral nerve injury treated with Korean medicine. Methods We investigated the studies on Korean medicine treatment for Traumatic Peripheral Nerve Injury via searching 6 online databases. Results As a result, 14 records were found to be analyzed according to their published year, the types of study, intervention, injured nerve, trauma and relevant outcome. Researchs have been continuously published in a form of clinical case report since 2012. The most treated interventions were acupuncture and herbal medication. Brachial plexus damage was the most common peripherial injury. Traffic accident was the first cause, and the mostly used tools for reports were visual analogue scale and range of motion. Conclusions Reviewing the domestic trends of studies on Korean medicine treatment for traumatic peripheral nerve injury would be conjugated to establish a basic knowledge of the future study. It is anticipated that this review benefits the future in-depth study on the treatments for traumatic peripheral nerve injury in terms of Korean medicine.