소아기관지 천식에서 연령별 알레르기 지표에 관한 고찰

정용헌 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

To evaluate allergic paramenters according to age, 90 cases of asthmatic children seen in pediatric department of Chungnam National University Hospital, followed up for more than 5 months of period, were studied. Study groups were divided into 4 by age as below 2, 3-5, 6-8 and over 9 years. In allergic parameters, concordance with allergic rhinitis, blood total eosinophil count, serum IgE level and skin sensitivity to common allergens were encountered. The results were summarized as follows : 1. The most frequent attendance age to hospital for asthma was between 3-5 years, then 0-2, 6-8, over 9 years in order. 2. Onset of asthma under 6 years of age encountered in 74.4% of asthma, noted mostly in age between 3-5 years and rarely over 9 years of age. 3. The concordance rate of asthma with allergic rhinitis was 56.7%, noted mostly in age between 6-8 years and leastly below 2 years. 4. Blood total eosinophil counts were mildly elevated in 33.3%, highly in 44.4% of asthma, low in age between 0-2 years and high between 6-8 years. 5. Serum total IgE levels were mildly elevated in 27.9%, highly in 43.0%, low more than half in age below 2 years and high more than half of cases over 3 years. 6. The degree of skin sensitivity to common allergens was weaker in age below 2 Fears than over 3 years. Above results may be suggested the differences of allergic parameters by age and required to be estabilished the different standards of allergic parameters by age, especially for infant below 2 years of age.

소아 천식의 혈청 총 IgE치의 변화에 관한 연구

정용헌 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

A study was performed to evaluate a change of the different serum total IgE values in childhood bronchial asthma with long-term immunotherapy. Study subjects were 36 cases in total and divided into 4 groups according to the differences of IgE values as below 200, 201-500, 501-1000, over 1001 IU/ml. Serum total IgE were measured on 3 occasions every 6 to 12 month interval. The results were summarized as follows. 1. No significant change was noted in IgE values of below 200 IU/ml groups during the study period. 2. A significant change was noted in IgE values of 201-1000 IU/ml groups between 1st & 3rd study. 3. A significant change was noted in IgE values of 501-1000 IU/ml groups between 1st & 2nd, 1st & 3rd study. 4. A significant change was noted in IgE values of over 1001 IU/ml groups between 2nd & 3rd, 1st & 3rd study 5. A significant change was noted in IgE values of all groups between 1st & 3rd study.

정상 소아의 폐기능에 관한 연구 : 초등학교 아동의 PEFR 및 MMFR 검사치의 비교

정용헌 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

Normal values of lung function are very essential for analysis of pulmonary functional status. Their values are variable depend on tool of measurement. Each parameter showing pulmonary function is variable depend on effortness of subjects to be studied. Hereby, this study was done to encounter the spirometric distribution of normal children, assesed by health questionair and physical examination and also to determine which two spirometric parameters represent the value more useful. The results were summarized as follows: 1. PEFR values were widely distributed in range from below 49% to over 130% and total number below 59% encountered in 18(5.8%), and below 49% in 6(1.9%). 2. MMFR values were also widely distributed in range from below 49% to over 130% and total below 59% to encountered in 42 cases(13.6%), and below 49% in 4 cases(1.3%). In conclusion, PEFR and MMFR values were widely distributed in range below 49% and over 130%. MMFR is more useful for mass screening tests than PEFR in predicting the normal pulmonary function, measured by spiroanalyzer ST-250.

소아 비만증의 진료

정용헌 한국의학사 1984 診斷과治療 Vol.4 No.5

영아기 히스타민 농도별 피부 반응도의 평가

정용헌,이훈영 대한 소아알레르기 및 호흡기학회 2001 소아알레르기 및 호흡기학회지 Vol.11 No.2

기관지 천식 환아에서 면역 요법에 의한 혈청 총 IgE 치의 변화

정용헌 대한소아알레르기호흡기학회 1995 Supplement Vol.5 No.1

N/A

地域社會 小兒 豫防接種實態에 關한 調査

鄭鏞憲,洪春實 충남대학교 의과대학 지역사회의학연구소 1978 충남의대잡지 Vol.5 No.1

The present work was performed to clarify the current status of immunization among infant and children in Urban area. In autumn, 1977, a survey was conducted towards 323 women residing in 35 Dongs in Dae-Joen City. 323 housholds were selected randomly in each Dong and home visiting interviews were carried out by medical students with questionairs designed to measure various immunization status of children under 3 year of age. The results were summarized as follows; 1. The majority of respondents was mostly familiar to measles, poliomyelitis, D.P.T. and small pox vaccines but unfamiliar to mumps at all. 2. Maternal familiarity to immunizations was related to the age of their children. 3. The performance of immunizations by age of children was variable to types of vaccines. 4. 91.6% of children surveyed was vaccinated againest D.P.T., 87.0% against poliomyelitis and 58.8% againest B.C.G. 5. The immunization rates among children aged 13 to 36 months were shown in measles, small pox, encephalitis, mumps, typhoid, with 75.6, 62.6, 34.6, 29.0, 25.8% respectively and mean of 45.5%. 6. As for places of immunizations, 68.6 % of group surrveyed, took immunization at hospital, 23.8% at health center, 1% at pharmacy and 6.6% in others. 7. The major reasons for failure of immunizations were ignorance and idleness. 8. Of the 3rd immunization rate, D.P.T. and polio marked 51.7 and 45.9% respectively and those booster were 3. 7 and 4. 3% only. 9. D.P.T. and polio immunization rates by frequency of injection were shown higher in high school graduates, and those rates by age similar in all age groups except 3∼7 month group. 10. The higher were the mother's educational level and living standard, revealed the higher the immunization rates at hospital. 11. Of the place for immunization by frequency of injection, 3rd immunization rate was very low at health center. 12. As for adequate time to be vaccinated, the immunization rate of B.C.G. within 1 month of age showed 37.8%, that of small pox during l to 2 year of age 53.8%, and that of measles in 12 month of age 37.8%.

소아천식에서 Histaglobulin의 반응요인에 대한 연구

정용헌 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

During the period of Jan. 1984 and June 1987, author studied 34 cases of asthmatic children evaluated in department of pediatrics, Chungnam. National University Hospital for 1 year or more to predict the effective factors to histaglobulin for treatment of bronchial asthma in childhood. The results are summarized as followings. 1. The favorable factors suggestive of response to histaglobulin were followings as young age below 6 year old, short duration of disease less than 1 year, negative allergen test and low value of IgE less than 200 IU. 2. The factors as accompaning allergic disorders, severity of disease, family history of allergy and blood eosinophil value were not indicated to predict the effect of histaglobulin for bronchial asthma.

기관지 천식 환아에서 면역 요법에 의한 혈청 총 IgE 치의 변화

정용헌 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

To clarify any change of serum total IgE values by immune therapy in childhood bronchial asthma, author investigated 44 children with bronchial asthma seen in pediatric department of Chungnam National University Hospital, being followed up for more than 12 months of period. Study subjects were divided into 2 groups depend on immune therapy, such as non-immune therapy, 20 cases and immune therapy, 24 cases in number. Total IgE were measured by PRIST method in serum, twice apart from 1 year over in both groups. The result was concluded as a significant difference of serum total IgE value between 2 groups with nonimmune- and immune-therapy.

Mycoplasma Pneumoniae 폐렴 환아에서의 Polymerase Chain Reaction 법과 혈청학적 검사법의 상관성에 관한 연구

정용헌,임혜경 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

A study was done on 58 cases of children with pneumonia, admitted to the pediatric department of Chungnam National University Hospital during the period of 9 months from Feb. to Sept. 1997, in age between 2 years and 12 years, to confirm the correlation between mycoplasma antibody, cold agglutinin and PCR test. The results were as followings. 1. The total numbers of PCR positive to mycoplasma pneumoniae were 30 cases and those of PCR negative 28 cases. 2. In PCR positive group, distribution of cold agglutinin values over 1:64 and below 1:32 showed 56.7% and 43.4% in early stage, those values 94.5% and 5.6% respectively in later stage. Distribution of mycoplasma antibody over 1:160 shoved 60% and below 1:80 40% in early stage, 1005 and 0% in later stage. 3. In PCR negative group, cold agglutinin values showed wide ranges of 1:2 to over 1:64, mycoplasma antibody showed mostly below 1:40. 4. In PCR positive group, mycopasma antibody values were correlated with cold agglutinin value in later stage It's concluded that PCR test in highly correlated with mycoplasma antibody test.