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조아진,박혜인,김도형,최한별,송기현,김현숙,김석형,최광호,김좌경,송영림,윤종우,이영기 대한신장학회 2023 Kidney Research and Clinical Practice Vol.42 No.1
Background: Plastic cannulae have attracted increasing interest as an alternative to traditional metal needles with the aim of reducingcannulation-related complications. We investigated whether the substitution volumes during hemodiafiltration differ using thesetwo types of needles in dialysis patients.Methods: An intervention study involving 26 hemodialysis patients was conducted in Korea between March and September in 2021.Patients first received online hemodiafiltration using traditional metal needles, and thereafter plastic cannulae were used in a stepwiseprotocol. Repeated-measures design and linear mixed-effect models were used to compare substitution volumes between thetwo needle types with the same inner diameter.Results: The mean patient age was 62.7 years, and their mean dialysis vintage was 95.2 months. Most patients (92.3%) had an arteriovenousfistula as the vascular access. The substitution volume increased as blood flow and needle size increased for both plasticcannulae and metal needles. The substitution volume was significantly higher with 17-gauge (G) plastic cannulae than with 16-G metalneedles at blood flow rates of 280, 300, and 330 mL/min. Similar results were obtained for 15-G metal needles and 16-G plasticcannulae at a blood flow rate of 330 mL/min. However, the patient ratings of pain on a visual analogue scale were higher for plasticcannulae.Conclusion: Higher substitution volumes were obtained at the same prescribed blood flow rate with plastic cannulae than with metalneedles during online hemodiafiltration. Plastic cannulae are an option for achieving high-volume hemodiafiltration for patients withlow blood flow rates.
순환신경망을 활용한 제조 공정 과정상의 오류 검출 방법 사례 연구
조아진,남혜림,조준,황종운,이용오 대한산업공학회 2018 대한산업공학회 추계학술대회논문집 Vol.2018 No.11
In this paper, we propose an error detection method on manufacturing process using Recurrent Neural Network (RNN) in order to overcome the limitation on time-based maintenance method still used in a majority of factories. Using RNN, errors in manufacturing process can be detected by manners of a preventive maintenance with a reliable accuracy.
조아진,최명진,이영기,한채훈,구자룡,윤종우,노정우 대한내과학회 2019 The Korean Journal of Internal Medicine Vol.34 No.6
Background/Aims: Maintaining the patency of vascular access (VA) in hemodialysis (HD) patients is important and can be life-saving. We investigated the effects of aspirin resistance and mean platelet volume (MPV) on VA failure in HD patients. Methods: We enrolled 163 patients on maintenance HD. VA failure was defined as thrombosis or a decrease of > 50% of the normal vessel diameter, as revealed by angiography. Results: Aspirin resistance was observed in 17 of 109 patients in whom this parameter was measured, and was not significantly associated with VA failure (p = 0.051). The mean MPV was 9.15 ± 0.05 fL. The 163 patients were grouped by the median MPV value (9.08 fL) at baseline; patients with higher MPVs (n = 82) had lower platelet counts (p = 0.002) and albumin levels (p = 0.009). During 34 months of follow-up, 65 VA failures (39.9%) occurred. The Kaplan-Meier curve revealed significant differences between the two groups in terms of cumulative VA failure (54.1% vs. 35.3%, p = 0.018). On multivariate analysis, the MPV (hazard ratio [HR], 1.794; 95% confidence interval [CI], 1.066 to 3.020; p = 0.028), platelet count (HR, 1.003; 95% CI, 1.001 to 1.006; p = 0.01), and smoking status (HR, 1.894; 95% CI, 1.019 to 3.519; p = 0.043) independently predicted VA failure. Conclusions: A high MPV was associated with an increased risk of VA failure, whereas aspirin resistance showed only a weak association. The MPV may predict VA survival in HD patients.