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기귀보신탕 투여가 야뇨증 환아에 미치는 영향에 관한 임상적 연구
주봉현,장지혜,정민정,이승연,Ju, Bong-Hyun,Jang, Ji-Hye,Jeong, Min-Jeong,Lee, Seung-Yeon 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.2
Objective : The objective of this study is to assess the clinical effect of Gikwuibosin_tang on nocturnal enuretic children. Methods : This clinical study was carried out with 15 cases of children aged 5 to 10 years old who visited the 00 Oriental Clinic between February 2005 and August 2005 and who were diagnosed as the nocturnal enuresis. The data of present symptom and improvement progress was collected a telephone interviews with their mother. Results : The total number of children was 15, 10 of them were male and 5 were female. Sex ratio was 2:1. Patients under 6 years old were 9(60%). After the treatment of oriental medicine der $2{\sim}3$ months, 6 of the children were improved completely and 7 of them were cured quite well, 2 of them were recovered in a half way. the treatment performed very well so there's no case which were not improved at all. And a ratio of the perfect cure was 40%. Following-up survey by telephone, the treatment were performed completely for 8 of them and 4 of them were almost improved but 3 of them were not improved. And a ratio of the perfect cure was 53.3%. Conclusion : Gikwuibasin-tang is effective in the treatment of nocturnal enuretic children. Further study is needed with more cases.
주봉현,김두환,곽동주,성열문 한국조명·전기설비학회 2012 한국조명·전기설비학회 학술대회논문집 Vol.2012 No.10
각종 유해물질의 살균이나 탈취를 위한오존의 효율적 생성법에는 연면방전을 비롯하여 코로나방전 그리고 무성방전이 이용 되고 있다. 본 연구에서는 보다 낮은 전압조건하에서 방전의 발생 및 유지가 가능한 무성방전을 이용한 오존발생기를 설계 제작하였다 즉 원통형의 방전관 내에 유전체로써 유리 글라스를 삽입하고 코일형의 고전압측전극을 이용하여 오존발생 및 생성효율에 미치는 전극피치의 영향을 검토하였다 전극피치간격의 변화는 전극의 면적 및 전자 활동공간의 변화를 의미하는 것으로 방전의 효율에 영향을 미칠 것으로 생각 된다 실험결과 전극피치의 간격이 좁을수록 발생되는 오존농도가 증가하였으며 나선형 전극의 피치간격이 1[mm] 일 때 가장 우수한 오존발생특성을 나타내었다.
C57BL/6N 마우스 탈모모델에서 미세다륜침과 영지추출물이 모발성장에 미치는 영향
주봉현,유선애,강경화,이승연,Ju, Bong Hyun,Yu, Sun Ae,Kang, Kyung Hwa,Lee, Seung Yoen 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.2
Objectives This study was carried out to investigate the effect of Ganoderma lucidum extract (GLE) and microneedle therapy system (MTS) on hair growth in an alopecia model of C57BL/6N mice. Methods Five-week old mice were depilated and separated in 4 groups ; CON (50% EtOH), MXD (5% Minoxidil), MTS and GLE + MTS. The treatments were applied twice a week for 3 weeks. The hair growth was determined photographically, the hair density, thickness and length were identified by Folliscope and the weights of body and organs were measured. In dorsal skin tissue, the expression of hair growth-related gene and protein was analyzed by RT - PCR or Western blot. In addition, the hair follicles in the dermis were observed by H&E staining. Results The promotion of hair growth was observed in GLE + MTS and MTS compared to CON. The hair density, thickness and length were also improved in GLE + MTS and MTS compared to CON. The mRNA expression of TGF-${\alpha}$, TGF-${\beta}1$, IGF-1, PRL and PL and the protein expression of VEGF and IGF-1 were increased in GLE + MTS and MTS compared to CON. The hair follicles and hair root growth were improved in GLE + MTS and MTS compared to CON. In the above results, GLE + MTS were more effective than MTS. Conclusions These results suggest that GLE and MTS has a hair growth activity and can be useful for the treatment of alopecia.
주봉현,최윤경,유선애,이승연,Ju, Bong Hyun,Choi, Yun Kyung,Yu, Sun Ae,Lee, Seung Yeon 대한한방소아과학회 2013 대한한방소아과학회지 Vol.27 No.3
Objectives This clinical study is aimed to examine the effects of herbal medication and pharmacopunture on child with different types of alopecia. Methods 13 year old girl was treated with Hominis placenta pharmacopuncture microneedle therapy system and Ganoderma lucidum pharmacopuncture mesotherapy on the alopecia lesion for 20 months. Herbal medication, meridian pharmacopuncture therapy and physiotherapy were also used to reduce physical symptoms. Results The patient had a relapse of hair loss with changing alopecia types, but eventually alopecia has been resolved and maintained throughout the Korean medicine treatment. Conclusions This study shows the effect of the Korean medical treatments for a pediatric patient with alopecia. And more research is needed to study about patients with different types of alopecia.