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저자들은 아직 국내에 보고된 적이 없는 S. typhi에 의한 척추골수염 환자에서 ciprofloxacin을 5주간 투여하여 임상적 호전을 보였던 증례를 경험하였기에 보고하는 바이다. Vertebral osteomyelitis by Salmonella infection is rare. Although it is known to be associated with sickle cell anemia, various hemoglobinopathies and immunosuppressive states, it may also occur in normal host. To date, vertebral osteomyelitis with Salmonella. typhi has not been reported in Korea. We experienced a case of spinal osteomyelitis due to S. typhi in a 48-year old man who was admitted because of low back pain for two months. MRI scan showed vertebral osteomyelitis in L1 & L2. Needle aspiration was performed by CT guidance. S. typhi was identified from aspirated pus. However, any organism was not identified from blood and urine cultures. He was treated with ciprofloxacin for 5 weeks successfully.
Since the motion of the charged particle strongly depends on its charge characteristics, information on charge distributions of target particles is one of the important variables in aerosol research. In this study, charged distribution of atomized NaCl particles were measured using a Gerdien type ion counter. Two kinds of particle charging conditions were used in this study. First, atomized NaCl particles were passed through an aerosol neutralizer to have a Boltzmann charge distribution, and then its charge distribution was measured. In this case, the portion of uncharged particles was compared with the portion obtained from the Boltzmann charge distribution for verifying the suggested experimental method. Second, same experiment was conducted without the aerosol neutralizer to measure the charge distribution of atomized and un-neutralized NaCl particles. In the conclusion, the portion of uncharged, negatively charged and positively charged particles were 19%, 62% and 20%, respectively, for neutralized particles. The atomized particles, which was generated without the aerosol neutralizer, also had almost a zero charge state, but the standard deviation in charge distribution was larger than that of neutralized particles. The test method proposed in this study is expected to be used in various aerosol research fields because it can obtain simple information on the particle charge characteristics more easily and quickly than the existing test methods.
In this study, the clean air delivery rate (CADR) of ceiling air circulator (CAA) was determined under indoor environmental simulation conditions. An air filter was used to provide air cleaning ability to the CAA. The CADR of filter adapted CAA was evaluated and compared with the value of commercial air purifier. The installation of mesh-shaped filter on the CAA showed particle reduction effect on the particles over 0.4 μm in diameter, but the CADR was up to 0.25 m 3/min. When the filter having 99.9% in collection efficiency was installed on the CAA, its CADR was 1.52 m 3/min, while the CADR of commercial air purifier was 3.19 m 3/min.
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In this study, an enthalpy exchanger was coated by silver nano particles via spark discharge method and its antimicrobial and heat exchange efficiencies were evaluated. A method utilizing thermophoretic force was used to improve coating efficiency. Four spark discharge systems were parallel connected and generated silver nano aerosol particles (number concentration of 1.65×108 particles/cc, mode diameter of 31 nm). The coating efficiency was evaluated according to various face velocities (V=0.25~1 m/s) and temperature gradients ((Thot-Tcold)/Thot=0~0.09). The maximum coating efficiency was 90.8 % when the face velocity was 0.25 m/s and the temperature gradient was 0.09 (Thot=30℃, Tcold=2℃). Silver nano particles were coated onto the enthalpy exchange element and two different coating amounts of silver nano particles (0.11㎍/㎠, 0.22㎍/㎠) were tested. For evaluation of antimicrobial efficiency, the suspension test method with E. coli was used. After the suspension test method, CFU(colony forming unit)s of each test sample were counted and colony ratio was calculated. The colony ratio was decreased more quickly when the amount of coated silver particles was increased. When the contact time between each sample and suspension was over 3 hours, antimicrobial efficiencies of coated samples were more over 99.9 % for both amount of silver nano particle(0.11㎍/㎠, 0.22㎍/㎠). The coating of silver nano particles did not affect the heat exchange efficiency.