고환에서 발생한 종자세포암의 폐전이 절제 − 1예 보고 −

조준우,박기성 대한흉부외과학회 2010 Journal of Chest Surgery (J Chest Surg) Vol.43 No.6

This is a report of successful management for pulmonary metastasis following chemotherapy in patient with testicular germ cell tumor. Postchemotherapy PET-CT was not uptake FDG in metastatic lesion. Pulmonary metastasectomy was performed, which is important to manage a residual postchemotherapy lung mass in testicular germ cell tumor for histological correlation with primary testicular lesion to select the patients who require subsequent chemotherapy. Our patient was well 6 months after operation, not carried out chemotherapy because of no viable tumor. 이 보고는 고환종자세포암 치료 후 폐전이를 폐절제술을 시행하여 성공적으로 치료한 증례이다. 항암치료 후 양전자방출단층촬영상 FDG의 유의한 섭취는 없었고 잔존종양을 원발 병소와 조직학적 비교를 위해 전이암을 제거하였다. 본 증례는 잔존종양에 생존세포가 관찰되지 않아 부가적인 항암치료는 시행하지 않았으며, 현재 술 후 6개월로 현재 재발이나 합병증 없이 잘 지내고 있다.

Near-Infrared Spectroscopy versus Transcranial Doppler-Based Monitoring in Carotid Endarterectomy

조준우,장재석 대한흉부외과학회 2017 Journal of Chest Surgery (J Chest Surg) Vol.50 No.6

Background: Proper monitoring of cerebral perfusion during carotid artery surgery is crucial for determining if a s hunt is n eeded. We c ompared the safety a nd r eliability o f near-infrared spectroscopy ( NIRS) w ith transcranial Doppler (TCD) for cerebral monitoring. Methods: This single-center, retrospective review was conducted on patients who underwent carotid endarterectomy (CEA) using selective shunt-based TCD or NIRS at Daegu Catholic University Medical Center from November 2009 to June 2016. Postoperative complications were the primary outcome, and the distribution of risk factors between the 2 groups was compared. Results: The medical records of 74 patients (45 TCD, 29 NIRS) were reviewed. The demographic characteristics were similar between the 2 groups. One TCD patient died within the 30-day postoperative period. Postoperative stroke (n=4, p=0.15) and neurologic complications (n=10, p=0.005) were only reported in the TCD group. Shunt usage was 44.4% and 10.3% in the TCD and NIRS groups, respectively (p=0.002). Conclusion: NIRS-based selective shunting during CEA seems to be safe and reliable for monitoring cerebral perfusion in terms of postoperative stroke and neurologic symptoms. It also reduces unnecessary shunt usage.

Mid-Term Results of Using the Seal Thoracic Stent Graft in Cases of Aortopathy: A Single-Institution Experience

조준우,장재석,이철호,황선현 대한흉부외과학회 2019 Journal of Chest Surgery (J Chest Surg) Vol.52 No.5

Background: The endovascular approach to aortic disease treatment has been increasingly utilized in the past 2 decades. This study aimed to determine the long-term results of using the Seal thoracic stent graft. Methods: We retrospectively reviewed the outcomes of patients who underwent thoracic endovascular aortic repair or a hybrid procedure using the Seal thoracic stent graft (S&G Biotech, Seongnam, Korea) from January 2008 to July 2018 at a single institution. We investigated in-hospital mortality and the incidence of postoperative complications. We also investigated the mid-term survival rate and incidence of aorta-related complications. Results: Among 72 patients with stent grafts, 15 patients underwent the hybrid procedure and 21 underwent emergency surgery. The mean follow-up period was 37.86±30.73 months (range, 0–124 months). Five patients (6.9%) died within 30 days. Two patients developed cerebrovascular accidents. Spinal cord injury occurred in 2 patients. Postoperative renal failure, postoperative extracorporeal membrane oxygenation support, and pneumonia were reported in 3, 1, and 6 patients, respectively. Stent-related aortic complications were observed in 5 patients (6.8%). The 1- and 5-year survival and freedom from stent-induced aortic event rates were 81.5% and 58.7%, and 97.0% and 89.1%, respectively. Conclusion: The use of the Seal thoracic stent graft yielded good mid-term results. Further studies are needed to examine the long-term outcomes of this device.

Traumatic Aortic Injury: Single-center Comparison of Open versus Endovascular Repair

조준우,권오춘,이섭,장재석 대한흉부외과학회 2012 Journal of Chest Surgery (J Chest Surg) Vol.45 No.6

Background: Conventional open repair is a suboptimal therapy for blunt traumatic aortic injury (BTAI) due to the high postoperative mortality and morbidity rates. Recent advances in the thoracic endovascular repair technique may improve outcomes so that it becomes an attractive therapeutic option. Materials and Methods: From August 2003 to March 2012, 21 patients (mean age, 45.81 years) with BTAI were admitted to our institution. Of these, 18 cases (open repair in 11 patients and endovascular repair in 7 patients) were retrospectively reviewed and the early perioperative results of the two groups were compared. Results: Although not statistically significant, there was a trend toward the reduction of mortality in the endovascular repair group (18.2% vs. 0%). There were no cases of paraplegia or endoleak. Statistically significant reductions in heparin dosage, blood loss, and transfusion amounts during the operations and in procedure duration were observed. Conclusion: Compared with open repair, endovascular repair can be performed with favorable mortality and morbidity rates. However, relatively younger patients who have acute aortic arch angulation and a small aortic diameter may be a therapeutic challenge. Improvements in graft design, delivery sheaths, and graft durability are the cornerstone of successful endovascular repair.

Selective Carotid Shunting Based on Intraoperative Transcranial Doppler Imaging during Carotid Endarterectomy: A Retrospective Single-Center Review

조준우,전윤호,배지훈 대한흉부외과학회 2016 Journal of Chest Surgery (J Chest Surg) Vol.49 No.1

Background: Carotid endarterectomy (CEA) with selective shunting is the surgical method currently used to treat patients with carotid artery disease. We evaluated the incidence of major postoperative complications in patients who underwent CEA with selective shunting under transcranial Doppler (TCD) at our institution. Methods: The records of 45 patients who underwent CEA with TCD-based selective shunting under general anesthesia from November 2009 to June 2015 were reviewed. The risk factors for postoperative complications were analyzed using univariate and multivariate analysis. Results: Preoperative atrial fibrillation was observed in three patients. Plaque ulceration was detected in 10 patients (22.2%) by preoperative computed tomography imaging. High-level stenosis was observed in 16 patients (35.5%), and 18 patients had contralateral stenosis. Twenty patients (44.4%) required shunt placement due to reduced TCD flow or a poor temporal window. The 30-day mortality rate was 2.2%. No cases of major stroke were observed in the 30 days after surgery, but four cases of minor stroke were noted. Univariate analysis showed that preoperative atrial fibrillation (odds ratio [OR], 40; p=0.018) and ex-smoker status (OR, 17.5; p=0.021) were statistically significant risk factors for a minor stroke in the 30-day postoperative period. Analogously, multivariate analysis also found that atrial fibrillation (p<0.001) and ex-smoker status (p=0.002) were significant risk factors for a minor stroke in the 30-day postoperative period. No variables were identified as risk factors for 30-day major stroke or death. No wound complications were found, although one (2.2%) of the patients suffered from a hypoglossal nerve injury. Conclusion: TCD-based CEA is a safe and reliable method to treat patients with carotid artery disease. Preoperative atrial fibrillation and ex-smoker status were found to increase the postoperative risk of a small embolism leading to a minor neurologic deficit.

Moderate and Deep Hypothermia Produces Hyporesposiveness to Phenylephrine in Isolated Rat Aorta

조준우,이철호,장재석,권오춘,노운석,김정은 대한흉부외과학회 2013 Journal of Chest Surgery (J Chest Surg) Vol.46 No.6

Background: Moderate and severe hypothermia with cardiopulmonary bypass during aortic surgery can cause some complications such as endothelial cell dysfunction or coagulation disorders. This study found out the difference of vascular reactivity by phenylephrine in moderate and severe hypothermia. Methods: Preserved aortic endothelium by excised rat thoracic aorta was sectioned, and then down the temperature rapidly to 25oC by 15 minutes at 38oC and then the vascular tension was measured. The vascular tension was also measured in rewarming at 25oC for temperatures up to 38oC. To investigate the mechanism of the changes in vascular tension on hypothermia, NG-nitro-L-arginine methyl esther (L-NAME) and indomethacin administered 30 minutes before the phenylephrine administration. And to find out the hypothermic effect can persist after rewarming, endothelium intact vessel and endothelium denuded vessel exposed to hypothermia. The bradykinin dose-response curve was obtained for ascertainment whether endothelium-dependent hyperpolarization factor involves decreasing the phenylnephrine vascular reactivity on hypothermia. Results: Fifteen minutes of the moderate hypothermia blocked the maximum contractile response of phenylephrine about 95%. The vasorelaxation induced by hypothermia was significantly reduced with L-NAME and indomethacin administration together. There was a significant decreasing in phenylephrine susceptibility and maximum contractility after 2 hours rewarming from moderate and severe hypothermia in the endothelium intact vessel compared with contrast group. Conclusion: The vasoplegic syndrome after cardiac surgery might be caused by hypothermia when considering the vascular reactivity to phenylephrine was decreased in the endothelium-dependent mechanism.

국내 과수화상병을 부분 방제한 배와 사과 과원의 관리 현황 조사

조준우,노은정,이용환,김성환 한국식물병리학회 2023 식물병연구 Vol.29 No.3

최근 국내의 과수화상병 방제 정책이 매몰 방제에서 더하여부분적 방제가 시행되고 있다. 본 연구는 부분방제의 효율적추진을 모색하고자 2019년에서 2020년 사이 부분 방제를 시행된 과원에 대한 현장 관리상태 조사를 수행하였다. 천안과 충주지역 소재 22곳 배와 사과 과원 대한 조사 결과 7개 과원이매몰하였다. 절단한 감염주의 상부를 태운 과원은 16곳, 석회처리 후 커버를 씌운 과원은 6곳이었다. 절단한 감염주의 하부 그루터기를 태운 과원은 7곳, 커버를 씌운 과원은 15곳이었다. 커버를 씌웠어도 그루터기에 맹아가 발생한 과원은 2곳이었다. 맹아에 화상병균 감염은 없었다. 석회처리 상태는 양호하였으나경고 표지판이 부재한 곳이 6곳이었다. 대부분 과원이 그루터기와 주변에 glyphosate-isopropylamine 제초제를 처리하였다. 부분방제의 처리 결과는 대체로 안전한 것으로 판단되었다. Recently, the domestic plant disease control policy for fire blight has been implemented partial control in addition to burial control. In this study, an on-site management survey was conducted targeting orchards that implemented partial disease control from 2019 to 2020 in order to find efficient implementation methods for partial disease control. As a result of an investigation into 22 pear and apple orchards in Cheonan and Chungju, 7 orchards were buried. The upper part of the cut infected plants was burned at 16 orchards and covered with plastic vinyl after lime treatment at 6 orchards. The lower stumps of cut infected plants were burned at 7 orchards and covered with plastic vinyl after lime treatment at 15 orchards. There were two orchards where suckers appeared on the stumps even though covers were applied. There was no infection by Erwinia amylovora in the suckers. The conservation condition of lime treatment was good, but warning signs were absent at 6 orchards. Most orchards treated the stumps and surrounding areas with glyphosate-isopropylamine herbicide. The effect of partial control was judged to be safe.

ATP 측정기를 이용한 종이 표면의 세균 오염 평가

조준우,노형진,안금란,김준영,김성환 한국냄새환경학회 2023 실내환경 및 냄새 학회지 Vol.22 No.3

ATP luminescence measurements (using Relative Light Units, RLU) has been used to assess the levels of bacterial contamination on the surfaces of various materials. However, not much is known about their suitability in assessing bacterial contamination on paper surfaces. This study was conducted to evaluate the feasibility of using ATP luminometers in measuring levels of bacteria contamination on paper surfaces. The three ATP luminometers studied were Clean-Q, smart PD-30, and 3M™ Clean-Trace™ LM1 manufactured by different companies. There were some differences in RLU results among the three ATP luminometers when they were tested with different concentrations of Micrococcus luteus cell suspension. 106 - 107 cells were required in order to effectively detect Bacillus subtilis, Escherichia coli, and Micrococcus luteus on the surfaces of A4 printing sheets (100 cm2 ) when using the three ATP luminometers. The sizes and physical properties of surface areas varied slightly among the swabs used for the three ATP luminometers. Concentration-specific measurements (RLU) of M. luteus taken from the surfaces of six kinds of paper (fine print paper, medium print paper, ground paper, newsprint paper, practice paper, tracing paper) were possible using the smart PD-30 and LM1 ATP luminometers. ATP detection values of M. luteus varied among the six types of paper. The highest ATP detection values were found on the surfaces of tracing paper. If the RLU value is recorded at the level of 1000, this could indicate a very high bacterial contamination level of 105 to 106 CFU/4 cm.

Hierarchical Bayesian modeling with skew normal distribution

조준우,조길호,김용구 한국데이터정보과학회 2024 한국데이터정보과학회지 Vol.35 No.1

In fact, most statistical surveys consist of sample surveys, not total surveys. This paper considers the Bayesian hierarchical modeling for estimation in surveys with non-sample. In our study, there are two different surveys and the variables of interest consist of skewed values. For this problem, we first use a matching algorithm for two surveys and then develop a Bayesian hierarchical model with skew normal distribution and noninformative priors. Bayesian hierarchical models have been widely used for small area estimation. The Bayesian hierarchical model is based on a very simple model, and can be set up using a very complex data model. The paper by Molina, Nandram, and Rao (2014) introduces a Bayesian hierarchical model of continuous, right-skewed data. In this study, skewed variables were estimated using log transformation, and our purpose is to develop the previous method using skew normal distribution for model assumptions. Skew normal distribution, a family of distributions including the standard normal but with an extra parameter to regulate skewness was first introduced by O'Hagan and Leonard(1976). Our model was evaluated by comparing with Nandram's model in simulation study.

우주/공중 기반 기동통신망 핵심기술

조준우,오지훈,김동현,이재문,김재현 한국통신학회 2016 정보와 통신 Vol.33 No.11

네트워크 중심전의 승패는 전장 정보의 신속한 수집과 정보전송 능력에 달려 있으며, 이를 위해 무인기를 포함한 기동통신망의 중요성이 대두되고 있다. 본 고에서는 우주/공중 기반 기동통신망의 운용 동향에 대해 살펴보고, 우주/공중 기반 기동통신망 구조 설계와 함께 기동통신망에 적용 가능한 통신 기술에 대해 살펴본다.