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폐경기 여성에서 호르몬 대치요법이 골대사의 생화학적 지표에 미치는 영향
정한국,이권해,조태호,이임순,이해혁,이석민 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.3
The purposes of this study were to evaluate the effect of hormone replacement therapy on the bone mineral density and bone metabolism. Thirty-four postmeonpausal women, who visited Soonchunhyang University Hospital were assessed. After baseline study, conjugated equine estrogen [CEE, 0.625 mg, day 1∼30] plus medroxyprogesterone acetate [MPA, 5 mg, day 1∼12] were given for 12 months. The levels of serum osteocalcin, serum total alkaline phosphatase and urine deoxypyridinoline decreased significantly[p<0.05] after 12 months of hormone replacement therapy. Bone mineral density of Ward`s triangle of femur increased significantly[p<0.05] compared to basal level and 12months of hormone replacement therapy. These data suggest that hormone replacement therapy has effect of inhibiting bone turnover rate and increasing bone mineral density of Ward`s triangle of femur in postmenopausal women.
정상근,권준수,2006 한국인의 불안 리서치 그룹,Chung, Sang-Keun,Kwon, Jun-Soo 대한불안의학회 2006 대한불안의학회지 Vol.2 No.2
Objectives : We performed this '2006 Korean Anxiety Research' to understand the actual state about Korean anxiety and get the basic data for mental health promotion. Methods : Semistructured questionnaire and Beck Anxiety Inventory -Korean version (BAI) were administered to total 1,000 adults (20-69 years old 501 male & 499 female adults living in Seoul and 5 metropolitan cities in Korea) on March 20th~31st, 2006. Results : Anxious subjects by the total score of BAI was 3.3%. But the responders the item 'I am in the anxious state' was 25% among total subjects. 6% (n=59) among total subjects were the responders experienced the anxiety requiring usually the counselling or treatment. The frequency of their anxiety was most commonly 1 to 2 times/month. The main causes of their anxiety were 'their health problems or illness', 'economic difficulty', 'interpersonal conflicts'. But 'help by health professional' among their usual anxiety reduction methods' was only 15% among them. Only 19% among them were under the treatment of anxiety. Only 27% among 48 subjects not under the treatment of anxiety had a desire for the anxiety treatment in the near future. Conclusion : Some people in the anxious state impairing their daily lives were not yet under the treatment. And most of them had no desire for the anxiety treatment. Therefore we will systematically plan the further health education on the anxiety-related problems for the Korean mental health promotion and the quality of life.
Statistical analysis and genetic diversity of three dog breeds using simple sequence repeats
정호임,김희수,최봉환,어정우,권윤정,이희은,최유리,김정안,김태훈,성환후,이동훈,하지홍,한국일 한국유전학회 2014 Genes & Genomics Vol.36 No.6
There are more than 400 pure dog breedsdeveloped through intentional artificial selection andpurebred breeding. Purebred animals have higher risk ofinbreeding depression and hereditary diseases. We investigatedthe genetic diversity and structure of three dogbreeds in South Korea by using 12 microsatellite loci forone Korean native dog breed, Sapsaree, and two foreignbreeds, German shepherd and Belgian Malinois. The meanallele number of nine loci across all dog breeds was 4.833,and the number of alleles per locus ranged from 2 to 8. Themean of expected and observed heterozygosity were 0.415and 0.577, respectively. Sapsaree, Korean native dog, hadhigher level of genetic diversity than the foreign Germanshepherd and Belgian Malinois. The highest mean value ofpolymorphism information content was found in Sapsaree(0.480), followed by Belgian Malinois (0.373) and Germanshepherd (0.355). Pairwise genetic differentiation wasestimated using fixation index FST. Sapsaree and Germanshepherd (FST = 0.2536) and Sapsaree and Belgian Malinois(FST = 0.2522) had very great genetic differentiation,while moderate level of genetic differentiation wasobserved between German shepherd and Belgian Malinois(FST = 0.1003). These genetic information and structure ofthe three dog breeds will be effective in conservation andpreservation of the genetic diversity of the three dogbreeds.
집단미술치료가 학교부적응 청소년의 학교적응과 우울 및 자아존중감에 미치는 효과
한국화,정여주 한국심리치료학회 2009 한국심리치료학회지 Vol.1 No.2
본 연구는 집단미술치료가 학교부적응 청소년의 학교적응과 우울 및 자아존중감에 미치는 효과를 검증하기 위한 것이다. 연구대상은 충청도 소재 A중학교 1학년 14명이며, 실험집단 7명과 통제집단 7명으로 나누어 치료집단의 효과를 검증하였다. 집단미술치료는 매주 90분씩 2회기로 총 12회기를 실시하였고, 연구에 사용한 측정도구는 다음과 같다. 학교부적응을 측정하기 위해 김용래(2000)가 제작한 학교적응척도를 사용하였고, 우울의 측정도구로는 BDI를 자아존중감의 측정도구로는 Coopersmith(1981)가 제작한 자아존중감 검사를 장은진(2004)이 수정․보완한 것을 사용하였다. 이러한 도구를 이용하여 얻은 점수는 SPSS WIN 12.0 프로그램의 t-검증을 이용하여 분석하였으며, 그 결과 각 변수마다 유의수준은 달랐지만 집단미술치료가 학교부적응 청소년의 학교부적응과 우울을 낮추고 자아존중감을 높이는데 긍정적인 영향을 미칠 수 있음을 검증할 수 있었다. 이러한 집단미술치료프로그램은 미술이 지닌 치유적 특성을 통해 청소년들의 정서적 건강과 학교적응에 도움이 되었으며, 나아가 미술매체를 통한 치유의 가능성과 필요성을 재인식하는 계기를 마련하였다는 점에서 의의가 있다. 주요어 : 집단미술치료, 학교부적응, 우울, 자아존중감