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반복적인 폐구균 감염을 보인8세 남아와 친형에서의 범저감마글로불린혈증
정성훈,안용주,김수연,조병수,김성도,Chung, Sung-Hoon,Ahn, Yong-Joo,Kim, Su-Yeon,Cho, Byoung-Soo,Kim, Sung-Do 대한소아감염학회 2007 Pediatric Infection and Vaccine Vol.14 No.1
범저감마글로불린혈증은 X 염색체에 의해 유전되는 질환으로 주로 1세 이전에 진단이 가능하지만, 진단이 늦어질 경우 반복된 감염 및 중증 감염으로 인한 심각한 후유증을 남길 수 있으므로 조기 진단과 치료가 매우 중요하다. 증상이 다양하게 나타날 수 있으므로 진단을 위한 각별한 주의가 요구된다. 저자들은 반복적이고 심각한 감염의 병력에도 8세가 돼서야 범저감마글로불린혈증 진단을 받은 환아와 그로 인해 함께 진단 받은 친형의 사례를 경험하였기에 보고하는 바이다. Patients with primary immunodeficiencies often have symptoms of their disease for months or years before diagnosis and treatment. This is partly because these disorders are relatively uncommon and the infections typical of immunodeficienciey, for example otitis, sinusitis, and pneumonia, are common. We report a case of agammaglobulinemia in an 8-year-old boy with recurrent and severe infection. He was first seen in our hospital for bacterial meningitis in 2006. His immune status revealed panhypogammaglobulinemia and deficiency in mature B lymphocyte. His elder brother also showed deficiency in mature B lymphocyte but mild hypogammaglobulinemia. Some X-linked agammaglobulinemia (XLA) cases may remain undiagnosed because they only show mild hypogammaglobulinemia and they lack repeated infections in childhood.
악골에 발생한 양성 치성종양의 임상 및 병리조직학적 연구
정성훈(Sung Hoon Chung),이의웅(Eui Wung Lee) 대한구강악안면외과학회 1991 대한구강악안면외과학회지 Vol.17 No.2
The author studied and analyzed on the 56 cases of benign oodontogenic tumor in the jaws which had been diagnosed with biopsy for the period from Jan 1980 to June 1990. in the Deparment of Oral and Maxillofacial surgery, Yonsei Dental hospital. This study contained the clinicostatiscal analysis of the frequency in relation to sex, age, location, chief complaints, duration, radiographic findings, histopathilogic findings and treatment methods. the result of this study were as foollows : 1. Benign odontogenic tumors of 56 cases disclosed 43 cases(76%) of ameloblastomas(28 cases, 50%), odontomas(15 cases, 26%), and other 6 types lesions(13 cases, 24%). 2. Benign odontogenic tumors occured mainly in the first and second decades(61%), male to female ratio oof the study being 1m5:1. Also the majority of cases occured in the mandible than in the maxilla(3:1). 3. In ameloblastoma 1) total 28 cases(50 %) of ameloblastoma occured in the average age of 35.8 years and had a 3:1 male predominance, mainly in the first, second and third decades(19 cases, 68%). The majority of the cases occured in the mandible, especially 14 cases(50%) in the body ramus-angle and body-angle-r4amus-coronoid process. The most common complaint was the swelling without pain(13 cases, 46). As regards duration, 16 cases(57%) was less than 1 year. 2) Radiographically, the unilocular(15 cases, 54%) annd multilocular lesions(13 cases, 46%) were similar distribution, 18 cases(64%) showed the apparent root resorption. 3) histologically, plexiform type was predominantly(10 cases), most of plexiform type was found in the young ages, radiographically it was unilocular type. 4) Radical resection was performed in 12 cases(58%). 6 cases recurredc after surgery and matastasis was absent. 4. In odontoma 1) Total 15 case(26%) of odontoma occured in the less than 30 years of age, the average age was 15.3 years, and sex distribution was not remarkable. The incidence was similar between maxilla and mandible, but more common in the premaxilla, posterior mandible. The most common chief complaint was the delayed eruption of tooth(5 cases, 33%) and followed by the routine radiographic examination(4 cases, 27%). The 8 cases(53%) were of complex type and 7 cases(47%) were of compound type. 5. 6 types of other benign odontogenic tumor, occured in the first and second decades(10 cases, 77%) and shwed similar sexual distribution. Also the incidence was similar beteen maxilla and mandible, but AOT was presented only in the maxilla and odontogenic myxima in the mandible.
리빙랩과 린 스타트업을 활용한 스타트업 지원 비즈니스 모델에 관한 연구
정성훈(Chung, Sung Hoon),김은희(Kim, Eun Hee),김세진(Kim, Se Jin) 한국창업학회 2017 한국창업학회지 Vol.12 No.1
Recently the importance of start-up increases and a government policy for supporting start-up is actively being made. However, the success rate of start-up is not very high. The purpose of this study is to suggest a start-up support business model to increase the success rate of start-up. In this research, failure factors of start-up business was analyzed based on literature reviews, and several cases of start-up support business model were studied. Finally we developed a web-based business model for start-up support was developed applying ‘Living lab’ platform and ‘Lean start-up’ process, and analyzed differences between previous models and the new model.