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        • 조영제가 가토 난관에 미치는 영향에 대한 실험적 연구

          정은철 梨花女子大學校 醫科大學 醫科學硏究所 1992 EMJ (Ewha medical journal) Vol.15 No.3

          Hysterosalpingography is a valuable diagnostic tool in the investigation of the uterine and tubal factors of female infertility. Author evaluated the effect of different iodinated contrast agents on the fallopian tube and adnexal tissue in 16 rabbits. Lipiodol, an oil-soluble agent, was used for 4 rabbits. The following water soluble contrast agents were used for 12 rabbits: iothalamate meglumine 60%, diatrizoate sodium, and iopromide. The agents injected through the catheter placed in the fallopian tube. Fallopian tubes and peritoneal cavities were evaluated histologically. Iothalamate meglumine and diatrizoate sodium contrast agents, were associated with mild to moderate Inflammation and edema. Iopromide. which has low osmolarity, produced mild inflammation compared to ionic contrast agents. Use of oil-soluble contrast medium resulted in fibrous adhesion, moderate to marked inflammation and tissue edema in fallopian tubes andperiovarian tissues. The safety of oil-soluble contrast agents for hysterosalpingogrpahy is questioned. Therefore, contrast agents with low osmolarity are suitable for use in hysterosalpingography.

        • 요추간판탈출증의 자기공명영상소견

          정은철,서정수 梨花女子大學校 醫科大學 醫科學硏究所 1992 EMJ (Ewha medical journal) Vol.15 No.4

          Magnetic resonance imaging(MRI) of 47 patients with surgically confirmed lumbar disk herniation at 62 levels was studied retrospectively to evaluate the significance of MRI in diagnosis of lumbar disk herniation. Prolapsed type of lumbar disk herniation is 47 cases(76% ). lumbar disk herniation at L4-L5 level is 33 cases(53 %) and posterolateral herniation is 54 cases(87%). 6 cases(10%) of lumbar disk herniation in MRI were not matched with operative findings, due to lumbar scoliosis(4 cases) and lumbarization of S1 (2 cases). Associated abnormalities are 4 cases of Schmorl's nodule and 2 cases of spondylolisthesis, MRI shows excellent sagittal image and can differentiate extruding type of lumbar disk herniation from prolapsed type. The result of the study indicates the MRI is likely to become the initial procedure of choice for evaluating patients with suspected lumbar disk herniation. If clinically incompatible with MRI findings, it is desirable that CT and/or myelography are complementary to MRI study.

        • KCI등재

          Tuberous Sclerosis의 전산화단층촬영 소견

          정은철 대한영상의학회 1988 대한영상의학회지 Vol.24 No.6

          Computed tomgraphy has been established as a useful imaging method in the diagnosis of tuberous sclerosis. By demonstrating the characteristic intracranial lesion it allows confirmation of the diagnosis and provides a noninvasive means of evaluating the patient with seizure and mental retardation. Authors analysed CT findings in 20 cases of tuberous sclerosis since March 1985 through August 1988. the results were as follows: 1) There are 14 men and 6 women with the age ragng from 6 months to 45 years. 2) Ventricular calcified tubers are noted at the frontal horn (16/20 80%) body (13/20, 65%) atrium (9/20, 45%) of the lateral ventricles 1 cases shows the hamartoma near the foramen of Monro. 3)In the cortical region 1 case of high density tuber and 2 cases of focal atrophy are noted. 4) In the white mater 3 cases of amorphous calcifications and 1 cases of demyelinating hypodensity are seen,

        • KCI등재

          Digital Radiography를 이용한 원발성 폐섬유화증의 검출능에 대한 ROC 연구

          정은철 대한영상의학회 1991 대한영상의학회지 Vol.27 No.2

          One potential advantage of the digital radiography system is its ability to enhance image quality by various types of processing. Digital unsharp masking is one of the simplest and most useful forms of enhancing processes. The efficacy of unsharp masking in radiological diagnosis has not been investigated thoroughly. To evaluate the effects of unsharp masking in film-digital chest images, 3 observers were shown 150 test radiographs. These test radiographs consisted of 50 unprocessed images(25 normals and 25 patients with idiopathic pulmonary fibrosis with honey combing) adn their 100 processed images by using 450 and 15-sized masks respectively. An ROC analysis of these data suggests that unsharp masking is more effective in detecting idiopathic pulmonary fibrosis than unprocessed image(P<0.05), and so it may improve diagnostic accurary for interstitial fibrosis. In addition, the smaller mask size(15) is more effective than the larger one(mask size 45)(p<0.05). By using this analytic approach, an optimal parameter in digital chest radiography may be investigated in many other forms of pulmonary disease such as pulmonary nodule or mediastinal mass.

        • KCI등재
        • KCI등재
        • KCI등재

          복합수지운동에서 소뇌의 양측성 기여에 관한 기능적 자기공명영상 연구

          정은철 대한영상의학회 1999 대한영상의학회지 Vol.40 No.1

          Purpose : To demonstrate activation signals within the cerebellar cortex and to determine the side of the cerebellar cortex eliciting activation signals in response to complex motor tasks, as seen on EPI fMRI Materials and Methods : Seven right-handed subjects (M : F = 3 : 4 ; mean age, 30.3 years) underwent repetitive finger apposition with the dominant right hand. Using a 1.5 T MRI scanner, EPI fMR images were obtained. MR parameters used for EPI fMRI were TR/TE/Flip angle : 0.96 msec/64 msec/90$^{\circ}$, FOV 22cm, 128 $\times$ 128 matrix, 10 slices, 10 mm thickness while those for SE T1 weighted localized images were TR/TE : 450/16, FOV 23cm, 256 $\times$ 256 matrix. The paradigm was three sets of alternate resting and moving fingers for six cycles, resulting in times of 360 seconds (10 slices $\times$ 15 EPI $\times$ 6 cycles = 900 images). Image processing involoved the use of a 200mHz Dual Pentium PC with homemade software. T-testing (p < 0.005 ~ p < 0.0005) and time series analysis were performed, and to verify the locations of activated regions, resulting images were analyzed in a color-coded overlay to reference T1-weighted spin echo coronal images. percentage change in signal intensity (PCSI) was calculated from the processed data. Results : All normal subjects showed significant activation signals in both the contralateral (left) primary motor cortex (PCSI = 3.12% $\pm$ 0.96) and ipsilateral (right) cerebellar cortex (PCSI = 3.09%$\pm$ 1.14). Signal activation was detected in the contralateral supplemental motor area (2.91% $\pm$ 0.82), and motor activation in the anterior upper half of the contralateral cerebellum (PCSI = 2.50% $\pm$ 0.69). The difference in activation signals between both sides of the cerebellar cortex was not statistically significant. All data were matched with time-series analysis. Conclusion : Bilateral cerebellar activation is associated with unilateral complex finger movements, as seen on fMRI. This result maysupport the recent neurological observation that the cerebellum may exert bilateral effects on motor performance.

        • KCI등재

          ROC방법을 이용한 방사선학적 소견의 관찰능력의 분석

          정은철 대한영상의학회 1988 대한영상의학회지 Vol.24 No.6

          Analysis in terms of the receiver operating characteristic curve (ROC) has recentely been applied to evaluate medical imaging technique. This paper presents a brief description of ROC and shows how it provides a measure of diagnostic observer performance. Test radiographs of 5 by 5 cm film were shown to 4 observers. Radiographs containing 2 mm lucite bead plus noise or noise only were obtained with 3 film-screen combinations as AOG+KS, AOG+KH and AO+KH, Individual ROC curves of 4 observers and 3 film-screen combinations and pooled ROC curves were analysed. No definite difference of oserver performance between 4 observer and there was superior ROC curve in AO+KH combination than others. The results demonstrate that ROC analysis was useful for evaluating observer performance in detecting task of diagnostic imaging technique.

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