자유권을 논함

정석근 단국대학교 법학연구소 1959 법학논총 Vol.2 No.1

국내산 초유의 가공방법에 따른 품질특성 연구

정석근,함준상,김동훈,안종남,채현석,유영모,장애라,권일경,이승규,Jeong, Seok-Geun,Ham, Jun-Sang,Kim, Dong-Hun,Ahn, Chong-Nam,Chae, Hyun-Seok,You, Young-Mo,Jang, Ae-Ra,Kwon, Il-Kyung,Lee, Seung-Gyu 한국축산식품학회 2009 한국축산식품학회지 Vol.29 No.4

The characteristics of Holstein colostrum according to the methods that were employed in processing it were analyzed in this study to improve its industrial utilization. Colostrum samples were collected from the dairy farm of the National Institute of Animal Science (NIAS). The milk fat, protein, lactose, and SNF contents of colostrum were 4.34, 6.99, 3.37, and 11.10%, respectively. The effects of spray drying, freeze drying, freezing, acidification, and inoculation of lactic-acid bacteria on the characteristics of colostrum were then compared. The freezing of colostrum was found to be proper for long-term storage in a farm. Freeze-dried colostrum powder could not meet the processing requirements and the component standards for animal products in terms of the total bacterial and coliform bacteria counts, but spray-dried colostrum powder could meet the microbiological requirements because of its bactericidal effect during the spray-dry treatment. The inoculation of lactic-acid bacteria showed a better inhibitory effect on coliform than the acidification treatment, but protein precipitation appeared because of the low pH and the high acidity. To estimate the effects of the processing methods employed on the IgG of colostrum, the IgG contents of the milk treated by long temperature long time (LTLT) ($65^{\circ}C$, 30 min), by inoculating the lactic acid bacteria starter, by spray drying, and by freeze drying were measured. The IgG contents of the colostrum were changed significantly by the processing treatment employed, from 53.98 mg/mLto 33.28, 34.82, 21.98, and 36.89 mg/mL, respectively.

만성전립선염/만성골반통증후군과 비뇨생식기 마이코플라즈마 및 클라미디아 감염과의 관계

정석근,이상돈 대한요로생식기감염학회 2011 Urogenital Tract Infection Vol.6 No.1

Purpose: Chronic prostatitis frequently occurs in men of all ages. Recent studies suggest that fastidious microorganisms may play a role in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The aim of this study was to investigate if correlation exists between genitourinary Mycoplasmas and Chlamydia infections and CP/CPPS. Materials and Methods: We evaluated Mycoplasmas and Chlamydia prostatitis in 222 patients diagnosed with CP/CPPS from November 2008 to January 2011 by using the Chlamydia and Mycoplasma IST2 kits. Results: Of the 222 patients, 33 (14.9%) and 189 (85.1%) were respectively classified category IIIa (inflammatory CP/CPPS) and IIIb (non-inflammatory CP/CPPS). On kit tests, 10 (30.3%) of the 33 category IIIa and 55 (29.1%) of the 189 category IIIb cases were positive for causative microorganism. Conclusions: The results suggest close correlation between genitourinary Mycoplasmas and Chlamydia infections and CP/CPPS. In addition, the Chlamydia and Mycoplasma IST2 kits may be useful for simple detection of fastidious microorganisms in CP/CPPS.

포경상태 소아들에서 국소 스테로이드 제제(0.05% Clobetasol Propionate)의 효능

정석근,방성익,이상돈 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.12

Purpose: We evaluated the effect of a topical steroid(0.05% clobetasol propionate[DermovateⓇ]) on phimosis. Materials and Methods: Between May 2005 and May 2007, 30 boys with phimosis were assigned to receive topical application of Dermovateⓡ. Of the 30 boys, 19 boys had concealed penises. The parents of the boys were instructed to retract the foreskin gently without causing pain, and to apply the topical steroid over the stenotic opening of the prepuce twice daily for 4 weeks then for another 4 weeks if no improvement was achieved. Retractibility of the prepuce was graded from 1-6. Response to treatment was arbitrarily defined as improvement in the retractibility score(complete response, score 5 and 6; partial response, score 3 and 4; no response, score 1 and 2). The effect of treatment was studied with respect to the duration of treatment, age, and an associated concealed penis. Results: The pretreatment grade in all patients was a retractibility score of 1. The mean age of the patients was 48.5±27.6 months(range, 7-108 months). The complete response rates in boys treated for 4 and 8 weeks were 50% and 73.3%, respectively. In boys younger than 3 years of age (n=12) and older than 3 years of age(n=18), the complete response rates were 75% and 72.2%, respectively(p=0.866). In boys with or without an associated concealed penis(n=19 and n=11, respectively), the complete response rates were 63.1% and 90.9%, respectively(p=0.199). No adverse effect was encountered in all patients. Conclusions: Our data suggest that the application of topical steroids for 8 weeks as a first line treatment of phimosis may be effective, although further studies are needed to establish the definite efficacy and safety of this procedure. Purpose: We evaluated the effect of a topical steroid(0.05% clobetasol propionate[DermovateⓇ]) on phimosis. Materials and Methods: Between May 2005 and May 2007, 30 boys with phimosis were assigned to receive topical application of Dermovateⓡ. Of the 30 boys, 19 boys had concealed penises. The parents of the boys were instructed to retract the foreskin gently without causing pain, and to apply the topical steroid over the stenotic opening of the prepuce twice daily for 4 weeks then for another 4 weeks if no improvement was achieved. Retractibility of the prepuce was graded from 1-6. Response to treatment was arbitrarily defined as improvement in the retractibility score(complete response, score 5 and 6; partial response, score 3 and 4; no response, score 1 and 2). The effect of treatment was studied with respect to the duration of treatment, age, and an associated concealed penis. Results: The pretreatment grade in all patients was a retractibility score of 1. The mean age of the patients was 48.5±27.6 months(range, 7-108 months). The complete response rates in boys treated for 4 and 8 weeks were 50% and 73.3%, respectively. In boys younger than 3 years of age (n=12) and older than 3 years of age(n=18), the complete response rates were 75% and 72.2%, respectively(p=0.866). In boys with or without an associated concealed penis(n=19 and n=11, respectively), the complete response rates were 63.1% and 90.9%, respectively(p=0.199). No adverse effect was encountered in all patients. Conclusions: Our data suggest that the application of topical steroids for 8 weeks as a first line treatment of phimosis may be effective, although further studies are needed to establish the definite efficacy and safety of this procedure.

The Relationship between B7-H4 Expression and Clinicopathological Characteristics in Clinical Stage T1 Conventional Renal Cell Carcinoma

정석근,최경운,이상돈,이정주,정문기 대한비뇨의학회 2011 Investigative and Clinical Urology Vol.52 No.2

Purpose: The diagnosis of clinically early-stage (T1) renal cell carcinoma (RCC) has increased. The present study evaluated the association of B7-H4 expression on the pathological outcome and recurrence of carcinoma in the T1 stage of RCC. Materials and Methods: Among patients who underwent partial or radical nephrectomy after diagnosis of T1 stage RCC during the period of January 2000 to March 2007, 102 pathologically confirmed cases of clear cell carcinoma were included in this study. The patients' medical records were reviewed retrospectively. For the immunohistochemical staining tests, the B7-H4 antibody (Abbiotec 1:500) was used, and clinicopathological characteristics were analyzed. Results: The mean age of the patients (39 males: 38.2%, 63 females: 61.8%) was 53.0± 12.0 years (range, 31-74 years), and the mean follow-up time was 33.4±21.0 months (range, 6-84 months). B7-H4 expression was positive in 18 cases and negative in 84 cases. Recurrence during the follow-up period occurred in 5 cases in the group with positive B7-H4 expression and in 7 cases in the group with negative B7-H4 expression, respectively (p=0.035). In the univariate analysis, a statistically significant relationship was observed only for the presence of B7-H4 expression (p=0.0019). In the multivariate analysis, other than the expression of B7-H4, cancer size and TNM stage had effects on the recurrence of cancer. Conclusions: For clear cell RCC, B7-H4 expression had a critical impact on the prognosis of the patients, particularly on the recurrence of the carcinoma in patients with clinical stage T1 RCC.

영아에서의 열성 요로감염: 일차성과 재발성 감염의 비교분석

정석근,이상돈,공도훈 대한요로생식기감염학회 2011 Urogenital Tract Infection Vol.6 No.2

Purpose: Febrile urinary tract infection (UTI) is common in infants and is associated with the risk for renal scarring and long-term complications. We retrospectively investigated the risk factors for recurrent UTI in infants with febrile UTI. Materials and Methods: We identified 108 infants (mean age 4.5±{3.2 months; range 1-12 months) with febrile UTI who visited the emergency room from January, 2007 to December, 2010. We retrospectively reviewed sex, age, urine analysis, pathogen, leukocytosis, C-reactive protein (CRP), hydronephrosis, hydronephrosis grade and severity, vesicoureteral reflux (VUR), VUR grade and severity. We performed comparative studies of infants with recurrent UTI (group A; n=20, 18.5%) and primary UTI (group B; n=88, 81.5%). High-grade hydronephrosis and high-grade VUR were both defined as grade 3 or higher. Results: In 108 infants with febrile UTI, the male to female ratio was 3.2:1 (82 boys, 26 girls). On cross analysis of group A and B, there was no significant difference according to sex, age, CRP level in serum, leukocytosis and inflammation markers in urine analysis (p>0.05). Comorbidity of hydronephrosis and VUR was 52.8% (n=57) and 13.9% (n=15), respectively. Group A had more high grade hydroneprhosis, high grade reflux, bilateral reflux and a non-Escherichia coli strain in the urine culture compared with group B (p<0.05).The presence and laterality of hydronephrosis was not significantly different (p>0.05). Conclusions: During the first year after birth, high grade VUR, bilateral VUR, and a non-E. coli strain in the urine culture significantly increases the risk of recurrent UTI. Therefore, in infants with febrile UTI, imaging studies and urine culture are important for evaluation of recurrence probability.

초음파 처리가 원유의 이화학적 미생물학적 품질에 미치는 영향

정석근,인영민,박범영,유영모,김진형,조수현,이종문,김용곤 한국축산식품학회 1999 한국축산식품학회지 Vol.19 No.4

간행사

정석근 단국대학교 법학연구소 1959 법학논총 Vol.2 No.1

N/A

고환에 발생한 경계영역성 장액성 유두상 낭선종

정석근,박현준,박성우,천원희,박남철 대한남성과학회 2007 The World Journal of Men's Health Vol.25 No.1

Asynchronous Responses of Fish Assemblages to Climate-driven Ocean Regime Shifts between the Upper and Deep Layer in the Ulleung Basin of the East Sea from 1986 to 2010

정석근 한국해양과학기술원 2014 Ocean science journal Vol.49 No.1

Past studies suggested that a basin-wide regime shift occurred in 1988-1989, impacting marine ecosystem and fish assemblages in the western North Pacific. However, the detailed mechanisms involved in this phenomenon are still yet unclear. In the Ulleung basin of the East Sea, filefish, anchovy and sardine dominated the commercial fish catches in 1986-1992, but thereafter common squid comprised > 60% of the total catch in 1993-2010. To illuminate the mechanisms causing this dramatic shift in dominant fisheries species, I related changes in depth-specific oceanographic conditions from 0 to 500 m to inter-annual changes in the fish assemblage structure from 1986 to 2010. In the upper layer of 50-100 m depths, water temperature suddenly increased in1987-1989, and consequently warm-water epi-pelagic species (anchovy, chub mackerel, and common squid) became dominant, while sardine, relatively cold-water epi-pelagic species, nearly disappeared. An annual index of the volume transport by the Korea Strait Bottom Cold Water, originating from the deep water of the Ulleung Basin, displayed a sudden intensification in 1992-1993, accompanied by decreased water temperature and increased water density in the deep water and replacement of dominant benthopelagic species from filefish, warm-water species, to herring and cod, cold-water species. The results suggest that climate-driven oceanic changes and the subsequent ecological impacts can occur asynchronously, often with time lags of several years, between the upper and the deep layer, and between epi-pelagic and deepwaterfish assemblages.