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주호연,채명훈,임주한,이현규,이문희,김철수,박영훈 전남대학교 의과학연구소 2013 전남의대학술지 Vol.49 No.3
At the time of diagnosis, about 20% of patients with gastric cancer have stage IV disease involving the liver, lung, and bone. Brain metastasis from gastric cancer is exceedingly rare, with an incidence of <1% of clinical cases. A 59-year-old man was admitted with hearing loss in the left ear and left facial palsy for 1 month. A magnetic resonance imaging scan revealed a tumor in the cerebellopontine angle that extended to the inner auditory canal and that was clinically diagnosed as acoustic neuroma. After complete resection,histological examination showed metastatic poorly differentiated carcinoma. Further investigation revealed advanced gastric cancer involving the antrum with no evidence of the involvement of other sites except the brain parenchyma. Palliative total gastrectomy was performed and the surgical specimen revealed a poorly cohesive carcinoma that was histopathologically identical to that of the resected brain tumor. Here we report this rare case of gastric cancer that initially presented as a solitary brain metastasis mimicking acoustic neuroma.
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COVID-19 발생 전후 작업치료사의 감염관리 인식 및 수행도 비교 조사
주호연,차태현 한국융합학회 2022 한국융합학회논문지 Vol.13 No.3
This study surveyed 101 occupational therapists who were performing occupational therapy before and after the COVID-19 outbreak to compare their perceptions and performance of hand washing, use of personal protective equipment, and infection control of surrounding environment. Mann-Whitney U test, Kruskal wallis H test, Wilcoxon signed-rank test, Pearson's correlation coefficient were used analyzed. As a result, it was confirmed that they received better infection control education after the outbreak compared to before the outbreak of COVID-19, and their experience with infectious diseases was lower. In addition, it was found that the perception and performance of infection control in hand washing, personal protective equipment, and surrounding environment cleaning were improved after the outbreak compared to before the outbreak of COVID-19. However, to this day, hand washing for more than 40 seconds in running water recommended by the Korea Centers for Disease Control and Prevention, cleaning the treatment room, and disinfection of treatment tools are still in need of improvement. Through this study, infection control education should be repeated regularly to minimize the occurrence of infectious diseases, and It will be a basic data that can be used in infection control education and follow-up studies for occupational therapists in the future. 본 연구는 COVID-19 발생 전후에 작업치료를 수행하고 있는 작업치료사 101명을 대상으로 손 씻기, 개인 보호 장비 사용, 주변 환경 정리의 감염관리에 대한 인식과 수행을 비교하고자 설문조사를 실시했으며, 맨-휘트니 U 검정(Mann-Whitney U test), 크루스칼-왈리스 H 검정(Kruskal-wallis H test), 윌콕슨 부호 순위 검정(Wilcoxon signed-rank test), 피어슨 상관분석(Pearson's correlation coefficient)을 사용해 분석하였다. 그 결과, COVID-19 발생 이전보다 발생 이후에 감염관리 교육을 더 잘 받았고 감염성 질환의 경험이 낮은 것으로 확인되었다. 또한, COVID-19 발생 이전보다 발생 이후에 손 씻기, 개인 보호장비 사용, 주변 환경정리에서의 감염관리에 대한 인식 및 수행이 향상된 것으로 나타났다. 하지만 현재까지도 질병관리청에서 권고하는 흐르는 물에서 40초 이상의 손 씻기와 치료실 청소 및 치료 도구의 소독은 개선이 필요한 실정이다. 본 연구를 통하여 감염성 질환의 발생을 최소화하기 위해 감염관리 교육을 정기적으로 반복해야 하며, 향후 작업치료사를 대상으로 하는 감염관리 교육 및 후속 연구에서 활용할 수 있는 기초자료가 될 수 있을 것이다.
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증례 : 감염; Staphylococcus lugdenensis에 의한 요근 농양 1예
채명훈 ( Myoung Hun Chae ),주호연 ( Ho Yeon Joo ),이현정 ( Hyun Jung Lee ),김진철 ( Jin Chul Kim ),백지현 ( Ji Hyeon Baek ),임재형 ( Jae Hyoung Im ),이진수 ( Jin Soo Lee ) 대한내과학회 2014 대한내과학회지 Vol.86 No.3
Staphylococcus lugdunensis is a member of coagulase-negative staphylococci (CoNS), an uncommon microbial culture isolate with virulent potency. Although CoNS are common skin commensals, and often regarded as contaminants or colonizers when isolated from clinical specimen cultures, the clinical course and microbiological characteristics of Staphylococcus lugdunensis may resemble those of Staphylococcus aureus rather than other CoNS. Invasive infectious diseases such as infective endocarditis, peritonitis, skin and soft tissue infection, vascular prosthetic infection, septicemia, and osteomyelitis have been found to be associated with Staphylococcus lugdunensis. Here we report the first case of psoas abscess caused by methicillin-sensitive Staphylococcus lugdunensis in Korea.
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Prevention of Comorbidity and Acute Attack of Gout by Uric Acid Lowering Therapy
주고운,권성렬,임미진,정경희,주호연,박원 대한의학회 2014 Journal of Korean medical science Vol.29 No.5
The object of this study was to evaluate the effect of uric acid lowering therapy in reducingthe new development of comorbidities and the frequency of acute attacks in goutpatients. We retrospectively reviewed patients who were diagnosed to have gout with atleast 3 yr of follow up. They were divided into 2 groups; 53 patients with mean serum uricacid level (sUA) < 6 mg/dL and 147 patients with mean sUA ≥ 6 mg/dL. Comorbidities ofgout such as hypertension (HTN), type II diabetes mellitus (DM), chronic kidney disease,cardiovascular disease (CVD) and urolithiasis were compared in each group at baseline andat last follow-up visit. Frequency of acute gout attacks were also compared between thegroups. During the mean follow up period of 7.6 yr, the yearly rate of acute attack andthe new development of HTN, DM, CVD and urolithiasis was lower in the adequatelytreated group compared to the inadequately treated group. Tight control of uric aciddecreases the incidence of acute gout attacks and comorbidities of gout such as HTN, DM,CVD and urolithiasis.
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Seasonality of Gout in Korea: A Multicenter Study
최효진,이지수,이주현,윤보영,김현아,서창희,최상태,송정수,주호연,최성재,이찬희,신기철,전재범,백한주 대한의학회 2015 Journal of Korean medical science Vol.30 No.3
The object of this study was to evaluate the seasonality of gout in Korea. We retrospectivelyexamined data from 330 patients seen at nine rheumatology clinics, treated with uratelowering therapy (ULT) more than one year after stopping prophylactic medication. Demographic data, clinical and laboratory features, and seasonality of gout onset andflares were collected. Season was classified in three-month intervals. The mean age was52.2 yr and mean disease duration was 26.8 months. The male to female count was318:12. The onset of acute gouty attacks was obtained in 256 patients. Gout developedmost commonly in summer season (36.7%) (P < 0.001) and in June (15.6%, P = 0.002). During ULT, there were 147 (male 97.3%) gout flares. Although there was no statisticallysignificant difference, gout flares were more common in summer (30.6%). Aggravatingfactors were identified in 57 flares: alcohol (72.0%) was most common. In the patientswho attained target serum uric acid (< 6 mg/dL) at the end of prophylaxis, gout flares werehigh in fall (35.8%) and September (17.0%). In Korea, the summer is most commonseason of gout onset and there is a tendency for gout flares to increase during ULT insummer/fall season.
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