초등학생 독서치료 프로그램 관련 학위논문의 동향 분석: 2003-2010

정수연,이명규,Jung, Soo-Youn,Lee, Myoung-Gyu 한국비블리아학회 2011 한국비블리아학회지 Vol.22 No.3

This study analyze the process of bibliotherapy, the typical problems of participant, and the trend on books of bibliotherapy, using the theses about clinical bibliotherapy program for Elementary School Students from 2003 to 2010 in Korea. Bibliotherapy has been studied at various academic fields. And the bibliotherapy process for all steps of readiness, comprehension-building, and evaluation is more effective in clinical bibliotherapy. Typical problems and contents of participant deal with a lack of sociality, a lack of self-conception and self-esteem, depression, a feeling of uneasiness, and desultory attitude of learning as the problems of psychosocial risk or mental disorders. And also, bibliotherapist need to develope suitable list of books for the typical problems of participant. The study is to present basic data for clinical bibliotherapist and researcher and to indicate the direction of their study in the future.

조선후기 탈춤 연행구조에 관한 연구-광대, 향리 집단을 중심으로-

정수연 ( Soo Youn Jung ),전은자 ( Eun Ja Jun ) 대한무용학회 2006 대한무용학회논문집 Vol.47 No.-

간호학생을 위한 당뇨병 방탈출 시뮬레이션 개발 및 적용: 예비연구

정수연(Soo Youn Jung),김영진(Young Jin Kim),문경자(Kyoung Ja Moon) 계명대학교 간호과학연구소 2024 계명간호과학 Vol.23 No.2

Purpose: Given managing blood sugar levels is crucial for preventing complications in diabetes, development of an effective diabetic program is essential. Incorporating games into nursing education has been considered as a strategy to enhance motivation and active participation. This pilot study aimed to develop and implement a diabetes simulation program using escape rooms. Methods: This program was designed the program title, educational objectives, and educational operation methods. Participants included 30 third- and fourth-year nursing students. They completed missions involving solving puzzles, finding passwords, and locating answer cards across three rooms themed around understanding, treating, and managing the lifestyle habits associated with diabetes. After completing the escape rooms, data were collected through telephone interviews with eight participants. The experiences and perceptions of the program were analyzed using the phenomenological approach. Results: We found three key themes: collaborating with team members, new learning methods for major subjects, and expectations for broader applications of escape rooms in nursing education. Conclusion: The escape room approach is an effective nursing education method that enhances learners’ motivation and satisfaction. Further studies with larger sample sizes are needed to validate these findings and evaluate their broader applicability.

요양병원 내 경도인지장애 환자의 섬망 발생 영향 요인: 예비연구

정수연(Soo Youn Jung),현용환(Yong Hwan Hyeon),문경자(Kyoung Ja Moon) 계명대학교 간호과학연구소 2023 계명간호과학 Vol.22 No.2

Purpose: This study was conducted to identify factors that affect the occurrence of delirium in patients with mild cognitive impairment hospitalized in long-term care facilities. Methods: This study analyzed data collected from 2 long-term care facilities. A cross-sectional pilot study was conducted with 42 patients aged 65 years or older and mild cognitive impairment. To identify factors influencing the occurrence of delirium, multiple logistic regression analysis including general characteristics, risk-related, and medical characteristics was performed. Results: Delirium occurred in 14 (33.3%) of the participants. Hypoactivity was seen in 6 participants (42.86%), hyperactivity in 7 (50.0%), and a combination of both aspects in 1 (7.14%). The results of multiple logistic regression analysis showed that delirium in patients with mild cognitive impairment in long-term care facilities had a high occurrence in patients wearing diapers. Conclusion: This study identified the occurrence of delirium in patients with mild cognitive impairment hospitalized in long-term care facilities. One of the factors affecting the occurrence of delirium was “wearing diapers.” The findings can be used to train nurses on delirium evaluation and intervention and to help prevent and manage delirium in long-term care facilities. This study suggests that further research is necessary to reduce the incidence of delirium.

개 신동맥 내피세포의 무스카린성 및 알파 아드레날린성 수용체에 대한 작용

정수연(Soo Youn Chung),장기철(Ki Churl Chang),임정규(Jung Kyoo Lim) 대한약리학회 1989 대한약리학잡지 Vol.25 No.1

내피세포가 잘 보존된 개 신동맥에서 Phenylephrine으로 전 수축시킨 후 Actylcholine을 투여하면 혈관 이완을 관찰할 수 있었지만 내피세포를 파괴시킨 개 신동맥에서는 혈관 이완을 관찰할 수 없었으므로 내피세포가 혈관 이완에 관여함을 알 수 있었다. 그래서 내피세포에서 분비되어 혈관 이완을 촉진하는 물질을 Endothelium Dependent Relaxation Factor (EDRF)라고 한다. Acetylcholine에 의한 혈관 이완은 Atropine에 의해 경쟁적으로 억제되었으므로 Muscarinc 수용체의 자극을 받아 EDRF가 분비되고 이것이 평활근에 작용하여 이완을 일으킬 것으로 생각되었다. EDRF의 작용기전을 알아보기 위해 용해성 Guanylate cyclase 억제제인 Methylene blue를 전처치 했을 때는 Acetylcholine 뿐 만 아니라 Sodium nitroprusside에 의한 이완도 억제되었다. 그러나 Prostacyclin에 의한 이완은 억제되지 않았다. 이 결과로 판단 해 보면 EDRF에 의한 이완효과가 Cyclic GMP와 관련이 있을 것으로 생각되었다. 한편 Thromboxane A₂ 유사체인 U-46619로 전수축 시킨 후 Alpha-2 아드레날린성 항진제인 Clondine을 투여했을 때 혈관 이완은 일어나지 않았다. 수축의 억제 양상에 있어서 Alpha-1 아드레날린성 항진제인 Phenylephrine보다 Clonidine이 더 효과적 이었다. 이상의 결과를 기초로 하여 다음과 같은 결론을 얻을 수 있었다. 1) Muscarinic 수용체의 자극을 받아 EDRF의 분비가 촉진된다. 2) Alpha-1 아드레날린성 수용체와 Alpha-2 아드레날린성 수용체가 개 신동맥에 존재한다. 3) EDRF에 의한 이완이 Methylene blue에 의해서 억제되므로 cGMP를 이용한 기전 임을 알 수 있었다. Responsiveness of muscarinic and alpha adrenoceptor activation on endothelial cells was studied in isolated canine renal artery rings. Ach (10-100 nM), dose dependently, relaxes endothelial intact rings precontracted with phenylephrine (IC₅₀ of Ach was 34.5 nM). Selective mechanical destruction of the endothelium transformed the activity of this substance from vasodilatation to vasoconstriction. Acetylcholine induced relaxations could be selectively inhibited competitively by atropine, but could not be inhibited by cyclooxygenase inhibitor. Methylene blue, however, an inhibitor of soluble guanylate cyclase activity, inhibited Ach as well as sodium nitroprusside (SNP) induced relaxation. Relaxation produced by prostacyclin was not modified by methylene blue. On the other hand, alpha adrenoceptor agonist did not relax but contract canine renal artery rings possessing an intact intima precontracted with U-46619. Clonidine, however, selective alpha-2 adrenergic agonist, is more susceptible than phenylepherine, selective alpha-1 adrenergic agonist, to the inhibitory effect of contraction. These results suggest that in canine renal artery rings, 1) muscarinic receptor is responsible for releasing endothelium dependent relaxation factor (EDRF). 2) alpha-1 and alpha-2 adrenergic receptors are present in canine renal artery. 3) relaxation via EDRF is antagonized by methylene blue, providing further evidence that EDRF acts through a cGMP mechanism.

일반인에서의 의약품 부작용보고제도 인식도

안소현 ( So Hyeon Ahn ),정수연 ( Soo Youn Chung ),정선영 ( Sun Young Jung ),신주영 ( Ju Yeon Oh ),박병주 ( Byung Joo Park ) 한국보건행정학회 2014 보건행정학회지 Vol.24 No.2

Background: Safety of drugs has become a major issue in public healthcare. Spontaneous reporting of adverse drug reaction (ADR) is the cornerstone in management of drug safety. We aimed to investigate the awareness and knowledge of spontaneous ADR reporting in general public of Korea. Methods: A total of 1,500 study subjects aged 19-69 years were interviewed with a questionnaire for their awareness and knowledge related to spontaneous ADR reporting. Computer assisted telephone interview was performed from 27th February 2013 to 4th March 2013. Target population was selected with quota sampling, using age, sex, and residence area. Healthcare professionals such as physicians, pharmacists, and nurses were excluded. The survey questions included awareness of spontaneous ADR reporting, opinions on ways to activate ADR reporting, and sociodemographic characteristics. Results: Overall awareness of spontaneous ADR reporting system was 8.3% (±2.53%) among general population of Korea. Major source from which people got the information regarding ADR reporting was television/radio (69.9%), followed by internet (19.3%), and poster/brochure (6.1%). Awareness level differed between age groups (p<0.0001) and education levels (p<0.0001). Upon learning about the ADR reporting system, 88.5% of study subjects agreed on the necessity of ADR reporting system, while 46.6% thought promotion through internet and mass media as an effective way to activate ADR reporting. Conclusion: The overall awareness of spontaneous ADR reporting should be enhanced in order to establish a firm national system for drug safety. Adequate promotions should be performed targeting lower awareness groups, as well as various publicity activities via effective channels for the general population.

미래 고령사회와 한국형 보건의료체계의 구상 : 일반인에서의 의약품 부작용 보고제도 인식도

안소현 ( So Hyeon Ahn ),정수연 ( Soo Youn Chung ),정선영 ( Sun Young Jung ),신주영 ( Ju Young Shin ),박병주 ( Byung Joo Park ) 한국보건행정학회 2013 한국보건행정학회 학술대회 논문집 Vol.2013 No.2

정보 : 국소 피부용 부신피질 스테로이드제제의 생물학적 동등성 시험 가이던스

정성희 ( Sung Hee Jung ),최선옥 ( Sun Ok Choi ),엄소영 ( So Young Um ),정서정 ( Seo Jeong Jung ),김주일 ( Joo Il Kim ),정수연 ( Soo Youn Chung ) 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.6

After new medical system of separation of dispensary from medical practice was started in 2000 in Korea, to expand bioequivalence-proven drug products and to ensure the credibility of the therapeutic equivalence of generic drugs are hot issues in Korea. It will be obligatory to submit bioequivalence reports for getting licenses of all generic prescription drugs in the near future. Like other countries such as US and Japan, the KFDA also has a plan to re-evaluate the already approved drugs by bioequivalence studies. Therefore, it becomes more necessary to develop bioequivalence-demonstrating methods for specific preparations such as topical drug products among already approved drug products. There are some differences between US and Japanese guidances of bioequivalence studies of generic drug products for topical use. The information on Japanese guidance and the guidance`s Q&As is already provided in our previous paper. In this paper. we examined the US guideline published in 1995 and compared with the Japanese guideline. which will give a useful information to make a guidance on bioequivalence studies of topical drug products in Korea.

정보 : 광학활성의약품 개발과정에서의 입체화학적 문제

최선옥 ( Sun Ok Choi ),정성희 ( Sung Hee Jung ),엄소영 ( So Young Um ),정서정 ( Seo Jeong Jung ),김주일 ( Joo Il Kim ),정수연 ( Soo Youn Chung ) 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.1

Numerous drugs are chiral because they possess one or more chiral centers. Enantiomers may differ in their pharmacokinetic, pharmacological and toxicological properties. However, the significance of stereochemistry of drugs in their therapeutic uses has received relatively little attention until recently. The US FDA issued a guideline on stereoisomeric drugs in 1992, and the European agency describes tests for new drug substances which are optically active in an ICH(International Conference of Harmonization) guideline. According to the guidance, enantiomers may differ in their pharmacokinetic. pharmacological and toxicological properties. Therefore, in this paper, we examined the recently published Canadian guidance, stereochemical issues in chiral drug development, which will be references to make a guidance on stereochemical issues in chiral drug development in Korea.

정보 : 생체이용률에 미치는 음식물의 영향 및 식후 생물학적 동등성 시험

최선옥 ( Sun Ok Choi ),정성희 ( Sung Hee Jung ),엄소영 ( So Young Um ),정서정 ( Seo Jeong Jung ),김주일 ( Joo Il Kim ),정수연 ( Soo Youn Chung ) 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.3

A new medical system was started in Korea in 2000 and pharmaceutical affairs law was revised in 2001. According to the revised law, generic substitution is permitted only to the drug products which are proven to be bioequivalent to the reference listed drugs. To expand the list of bioequivalence-proven drug products and to ensure the credibility of the therapeutic equivalence of generic drug are the hot issues in Korea. Also, the KFDA has a plan to revise the pharmaceutical affairs law that bioequivalence reports of all the generic prescription drug products should be submitted to the KFDA for drug approval after July in 2004. Therefore, it is increasing the necessity to develop the bioequivalence-demonstrating methods for specific drug substances and preparations which require to conduct food-effect bioavailability or bioequivalence study. There are some differences between US and Japanese guidances of food-effect bioavailability and bioequivalence studies. In this paper, we examined the recently published US guidance about food-effect study and it will be a reference to make our own guidance about food-effect bioavailability and bioequivalence guidances in Korea.