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      • 총수담관의 막양구조(Web) 1예

        주남영,도복태,임원준,석욱,오용창,김명준,우종길,정정명 인제대학교 1998 仁濟醫學 Vol.19 No.1

        총수담관 막양구조는 1939년 Carter 등에 의해 처음 보고된 이래 세계적으로는 약40예, 국내는 아직 많이 보고되지 않은 드문 질환이다. 저자들은 열을 동반하지 않고 황달 및 심와부 동통을 주소로 내원한 56세 남자 환자에서 내시경적 역행술로 진단하고 수술로 치료한 총수담관 막양구조 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Common bile duct(CBD) web is a very rare disease. Since its first description in 1939 by Carter, about 40 cases have been reported in the world. This was found in a 56-year-old man who had the epigastralgia and jaundice without fever. He was diagnosed as CBD web by endoscopic retrograde cholangio-pancreatography (ER-CP) and treated with operation. We report this rare case with the review of literature.

      • 급성 복통 및 호흡기 증상이 현저한 알레르기성 육아종증 1례

        김명준,윤선희,김국규,오용창,주남영,임외자,우종길 대한알레르기학회 1995 천식 및 알레르기 Vol.15 No.4

        Churg-Strauss syndrome is a disorder of hypereosinophilia and systemic vasculitis in subjects with asthma and allergic rhinitis. Clinically multiple organ systems can be involved with various manifestations of disease of lung, heart, skin, musculoskeletal system, and gastrointestinal, hepartobiliary tt act. Ive experienced a case of Churg-Strauss syndrome presenting as acute abdol men in a 54-year-old male. During the period of treatment, we observed migrating pneumonic infiltration and mechanical obstruction of small intestine. We performed exploratory laparotomy and small bowel resection. We observed granulomatous vasculitis of small and medium sized mesenteric vessel and marked eosinophilic infiltration in the small intestinal biopsy. We prescribed dexamethasone 10mg/day for patient. Patients symptom is resolved and then discharged.

      • 상부위장관 용종성 병변 265예의 내시경 및 병리조직 소견에 대한 연구

        설상영,장윤식,윤상조,주남영,김민기,이상욱 인제대학교 1998 仁濟醫學 Vol.19 No.2

        저자는 1988년 7월부터 1997년 12월까지 부산백병원에서 내시경 검사를 통해 상부 위장관의 용종성 병변이 확인된 265명 환자의 274 용종성 병변에서 용종을 올가미법, 박리 생검술, "O" ring 결찰술을 이용하여 절제술을 시행하였으며, 이들을 대상으로 임상적 및 조직학적 소견을 분석하였다. The gastrointestinal polyp is a premalignant lesion in varying degree. Polyps in the gastrointestinal tract can be removed by surgical excision, electrosurgical method, cryotherapy, regional radiotherapy and laser therapy with some limitations. Advance in fibroptic endoscopy have improved diagnostic capabilities and management in patients with gastrointestinal polyps and endoscopic polypectomy is the most simple and safe method in removal of these polyps. We have underwent endoscopic snare polypectomy, strip biopsy and "O"ring ligation on upper gastrointestinal tract polyps in 274 lesions of 265 patients who visited in Pusan Paik hospital from July 1988 to December 1997, and the clinical characteristics including histopathology has been evaluated. The results obtained were as follows : 1) The age distribution of patients were from 28-year old to 78-year old. The ratio of male to female was 1:1.45. 2) The common clinical symptoms presented were epigastric discomfort (38.4%), epigastric pain (28.1%) and indigestion (19.6%). 3) The number of patient wish single gastric polyp was 225(85%), and that of multiple gastric polyps was 40(15%). 4) The most common location of gastric polyps was antrum(47.2%) and followed by body(37.5%) and fungus(9.1%). 5) The removed polyps were mostly 0.5∼1cm(44.8%) in size and in the gross findings by Yamada classifications type II(41.9%) was most common. 6) Histological examinations of gastric polypoid lesions revealed that 63.1% of removed polyps were hyperplastic polyps and 24% of 7hose were adenomatous polyps. 7) Almost all cases showed no significant complication, but there were postpolypectomy abdominal pain in 20 cases(7.5%) and minor bleeding in 8 cases(3.0%). Finally, we concluded that endoscopic polypectomy is a safe and relatively simple procedure and postpolypectomy complication can be considerably reduced by conservative antiulcer therapy, So. most of polypoid lesions of upper gastrointestinal tract should be removed and meticulous pathological review is mandatory.

      • 부산 지역 기관지천식 환자의 MAST 검사 결과

        오용창,임원준,석욱,주남영,정용학,김명준,우종길,박순규 대한천식알레르기학회 1997 천식 및 알레르기 Vol.17 No.4

        Objectives: Allergen is closely related with local features and cultural environment and a new apporach method regarding causes triggering aggravation is especially required due to complex and variety of ordinary residence and pollution of living environment recently. We, therefore, performed this study to inspire the necessity of identification of causative afeuts in aothmatic patiends in pusan area. Methods: We measured serum specific IgE antibody by means of chemiluminescent analyzer employing MAST, classified the level from class 0 to 4 and interpreted the result in order to ideutify allergen on total 262 patients consisted of inpatients and outpatients who had been presumed as extrinisic asthma and treated in this hospital during 2 and a half years from June of 1994 to December of 1996. Results: 1. With regard to sex and age distribution, the rate of men versus women was 1: 1.3, while in the distribution by age, the twenties and the thirties were the most as 29 % and 26% respectively. 2. The result of interpretation of the test showed positive in 75%, 78% of which showed positive reaction compounded of 2 kinds or more. 3. If we take a look at the distribution of total IgE class in the positive area, we can find that; Class 3 l and class Il showed the highest frequency as 47% and 37% respectively. 4. If we take a look at the distribution by age and allergen, the twenties(32% ) and the thirties(30%) showed the highest frequency, the fifities, the forties and the teens showed middle frequency as 10 13% and the sixties and the seventies showed the lowest frequency as about 1%. The causat ive allergen appeared in the order of pollen(40%), dust(20%), food(18 % ), fungus(13% ) and epidermis(8% ). 5. The distribution of allergen by season generally showed high rate of positive appearance in spring and fall as pollen appeared in spring(44%) and fall(27%), dust appeared in fall(32%) and summer(23%), food appeared in spring(34% ) and fall (29% ), fungus appeared in fall(.30% ) and spring(28% ) and epidermis appeared in spring(30%) and fall(28 %) 6. With regard to the allergen.' (1) In pollen allergens, trees showed higher positive frequency than weeds and trees were in the order of birch(14%), alder(13%) and hazelnut mix(12%) and weeds showed similar positive values. (2) In dust allergens, mite(D. pteronyssinus and D. farinae) showed high positive rate as 39% each. (3) In epidermal allergens, it also showed relatively even positive value among which cats hairdandruff was the highest as 40%. (4) In food allergens, shrimp showed the highest as 22 % and others were similar as evenly positive values. (5) In fungus allergens, Candida and Stemphylium showed the highest value as 19 % each. Conelusion: The analysis of allergen by means of MAST could be used as a valuable guide post for identifging cousative antigens for active treatment of extrinsic asthma.

      • KCI등재후보

        간조직내 HBV precore 변이를 동반한 HbeAg 양성 만성 B 형간염 환자에서의 인터페론 치료효과

        이연재(Youn Jae Lee),옥승철(Sung Cheul Ok),이상혁(Sang Hyuk Lee),설상영(Sang Young Seol),정정명(Jung Myung Chung),박영홍(Yeong Hong Park),주남영(Nam Young Joo) 대한내과학회 1998 대한내과학회지 Vol.55 No.1

        N/A type, Group 2: mixed) were received 3-6 MU INF three times a week for 4-6 months, We did follow-ups for at least six months(mean : Group 1-11.3, Group 2- 13.7 months). A complete responder was defined as persis- tent(>6 months) normalization of transaminase and loss of HBeAg and/or seroconversion. Results : The HBV precore mutants were found in 15 cases(31.2%) among 48 patients: 7 cases(21.2%) in 33 HBeAg-positive patients and 8 cases(53.396) in 15 HBeAg-negative patients. The HBV precore mutants were more frequently found in HBeAg-negative patients(p= 0.043). Differences in severity of hepatic pathology were not observed in the wild-type versus mutant-type chronic hepatitis B patients(p =1.00). Initial response rate was not significantly different between two Groups(p= 0.228), but complete response rate had a lower tendency in Group 2 (p=0.073). Conclusion : There is a tendency for HBV precore mutants to be less responsive to INF therapy than wild type. Therefore the patients with chronic hepatitis B should be treated as early as possible in natural history of their liver disease before the emergence of HBV precore mutants.

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