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      • KCI등재후보

        급성 국소성 세균성신염의 임상적 고찰

        최은석(Eun Suk Choi),정수룡(Su Ryong Jung),전무련(Mu Ryeun Jeun),이창구(Chang Goo Lee),최형경(Hyeong Kyeong Choi),조욱현(Woo Hyun Cho),이진관(Jin Kwan Lee),김용림(Yong Lim Kim),조동규(Dong Kyu Cho) 대한내과학회 1996 대한내과학회지 Vol.50 No.5

        Objectives: AFBN is a localized bacterial infection of the kidney presenting itself as an inflammatory mass without drainable pus. It is being increasingly recognized by current urographic imaging. It is important not to confuse AFBN with renal abscess or neoplasm as this might lead to inappropriate surgical therapy. This study was per- formed to find out clinical aspects of AFBN. Methods: From Jan. 1992 to Dec. 1993 in Dongkang hospital with a capacity of 600beds, 24cases thought to fulfill the sonographic criteria for AFBN were reviewed retrospectively. Results: 1) The overall male to female ratio was 4:20, and the age distribution ranged from 7 to 78years, and the mean age of overall patients was 35.7±15.9 years. 2) Underlying conditions could be identified in 13subjects(54.2%); pregnancy(N=5), diabetes mellitus (N=2), renal stone(N=2), previous urinary tract infection(N=2), etc. in order of frequency. 3) The duration of preadmission illness was 6.3±5.9 days(1-30). 4) Cardinal symptoms and signs were chills (100%), flank pain(83%), costovertebral angle tenderness(100%), fever(88%), pyuria(88%) and leukocytosis(79%). Urine culture revealed E. coli positive in 10out of 23patients tested: one patient had E. coli positive in blood culture. 5) In total 24 cases, There were two cases accompanying with intrarenal abscesses and one case progressing to intrarenal abscess. 6) All patients were admitted and treated with antibiotics. Fever and flank pain lasted 3.5±0.5 days and 4.1±2.2 days, respectively. No patient underwent surgical procedures. The duration of hospitalization was 8.9±4.4 days(2~20). Conclusion: AFBN is a focal variant of acute pyelonephritis with single area of suppuration. It is not an infrequent disease entity which has relatively good prognosis once diagnosed accurately in its early stage. With delayed treatment or inappropriate therapy, it probably progress to intrarenal abscess.

      • SCOPUSKCI등재

        C형 간염 환자에서 자가항체의 발현빈도

        이진관(Jin Kwan Lee),이장규(Jang Gyu Lee),정수룡(Su Ryong Jung),나인균(In Gyun Na),조종대(Jong Dae Joe),허충(Chung Hur) 대한소화기학회 1997 대한소화기학회지 Vol.30 No.2

        Background/Aims: Various extrahepatic immunologic manifestations was described in patients with hepatitis C virus infection. Among them, the prevalence of anti-tissue antibody have been reported suprisingly high and the presence of autoantibodies such as antinuclear antibody(ANA) and smooth muscle antibody(SMA) requires to differentiate autoimmune hepatitis from chronic hepatitis C. Furthermore these extrahepatic manifestations are triggered by interferon therapy. The presence of autoimmune phenomenon was evaluated in patients with chronic hepatitis C. Methods: Rheumatoid factor(RF), ANA, SMA, and antimitochondrial antibody(AMA) test were done on 43 patients. Six out of them had interferon therapy. Results: One or more of 4 autoan- tibodies were present in 28(65%) patients. RF was found in 7(16%), ANA in 23(53%), SMA in 10(23% ) and AMA in 1(2%). Thirteen with ANA, the fluorescent pattern was speckled in 5(38%), homogeneous in 2(15%), cytoplasmic in 2(l5%), and discrete speckled pattern in 4(31%). Significant proteinuria was not detected. Temporary hyperthyroidism was observed in one with anti- thyroglobulin antibody. In this case, anti-centromere antibody was also detected. Loss of HCV- RNA after interferon therapy was observed in 3 with autoantibody and 2 without autoantibody. Conclusions: The prevalence of anti-tissue antibody was high in patients with chronic hepatitis C. But, other extrahepatic manifestations were rarely observed. The response of interferon therapy was not affected by the presence of autoantibodies. (Korean J Gastroenterol 1997; 30:212-221)

      • SCOPUSKCI등재

        간질로 진단되었던 인슐린종 1 예

        김종수,최은석,허충,최형경,정수룡,이진관 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.3

        Insulinoma is rare functioning islet cell tumor of pancreas and its main feature is frequent attacks of hypoglycemia. Because of frequent seizure, the disease is occasionally mistook as epilepy. We experienced a case of insulinoma with dilantin toxicity in a 45 year old patient who had been treated with dilantin for 7 years. Selective splenic arteriogram showed 0.8cm mass in the tail of pancreas which was proven insulin secreting tumor on histiopathological examination. After operation no more seizure attack was detected and her blood sugar level was well maintained within normal range. This case might provide an insight that the possibility of insulinoma should be considered in patient with episodic neurobehavioral dysfunction such as epilepsy(J Kor Soc Endocrinol 9: 265-271, 1994).

      • SCOPUSKCI등재

        상부 위장관 내시경 검사 시 전처치로서의 Propofol의 효과

        정영호,최정일,이진관,나인균,허충,조종대,정수룡,조삼권 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.3

        Background/Aims: Benzodiazepine is generally used when sedation is required for endoscopy, while propofol, a phenol-derived intravenous anesthetic agent, appears to have a more suitable phamacokinetic profile. The aim of this study was to evaluate the effectiveness and safety of propofol as premedication for upper gastrointestinal endoscopy. Methods: Between July 1998 and October 1998, 44 male patients and 70 female patients were involved in this study. The relative ease of upper gastrointestinal endoscopy, patient's tolerance, and amnestic effects on 64 patients with propofol was compared with 50 patients with non-sedation. Pulse rate and arterial oxygen saturation was monitored. The endoscopist and patients replied to a questionnaire. Results: Patients receiving propofol tolerated endoscopy much more than patients with non-sedation (p<0.01). The change in pulse rate was less variable but arterial oxygen saturation showed a statistically significant decrease in patients receiving propofol (p<0.01). Propofoinduced complete amnesia in 93.7% of the patients and partial anesthesia in 4.7%. Most of the patients receiving propofol accepted the same sedative methods in their next endoscopy (p<0.01). Conclusions: Propofol is highly effective, with a short recovery time and satisfaction of the patients, but careful monitoring is recommended because of its untoward effect of hypoxia. It is recommended that propofol be used as a premedication especially in patients who are apprehensive about a repeated endoscopy.

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