골형태형성단백질 및 상피성장인자가 치주조직 재생에 미치는 영향

조성훈,권영혁,이만섭,허익,Cho, Seong-Hoon,Kwon, Young-Hyuk,Lee, Man-sup,Heer, Yeek 대한치주과학회 2000 Journal of Periodontal & Implant Science Vol.30 No.3

The 3 beagle dogs aged over one and half years and weighed 14 to 16 Kg were utilized in this study. Horizontal furcation defects were induced around 3rd, and 4th premolars bilaterally. BMP-4 in conjunction with EGF and BMP-4 only were applied in the right and left premolars respectively. 1 animal was sacrificed at 2nd week, 4th week, and 8th week, after regenerative surgery respectively. Semi-thin sections using glass-knife were stained with hematoxylin- eosin and trichrome for light microscopic study. The results were as follows : 1 . The long junctional epithelial downgrowth was observed in both area applied with BMP-4 and with BMP-4 and EGF at 2nd week after the surgery. 2 . The extensive regeneration of new bone and cementum was appeared at 4th week and the maturation of bone was observed at 8th week in both area applied with BMP-4 and with BMP-4 and EGF. 3 . The root ankylosis and resorption was presented along the exposed root surface at the coronal 1/3 of defect in the BMP-4 applied site, but it was not shown in the site applied with BMP-4 in conjunction with EGF at the 4th week. At 8th week, the root ankylosis was apparently appeared in the BMP-4 and EGF applied site as well as in the BMP-4 applied site. 4 . The periodontal ligament tissue including Sharpey's fiber inserted into cementum and alveolar bone, was formed along the exposed root surface in the area applied with BMP-4 only, but in the site applied with BMP-4 and EGF, the collagen fiber running parallel to the root surface without Sharpey's fiber, was observed in the periodontal ligament space at 4th and 8th week. Within the above results, BMP-4 had the remarkable capability to regenerate the periodontal tissue and EGF had possibility to prevent from the root ankylosis. Therefore, growth factors including BMP-4 and EGF may have the strong possibility to be utilized in the clinical periodontal treatments.

초음파 화학 반응을 이용한 WO_x 도핑 TiO₂ 광촉매 나노 분말의 합성

조성훈,이수완,Cho, Sung-Hun,Lee, Soo-Wohn 한국재료학회 2011 한국재료학회지 Vol.21 No.2

Nano-technology is a super microscopic technology to deal with structures of 100 nm or smaller. This technology also involves the developing of $TiO_2$ materials or $TiO_2$ devices within that size. The aim of the present paper is to synthesize $WO_x$ doped nano-$TiO_2$ by the Sonochemistry method and to evaluate the effect of different percentages (0.5-5 wt%) of tungsten oxide load on $TiO_2$ in methylene blue (MB) elimination. The samples were characterized using such different techniques as X-ray diffraction (XRD), TEM, SEM, and UV-VIS absorption spectra. The photo-catalytic activity of tungsten oxide doped $TiO_2$ was evaluated through the elimination of methylene blue using UV-irradiation (315-400nm). The best result was found with 5 wt% $WO_x$ doped $TiO_2$. It has been confirmed that $WO_x-TiO_2$ could be excited by visible light (E<3.2 eV) and that the recombination rate of electrons/holes in $WO_x-TiO_2$ declined due to the existence of $WO_x$ doped in $TiO_2$.

기관절개술 후 발생한 기도 협착에서 실리콘 기관 T tube 삽입술의 치료 효과

조성훈,이용만,오천환,Cho, Sung-Roon,Lee, Yong-Man,Oh, Cheon-Rwan 대한기관식도과학회 2007 大韓氣管食道科學會誌 Vol.13 No.2

Background and Objectives: Most of tracheal stenosis is resulted from longstanding endotracheal tube insertion. Treatments of tracheal stenosis are divided conservative and reconstructive treatment. The propose of this study was to evaluate the effect of prosthetic tracheal T-tube insertion on tracheal stenostic patients who can not be operated invasive surgery. Subjects and Method : Nine prosthetic tracheal T-tube insertion were studied from 9 patients from January 2002 to April 2007. The effect of silastic T-tube was analyzed according to the factors that were respiratory difficulty, oxygen saturation, phonation, aspiration and significant complications. Results: Four patients were good for respiration and no complication. But five patients occur various complications. A successful group did not have cartilagenous lesions but failed group had catilagenous lesions, infection and necrosis. Conclusion: A silastic T-tube insertion was good for palliative treatment in patients without catilagenous lesions.

실리콘 산화질화물 기지상 적용에 따른 Au 나노입자 분산 복합체 박막의 광학적 특성

조성훈,이경석,Cho, Sung-Hun,Lee, Kyeong-Seok 한국재료학회 2009 한국재료학회지 Vol.19 No.12

In this study, we analyzed the effect of silicon oxynitride matrix on the optical properties of Au nanoparticles dispersed on composite film and explored the effectiveness of the silicon in fine tuning the refractive index of the composite film for applications in optical waveguide devices. The atomic fraction of nitrogen in $SiO_xN_y$ films was controlled by varying the relative flow ratio of nitrogen gas in reactive sputtering and was evaluated optically using an effective medium theory with Bruggeman geometry consisting of a random mixture between $SiO_2$ and $Si_3N_4$. The Au nanoparticles were embedded in the $SiO_xN_y$ matrix by employing the alternating deposition technique and clearly showed an absorption peak due to the excitation of surface plasmon. With increasing nitrogen atomic fraction in the matrix, the surface plasmon resonance wavelength shifted to a longer wavelength (a red-shift) with an enhanced resonance absorption. These characteristics were interpreted using the Maxwell-Garnett effective medium theory. The formation of a guided mode in a slab waveguide consisting of 3 $\mu$m thick Au:$SiO_xN_y$ nanocomposite film was confirmed at the telecommunication wavelength of 1550 nm by prism coupler method and compared with the case of using $SiO_2$ matrix. The use of $SiO_xN_y$ matrix provides an effective way of controlling the mode confinement while maintaining or even enhancing the surface plasmon resonance properties.

메타데이타의 생성 및 관리를 위한 RDF 문서 검증기와 N-Triple 생성기

조성훈,송병열,조현규,최의인,Cho, Sung-Hoon,Song, Byoung-Youl,Cho, Hyun-Gyu,Choi, Eui-In 한국정보처리학회 2004 정보처리학회논문지B Vol.11 No.5

전자상거래가 활성화됨에 따라 웹 상에서 공유되는 기업 정보와 카탈로그(catalog) 같은 비즈니스 정보의 양이 급속도로 증가하였다. 이를 효율적으로 처리하고자 RDF 메타데이타 프레임워크를 이용한 메타데이타의 관리 필요성이 대두되었다. RDF 메타데이타의 관리는 RDF/RDFS의 지식에 대해 제약받지 않고 웹 자원을 기술할 수 있어야 하고 메타데이타의 유효성을 보장하기 위한 환경을 지원하여야 딴다. 그러나 이를 적절히 지원할 수 있는 연구가 아직까지 미흡한 상황이다. 이를 위해 본 논문에서는 RDF/RDFS 문서를 다양한 인터페이스를 통해 생성 및 관리가 가능하며, RBF를 이용하여 기술된 메타데이타를 N-Triple로 제공함과 동시에 메타데이타의 유효성 검증이 가능하도록 하였다. The quantity of business information like to be shared enterprise information and business catalog quickly increased because of activating e-commerce. Necessary of metadata management which is using RDF was required. RDF metadata management does not have to be restricted by RDF/RDFS knowledges, has to describe web resources and has to support metadata validation. But research which supports this is not enough. In this paper we enable to create and manage RDF/RDFS document using various interfaces, change from metadata to N-Triple and verify metadata validation.

Market Equilibrium and Spatial Variability in the Value of Housing Attributes

조성훈,김승규,Cho, Seong-Hoon,Kim, Seung Gyu 한국환경경제학회 2009 자원·환경경제연구 Vol.18 No.2

본 연구는 각각의 세분화된 부동산 시장에서 주택의 특성들이 시장 균형점을 찾을 수 있는지에 대한 가정을 실증 분석하였다. 주택의 건축 특성 등과 같이 공급 탄력적인 변수들은 주택의 주변 환경 등과 같은 공급 비탄력적인 변수에 비하여 시장 균형점에 더 가까운 것으로 나타났다. 또한, 주택 거주자의 평균 거주 기간으로 측정한 거주자의 이동 가능성이 높은 부동산 시장에서 공급 탄력적인 변수들이 공급 비탄력적인 변수들에 비해 시장 균형점에 더 가까운 결과를 보였다. 따라서 주택 시장에서 공급 탄력성과 거주자의 이동 가능성이 시장 균형점에 필요한 조건으로 파악되었다. The hypothesis that the common market equilibria for housing attributes are attained within distinctive submarkets was tested. Markets for housing attributes with greater supply flexibility, i.e., structural variables, were found to be closer to their common equilibria than markets with less supply flexibility, i.e., neighborhood and distance variables. In addition, submarkets with greater mobility were found to achieve common market equilibria for more housing attributes with greater supply flexibility, but not for housing attributes with lower degree of supply flexibility. Results suggest supply flexibility and occupier mobility are both necessary conditions for achieving common market equilibria for housing attributes.

초음파화학 반응에 의한 Ag 도핑 광촉매용 나노 TiO₂ 분말의 합성

조성훈,이수완,Cho, Sung-Hun,Lee, Soo-Whon 한국재료학회 2009 한국재료학회지 Vol.19 No.3

In chemistry, the study of sonochemistry is concerned with understanding the effect of sonic waves and wave properties on chemical systems. In the area of chemical kinetics, it has been observed that ultrasound can greatly enhance chemical reactivity in a number of systems by as much as a million-fold. Nano-technology is a super microscopic technology in which structures of 100 nanometers or smaller can be investigated. This technology has been used to develop $TiO_2$ materials and $TiO_2$ devices of that size. Thus far, electrochemistry methods and photochemistry methods have generally been used to create $TiO_2$ nano-size particles. However, these methods are complicated and create pollutants as a by-product. In the present study, nano-scale silver particles (5 nm) were prepared in a sonochemistry method. Sonochemistry deals with mechanical energy that is provided by the collapse of cavitation bubbles that form in solutions during exposure to ultrasound. $TiO_2$ powders 25 nm in size doped with Ag were formed using an ultrasonic sound technique. The experimental results showed the high possibility of removing pollution through the action of a photocatalyst. This powder synthesis technique can be considered as an environmentally friendly powder-forming processing owing to its energy saving characteristics.

데이터베이스 지식발견체계에 기반한 경영성과 정보시스템의 구축

조성훈,정민용,김종화,Cho, Seong-Hoon,Chung, Min-Yong,Kim, Jong-Hwa 대한산업공학회 2001 산업공학 Vol.14 No.2

We suggest a Business Performance Information System with Knowledge Discovery in Databases(KDD) as a key component of integrated information and knowledge management system. The proposed system measures business performance by considering both VA(Value-Added), which represents stakeholder's point of view and EVA(Economic Value-Added), which represents shareholder's point of view. In modeling of Business Performance Information System, we apply the following KDD processes : Data Warehouse for consistent management of a performance data, On-Line Analytic Processing(OLAP) for multidimensional analysis, Genetic Algorithms for exploring and finding dominant managing factors and Analytic Hierarchy Process(AHP) for applying expert's knowledge and experience. To demonstrate the performance of the system, we conducted a case study using financial data of Korean automobile industry over 16 years from 1981 to 1996, which is taken from database of KISFAS(Korea Investors Services Financial Analysis System).

백서 치아 발거후 잔존 치주인대가 발치와의 치조골 재건에 미치는 영향

조성훈,허익,박준봉,이만섭,권영혁,Cho, Seong-Hoon,Herr, Yeek,Park, Joon-Bong,Lee, Man-Sup,Kwon, Young-Hyuk 대한치주과학회 1995 Journal of Periodontal & Implant Science Vol.25 No.3

The purpose of this study was to observe the effects of the periodontal ligament on the healing and the formation of alveolar bone in the extraction socket, when this ligament had artificially remained in the socket during the tooth removal. Twenty rats aged 4 weeks were used and devided into the control groups (10) and the experimental groups (10) in this study. The maxillary right and left first molars were extracted in both groups. In the experimental groups the periodontal ligament was remained in the extraction sockets using 0.4% ${\beta}-aminopropionitrile$, and in the control the periodontal ligament was completely removed by curettage. At 1, 3, 5, 7 and 14 days after the tooth extraction, rats in both groups were serially sacrificed. And the specimens were prepared with Hematoxylin-Eosin stain for the light microscopic evaluation. The results of this study were as follows ; 1. On 1 day, the periodontal ligament was only found in the extraction socket walls of the experimental groups, and there was not the distinguishable difference between the control and the experimental groups. 2. On 3 days, there were more collagen fibers and the appearance of higher cellular density in the experimental groups than in the control. And the cells and collagen of the periodontal ligament were so actively proliferated and synthesized that invaded into the connective tissue of the extraction sockets in the experimental groups. 3. In the experimental groups, the trabecular bone was formed on the basal and lateral bone surface on 5 days. However, there was not the new bone forming appearance in the control groups at this time. 4. On 7 days, the trabecular bone was formed in the control groups. 5. On 14 days, the extraction sockets were almost entirely filled with the bony trabeculae in both groups. But, compared to the control group, the experimental groups showed the prominent differences in the amount & the density of the new bone formed. In conclusion, it was suggested that the residual periodontal ligament tissue in the extraction socket will play a major role as the important cell source in the healing and the new bone formation of the extraction socket.

신규 사용자 추천 성능 향상을 위한 가중치 기반 기법

조성훈,이무훈,김정석,김봉회,최의인,Cho, Sun-Hoon,Lee, Moo-Hun,Kim, Jeong-Seok,Kim, Bong-Hoi,Choi, Eui-In 한국정보처리학회 2009 정보처리학회논문지D Vol.16 No.2

오늘날 컴퓨팅 환경의 진보와 웹의 이용이 활발해짐에 따라 오프라인에서 이루어졌던 있었던 많은 서비스들과 상품의 제공이 웹에서 이루어지고 있다. 이러한 웹 기반 서비스 및 상품은 개인에 적합하게 취사선택되어 제공되는 추세이다. 이렇듯 개인에 적합한 서비스 및 상품의 선택과 제공을 위한 패러다임을 개인화(personalization)라 한다. 개인화된 서비스 및 상품의 제공을 위한 분야로서 연구된 것이 추천(recommendation)이다. 그러나 이러한 추천 기법들은 신규 사용자에게 적합한 추천을 제공하지 못하는 문제와 사용자의 상품에 대한 평점에만 의존하여 추천을 생성한다는 계산 공간에서의 제약 사항을 가지고 있다. 두 문제 모두 추천 분야에서 지속적인 관심을 보이는 분야로서 신규사용자 추천 문제의 경우는 신규 사용자의 평점이 없기 때문에 유사 사용자들을 분류할 수 없음에 기인한다. 그리고 추천 공간 제약에 따른 문제는 추천 차원의 추가에 따른 처리 비용이 급격히 증가한다는 문제를 가지고 있기 때문에 쉽게 접근하기 어렵다. 따라서 본 논문에서는 신규사용자 추천 향상을 위한 기법과 평점 예측 시 예측에 대한 가중치를 적용하는 기법을 제안한다. Today, many services and products that used to be only provided on offline have been being provided on the web according to the improvement of computing environment and the activation of web usage. These web-based services and products tend to be provided to customer by customer's preferences. This paradigm that considers customer's opinions and features in selecting is called personalization. The related research field is a recommendation. And this recommendation is performed by recommender system. Generally the recommendation is made from the preferences and tastes of customers. And recommender system provides this recommendation to user. However, the recommendation techniques have a couple of problems; they do not provide suitable recommendation to new users and also are limited to computing space that they generate recommendations which is dependent on ratings of products by users. Those problems has gathered some continuous interest from the recommendation field. In the case of new users, so similar users can't be classified because in the case of new users there is no rating created by new users. The problem of the limitation of the recommendation space is not easy to access because it is related to moneywise that the cost will be increasing rapidly when there is an addition to the dimension of recommendation. Therefore, I propose the solution of the recommendation problem of new user and the usage of item quality as weight to improve the accuracy of recommendation in this paper.