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This is the clinical statistics of 159 cases of hematologic disorders which were selected from 3611 patients under 15 year of age admitted in pediatric ward of Chung Nam National University Hospital during the period of 7 years from Jan. 1973 to Dec. 1979. Diseases are classified by international classification of diseases. The results were summarized as follows: 1. The ratio of hematologic disorders to total number of admitted cases was shown increasing tendency year by year as 4.4% in total, 1.8% in 1973, 3.3% in 1974, 4.9% in 1975, 3.8% 1976, 5.0% in 1977, 4.9% in 1978 & 5.2% in 1979. 2. Male to female ratio was 2 to 1. 3. The number & raito of hematologic disorder by age group were 66(41.5%) in 6-12 years, 42(26.4%) in 12-15years, 33(20.7%) in 2-6years, 10(6.2%) in 0-1year group & cases(5.0%) in 1-2years old group in order. 4. The age incidence of hematologic disorders was the most in 12-15years as 10.5% & the least in 0-1year old group as 0.8% of comparable age group of inpatient. 5. The most frequent group & single entity of hematologic disorders was neoplasm, the next anemia, purpura & coagulopathy & was acute lymphoblastic leukemia in neoplasm, aplastic anemia in anemia, allergic purpura in purpura & methemoglobinemia in other group. in or der. 6. Based on review of 9 articles surveyed in various hospitals of Korea, Neoplasm, anemia, purpura and others were encoun tered in order of frequency.
From Jan. 1979 to June 1981 authors studied on the characteristics of fourty five newborn infants with non-hemolytic jaundice admitted in pediatric ward of Chung-Nam National University Hospital following phototherapy. The results were summarized as follow; 1. Incidence was male predominant with male to female ratio being 2. 5 to 1. 2. Wide variations of birth weights and gestational age were noted ranging of 1800 to 4350gm and 34 weeks with average of 2902.4gm and 39.96 weeks. 3. The level of total bilirubin in serum at admission was the most frequently encountered in 15.0 to 20.0 mg% and 30.1% in 20.1mg% and more group. 4. 35.6% of cases had jaundice less than 3 days while 64.4% more than 4 days before hospitalization. 5. The smaller the birth weight was, the higher the billirubin level and the number of cases noted. 6. The younger the gestational age was, the higher the bilirubin level and prematurity rate observed. 7. Decreasing tendency of the total bilirubin level by weight with phototherapy was remarkably high for the first 24 hour and diminished with time and the smaller the birth weight was, the more the decreasing rate of it demonstrate in all groups. 8. Decreasing tendency of the total bilirubin level by its severity with phototherapy was significantly high for the first 24 hours and with increasing bilirubin level and diminished with time in all groups.
The following results were obtained through the clinical review of 77 cases of meningitis seen at ward of the pediatric department of Chungnam National University Hospital during the period of 3 years from Jan. 1979 to Dec., 1981. 1. The annual incidence was not decreased. 2. School period was the most frequent age group in aseptic, on the other hand, early infancy period in tuberculous and pyogenic meningitis. 3. Male was predominant both in aseptic and pyogenic meningitis. 4. The most common chief complaint was headache in aseptic and conscious deterioration in tuberculous and pyogenic meningitis. 5. Duration of present illness was less than 10 days in aseptic and pyogenic meningitis In some cases of tuberculous meningitis, it's over 10 days. 6. Duration of admission was within 20 days in aseptic and over 21 days in some of pyogenic and tuberculous meningitis. 7. Predromal symptoms were U. R. I. and mumps in aseptic, pulmonary tuberculosis in tuberculous, and pneumonia, sepsis, etc. in pyogenic meningitis. 8. On peripheral blood findings; 1) Hematocrit value below 30% and hemoglobin below 10gm % were more encountered in aseptic and tuberculous than in pyogenic meningitis. 2) Leukocytosis was often noted in pyogenic, increased E. S. R. in tuberculous and pyogenic meningitis. Leukocyte differential count was not characterized in any types of meningitis. 9. On C. S. F. findings; 1) Pleocytosis over 1001/㎣ was noted in half of pyogenic but few in tuberculous and aseptic meningitis. 2) Sugar level below 20mg % was not, encountered in aseptic but detected in each 44% of tuberculous and pyogenic meningitis respectively. 3) Protein level over 101mg % was not encountered in aseptic but detected in 25% of tuberculous and 31% of pyogenic meningitis. 4) Positive pandy reaction was rarely noted in aseptic but quite frequently in tuberculous and pyogenic meningitis. 5) No micro-organisms were isolated in aeptic, tuberculous and most pyogenic meningitis. 6) Cloudiness were mainly seen in pyogenic: meningitis. 10. All cases of aseptic meningitis were recovered without complication or sequelae while some of tuberculous and pyogenic meningitis either expired or discharged without improvement.
A study was performed to evaluate the usefulness of methacholine challenge test in preschool children unable to perform the spirometry 45 cases were selected from patients complaining frequent respiratory illness, seen in ourpatient clinic of pediatric department, Chungnam University hospital during the period of Aug. 1994 to July 1996. The results were summarized as follows: 1. The values of methacholine concentration showing PC20 were widely distributed as reange of 0.3mg/ml to 25 mg/ml, not 50 mg/ml. 2. Methacholine mean value inducing cough was 1.25mg/ml in under 6 year of age, 2.5mg/ml in over 6 year of age. 3. Methacholine mean value inducing wheezing was 5 mg/dl in under 6 year of age, 10mg/ml. in over 6 year of age. 4. Methacholine concentrations showing PC20 values induced by methacholine challenge were more compatible with those of wheezing than cough. 5. Wheezing and cough were not correlated in methacholine challenge test With the results, a significant association was found between bronchial responseiveness to methacholine and wheezing checked by ausculation. Clinical manifestation, as wheezing, by methacholine challenge, can be predictable for pulmonary function value in preschool children without spirometry.
This is the clinical statistics on 3260 diseases of in-patients admitted in pediatric ward of Chung Nam National University Hospital during 6 years from Jan. 1973 to Dec. 1978. Diseases are classified by international classification of diseases, age, sex and month. This figure do not take account of normal newborn infants and children abmitted to other departments. The results are concluded as follows ; 1. On age distribution, school age group was the most 739(22.67%), pre-school 695 (21.32%), adolescent 367(11.16%). and late infancy 271(8.32%) in order. 2. On number of patient by month, September was the most, November, December, April in order. 3. Male to female ratio was 3 to 2. 4. The number of male was remarkably high in group of birth to 1yr. and 12 to 15 yr. of age. 5. The 10 leading causes of hospitalization by system were infectious & parastic (32.87%), Respiratory(16.59%), Ill defined(10.45%). Perinatal(8.02%), Nervous(7.56%), Urinary(4.45%), Congenital anomaly(3.78%), Circulatory (2.98%), Blood(2.88%) and Neoplastic diseases(2.67%) in order of frequency. 6. The 10 leading causes of hospitalization by diseases were Pneumonia(7.91%) Prematurity(6.38%), Acute upper respiratory infection(6.01%), Diarrheal disorder(5.8%), Meningitis (4.45%), Tbc meningitis (3.56%), Sepsis(2.58%), Epidemic encephalitis(2.55%), Acute nephritis(2.21%), Congenital heart disease(2.06%) in order of frequency. 7. The frequency of infectious disease was the most in all age except neonatal period, the next respiratory disease in age of 1 month to 12 year and genitourinary system after 12 year of age. 8. Epidemic encephalitis, Diarrheal disorder, Diphtheria, Acute Niephritis and Pneu monia have a tendency of seasonal prevalence. 9. The frequency of Neoplasm or Nervous disorder was predominant in male while that of mental disorder being high in female.
Statistical analysis of 180 fatal children among 2184 in-patients who were ohserved in the pediatric department, excluding nursery, of Chungnam National University Hospital during the past 15years from Jan. 1st, 1973 to Dec. 31st, 1977was carrried out on fatality by year, month, sex, and age, number of fatel cases by duration of hospitalization and es of diseases by age and year. The results were summerized as follows; 1. Total number of admission during 5 year perod was 2184 with the ratio of male to female being 1. 1 to 1. 0. 2. The fatality rate of in-patients by year was 8. 2% with range of 6. 3 to 9. 7%. 3. Seasonal Prevalence of fatality was seen high in summer, and low in winter. 4. Fatality of male is slightly higher than that of female. 5. The younger the patient was, the higher showed the fatality. 6. Fatality by duration of hospitalizatin was revealed highest on 1^st day of almission and decreased steadily thereafter. 7. The frequent leading causes of death by system were infectious diseasls, 41. 1% of total fatal cases, diseases of the respiratory system, congenital anomaties, blood disorders, and diseases of nervous system in order of frequency. 8. Major diseases causing death were meningitis, pneumonia, encephalitis, diphtheria, encephalopathy in order. 9. As for causes of death by age, tetanus in neonatal period, sepsis in early infancy, dysentery in late infancy, encephalopathy in preschool period, encephalitis both in school and adolescent period were the most frequently encountered.
Normal values of various pulmonary function tests are very essential for analysis of pulmonary function. Factors influencing on normal lung function values need to be clarified. The one-second forced expiratory volume(FEV1), forced vital capacity(FVC), maximal mid-expiratory flow(MMF) and peak expiratory flow(PEF) of 260 healthy school children from 7 to 12 years of age were measured by using a computerized spirometry. The results of pulmonary function tests were demonstrated for each height group(10cm interval), age and sex. The value of spirometric measurements were different by height, age and sex. Height was a more reliable index of pulmonary development than age or sex.
The authors studied on 77 children with acute hepatitis who admitted to the pediatric department of Chungnam National University Hospital during the period of 2 years from April 1982 to March 1984 to observe frequency of Hepatitis B antigen & antibody and to analysis any differences between B and Non-B marker groups by age, sex, living place, duration of hospitalization and various lab. parameters. The results are summarized as follows: 1. Positive rates of HBs Ag., HBs Ab., HBc Ab. and HBe Ag. tested seperately were encountered in 20.8, 15.6, 29.9 and 14.3% respectively. 2. In cases tested both HBs Ag. & HBs Ab., positive rates of HBs Ag. or HBs Ab. and both were 16.9, 11.7 and 3.9%. 3. In cases tested HBs Ag., HBs Ab. and HBc Ab., positive rates of HBs Ag. or HBcAb. were 5.2 & 6.5%, those of HBs Ag. & HBc Ab. or HBs Ab. & HBc Ab. being each 11.7%, those of HBs Ag., HBs Ab. & HBc Ab. being 3.9%. 4. In cases tested HBs Ag., HBs Ab., HBc Ab. and HBe Ag., negative rates of HBs Ag or HBc Ab were 2.6% and 6.5% and positive rates of HBs Ag & HBc Ab being 3.9%, those of HBs Ab. & HBc Ab. being 3.9%, of HBs Ab. & HBc Ab. being 11. 7%, of HBs Ag, HBc Ab. & HBe Ag. being 7.8%, of HBs Ag. and HBeAg. 2.6% and of all antigen & antibody being 3.9%. 5. Hepatitis B marker demonstrated higher in older than younger age groups. 6. Childhood Hepatitis were more frequently occurred in boys than in girls and in urban than in rural area. 7. Duration of hospitalization is more prolonged in B-marker positive than in negative groups.
To know the children with frequent respiratory infection on their atopic status and the relation between total IgE and HDM IgE, author measured serum total IgE and DP- & DF-IgE of 91 children with frequent repiratory infection seen in out-patient department of pediatrics of Chungnam National University Hospital. The results were as follows; 1. Total number of cases with serum T-IgE above 250 IU was 33(36.3%) 2. Total number of cases with serum DP-IgE below +1, & above +2 were 68 (73.7%), 23 cascs(25.3%) respectively, those of DF-IgE below +1 & above +2 were 67(73.6%), 24(26.4%) respectively. 3. Total number of cases with serum T-IgE below 249 lU & DP-IgE below +1 was 53(58.3%),those with serum T-IgE above 250 IU & DP-IgE above 2 + was 18.(19.8%) 4. Total number of cases with serum T-IgE below 249 IU & DF-IgE below +1 was 55(60.4%),those with serum T-IgE above 250 IU & DF-IgE above 2+ was 21(23.1%). Above results suggested that frequent respiratory infection was closely related with atopy, specific lgE showed negative or +4 mostly, and DP- & DF-IgE values were very similar.