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3차원 볼륨 렌더링을 이용한 가상 돌출형 전립선 부피 평가
성열훈,주용현,임재동,최보영,Seoung, Youl-Hun,Joo, Yong-Hyun,Rhim, Jae-Dong,Choe, Bo-Young 한국의학물리학회 2009 의학물리 Vol.20 No.4
2차원의 영상을 이용한 돌출형 전립선 비대증의 부피 평가방법에서 돌출부위를 포함시킬 경우와 포함시키지 않을 경우의 부피변화를 3차원 볼륨 렌더링(volume rendering, VR)을 이용하여 비교 평가하고자 한다. 돌출형 전립선 부피측정을 위한 가상 전립선 모델은 곤약을 이용해 임의로 평균 1 cm 정도로 돌출되도록 하여 10 ml에서 각각 10 ml씩 부피를 변화시켜 100 ml까지 총 10 개의 모델을 제작하였다. 이 때 제작된 모델의 부피측정은 64 channel 전산화단층촬영(computed tomography, CT)과 3.0 Tesla 자기공명영상(magnetic resonance image, MRI)을 이용하여 획득된 3차원 볼륨 영상자료로 계측하였다. 산출한 CT와 MRI영상들의 3차원 볼륨데이터 근접성 평가를 위해 wilcoxon 부호순위(signed rank) 검정을 하였다. 또한 획득한 영상자료는 3차원 영상처리를 통하여 볼륨 렌더링으로 재구성한 후 타원체부피공식법을 이용하여 돌출부위를 포함시킬 때와 포함하지 않을 때의 부피를 구하였다. 이 때 돌출 유무에 따라 각각 측정된 부피와 3차원 볼륨 렌더링의 부피를 wilcoxon 부호순위(signed rank) 검정을 사용하여 유의성을 평가했으며 상관계수(pearson's correlation coefficient, r)를 사용하여 상관관계를 분석하였다. 계측된 가상 전립선 모델의 돌출부위길이는 CT에서 $0.90{\pm}0.18\;mm$, MRI에서 $0.75{\pm}0.11\;mm$이었으며, CT와 MRI에서 계측된 3차원 영상 부피의 p-value는 0.414로 유의한 차이는 없었다. 그러나 MRI에서 측정된 3차원 영상 부피와 2차원 영상에서 돌출부위를 포함시킬 때의 p-value는 0.005인 반면 포함하지 않을 때의 p-value는 0.139로 나타났으며, CT에서도 측정된 3차원 영상 부피와 2차원 영상에서 돌출부위를 포함시킬 때의 p-value는 0.005인 반면 포함하지 않을 때의 p-value는 0.057로 나타났다. 돌출형 전립선의 부피측정은 돌출부위를 제외하고 상하길이를 측정하는 것이 3차원 볼륨 렌더링에 의한 부피 값과 더 가까운 부피 값을 얻을 수 있었다. This study is to compare the accuracy of evaluation regarding the volume of the prostate, which three-dimensional volume rendering was produced the shape of protrusion, by measuring two kinds of craniocaudal length from the top of the protrusion and from the exclusion of the protrusion as the starting points. For the imaginary protrusion prostate models, total of 10 models were roughly made by using devils-tongue jelly and changing each of the 10 ml of capacity from 10 ml to 100 ml. For the protrusion prostate models aimed at estimating the real volume, through 64 cannel computed tomography (CT) and 3.0 tesla magnetic resonance image (MRI) were conducted by planimetry technique from three-dimensional volume rendering. And then we performed to evaluate on significance of these volumes by wilcoxon signed rank test. Also the obtained volumes data by ellipsoid volume formula were measured the volume of protrusion prostate models two times with each method using the two kinds of craniocaudal length from top of the protrusion and from exclusion of the protrusion as the starting points. Finally, the significance of differences using wilcoxon signed rank test was evaluated between the real volume by planimetry technique and the measured volume by ellipsoid volume formula from three-dimensional volume rendering. The average of the protrusion length on the models was $0.90{\pm}0.18\;mm$ in CT and was $0.75{\pm}0.11\;mm$ in MRI. There were not statistically significant difference between MRI and CT from the volume of protrusion prostate models (p=0.414). In MRI (p=0.139) and CT (p=0.057), there were not statistically significant difference between the real volume by planimetry technique and the measured volume by ellipsoid volume from exclusion of the protrusion as the starting points. While, there were statistically significant difference between the real volume by planimetry technique and the measured volume by ellipsoid volume from top of the protrusion as the starting points in MRI (p=0.005) and CT (p=0.005). For the accurate measurement of the protrusion prostate models, the craniocaudal length of the prostate should be measured from the exclusion of the protrusion as the starting points.
3차원 의료영상진단기기를 이용한 가상 전립선 용적 측정
성열훈,주용현,최보영,Seoung, Youl-Hun,Joo, Yong-Hyun,Choe, Bo-Young 대한의용생체공학회 2010 의공학회지 Vol.31 No.4
Recently, advance on various modalities of diagnosing, prostate volume estimation became possible not only by the existing two-dimension medical images data but also by the three-dimensional medical images data. In this study, magnetic resonance image (MRI), computer tomography (CT) and ultrasound (US) were employed to evaluate prostate phantom volume measurements for estimation, comparison and analysis. For the prostate phantoms aimed at estimating the volume, total of 17 models were developed by using devils-tongue jelly and changing each of the 5ml of capacity from 20ml to 100ml. For the volume estimation through 2D US, the calculation of the diameter with C9-5Mhz transducer was conducted by ellipsoid formula. For the volume estimation through 3D US, the Qlab software (Philips Medical) was used to calculate the volume data estimated by 3D9-3Mhz transducer. Moreover, the images by 16 channels CT and 1.5 Tesla MRI were added by the method of continuous cross-section addition and each of imaginary prostate model's volume was yielded. In the statistical analysis for comparing the availability of volume estimation, the correlation coefficient (r) was more than 0.9 for all indicating that there were highly correlated, and there were not statistically significant difference between each of the correlation coefficient (p=0.001). Therefore, the estimation of prostate phantom volume using three-dimensional modalities of diagnosing was quite closed to the actual estimation.
일회용 Contrast media injector connecting tube 성능에 대한 연구
박신영(Sin Young Park),안승원(Sung Won Ahn),차현석(Hyun Suk Cha),주용현(Yong Hyun Joo),민부기(Boo Gi MIN),고중석,민관홍 대한인터벤션영상기술학회 2017 대한인터벤션영상기술학회지 Vol.20 No.1
목적 : 국민권익위원회는일회용의료기기의기준확립및재사용을금지할것을권고하였다. 이에 Intervention 시술시 사용되는 의료기기 중, 일회용 품목인 조영제자동 주입기연결선(Contrast media injector connecting tube)의 성능및 비용적인 면을 고려하여 Intervention시술 에 적합한 Connecting tube type을 알아보고자 한다. 대상 및 방법 : 현재 국내 출시된 Connecting tube중 연결부의 재질이 금속인 것과,보다 저렴한 플라스틱으로 제작된 제품을 Microangiography와 비슷한 환경을 제작하여 비교하였다. Connecting tube의 성능 평가 항목은 연결능력(Connection ability), 압력능력(Pressure ability),고정능력 (Non-moving ability), 고정 시 psi변화(psi change during fixation)로 나누었다. 측정 편차에 따른 오차를 최소화하기 위하여 10회 측정하여 평균 값으로 계산하였으며, 방사선사 3명이 각각 동일한 방법으로 평가 및 분석 하였다. 결과 : 연결능력은 플라스틱Connecting tube가 우수한 성능을 보였다. 압력 능력은 유의하지 않은 것으로 나타나 제품 간성능의 차이는 없었다(p=0.727). 고정 능력은 금속 Connecting tube가 더 우수한 성능을 보였다(p=0.01). 그러나 고정능력 보완방법인 연결부 고정 시 psi의 변화 실험에서 세 가지 제품 모두 10~50psi 만이 증가하는 것을 확인하였다(p=0.028). 결론 : Connecting tube type별 비교 실험 결과 고정능력만 보완 된다면 플라스틱Connecting tube의 성능이 금속 Connecting tube 보다 동등하거나 우수하였다. 이에 비용적인 측면을 함께 고려한다면 플라스틱 Connecting tube의 연결부를 고정 후 사용이 임상에 가장 적합하다고 사료된다. Purpose : Reuse of medical devices is decreasing as the medical environment changes. so compare the contrast media injector connecting tubes of medical devices used in the procedure and to find out the appropriate connecting tube type. Materials and methods : Metal, plastic luer connector in the domestic market were compared with the microangiography similar environment. The performance criteria of the connecting tube were divided into connection ability, pressure ability, non-moving ability and psi change during fixation. In order to minimize the error according to the measurement error, the mean value was measured five times, and the three radiologists were evaluated and analyzed in the same manner. Results : The connecting ability of plastic connecting tube was excellent, pressure ability was no difference in between products, non-moving ability showed good performance of metal connecting tube. however, it was confirmed that psi (pounds-per-square-inch) increased by 10 ~ 50 psi change during fixation when microcatheter luer connector was fixed. Conclusions : Results of comparison test of connecting tube type, excluding the fixing ability the plastic connecting tube was better than or equal to that of the metal connecting tube in the evaluation area. Considering the cost side, it is most suitable to use plastic connecting tube after fixing the connector luer.