해양학과 해양한경공학의 관계

정회수 한국해양환경·에너지학회 2003 한국해양환경공학회 학술대회논문집 Vol.2003 No.-

A Glove Box for the Subsampling of Suboxic and Cold Core Sediment

정회수,권수재,김종근,JUNG, HOI-SOO,KWEON, SOO-JAE,KIM, CHONG-KUN The Korean Society of Oceanography 1990 韓國海洋學會誌 Vol.25 No.4

To solve two problems, temperature shock to the man and difficulty in exchanging the air in the glove box into N2 gas, during the subsampling of Suboxic and cold core sediments, a portable glove box with a refrigerating machine and a gas exchanging bag was constructed for subsampling of sediment cores on board. The refrigerator of the glove box can cool down 200 litter air at 30$^{\circ}C$ to 2$^{\circ}C$${\pm}$2$^{\circ}C$ within 5 minutes. The box was successfully operated during the second KORDI's deep sea research cruise of 1989 in the North equatorial Pacific. Pore water data obtained from the cruise show no evidence for artifacts caused by warming up or oxidation of sediments during subsampling.

한국 서해 천수만 선현세 간월도 퇴적층의 퇴적환경

정회수,엄인권,임동일,Jung, Hoi-Soo,Um, In-Kwon,Lim, Dong-Il 한국해양학회 2002 바다 Vol.7 No.1

한국 서해 천수만 조간대 퇴적체는 약 20m 두께에 달하며, 지난 빙하기동안 노출되어 형성된 부정합면을 경계로 상위의 현세 조간대 퇴적층(Unit M1)과 하위의 후기 플라이스토세 간월도층(Unit M2)으로 구성된다. 퇴적단위 M1은 간월도층을 하부층으로하는 부정합면 위로 니질의 상부 조간대층과 사니질 또는 니사질의 혼합 조간대층이 순차적으로 발달하는 상향조립화의 해침층서를 갖는다. 퇴적단위 M2 퇴적층은 그 두께가 약 14 m에 이르며, 퇴적후 노출에 의한 풍화의 정도에 따라 상부 산화대층과 하부의 비산화대층으로 구분된다. 전반적으로 퇴적물은 니질 또는 사니질 입자로 구성되며, 조수 리듬 퇴적구조, 플라저층리, 엽층리, 게 구멍 화석, 천해성 와편모조류 등과 같은 조수퇴적 기원의 증거들을 함유하고 있다. 이러한 결과들은 퇴적단위 M2의 간월도 퇴적층이 상대적으로 해수면이 높았던 선현세 간빙기 동안 퇴적된 조간대 퇴적층임을 지시한다. 한편, 퇴적단위 M2의 상부 3${\sim}$4 m는 퇴적 후 초기현세까지 계속되는 저해수면 동안 대기중에 노출되어 풍화 및 산화작용으로 인하여 퇴적물의 특성이 변질된 층으로 해석되며, 이는 서해 연안 퇴적층에서 현세와 선현세를 구분해주는 뚜렷한 층서적 건층으로 제시된다. The late Quaternary deposit of Cheonsu Bay, up to 20 m in thickness above the Jurassic granite basement, consists of two sedimentary units: an upper Holocene mud and sandy mud deposit (Unit M1), and a lower late Pleistocene sand and mud deposit (Unit M2; 'Kanweoldo Deposit&apos). Unit M1 is a typical Holocene tidal-flat deposit of Cheonsu Bay, showing a coarsening upward, retrogradational facies trend. This retrograding facies trend is probably due to a relative low sedimentation rate during Holocene transgression. Overlain unconformably by Unit M1, Unit M2 deposit reaches up to 14 m in thickness and is mainly composed of muddy sediment with yellow to gray color. This unit is characterized by a variety of tide-influenced signatures such as rhythmic bedding, flaser bedding, crab burrow fossil, marine dinoflagellate assemblage and authigenic glauconite mineral, indicating very similar depositional environment to those of Unit M1 deposit. It suggests that Unit M2 was probably accumulated under the tidal-flat environment during a pre-Holocene sea-level highstand. In particular, the uppermost 3-4 m of Unit M2 appears to have undergone subaerial exposure and subsequent weathering during the sea-level lowstand after deposition. Therefore, stratigraphic unconformity between Holocene and late Pleistocene sediments is highlighted by the desiccated and weathered surface of Unit M2.

KODOS-89 지역 표층의 황색 퇴적물과 그 하부 갈색 퇴적물의 지구화학적 특성

정회수,강정극 한국해양학회 1991 韓國海洋學會誌 Vol.26 No.3

KODOS (Korea Deep ocean Study)-89 sediments, recovered from western part of Clarion-Clipperton fracture zone in north Pacific, show two distinctly colored layer zones: surface yellow brown layer (unit A) and subsurface dark brown layer (unit B), and roughly recognized as Quaternary and Tertiary in age, respectively. Geochemical characteristics are also different in those two units. Smectite, water, micronodule, and heavy metal contents are higher in unit B, while POC content is higher in unit A. High smectite and low POC contents in unit B are due to the longer formation period of smectite, almost decomposition of labile organic matter in unit B relative to unit A. High water content in unit B is caused by coarse fabric which results from higher content of spicules and spines. Additionally, stronger electrostatic repulsion force caused by high smectite content also supports high water content in unit B relative to unit A. Variations in heavy metal contents are closely related to the amount of micronodule, which has higher metal contents than that of sediment. Therefore, we conclude that the differences of geochemical characteristics in unit A and unit B are resulted from the different diagenetic durations of unit A and unit B.

Transcriptional regulatory networks underlying the reprogramming of spermatogonial stem cells to multipotent stem cells

정회수,빈진혁,김형준,황대희,이동률,김계성 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-

Spermatogonial stem cells (SSCs) are germline stem cells located along the basement membrane of seminiferous tubules in testes. Recently, SSCs were shown to be reprogrammed into multipotent SSCs (mSSCs). However, both the key factors and biological networks underlying this reprogramming remain elusive. Here, we present transcriptional regulatory networks (TRNs) that control cellular processes related to the SSC-to-mSSC reprogramming. Previously, we established intermediate SSCs (iSSCs) undergoing the transition to mSSCs and generated gene expression profiles of SSCs, iSSCs and mSSCs. By comparing these profiles, we identified 2643 genes that were up-regulated during the reprogramming process and 15 key transcription factors (TFs) that regulate these genes. Using the TF-target relationships, we developed TRNs describing how these TFs regulate three pluripotency-related processes (cell proliferation, stem cell maintenance and epigenetic regulation) during the reprogramming. The TRNs showed that 4 of the 15 TFs (Oct4/Pou5f1, Cux1, Zfp143 and E2f4) regulated cell proliferation during the early stages of reprogramming, whereas 11 TFs (Oct4/Pou5f1, Foxm1, Cux1, Zfp143, Trp53, E2f4, Esrrb, Nfyb, Nanog, Sox2 and Klf4) regulated the three pluripotency-related processes during the late stages of reprogramming. Our TRNs provide a model for the temporally coordinated transcriptional regulation of pluripotency-related processes during the SSC-to-mSSC reprogramming, which can be further tested in detailed functional studies.

한국심해환경연구(KODES) 지역 주상 퇴적물중 금속 및 희토류원소의 지구화학적 특성

정회수,박숭현,김동선,최만식,이경용,Jung, Hoi-Soo,Park, Sung-Hyun,Kim, Dong-Seon,Choi, Man-Sik,Lee, Kyeong-Young 한국해양학회 1997 바다 Vol.2 No.2

심해저 퇴적물중 금속과 희토류 원소의 수직 함량변화 및 변화의 원인을 구명하기 위해 북동태평양 클라리온-클리퍼톤 균열대(Clarion-Clipperton fracture zone) 중남부에 위치한 한국심해환경연구(Korea Deep-sea Environmental Study, KODES) 지역에서 박스코어러(box corer)를 이용해 18개의 주상시료를 채취했다. KODES 지역 퇴적층은 색상변화에 따라 갈색의 Unit I, 연갈색의 Unit II, 흑(갈)색의 Unit III로 분류된다. Unit I은 Unit II에 비해 높은 Ni/Cu비를 가지고, Unit III는 Unit I, II에 비해 현저히 높은 금속함량을 보인다. Unit II는 지화학적 자료에 근거하여 상부의 Unit IIa 층과 하부의 Unit IIb 층으로 세분될 수 있는데, Unit IIb 층은 Unit IIa 층에 비해 높은 구리 및 3+REEs/NASC 비(또는 큰 음의 Ce 이상치) 등의 특징을 보인다. Unit III는 흑갈색의 상부 Unit IIIa 층과 흑색의 하부 Unit IIIb 층으로 세분되는데, Unit IIIb 층은 Unit IIIa 층에 비해 망간, 철 함량이 높다. 연구지역이 속한 태평양 지판의 확장속도와 방향 그리고 약 11-30 Ma 인 Unit III의 연령을 고려할 때 Unit IIIb 층은 동태평양 균열대(East Pacific Rise, EPR) 그리고 적도와 근접한 위치에서 퇴적된 것으로 계산된다. 흑색인 Unit IIIb 층의 높은 망간, 철 함량은 EPR에서 기원한 화산기원의 철, 망간 등을 공급받아 나타난 결과로 보인다. 한편, Unit III는 물론이고 Unit IIb 역시 적도 고생산대의 영향권에 있었고, 따라서 해수중 풍부한 유기체들과 함께 구리, 희토류 원소 등도 Unit IIb, III 층으로 많이 공급되었을 것이다. 퇴적물로 공급된 이들 구리 및 희토류 원소들은 유기물이 분해됨에 따라 스멕타이트 그리고 어류 잔해물(fish bone debris) 등에 잔류한 것으로 보인다. 즉 KODES 지역 주상 퇴적물에서 나타나는 구리 및 희토류 원소의 수직 함량변화는 연구지역이 제3기 말 시기에 적도 고생산대를 지나는 동안 많은 유기물을 공급받아서 초래된 결과로 사료된다. To study the vertical variation of heavy metal and Rare Earth Element (REE) contents in deep-sea sediments, eighteen cores were sampled from the Korea Deep-sea Environmental Study (KODES)-96 area in the C-C zone (Clarion-Clipperton fracture zone), northeast equatorial Pacific. Sediment columns can be divided into three units based on sediment colors and geochemical characters; uppermost Unit I with brown color, middle Unit II with pale brown color and smaller Ni/Cu ratio than the ratio in Unit I, and lowermost Unit III with dark (brown) colors and higher contents of Mn, Ni, Cu, and REEs than those in Unit I and II. Unit II can be divided more into two layers of upper Unit IIa and lower Unit IIb. Unit IIb is characterized by high contents of Cu, 3+REEs (REEs except Ce), smectite, and severely deteriorated fossil tests. Unit III can also be divided into two units; upper Unit IIIa with dark brown color, and lower Unit IIIb with black color and enriched Mn and Fe. The KODES area was located near from the East Pacific Rise (EPR) When Unit III Sediments were deposited, considering the hiatus between Unit II and III (Quaternary-Tertiary boundary) and the spreading rate (10 cm/yr) and direction (north southern west) of the Pacific plate from the EPR. High contents of Mn and Fe in Unit IIIb may be related with hydrothermal influence from the EPR. Meanwhile, Unit IIb (about 2~3 Ma) and Unit III (11~30 Ma) layers were probably formed near (or under) the equatorial high productivity zone, and accordingly received a lot of organic materials. As a result, Cu and 3+REEs, closely associated with organic materials, are enriched in smectite and/or Ca-P composites (fish bone debrise, biogenic apatite) after decomposition and reprecipitation on the sea floor. Higher contents of Cu and 3+REEs in Unit IIb and III are suggested to be the result of abundant supply of organic substances in the equatorial high productivity zone.

KODOS-89 지역 망간단괴의 성인과 분포

정회수,정갑식 한국해양학회 1990 韓國海洋學會誌 Vol.25 No.4

In the KODOS (Korea Deep Ocean Study)-89 area, western part of clarion-Clipperton fracture zones in the northeastern equatorial Pacific, magnate nodules and sediments were sampled during the 'Farnella' cruise in Oct., 1989. Bulk chemical and mineralogical analyses have been made on a suit of ferromanganese nodules and sediments to study the origin and distribution pattern of the nodules. The nodules are classified into three groups based on their origin: diagenetic nodules with high Mn/Fe ratio, Cu, Ni, Zn, Mg, todorokite contents and rough surface texture; hydrogenetic nodules with high Fe, Co, vernadite contents and smooth surface texture; and transitional nodules with intermediate characters between diagenetic and hydrogenetic nodules. Study area is divided into four zones according to the origin and abundance of nodules: far north area where nodules are hydrogenetic and intermediate in abundance; north area where nodules are diagenetic and low in abundance; south area where nodules are diagenetic and intermediate in abundance; seamount area where nodules are hydrogenetic and high in abundance. distribution pattern of manganese nodules in the KODOS-89 area seems to be controlled by latitudinal variation of productivity in water column and sea bottom morphology.

북동중국해 코아 퇴적물의 희토류원소 분포양상과 기원

정회수,임동일,유해수,Jung Hoi-Soo,Lim Dhong-il,Yang Shou Ye,Yoo Hai-Soo 대한자원환경지질학회 2006 자원환경지질 Vol.39 No.1

Rare earth elements(REEs) in transgressive shelf core sediments were analysed to identify constraints of REE distribution patterns and sediment provenances in the northern East China Sea(ECS). Sediments of Chinese and Korean rivers, such as Huanghe and Yangtz rivers, Keum and Yeongsan rivers that supply sediments to the northern ECS, were also analysed to figure out their typical REE distribution patterns. The distribution patterns of Chinese and Korean river sediments, which are normalized with upper continental crust (UCC) REE values, appear to be enriched in middle rare earth elements (MREEs) in Chinese river sediments, whereas in light rare earth elements (LREEs) in Korean river sediments. We assign the MREE-enriched convex-type distribution pattern in Chinese river sediments as 'C-type', and the LREE-enriched linearly decreasing pattern in Korean river sediments as 'D-type'. A major constraint of the REE concentration in northern ECS core sediments is interpreted to be LREE-enriched monazite $((Ce,\;La)PO_4)$ that is ubiquitous in and around the study area. Meanwhile, the distribution pattern of northern ECS sediments appears to be between the C-type and the D-type. We suggest that the nothern ECS sediments are the mixture of China and Korea riverine sediments that have been accumulated in paleo-river mouth, paleo-coast, and present-day shelf environment as well. 북동중국해 코아 퇴적물중 희토류 원소(REE) 함량을 분석하여 REE함량의 분포양상을 파악하고 퇴적물 기원지를 추적하였다. 북동중국해로 퇴적물을 공급하는 한국 강(금강, 영산강 등사 중국 강(황하, 양자강 등)에서 유출된 퇴적물 중 REE함량도 분석되어 한국/중국 강에서 유출되는 퇴적물 중 REE함량의 전형적인 분포양상이 구해졌다. 상부지각 중 REE 함량으로 정규화 된 중국 강과 한국 강 퇴적물 중 REE 함량의 분포양상은 각각 중간 희토류 원소(MREE)와 가벼운 희토류원소(LREE)가 부화된 형태로 나타났다. 중국 강 퇴적물에서 나타나는 REE 함량의 분포양상은 "C-type" 즉 MREE가 부화되어 가운데가 불룩한 형태이고, 한국 강 퇴적물에서 나타나는 REE 함량의 분포양상은 "D-type" 즉 LREE가 부화되어 원자번호가 증가함에 따라 직선적으로 감소하는 형태를 보인다. 북동중국해 코아 퇴적물중 REE 함량의 주요 제한인자는 LREE가 부화되어 있고 연구해역 인근 어디에나 분포하는 모나자이트$((Ce,\;La)PO_4)$로 해석된다. 한편, 북동중국해 퇴적물 중 REE함량의 분포양상은 C-type과 D-type의 중간 형태를 보인다. 이러한 중간 형태에 근거할 때, 현재는 대륙붕 환경이지만 과거에는 강 하구였던 북동중국해의 퇴적물은 한국 강과 중국 강에서 유출된 퇴적물의 혼합체로 판단된다.

자성백서의 난소절제시 악관절 변화에 관한 조직학적 연구

정회수,김경욱,이재훈,김창진,Jung, Hae-Su,Kim, Kyung-Wook,Lee, Jae-Hoon,Kim, Chang-Jin 대한악안면성형재건외과학회 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.2

This investigation studied the effect of ovariectomy on the temporomandibular joint (TMJ) of rat. Forty female Sprauge-Dawley strain white rats, each weighing about 200grams were used and divided into two groups. The one group was performed ovariectomy, and the other was performed sham operation. Both group were killed at the intervals of 3 days, 1, 2, 4, and 8 weeks postoperatively, paraffin section were stained with H&E, MT and histomorphometric study of the TMJ was performed in a synchronous manner with an sham operated control group The result were as follows: 1. At 4 weeks after ovariectomy, an adhesion between the inferior surface of the articular disc and the condyle was observed in the central portion. At 8 weeks after ovariectomy, a focal thickening of the bone (osteophyte) was observed in anterior portion and there was a marked decrease in the trabecular bone in the posterior region. 2. The thickness of cartilage zone was increased at 2 weeks postopratively in the central portion, and decreased at 4 weeks postopratively in the posterior portion. The thickness of transitional zone was decreased at 1 week postoperatively in the anterior and proliferating zone was decreased postoperatively. The thickness of articular zone was decreased at 3 days postopratively in the anterior portion, and decreased at 1 week postoperatively in the central portion. From the above finding, we could conclue that estrogen deficiency in rats causes alteration of TMJ in marked early stage.

Proteomic Analysis of Differently Expressed Proteins in a Mouse Model for Allergic Asthma

정회수,임태연,안미현,윤평오,김성호,정일엽,어수택,김성일,박춘식 대한의학회 2005 Journal of Korean medical science Vol.20 No.4

Allergic asthma is associated with persistent functional and structural changes in the airways and involves many different cell types. Many proteins involved in allergic asthma have been identified individually, but complete protein profiles (proteome) have not yet been reported. Here we have used a differential proteome mapping strategy to identify tissue proteins that are differentially expressed in mice with aller-gic asthma and in normal mice. Mouse lung tissue proteins were separated using two-dimensional gel electrophoresis over a pH range between 4 and 7, digested, and then analyzed by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MS). The proteins were identified using automated MS data acqui-sition. The resulting data were searched against a protein database using an inter-nal Mascot search routine. This approach identified 15 proteins that were differen-tially expressed in the lungs of mice with allergic asthma and normal mice. All 15 proteins were identified by MS, and 9 could be linked to asthma-related symptoms, oxidation, or tissue remodeling. Our data suggest that these proteins may prove useful as surrogate biomarkers for quantitatively monitoring disease state progres-sion or response to therapy.