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폴리에틸렌 테레프탈레이트 이소프탈레이트 멀티필라멘트의 열수축과 열수축 응력에 관한 연구
조광신,정상용 한국섬유공학회 1997 한국섬유공학회지 Vol.34 No.7
The thermal shrinkage and its stress of poly(ethylene terephthalate-isophthalate) copolyester multifilament were investigated in terms of crystallinity and molecular orientation. Central composite design was used to determine the number of experiments. The thermal shrinkage increased with isophthalic acid content and this phenomenon was explained in terms of crystallinity. The thermal shrinkage decreased but peak shrinkage stress increased with the increase of draw ratio. This phenomenon was related to the strain-induced crystallization. Both the thermal shrinkage and peak shrinkage stress decreased with the increase of drawing temperature and this phenomenon was due to the molecular orientation of the copolyester.
하기태,김영미,정상신,김준기,최달영 대한동의생리학회,대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.1
The textual comments on Shanghanlun and Jinguiyaolue were found in Hyangyakjipsung-bang, the representative medical book in the early period of Choson Dynasty. In all 57 chapters of the book, 17 chapters are related to those comments, and only one comment is quoted from all chapters except the chapter of "Shanghaniun" and "Jinguiyaolue". As classified the comments by citation order, Jinguifang had 14 comments, Zhangzhongjing had 7 comments, Zhangzhongjing had 4 omments, and Jinguiyuhan had 1 comment. Comparing to the present version, 16 comments were qouted from Jinguiyaolue and 7 comments were quoted from hanghanlun and 1 comment was quoted from Jinguiyuhanjing, but the source of 2 comments were not identified. Especially the 1 comment from Jinguiyuhanjing not only shows the importing date of the book into Korea, but also proofs the importance of the book which can refute the supposed source of the book as a reprint by Chenshijie in China. This results showed that Zhangzhongjing's books, which has imported before the early period of Chosun Dynasty, had an influence on Korean Medicine. As a result, further research on the medical books in the early period of Chosun Dynasty excepting Hyangyakjipsung-bang will be necessary.
CCl_4로 誘發된 白鼠의 肝損傷에 대한 葛根의 肝保護作用 연구
현동환,정선영,정상신,하기태,김철호,김동욱,김준기,최달영 대한동의생리학회,대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.2
In the present study, we investigated the protective effect of the Puerarie Radix water extract (PRE) against CCI_4-induced hepatotoxicity and the mechanism underlying these protective effects in the rats. The pretreatment of PRE has shown to possess a significant protective effect by lowering the serum alanine and aspartate aminoteansferase (AST and ALT) and alkaline phosphatase (ALP). This hepatoprotective action was confirmed by histological observation. In addition, the pretreatment of PRE prevented the elevation of hepatic malondialdehyde (MDA) formation and the depletion of reduced glutathione (GSH) content and catalase activity in the liver of CCI_4-injected rats. The PRE also displayed hydroxide radical scavenging activity in a dose-dependent manner (IC50 = 83.6 ㎍/ml), as assayed by electron spin resonance (ESR) spin-trapping technique. Moreover, the expression of cytochrome P450 2E1 (CYP2E1) mRNA, as measured by reverse transcriptase-polymerase chain reaction (RT-PCR), was significantly decreased in the liver of PRE-pretreated rats when compared with that in the liver of control group. Based on these results, it was suggested that the hepatoprotective effects of the PRE may be related to anfioxidant effects and regulation of CYP2E1 gene expression
$CC1_4$로 유발된 백서의 간손상에 대한 갈근의 간보호작용 연구
현동환,정선영,정상신,하기태,김철호,김동욱,김준기,최달영,Hyun Dong Hwan,Jung Sun Yeong,Jung Sang Shin,Ha Ki Tae,Kim Cheorl Ho,Kim Dong Wook,Kim June Ki,Choi Dall Yeong 대한동의생리학회 2003 동의생리병리학회지 Vol.17 No.2
In the present study, we investigated the protective effect of the Puerarie Radix water extract (PRE) against CCl₄-induced hepatotoxicity and the mechanism underlying these protective effects in the rats. The pretreatment of PRE has shown to possess a significant protective effect by lowering the serum alanine and aspartate aminoteansferase (AST and ALT) and alkaline phosphatase (ALP). This hepatoprotective action was confirmed by histological observation. In addition, the pretreatment of PRE prevented the elevation of hepatic malondialdehyde (MDA) formation and the depletion of reduced glutathione (GSH) content and catalase activity in the liver of CC1₄-injected rats. The PRE also displayed hydroxide radical scavenging activity in a dose-dependent manner (IC50 = 83.6 μg/ml), as assayed by electron spin resonance (ESR) spin-trapping technique. Moreover, the expression of cytochrome P450 2E1 (CYP2E1) mRNA, as measured by reverse transcriptase-polymerase chain reaction (RT-PCR), was significantly decreased in the liver of PRE-pretreated rats when compared with that in the liver of control group. Based on these results, it was suggested that the hepatoprotective effects of the PRE may be related to antioxidant effects and regulation of CYP2E1 gene expression.