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        • KCI등재

          복부 및 사지 부위의 전기침 자극이 전두근에서 측정한 SEMG 변화에 미치는 영향 - 자율신경계의 변화에 대한 임상적 접근을 위한 사전 연구 -

          제준태,최산호,신선호,임진영,이상관,Je, Jun-Tae,Choi, San-Ho,Shin, Sun-Ho,Lim, Jin-Young,Lee, Sang-Kwan 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.1

          Objectives : To observe physiological changes during clinical acupuncture treatment. Methods : We recruited 40 healthy volunteers who had experienced an acupuncture treatment at least once within the past three years. The experimental group was divided into four groups according to the needling site and frequency of electrical stimulation. Sites consisted of abdomen and legs. Frequencies consisted of 100 Hz and 2 Hz. The procedures of experimental treatment consisted of seven phases, Resting I phase (Resting I), Needle insertion phase (Insertion), Maintenance of needle insertion I phase (Maintain I), Electrical stimulation phase (ES), Maintenance of needle insertion II phase (Maintain II), Needle removal phase (Removal) and Resting II phase (Resting II). We measured the surface electromygraphy (SEMG) through an electrode on the frontalis muscle during all phases consecutively. Results : When SEMGs of all seven phases were analyzed, they significantly increased or decreased according to phases. SEMGs of Insertion, Maintain I, ES and Maintain II phase significantly increased more than RestingI in abdomen and legs groups. SEMGs of the abdomen group were measured as being $4.78{\pm}0.74{\mu}V$ on Resting I, $16.48{\pm}3.97{\mu}V$ on Insertion, $46.31{\pm}10.56{\mu}V$ on Maintain I, $45.88{\pm}9.72{\mu}V$ on ES, $45.56{\pm}9.69{\mu}V$ on Maintain II, $18.76{\pm}3.05{\mu}V$ on Removal, and $3.75{\pm}0.65{\mu}V$ on Resting II. SEMGs of the legs group were measured as being $3.34{\pm}0.35{\mu}V$ on Resting I, $12.11{\pm}1.76{\mu}V$ on Insertion, $36.74{\pm}6.99{\mu}V$ on Maintain I, $33.57{\pm}6.30{\mu}V$ on ES, $32.66{\pm}6.03{\mu}V$ on Maintain II, $14.08{\pm}2.15{\mu}V$ on Removal, and $2.88{\pm}0.32{\mu}V$ on Resting II. Conclusions : SEMG changed differently according to processes of acupuncture. Electrical stimulation showed different change of SEMG. Thus, acupuncture treatment may change the status of the autonomic nervous system.

        • KCI등재

          뇌졸중 후 우울증에 대한 황련해독탕 약침의 안전성 및 유효성 평가를 위한 임상 시험

          제준태,이상관,Je, Jun-Tae,Lee, Sang-Kwan 대한약침학회 2010 Journal of pharmacopuncture Vol.13 No.2

          Objective : The purpose of this study is to determine the efficacy and safely of Hwangryunhaedok-tang Pharmacopuncture (HHT-PA) therapy on post-stroke depression (PSD) in stroke patients. Methods : Fifteen PSD patients has been recruited and evaluated with liver function test (LFT) and renal function lest (RFT) and depression scales, Beck Depress ion Inventory (BDI) and Hamilton Depression Rating Scale (HAM-D) before and after HHT-PA treatment. Results : HAM-D score significantly decreased after HHT-PA treatment regard less of improving of motor function. But BDI score did not decrease significantly. All results of LFT and RFT were in normal range before and after HHT-PA treatment Conclusion : These results showed that HHT-PA decrease PSD symptoms and has safety on stroke patients, although has no effect on improving of motor impairment.

        • KCI등재

          Effects of Electroacupuncture on Immobilization Stress Responses : A Study on Inhibitory Avoidance Task, Forced Swimming Test, and Stress Hormones

          권소연,김민수,이상관,제준태,오재건,이종덕,성강경,Kwon, So-Yeon,Kim, Min-Soo,Lee, Sang-Kwan,Je, Jun-Tae,Oh, Jae-Gun,Lee, Jong-Deok,Sung, Kang-Keyng The Society of Internal Korean Medicine 2011 大韓韓方內科學會誌 Vol.32 No.1

          목적 : 본 연구는 결박 스트레스를 시행한 백서의 기억력, 우울, 스트레스 호르몬의 혈중 농도에 대한 전기침의 효과를 관찰하였다. 재료와 방법 : 결박 그룹은 10일 동안 2시간의 결박 스트레스를 받았다. 결박 스트레스 및 고주파수 전침 그룹은 2시간의 결박 스트레스를 받는 동시에 100Hz의 전침을 우측 족삼리 (ST-36)에 시행하였다. 기억력과 우울에 미치는 결박 스트레스와 침의 효과를 비교하기 위하여 억제성 회피 과제와 강제 수영 검사를 실시하였다. 결박 스트레스 및 전기침으로 유도된 코르티코스테론과 멜라토닌, 부신피질자극호르몬, 노르아드레날린의 농도를 측정하기 위하여 결박 스트레스 및 전기침 자극이 시작된 30분, 60분, 90분, 120분 후에 백서의 꼬리에서 혈액 샘플을 채취하였다. 결과 : 억제성 회피 과제에서 전기침을 시행한 그룹은 시행하지 않은 그룹에 대해서 장기 기억의 증진에 유의한 변화가 있었다. 강제 수영 검사 결과에서는 우울에 유의한 변화가 없었으며, 스트레스 호르몬 반응 결과에서도 유의한 변화가 없었다. 결론 : 1. 고주파수 전기침 (100Hz)은 억제성 회피 과제 결과 결박 스트레스에 기억력을 상승시켰다. 2. 고주파수 전기침 (100Hz)은 강제 수영 시험 결과 결박 스트레스로 유도된 우울을 감소시키지 않았다. 3. 고주파수 전기침 (100Hz)은 혈액 채취 결과 스트레스 호르몬을 감소시키지 않았다. Objectives : This study investigated the effects of electroacupuncture on memory, depression, and plasma stress hormone levels in rats that were under immobilization stress. Materials and Methods : The immobilization-only group was given two hours of immobilization stress for 10 consecutive days. The immobilization and high frequency EA group was given two hours of immobilization stress simultaneously with high frequency (100Hz) electroacupuncture stimulation on the right ST-36 (Zusanli) for 10 consecutive days. We conducted the inhibitory avoidance and forced swimming tests to recognize whether immobilization stress and electroacupuncture have effects on memory and depression. We collected blood samples from the tail of each rat at 30, 60, 90, and 120-minute intervals during the immobilization stress and EA stimulation to measure plasma concentrations of ACTH, corticosterone, melatonin, and norepinephrine induced by immobilization stress and electroacupuncture. Results : There was a significant effect of high frequency on the increase in anamnesis based on the result of the inhibitory avoidance test, but there was no significant effect of decreasing depression based on the result of the forced swim test. Also, there was no significant effect on the response indicated by stress hormones. Conclusions : 1. High frequency electroacupuncture (100Hz) improved anamnesis in immobilization stress states under the inhibitory avoidance task. 2. High frequency electroacupuncture (100Hz) did not reduce depression induced by immobilization stress under the forced swimming test. 3. High frequency electroacupuncture (100Hz) did not decrease stress hormones through blood sampling.

        • SCOPUSKCI등재

          膈下逐瘀湯이 Diethylnitrosamine과 CCl<sub>4</sub>로 유발된 흰쥐의 肝癌 形成과 肝損傷에 미치는 영향

          허래경,성기문,김소연,제준태,권소연,문구,이종덕,원진희,Heo, Rae-Kyong,Seung, Kee-Moon,Kim, So-Yeon,Je, Jun-tae,Kwon, So-yeon,Moon, Goo,Lee, Jong-Deok,Won, Jin-Hee 대한약침학회 2009 Journal of pharmacopuncture Vol.12 No.4

          This study was performed to observe the effect of Keughachukeo-tang(KH) extract on the hepatocellular carcinogenesis and acute liver damage induced by Diethylnitrosamine(DENA) and $CCl_4$ in Rats. Experimental groups were divided into four; normal group(Nor), acute liver damage and hepatocellular cancer inducing control group(Con), KH extract 350㎎/㎏/day(KHA), and 700㎎/㎏/day(KHB) administered groups to Con. The results obtained are as follows: The body weight increased in KHA and KHB than Con from 7th week to the 8th week. The activities of Alanine aminotransferase(ALT) were the most increased in the Con among experimental group. The activities of aspartate aminotransferase(AST), alkaline phosphatase(ALP), and lactacte dehydrogenase(LDH) were significantly decreased(p$<$0.05) in the KHA and KHB compared with Con. Alpha fetoprotein(AFP) were the most increased in the Con among experimental groups. The activities of superoxide dismutase(SOD) were the most increased in the Con among experimental groups. The activities of catalase were significantly increased(p$<$0.05) in the KHA and KHB compared with Con. The results of light microscopical observation, a number of hepatocytes were damaged in the Con compared with Nor and KH extract administerd groups. The number of hepatic p53 positive cells was reduced in the KH extract administered groups compared with Con. These results suggest that administration of KH extract suppress or retard on the Hepatocellular Carcinogenesis and acute liver damage induced by DENA and $CCl_4$ in Rats.

        • KCI등재
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