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비강 림프종과 동반된 안구내 자연살해/T세포 림프종 추정 1예
정훈석,박상희,이재훈,이대영,남동흔,Hoon Seok Jeong,MD,Sang Hui Park,MD,Jae Hoon Lee,MD,PhD,Dae Yeong Lee,MD,Dong Heun Nam,MD,PhD 대한안과학회 2011 대한안과학회지 Vol.52 No.7
Purpose: To report a case of presumed intraocular natural killer/T-cell lymphoma (NKTL). Case summary: A 61-year-old male presented with visual disturbance of the left eye for duration of 3 years. He had been treated with systemic chemotherapy and radiotherapy for nasal NKTL 1 year prior. Inflammatory reaction in the anterior chamber and vitreous opacity were observed in the left eye. The patient was diagnosed with uveitis in the left eye at a local clinic 3 years prior to visiting us. Because the patient did not respond to anti-inflammatory therapy, we performed diagnostic and therapeutic vitrectomy. Intraoperatively, vitreous opacity was thin sheet like in appearance. The vitreous specimen contained few lymphoid cells and was positive for Epstein Barr virus-encoded RNA (EBER). Systemic workups showed no metastasis to other organs. The patient was treated with systemic methotrexate chemotherapy and intravitreal methotrexate injected 3 times (once per week). During the 12-month follow-up period after the last intravitreal injection, the recurrence of lymphoma and related uveitis was not observed. J Korean Ophthalmol Soc 2011;52(7):871-875
인천 지역에 거주하는 고령인구에서의 건성안 유병률 및 위험인자
정훈석,임정수,오대규,지미정,백혜정,신경환,김균형,Hoon Seok Jeong,Jung Soo Lim,Dae Kyu Oh,Mi Jung Chi,Hye Jung Paik,Kyung Hwan Shyn,Kyun Hyung Kim 대한안과학회 2011 대한안과학회지 Vol.52 No.10
Purpose: To investigate the prevalence, clinical manifestations, and risk factors of dry eye syndrome (DES) among people over 50 years old in the Incheon area. Methods: A cross-sectional prevalence study was performed on 462 people over 50 years old in Dong-gu, Incheon. DES was defined as the constant or frequent presence of symptoms of both dryness and irritation. Symptoms and past medical history were assessed by a survey. Eye examination included slit lamp examination, Schirmer test, and tear break-up time (T-BUT). Age, sex, living habits, systemic and eye diseases were also analyzed to determine the risk factors of DES. Results: The prevalence of DES was 26.2%. The major symptoms were as follows in descending order: dryness (77.9%), tearing (75.2%), and sandiness (72.7%). An average of 12.1 ± 6.0 mm in the Schirmer test and 6.7 ± 2.4 seconds in the T-BUT were significantly different in the DES group from the normal group (<em>p</em> < 0.001). Variables such as age, sex, living habits, and eye diseases were not related to the diagnosis of DES, whereas diabetes was the only risk factor of DES with statistical significance (<em>p</em> = 0.03). Conclusions: In the present study, the prevalence of DES among people over 50 years old in the Incheon area was 26.2%. Schirmer test and T-BUT were considered to be helpful tools for the diagnosis of DES, and diabetes was a significant risk factor of DES. J Korean Ophthalmol Soc 2011;52(10):1135-1141
정훈석,남동흔,백혜정,이대영 대한안과학회 2012 Korean Journal of Ophthalmology Vol.26 No.2
Purpose: To evaluate the efficacy and safety of a pars plana Ahmed valve implantation combined with 23-gauge sutureless vitrectomy in the treatment of patients with medically uncontrolled neovascular glaucoma (NVG) in proliferative diabetic retinopathy (PDR). Methods: The authors retrospectively reviewed the records of 11 consecutive patients with refractory NVG in PDR who underwent a 23-gauge sutureless vitrectomy combined with pars plana placement of an Ahmed valve implant. Control of intraocular pressure (IOP), pre- and postoperative best-corrected visual acuity and the development of intra- and postoperative complications were evaluated during the follow-up. Results: The mean follow-up was 12.2 months (range, 8 to 25 months). Mean preoperative IOP was 35.9 6.3mmHg and mean postoperative IOP at the last visit was 13.3 3.2 mmHg. Control of IOP (8 to 18 mmHg) was achieved in all patients, but 91% (10 of 11 patients) needed antiglaucoma medication (mean number of medications,1.2 0.6). Postoperative visual acuity improved in 11 eyes, and the logarithmically to the minimum angle of resolution mean visual acuity in these eyes improved from 1.67 0.61 to 0.96 0.67. The complications that occurred were transient hypotony in one case, transitory hypertension in two cases, and postoperative vitreous hemorrhage which spontaneously cleared in two cases. Conclusions: We suggest the combination of 23-gauge pars plana vitrectomy and Ahmed valve implantation is safe and effective in PDR patients with refractory NVG.