저해음 -t-l 연속에서의 /t/의 생략

정유리 한국영어학학회 2001 영어학연구 Vol.- No.11

Prognostic Factors for Distant Metastasis in Patients with Loco-regional Recurrence after Mastectomy

정유리,김수산,공경엽,이희진,안세현,손병호,이종원,최은경,이상욱,안승도 한국유방암학회 2015 Journal of breast cancer Vol.18 No.3

Purpose: The purpose of this study was to identify patients with high risk of distant metastasis (DM) after salvage treatment for postmastectomy locoregional recurrence (LRR). Methods: We retrospectively reviewed 142 patients who received salvage radiotherapy with or without wide excision for isolated LRR after mastectomy between January 1999 and December 2012. Distant metastasis-free survival (DMFS) was estimated from the date of diagnosis of isolated LRR to the date of DM or last follow-up using the Kaplan-Meier method, and Cox regression analysis was performed to identify prognostic factors for DM. Results: The median follow-up period was 54 months. The major failure pattern was DM (56%) and the 5-year DMFS was 43%. In multivariate analysis, initial N (iN) stage, recurrent N (rN) stage, and hormone receptor (HR) status were significant prognostic factors for DM (5-year DMFS: iN0 vs. iN1-3, 73% vs. 25%, p<0.001; rN0 vs. rN1-3, 61% vs. 29%, p<0.001; HR+ vs. HR–, 49% vs. 21%, p<0.001). Conclusion: Patients with lymph node involvement and/or HR– specimens seem to experience more DM than patients with chest wall-only recurrence and HR+ specimens. Further studies are needed to investigate the role of chemotherapy in these patients.

컨테이너 활용 복합문화공간 사례연구를 통한 공간특성

정유리,어성신,황연숙 한국실내디자인학회 2019 한국실내디자인학회논문집 Vol.28 No.6

Multi-functional complex cultural spaces have emerged to satisfy the needs of people as the quality of people’s lives has been improved owing to rapid social development. Moreover, architecture using containers has been established as a way to accommodate the rapidly changing culture. Therefore, this study aimed to present measures for activating container complex cultural spaces by analyzing the characteristics of them. This study evaluated 7 container buildings constructed in Seoul since 2015 to draw the following results. The characteristics were classified into modularity, convenience, symbolism, connectivity, variability, and environment-friendliness. Analyzing the characteristics of seven container complex cultural spaces, the results showed that modularity > convenience > symbolism > connectivity > variability and eco-friendly in the chronological order. Modularity was the highest, and variability and environment-friendliness. were the lowest. Analysis of the module characteristic of the container shows that it was designed with a container module space of a certain size, using the regular size of the container. In particular, when expanded through incisions, large spaces were planned by utilizing and attaching the horizontal modules of the containers. Analysis of the symbolic characteristic of the container shows that the internal and external finishes of the container were used in a different way, and were not reminiscent of the container’s unique characteristics. Analysis of the environment-friendliness characteristic of the container shows that heating and cooling equipment were installed to improve insulation and ventilation of containers, but equipment to save energy was not installed. Various energy saving methods such as solar and geothermal power should be introduced.

뮤지엄에서 관람객들의 여정을 통한 참여적 전시

정유리,반영환 한국디자인문화학회 2019 한국디자인문화학회지 Vol.25 No.1

More and more modern people are visiting the museum for cultural life, and the museum is changing to an exhibition where visitors can participate directly in the exhibition. A simple survey was conducted to understand the perception of participatory exhibitions and studied them through literature survey and direct visit to the exhibition hall. The study aims to differentiate the methods of participation in exhibitions as visitors’ journeys and to analyze the state of participatory exhibitions by setting examples as the basis. Through the questionnaire survey, we know that visitors were more likely to prefer the participatory exhibition to the viewing(only see) exhibition because it increased the understanding of the exhibit and remained in memory. visitors were more inclined to visit the museum if they directly participated in the work of the artist. Before and during the exhibition in the museum, and after the exhibition, we analyze how the visitors participate in the exhibition according to the example. Visitors may participate in the production of the work before the exhibition is held in the museum. During the exhibition, you will learn what kind of attempts are being made to encourage visitors to participate in the museum and examine the participation method of visitors through workshops in the museum. With the influx of capital, the museum provides visitors with new experiences that we have not been able to do. visitors can participate in exhibitions as interactive works as possible through the development of technology. Finally, you can participate as part of the exhibition by sharing or reviewing the comments and information you felt after the exhibition. Based on this paper, we will plan and display exhibitions for visitors to participate in the exhibition. 문화생활을 위해 점점 많은 현대인들이 뮤지엄에 방문하고 있고, 뮤지엄은 보기만하는 전시에서 관람객들이 직접 참여할 수 있는 전시로 변화하고 있다. 참여적전시에 대한 인식을 알기 위해 간단한 설문조사를 하였고, 문헌조사 그리고 직접 전시장에 방문을 통해서 연구하였다. 본 연구는 관람객의 여정으로 전시에 참여방법을 구분하고, 근거로 예시를 두어 참여적 전시의현황을 분석하는데 목적을 두었다. 관람객들은 관람형(보기만 하는) 전시보다는 참여형 전시가 전시의 이해도를 높이고, 기억에 오래 남는 다는 점에서 더 선호하다는 설문조사 결과를 얻게 되었다. 그리고 직접 작품제작에 참여한다면 뮤지엄에 방문할 의향이 높게 나왔다. 현대 뮤지엄에서 어떤 식의 참여적 전시가 행해지는지를 문헌조사와 직접 전시 관람을 통해서 조사해보고, 이를 전시를 보기 전과 전시를 보는 중 그리고 전시를 본 후의 여정에 따라 관람객들이 어떻게 전시에 참여를 하는지를 예시를 통해 분석해 보았다. 관람객이뮤지엄에 전시가 열리기 전에 관람객이 작품 제작에 참여하는 경우가 있다. 전시 관람 중에 뮤지엄에서 관람객의 참여를 유도하기 위해 어떤 시도를 하는지 알아보고, 뮤지엄에서 시행하는 워크샵을 통해서 관람객의 참여 방식을 조사해 보았다. 자본의 유입으로 평소에 할수 없었던 새로운 경험을 관람객에게 제공하고, 기술의발전으로 가능한 인터랙티브한 작품으로 전시에 참여할 수 있다. 마지막으로 전시 관람 후에 느낀 감상평이나 정보를 공유하거나 리뷰하면서 전시의 한 부분으로참여를 할 수가 있다. 참여적 전시에 대한 관심과 연구로 사회적 교류가 이뤄지는 뮤지엄으로 발전해 갈 수있다. 향후 이 논문을 바탕으로 관람객이 참여할 수 있는 전시를 기획하고, 전시를 해보고자 한다.

TPM3유전자 이형접합 과오돌연변이에 의한 캡근병증

정유리,박영은,신진홍,이창훈,김대성 대한신경과학회 2016 대한신경과학회지 Vol.34 No.3

Cap myopathy is pathologically characterized by cap structures comprising well-demarcated areas under the sarcolemma and containing deranged myofibrils and scattered Z-disks. Clinically it presents with slowly progressive muscle weakness, myopathic face, and frequent respiratory insufficiency. Four genes have been reported to be associated with the disease: TPM2, TPM3, ACTA1, and NEB. Here we describe that a patient presenting with mild limb weakness with facial affection showed cap structures on muscle pathology and carried a heterozygous TPM3 mutation.

Diabetic Retinopathy and Related Clinical Practice for People with Diabetes in Korea: A 10-Year Trend Analysis

정유리,하경화,이기황,김대중 대한당뇨병학회 2020 Diabetes and Metabolism Journal Vol.44 No.6

We performed a retrospective cohort study including people diagnosed with diabetes from 2006 to 2015 according to the Korean National Health Insurance Service-National Sample Cohort database, to analyze the changes in the prevalence, screening rate, and treatment patterns for diabetic retinopathy (DR) over 10 years. The proportion of people who underwent fundus screening for DR steadily increased over the past decade. The prevalence of DR increased from 13.4% in 2006 to 15.9% in 2015, while that of proliferative DR steadily decreased from 1.29% in 2006 to 1.16% in 2015. The proportion of patients undergoing retinal photocoagulation constantly decreased. The prevalence of DR increased over the past decade, while its severity seemed to have improved, with a decreased rate of proliferative DR and retinal photocoagulation. A higher proportion of patients underwent ophthalmic screening using fundus examination, but still less than 30% of patients with diabetes underwent comprehensive examination in 2015.

개정판 외상 사건에 대한 아동 반응척도의 요인타당도 및 정신측정학적 성질 연구

정유리,김대호,김석현,고복자,김선현,배활립 대한신경정신의학회 2012 신경정신의학 Vol.51 No.4

이 연구는 최근 외상을 경험한 초등학교 고학년을 대상으로 K-CRTES-R의 신뢰도와 타당도를 입증하여 한국 학령아동들에게 유용하게 쓰일 수 있는 도구임을 시사받았다. 저자들은 2주 검사-재검사, 내적 일치도, 수렴 및 구별 타당도,요인타당도에서 우수한 수준의 결과를 보고하는 바이다. Objectives Posttraumatic stress disorder (PTSD) in children is prevalent and often persists for many years after the trauma. Therefore, screening and early detection using psychometrically sound instruments is a pivotal element of appropriate management. This study tested the reliability and validity of a Korean version of the Child Reaction to Traumatic Events Scale-Revised (K-CRTES-R) in a sample of recently traumatized school children. Methods The K-CRTES was administered to a total of 464 school children aged ten to twelve who had witnessed or had been confronted with a tragic accident involving three deaths. Internal consistency, two week test-retest reliability, and construct validity were assessed. A non-random portion of participants also completed the State Anxiety Inventory and the Subjective Unit of Distress Scale for testing convergent validity. Exploratory factor analysis was conducted for a random half of participants (n=232), and, for the remaining half, we tested the model fit by performance of confirmatory factor analysis. Results Two week test-retest reliability was high (r=0.85), and internal consistency was excellent (Cronbach α=0.92). The total score for the K-CRTES-R showed significant correlation with state anxiety and subjective level of anxiety, thus confirming its convergent validity. In addition, the K-CRTES-R distinguished between direct exposure and indirect confrontation, demonstrating the discriminant validity of the scale. In addition, we confirmed the factorial validity by identifying a two-factor structure (intrusion-hyperarousal and avoidance) that explained 56% of the total variance. This two factor solution and other previously suggested PTSD models showed fit indices that were within an acceptable range. Conclusion Findings of our study indicate that the K-CRTES-R is a good measure of reliability and validity that can be used to assess the impact of trauma in Korean speaking children.

편두통 환자에서 비두통기 상부위장관운동장애

정유리,황민호,강규식,권오현,박종무,이정주,조윤주,김병건 대한신경과학회 2011 대한신경과학회지 Vol.29 No.4

Background: Nausea and vomiting are predominant accompanying symptoms of migraine attacks. Although the underlying mechanism is not yet clear, gastric stasis is assumed to be the main factor. However, few studies have used direct methods to establish delayed gastric emptying of migraine patients. We compared interictal gastric motility between migraine patients and normal controls with the aid of gastric scintigraphy. Methods: The study population comprised patients who had been diagnosed with episodic migraine, according to the International Classification of Headache Disorders, edition II. The entire study population was completely free of gastrointestinal symptoms during the headache-free period. Gastric scintigraphy was performed to determine the time to half emptying (T1/2 ) and the percentage of radioactive material remaining in the stomach (%RMR) at 30, 60, 90, and 120 min. Results: Twenty-six migraine patients and 12 normal controls were recruited. The mean T1/2 did not differ between the two groups (101.8 vs 95.2 min; p=0.432). The %RMR values in the stomach at 30, 60, 90, and 120 min also did not differ significantly between the two groups [87.5% vs 88% (p=0.900), 70.8% vs 71.2% (p=0.950), 54.2% vs 53.3% (p=0.753), and 39.0% vs 37.3% (p=0.583), respectively]. Conclusions: There is no gastric stasis in patients with episodic migraine during headache-free periods. Our results suggest that the main mechanism underlying the nausea and vomiting in migraine patients is not a gastric stasis in interictal periods, but rather a central process, as a result of changes occurring in the brainstem during acute migraine attacks.

독일 동포 어린이에게

정유리 한국국어교육학회 2000 세계가 한동네 Vol.2000 No.-

수면심도를 달리하여 전신마취를 받는 환자에서 처리해리절차를 이용한 기억형성 평가

정유리,최병문,노규정 대한마취통증의학회 2018 Anesthesia and pain medicine Vol.13 No.4

Background: Process dissociation procedure has been used to evaluate explicit and implicit memories. Two process-dissociation measurement models are described. Methods: This prospective study evaluated intraoperative memory formation in Korean patients undergoing elective surgery under general anesthesia and its relation to the depth of hypnotic state. A total of 270 patients enrolled were randomly assigned to three groups based on Bispectral Index (BIS) values in the following ranges: 30 to 40, BIS 40 to 50, and BIS 50 to 60 according to the level of hypnotic depth induced by propofol or sevoflurane during the presentation of wordlists. When the level of hypnotic depth was maintained at the target BIS range, words were played for 15 minutes via headphones to patients. Within 24 hours after the word presentation, memory was assessed using an auditory word stem completion test. The probability of explicit and implicit memory was calculated using original and extended measurement models. Brice interviews were performed within 1 and 24 hours after surgery. Results: A total of 119 patients who did not deviate from the target BIS range were included in the analysis. The 95% confidence interval (CI) of the probability of occurrence of implicit memory evaluated by the original model did not include zero. However, when the extension model was used, 0 was included in the 95% CI. Explicit memory evaluated via Brice interviews did not occur in any group. Conclusions: When BIS was maintained in the range of 30 to 60 during surgery, no explicit or implicit memory was observed.