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      • 식물혈구응집소 Sanguisorba Officinolis. L.가 실혈가토의 조혈기능에 미치는 영향

        정성화,백승룡 최신의학사 1975 最新醫學 Vol.18 No.1

        Sanguisorba Officinolis L (S. 0. L.) has been known to possess phytohemagglutin activity. This experimental study is undertaken to evaluate whether S. 0. L. has effect on hematopoietic activity in rabbit. Each rabbit of experimental group was injected 1.0ml of S.O. L. extract intravenously just after bleeding, and studied peripheral blood in R.B.C. count, hematocrit count, hemoglobin, reticulocyte count, total W. B. C. count, lymphocyte and granulocyte count. The result obtained are as follow: 1. Interval of recovery in erythrocytic series was shortened by S.O. L. injection after bleeding. 2. Higher level of peripheral leukocyte count in early stage was noted by S.O.L. injection after bleeding. 3. Higher level of peripheral leukocyte count was due to increased lymphocyte count. S. 0. L. seems to possess activities to stimulate the bone marrow hematopoiesis and the lymphopoiesis.

      • 표면처리가 장석도재의 굴곡강도에 미치는 영향

        정성화,임범순,김철위 서울대학교 치과대학 치과생체재료학교실 1995 치과생체재료학 논문집 Vol.3 No.1

        Dental ceramics exhibits excellent esthetic, compressive strength and chemical durability, good tissue compatibility and transulcency comparable to natural teeth. Dental ceramics, however, have brittleness as ell as low tensile and shear strength and are extremely sensitive to brittle fracture initiated at surface defects. Glazing and polishing treatments can reduce the influence surface flaws, which lead to an increase in strength of the porcelain. And the other method of strengthening the porcelain is to generate a state of residual compression in the surface, which can be accomplished either by ion exchange treatment or thermal tempering. The object of this study was to compare the effect of various surface treatments on the flexural strength of feldspathic porcelain. Bars of feldspathic porcelain specimen (3×3×30㎜) were prepared from Vintage (Shofu) body procelain by condensing slurries into a platinum foil mould , then sintered in a furnace (Master Splint 120) according to the manufacturer's recommendations under vacuum. The bars were divided into the seven groups : self-glazing (control), over glazing subsequent to ion exchange, and ion exchange subsequent to over-galzing. The ion exchange treatment consisted of applying Ceramicoat past (GC) as evenly as possible to the porcelain using a paintbursh. The coating material was dried for 20 minutes at 150℃, followed by firing at 450℃ for 30 minutes. To evaluate the effect of ion exchange temperature, the same drying cycle was followed by 30-minute heat treatments at 350℃, 400℃, 500℃, and 550℃. Each specimen was loaded to failure on a universal testing machine with a crosshead speed of 0.02 ㎝/min. 7∼10 specimens in each groups were test and the mean value for flexural strength was calculated. The fracture surfaces were examined by a scanning electron microscope. For qualitative analysis of the relative changes in potassium and sodium concentrations after ion exchange treatment, energy dispersive x-ray analysis was performed on the surface and bulk section of the fractured surface. Quatitative chemical analyses were performed on the cross section of the specimen after ion exchange treatment by a scanning elecron microscope equipped with a wavelength dispersive x-ray analyzer. Analyses were made in 10∼20 ㎛ below the treated surface. From the experiment, the following results were obtained: 1. The flexural strength was increased by 37% using over-laze treatment, but polishing or heat treatments of feldspathic did not show significant difference (p>0.05) relative to the self-glaze control group. 2. Relative to the control group (self-glaze), the mean flexural strengths of specimen were increased by ion exchanged treatment : 20% at 350℃, 28% at 400℃, and 56% at 450℃ and 500℃. 3. The effect of ion exchange treatment was lost if the porcelain was subsequently treated by self-glaze. The group with ion exchange treatment subsequent to over-glaze treatment showed the highest flexural strength among the experimental groups. 4. The fracture surface of the specimen with ion exchange treatment showed the hackle region, which could imply the degree of fracture resistance in the ion exchanged layer. 5. The chemical analysis (EDX and WDX) results showed that the effect of ion exchange was extended to 50 ㎛ below the ion treated surface.

      • KCI등재

        충수돌기에서 발생한 신경초종: 증례 보고

        정성화,박원규,김재운,장재천,장한원,정영진,배영경,은종렬 대한영상의학회 2006 대한영상의학회지 Vol.54 No.2

        Schwannoma is a benign neurogenic tumor arising from the nerve sheath, and it presents as a well defined mass. Isolated gastrointestinal schwannoma is a relatively rare finding and schwannoma of the appendix is extremely rare. We report here on a case of schwannoma that arose from the appendix, and this lesion was pathologically confirmed. 신경초종은 신경초에서 발생하는 신경원성 종양이며 대개 경계가 좋고 양성인 경우가 많다. 위장관계에서 드물게 발생하며 충수돌기에서 발생한 신경초종은 매우 드물다. 충수돌기에서 생긴 신경초종으로 수술 후 병리 조직학적으로 확진된 증례를 경험하였기에 이를 보고한다.

      • KCI등재

        췌장 질환 진단에서 18G 절단침을 이용한 초음파 유도하 심부침생검의 임상적 유용성

        정성화,박원규,장재천,김재운,조재호,장한원,이재교,최준혁 대한영상의학회 2008 대한영상의학회지 Vol.58 No.1

        목적 : 췌장 질환을 의심하는 환자에서 18G 절단침을 사용한 초음파 유도 하 췌장 심부침생검의 진단 성적과 합병증을 분석하여 그 유용성과 안전성에 대해서 알아보고자 하였다. 대상과 방법 : 2001년 5월부터 2005년 10월까지 18G 절단침이 달린 고속 생검총을 이용한 초음파 유도 하 심부침생검으로 췌장 조직검사를 시행한 35명의 환자를 대상으로 진단 성적(조직획득률과 진단정확도)과 합병증 발병률을 분석하였다. 결과 : 35명에서 36회 수의 초음파 유도 하 심부침생검이 시행되었다. 최종 진단은 두 명(장액성 낭성선종과 자가 면역성 췌장염)을 제외한 모든 환자에서 다양한 아형을 가지는 췌장암으로 확인되었다. 진단성적으로 조직 획득률은 97%(35/36)이었고, 진단정확도는 94%(34/36)였다. 악성 종양으로 진단된 경우는 33명이었고, 시술과 관련한 합병증으로 1예(3%)에서만 후기 합병증인 암의 침로 이식이 확인되었다. 결론 : 위의 결과에 의하면 초음파 유도 하 심부침생검은 췌장 병변의 진단에서 유용하며 안전한 방법이다. 특히 이 방법은 췌장암의 아형까지 정확한 조직학적 진단이 가능하다.

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