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아파트 외부공간의 감성적 요소가 주거소비행태에 미치는 영향에 관한 연구
정은혜,정준현,Jung, Eun-Hye,Jeong, Jun-Hyun 한국주거학회 2011 한국주거학회 논문집 Vol.22 No.3
The purpose of the research is analyzing how the emotional factors of the external apartment design can be influenced by the consumers' emotional reaction, and analyzing how the emotional reaction of the consumers will affect the expenditure of the apartment in the upcoming future. For this purpose, first, external surrounding factors of the apartment are extracted and then classified into three major design categories (instinctive, behavioral, and reflective design), and each factor is evaluated by the emotional evaluation. The scope of the research is restricted to the apartments in Daegu city which are built by Top 3 construction companies from the analysis of construction-working rank (May, 2010). The residential-expenditure data are extracted from D-univ. students, in accordance with the satisfaction of the external surroundings and emotional-reaction against the emotional-design factors of the apartment. This research is done by the statistic analysis program SPSS17.0. This shows that difference of emotional design by the apartment external space requisites will be significance as fundamental data for development of application and planning and apartment external space of emotional design by the apartment external space in the future.
Human Norovirus Replication in Temperature-Optimized MDCK Cells by Forkhead Box O1 Inhibition
정은혜,조세영,Bipin Vaidya,하상훈,전상미,노현주,이유정,이주혜,권요셉,김두운 한국미생물·생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.9
Human noroviruses (HuNoVs) are a leading cause of gastroenteritis outbreaks worldwide. However, the paucity of appropriate cell culture models for HuNoV replication has prevented developing effective anti-HuNoV therapies. In this study, first, the replication of the virus at various temperatures in different cells was compared, which showed that lowering the culture temperature from 37°C significantly increased virus replication in Madin-Darby canine kidney (MDCK) cells. Second, the expression levels of autophagy-, immune-, and apoptosis-related genes at 30°C and 37°C were compared to explore factors affecting HuNoV replication. HuNoV cultured at 37°C showed significantly increased autophagy-related genes (ATG5 and ATG7) and immune-related genes (IFNA, IFNB, ISG15, and NFKB) compared to mock. However, the virus cultured at 30°C showed significantly decreased expression of autophagy-related genes (ATG5 and ATG7), but not significantly different major immune-related genes (IFNA, ISG15, and NFKB) compared to mock. Importantly, expression of the transcription factor FOXO1, which controls autophagy- and immune-related gene expression, was significantly lower at 30°C. Moreover, FOXO1 inhibition in temperature-optimized MDCK cells enhanced HuNoV replication, highlighting FOXO1 inhibition as an approach for successful virus replication. In the temperature-optimized cells, various HuNoV genotypes were successfully replicated, with GI.8 showing the highest replication levels followed by GII.1, GII.3, and GII.4. Furthermore, ultrastructural analysis of the infected cells revealed functional HuNoV replication at low temperature, with increased cellular apoptosis and decreased autophagic vacuoles. In conclusion, temperature-optimized MDCK cells can be used as a convenient culture model for HuNoV replication by inhibiting FOXO1 and providing adaptability to different genotypes.
정은혜,정경원 忠南大學校體育科學硏究所 2002 體育科學硏究誌 Vol.20 No.1
The purpose of this study was to survey the preschool institution educators in Seoul and Daejeon, on order to document their perceptions with regard to the dance education. 400 subjects were randomly selected and 110 subjects from 49 institutions in seoul and 136 subjects from 63 institutions in Daejeon completed questionnaires. The modified questionnaire used based on the previous studies Won(1987), Park(1999) and Yi(2001). Descriptive and x^2 were used to analyze the data collected. The results of this study were following as: 1) Most of preschool institution teachers considered the concept of preschool dance instruction as creative expression activities to motivate preschool infants. 2) Dance program was provided for infants for 10 minutes to 20 minutes once a week or twice a week. Every infant actively participated in dance program. Female infants showed more interesting in the program than male ones. 3) Dance program considered of Ballet, rhythmical movement, Korean traditional dance, and folk dance. 4) Most of teacher utilized workship or terminal seminar and the cassette tape in a effort to acquire a series of dance instructional goals. Meanwhile Most of infants used to put on slippers with rubber-coated outsold, when they performed the activities of dance instruction even as sportswear of casuals. 5) Teachers motivated infants to express actively their own emotion or feeling. They found it necessary to train professional instructors in dance.
정은혜 한국방언학회 2016 방언학 Vol.0 No.24
This paper aims to study the phonetic realization of /h/ after obstruent stop in Korean dialects, and to predict how the trends and patterns will change. The study reviews previous studies and consults motivational aspects of aspiration and /h/ eliminated pattern. These information are categorized by dialects to see how the patterns actually appear in each of dialects. Furthermore, the study looks into the younger generation’s use of /h/ after obstruent stop. The results demonstrate aspiration pattern in central dialect, /h/ eliminated pattern in southwestern dialect, and both patterns in southeastern dialect. Northwestern and northeastern dialects could have used stop-/h/ chain pattern in the past, however, now it is more likely that the pattern have progressed toward aspiration. Regarding dialect speakers in their twenties or thirties, their application of aspiration have widened over time in all dialects and this trend is projected to sustain in the future. 이 논문은 파열음 후행 ‘ㅎ’의 연쇄가 방언별로 음성적으로 어떻게 실현되는지를 살펴보고, 앞으로의 변화 양상을 예측해 보는 것을 목적으로 한다. 이를위해 선행 연구 및 방언화자의 직관을 토대로 격음화 유형과 ‘ㅎ’탈락 유형의등장 과정 및 음성적인 동기를 살펴보고 방언별로 실현 양상을 정리하여 보았다. 또한 젊은 세대들의 출신 지역별로 파열음 후행 ‘ㅎ’의 실현 양상을 조사하여 그 추이를 살펴보았다. 그 결과 중앙어에서 격음화 유형이 발생하였고 서남부 지역에서 자생적으로‘ㅎ’탈락 유형이 발생하였으며, 동남방언에서는 ‘ㅎ’탈락 및 격음화 유형이 동시에 일어난 것으로 판단하였다. 서북, 동북방언은 ‘파열음-ㅎ’ 연쇄 발음을 하였을 수 있으나 현재에는 광범위하게 격음화가 진행되었을 가능성이 크다고 판단하였다. 20~30대 화자들에 대한 조사 결과 모든 방언권에서 격음화의 적용 범위가 넓어졌으며 앞으로의 변화도 ‘격음화’의 방향으로 진행되는 것이 더 쉬울것으로 여겨진다.