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      • KCI등재

        가족성 가성고칼륨혈증의 헌혈 혈액 및 수혈 결과에 대한 영향

        정유선,김한주,김형석,고대현 대한수혈학회 2023 大韓輸血學會誌 Vol.34 No.2

        Familial pseudohyperkalemia (FP) is a dominantly inherited condition caused by variants in the gene ABCB6 resulting in red blood cell (RBC) membrane protein defects. FP is generally asymptomatic. However, FP RBCs have an increased permeability to monovalent cations when stored below 37°C. Transfusion of RBC components donated by FP individuals can induce hyperkalemia and may be causally related to transfusion-associated hyperkalemic cardiac arrest, particularly in neonates and infants. Therefore it is necessary to accurately evaluate the frequency of FP occurrence in the Korean population and assess whether FP RBCs have significantly higher supernatant potassium levels. Efforts should be made to recognize the effects of blood products collected from FP donors on blood transfusion recipients to reduce the risk of hyperkalemia, especially in fetuses, infants, and patients at risk of this condition.

      • KCI등재

        Formyl peptide receptors in the mucosal immune system

        정유선,배외식 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-

        Formyl peptide receptors (FPRs) belong to the G protein-coupled receptor (GPCR) family and are well known as chemotactic receptors and pattern recognition receptors (PRRs) that recognize bacterial and mitochondria-derived formylated peptides. FPRs are also known to detect a wide range of ligands, including host-derived peptides and lipids. FPRs are highly expressed not only in phagocytes such as neutrophils, monocytes, and macrophages but also in nonhematopoietic cells such as epithelial cells and endothelial cells. Mucosal surfaces, including the gastrointestinal tract, the respiratory tract, the oral cavity, the eye, and the reproductive tract, separate the external environment from the host system. In mucosal surfaces, the interaction between the microbiota and host cells needs to be strictly regulated to maintain homeostasis. By sharing the same FPRs, immune cells and epithelial cells may coordinate pathophysiological responses to various stimuli, including microbial molecules derived from the normal flora. Accumulating evidence shows that FPRs play important roles in maintaining mucosal homeostasis. In this review, we summarize the roles of FPRs at mucosal surfaces.

      • KCI등재

        일부 보건계열 대학생들의 구강건강 예방관리와 구강건강신념의 관련성

        정유선 한국치위생감염관리학회 2024 한국임상치위생학회지 Vol.12 No.1

        Objectives: This study examined the relationship between oral health belief and oral health preventive management among health college students. The study also determined if oral disease recognition is related to oral health preventive management. Methods: A survey was of 385 health-related college students in Chungcheongnam-do was conducted to determine the relationship between oral health preventive management and oral health belief. t-teat, ANOVA, correlation and regression analysis were conducted. Results: Differences in oral health belief and the use of oral supplementary hygiene products were noted as 2.14 for “using” oral supplementary hygiene products and 2.43 for “not using” (p<0.01). The effect of oral health belief on oral hygiene product awareness was in the order of disability, importance, and benefit (p<0.01). Conclusions: To prevent oral diseases and manage oral health, regular oral examinations to assess for oral diseases and to provide continuous oral education, raise awareness of various oral hygiene products, increase the importance and benefits of oral health preventive management, and reduce disability through continuous feedback.

      • KCI등재

        청말 儒醫 曾懿의 젠더의학과 ‘여성’ 재구성 - 古歡室醫書 三種을 중심으로 -

        정유선 동아시아고대학회 2022 동아시아고대학 Vol.- No.68

        曾懿(1852-1927)는 청나라 말에서 민국 초기에 활동했던 여성 儒醫으로, 사대부 가문에서 태어나 경전과 사서를 익혔으며 시서화에 뛰어났다. 그는 어려서부터 몸이 약해 늘 질병에 시달렸고 전염병도 여러 차례 겪으며 자연스럽게 의술에 관심을 가지게 되었다. 결국 본인이 직접 독학으로 고대부터 당시까지의 의학 전적들을 두루 탐독하고 민간요법들도 익혀 자신의 병 치료는 물론 주위 사람들에게도 의술을 베풀었다. 그녀는 이러한 연구와 임상경험을 바탕으로 흔히 ‘古歡室醫書 三種’이라고 불리는 『醫學篇』, 『女學篇』, 『中饋錄』을 차례로 저술하고 출판했다. 증의가 태어나 활동하던 청말민초는 청나라가 아편전쟁 패배 이후 외세 열강의 침입으로 급속히 쇠락 국면에 들어서면서 중국 전역에서 망국으로 치닫는 조국 청나라를 다시 일으키기 위한 거센 움직임이 있을 시기였다. 이러한 사회 움직임은 세계열강이 된 배경의 핵심이 ‘근대화’임을 파악하고 계몽과 개혁을 통해 근대화된 부국강병한 국가를 만들기 위함이다. 이에 여성 유의 증의가 파악했던 근대를 상징하는 언표는 바로 ‘여성’과 ‘의학(의술)’이었다. 이는 증의에게 있어 단순히 여성의 몸을 치료하는 성별 의술만이 아니었다. 이는 여성 성별 의술과 여성 젠더적 의학 담론을 바탕으로 청을 망국의 길로 접어들게 했던 원인 중 하나인 기존 전통적인 여성에 대한 인식과 역할에서 탈피해 청의 부국강병에 일조하는 여성으로 개조하기 위한 실천적 방안의 제시였다. 바로 증의는 기존의 여성 의학 영역을 질병이나 상해의 치료에서 보건과 예방까지 확장하고 여성의 사적 영역과 공적 영역을 모두 포함한 근대 여성으로서 지향해야 할 지표를 제시하고자 했다. 증의의 이 두 언표는 사회 참여와 소통의 메시지였던 것이다. 이에 본 고에서는 전통적인 사회환경에서 교육을 받은 증의가 여성 유의로서 서구 근대 여성 교육에서 출발한 여성 주체 의식이 아닌 증의 개인 자체적으로 자각하고 생성한 여성 주체 의식과 실천적 사회 참여 활동에 초점을 맞춰 연구를 진행했다. 증의의 고환실의서 3종을 통해 기존의 여성을 배제한 여성운동과 담론 혹은 구체적인 실천적 제시가 미흡하다고 지적받는 여성운동과는 다른 청말 실천적 여성운동 양상을 고찰했다. Zeng-Yi(1852-1927) was a female monk who was active in the late Qing Dynasty and early Republic; she was born into a noble family, learned scriptures and librarians, and excelled in poetry and calligraphy. She suffered from diseases from a young age due to her weak body, and her ailments and the infectious diseases that afflicted her induced a natural curiosity in medicine. Ultimately, she taught herself to read medical records ranging from ancient to contemporary, learned folk remedies, and administered medication to people around her to treat illnesses. Based on these studies and clinical experience, she wrote and published “three kinds of Guhuanshi medical books,” consecutively. Zeng-Yi was born and active during a time when there was a strong movement to revive the Qing Dynasty, which was heading toward ruin throughout China owing to it entering a rapid decline due to the invasion of foreign powers after the Opium War. This social movement is to understand that the core of the background of becoming a world power is ‘modernization’ and to create a modernized rich and strong nation through enlightenment and reform. Accordingly, the signs that symbolize the modern times identified by women's significance were ‘women’ and ‘medical(medication)’. This was not just gendered medicine to treat women's bodies, but a practical way for a woman who contributes to the wealth and strength of Qing Dynasty to transform it, breaking away from the stereotypical perception and role of women, which is one of the reasons for entering the country based on female gender medicine and medical discourse. The intention was to expand the existing field of women's medicine from the treatment of disease or injury to health and prevention, and to provide indicators for modern women, in women's private and public areas. These two signs of evidence were messages of social participation and communication. Therefore, this study focused on women's self-awareness and practical social participation activities of women's self-awareness, not women's self-awareness stemming from Western modern women's education. Through the three types of evidence, we examined the aspects of the women's movement, which are different from the women's movement that excludes existing women, and the women's movement, which is pointed out as lacking concrete practical presentation.

      • KCI등재

        중국의 경영환경 변화와 외국상회의 역할

        정유선,정선욱 한양대학교 아태지역연구센터 2013 중소연구 Vol.37 No.1

        This paper seeks to discuss an increasingly important role of foreign business associations in China under the recent changes in business environment. Foreign companies in China are facing greater challenges than before, since overall business environment, which is characterized by increased competition, a series of new rules and regulations, and selective favor by local stakeholders, constrains their business. Against this backdrop, as entities representing collective interests of member companies,foreign business associations have put spurs on various activities, while interacting with local government and local community. Empirically,detailed description on the current state and activities of three foreign business associations in Shanghai (American, Korean, and Taiwanese chambers of commerce) is offered. Foreign business associations in China have emerged as important actors interacting with the transitional institutional environment, and this study aims to lay the groundwork for further studies on this issue. 이 글은 경영환경의 변화 속에 그 중요성이 더욱 커진 중국내 외국상회의 현황및 활동을 논의한다. 중국경제발전에 큰 역할을 수행한 외국인직접투자 (FDI)는2000년 이후 큰 변화를 맞게 되었다. WTO가입으로 중국내 기업간 경쟁이 더욱치열해졌고, 유관 법률 및 집행 강화, 외자기업에 대한 우대혜택 축소 등으로 외자기업들은 직간접적으로 여러 어려움을 직면하게 되었다. 이런 배경하에서 외자기업의 이익과 목소리를 대변하는 단체로서 외국상회의 역할이 더욱 중요해졌고 각국의 상회는 다양한 활동을 통해 중국 정부 및 지역사회와 상호작용하고 있다. 이글은 현실적인 중요성에도 불구하고 아직 연구가 미진한 중국내 외국상회에 대해두 저자의 현지조사를 통해 얻은 자료를 바탕으로 상하이 지역의 미국, 한국, 대만상회의 현황 및 활동을 소개한다. 큰 틀에서 본 연구는 외국상회가 어떠한 방식으로 변화하는 제도 환경에 대응하고 상호작용을 주고받는가를 살펴보기 위한 기초작업이며, 이를 통해 중국내 외국상회에 대한 본격적인 후속 연구를 위한 토대를제공하고자 한다.

      • KCI등재후보

        예술중심 융합교육에서 모바일 증강현실(AR)의 활용방안

        정유선 동국대학교 영상문화콘텐츠연구원 2016 영상문화콘텐츠연구 Vol.0 No.-

        본 연구는 예술중심 융합교육에서 모바일 증강현실(AR)의 활용방안을 모색하는데 목적이 있다. 연구의 목적을 달성하기 위해 문헌연구를 바탕으로 예술중심 융합교육과 모바일에서 증강현실의 활용방안을 설정하였다. 초등학생을 대상으로 한 예술중심 융합교육에서 사물놀이를 중심으로 소리와 색을 연계하여 공감각적 체험과 또래 집단에서 협업의 기회를 제공할 수 있는 방안을 제안하였다. 본 연구의 결론은 첫째, 예술중심 융합교육에서 소리와 색의 요소를 자연스럽게 공감각적 융합 활동으로 체험할 수 있도록 하였다. 둘째, 모바일 증강현실 적용 과정에서 또래 집단을 통한 협업의 기회를 제공할 수 있다. 셋째, 변화하는 스마트러닝 환경에서 모바일 기기를 이용해 전통문화의 이해교육이 이루어질 수 있도록 하였다. The purpose of this study is to develop a plan for applying mobile augmented reality (AR) to art-based convergence education. For this purpose, a plan for applying mobile AR to art-based convergence education was developed on the basis of literature review. A plan for associating sounds with colors through samullori in art-based convergence education for elementary school children was suggested to give opportunities to have synesthetic experiences and cooperate in peer groups. The following conclusion was drawn: First, children were allowed to deal with the elements of sounds and colors naturally through synesthetic convergence activities in art-based convergence education. Second, it is possible to give opportunities to cooperate in peer groups during the course of mobile AR application. Third, mobile devices can be used to give education for understanding traditional culture in a changing smart learning environment.

      • KCI등재
      • KCI등재

        Fabrication of Nearly Monodispersed Silica Nanoparticles by Using Poly(1-vinyl-2-pyrrolidinone) and Their Application to the Preparation of Nanocomposites

        정유선,전미영,김창근 한국고분자학회 2009 Macromolecular Research Vol.17 No.1

        To fabricate dental nanocomposites containing finely dispersed silica nanoparticles, nearly monodispersed silica nanoparticles smaller than 25 nm were synthesized without forming any aggregates via a modified solgel process. Since silica nanoparticles synthesized by the Stober method formed aggregates when the particle size is smaller than 25 nm, the synthetic method was modified by changing the reaction temperature and adding poly(1- vinyl-2-pyrrolidinone) (PVP) to the reaction mixture. The size of the formed silica nanoparticles was reduced by increasing the reaction temperature or adding PVP. Furthermore, the formation of aggregates with primary silica nanoparticles smaller than 25 nm was prevented by increasing the amount of PVP added to the reaction mixture. To enhance the dispersion of the silica particles in an organic matrix, the synthesized silica nanoparticles were treated with 3-methacryloxypropyltrimethoxysilane (γ-MPS). A dental nanocomposite containing finely dispersed silica nanoparticles could be produced by using the surface-treated silica nanoparticles.

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