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양격산화탕(凉隔散化湯)이 Allergy성(性) 접촉피부염(接觸皮膚炎)에 미치는 영향(影響)
조세왕,Cho, Se-Wang 대한한방피부미용학회 2005 대한한방피부미용학회지 Vol.1 No.1
Objective : To study the effectiveness of Yangkyuksanhawtang against Allergic Contact Dermatitis I observed the change of cutaneous shape, histochemistry, immunohistochemistry, and the distribution of apoptotic cells. materials and methods : I divided 4-month-old rats into three groups of 10, which are a contrastive group of having applied Acetone olive oil only, ACD group to have intentionally activated Allergic Contact Dermatitis by DNCB and YST group to give medication of Yangkyuksanhawtang extract. And I observed each group of mice after 24, 48 and 72 hours. results : 1. With the result of Contact hypersensitivity assay, YST group shows appreciably less ear swelling than ACD group. 2. Comparing YST and ACD groups to each other regarding general change of skin, YST group shows less hyperplasia of epidermis, less migration of inflammatory cells and less damage of epidermis than ACD group. 3. Regarding the change of collagen fiber, ACD group has appeared to be low in number of collagen fiber while YST shows similarity with the contrastive group. 4. In dermis YST group has showed lower number of mastocyte than ACD group and is granulated type. 5. In dermis YST group has showed less MAC-1, IL-1 , $IL-2R-\;{\alpha}$ G, ICAM-1 and VCAM-1 than ACD group. 6. The distribution of apoptotic cells has appeared littler in YST group than in ACD 7. Among signal molecule of apoptosis Bcl-2 has distributed more in YST group than ACD group and Bax and Fas has distributed less in YST group than ACD group.
양격산화탕(凉隔散火湯)이 Allergy성(性) 접촉피부염(接觸皮膚炎)에 미치는 영향(影響)
조세왕,박성식,Cho, Se-wang,Park, Seong-sik 사상체질의학회 2001 사상체질의학회지 Vol.13 No.3
1. The purpose of study To study the effectiveness of Yangkyuksanhawtang(YST) against Allergic Contact Dermatitis(ACD) I observed the change of cutaneous shape, histochemistry, immunohistochemistry, and the distribution of apoptotic cells. 2. The material and method of study I divided 4-month-old rats into three groups of 10, which are a contrastive group of having applied Acetone olive oil only, ACD group to have intentionally activated Allergic Contact Dermatitis by DNCB and YST group to give medication of Yangkyuksanhawtang extract. And I observed each group of mice after 24, 48 and 72 hours. 3. The result and conclusion of study The change of cutaneous shape and hypersensitive reaction of immunity was significantly decreased by YST in ACD rats. I consider that YST suppressed hypersensitive reaction of immunity and inflammation in ACD.
은행잎 추출의약품으로 유발된 약진(藥疹)을 소음인(少陰人) 곽향정기산(藿香正氣散)으로 치료한 치험 1례
박성식,조세왕,Park, Seong-Sik,Cho, Se-Wang 사상체질의학회 2003 사상체질의학회지 Vol.15 No.2
Drug Eruption refers to an adverse effect which is unintentionally given rise to by dosage, injection, inhalation, suppository and ointment, etc. Hereby this report is about a remedial value of Gwaghyangjungkisan which was prescribed for a 78 year-old male featuring Soeumin who had suffered from papular eruption after taking a medicine composed of extract of gingko leaves.