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        Percutaneous Treatment of an Injured Coronary Stent Using the Looping Wire Technique

        정래영,이상록 전남대학교 의과학연구소 2013 전남의대학술지 Vol.49 No.3

        Drug-eluting stent implantation is an effective treatment for coronary artery disease,yet unexpected serious complications during stent implantation are possible. A 70-year-old man with unstable angina presented with a left main bifurcation lesion. Two drug-eluting stents were successfully deployed at the left main bifurcation lesion by the mini-crush technique under intravascular ultrasound guidance. However, after removal of the wire and intravascular ultrasound catheter, the stent of the proximal left circumflex artery was damaged and shortened at the distal edge. We used a looping wire technique to cross the injured stent and we successfully re-dilated the damaged portion of the stent. Finally, we deployed an additional drug-eluting stent at the left circumflex artery over the damaged stent. Our case illustrates the importance of gentle handling of devices during coronary intervention. Furthermore, interventionists should keep in mind the role of intravascular ultrasound when treating this kind of serious complication.

      • KCI등재

        실시간 하이브리드 실험 시스템을 위한 Implicit 시간적분법

        정래영 한국지진공학회 2006 한국지진공학회논문집 Vol.10 No.5

        이 논문에서 소개되는 실시간 하이브리드 실험 시스템은 유사동적실험법을 근거로 하고 있으며, 실제 실험과수학적 모델을 이용한 수치해석을 결합한 실험법이다. 이 시스템은 종래의 유사동적해석법에 비해 지진하중을 받는 구조물의 실시간 반응에 근접하는 현저히 높은 하중재하 속도를 고려할 수 있도록 설계되었다. 또한 다자유도 구조물에 대해 안정적인 해석환경을 제공하기 위해 이 시스템은 implicit 시간적분법을 이용하여 수치해석을 수행한다. 이 논문은 연구를 통해 개발된 시스템의 전반적인 개요와 구성요소 그리고 이 시스템에서 사용하는 수치 해석법의 성능을 평가하기 위해 수행된 수치해석을 소개한다. 연구 결과 개발된 시스템에 적용된 수치해석법은 성능이 매우 우수하다는 것이 증명되었다. The Real-Time Hybrid Test system presented in this paper is based on the pseudodynamic test method, and it combines physical testing with model-based simulation. The system is designed to achieve a rate of loading that is significantly higher than that of a conventional pseudodynamic test approaching the real-time response of a structure subjected to earthquake loads. To provide robust computation environment for the analysis of many degree-of-freedom structures, the system adopts an implicit time integration scheme in the model-based simulation. This paper presents an overview of the developed system and numerical simulations that were conducted to evaluate the performance of the computation scheme adopted here. Results of these studies have demonstrated the good performance of the computation scheme for real-time multiple-degree-of-freedom tests.

      • KCI등재

        개구 저감률에 의한 원전 SC벽체의 내력 평가

        정철헌,정래영,문일환,이정휘,Chung, Chul-Hun,Jung, Raeyoung,Moon, Il Hwan,Lee, Jungwhee 대한토목학회 2013 대한토목학회논문집 Vol.33 No.6

        지금까지 수행된 개구부가 존재하는 벽체에 대한 연구는 대부분 RC 벽체에 대해서 수행되었으며, SC(Steel plate Concrete) 벽체에 설치되는 개구부에 대한 연구는 수행된 예가 적다. 최근에 국내에서 개발된 SC 벽체는 원전구조물에 일부 적용되고 있지만, 관련 설계기준인 KEPIC-SNG에서도 개구부를 갖는 SC 벽체에 대한 설계법은 명확하게 정의되지 않았다. 본 연구에서는 원전구조물내 벽체에 설치되는 SC 벽체를 대상으로 개구 저감률이 구조내력에 미치는 영향을 평가하였다. 개구 저감률을 고려한 구조내력 평가 결과는 실험 및 수치해석 결과와 비교분석하였다. The shear wall with openings built with reinforced concrete(RC) have been elaborately studied by many researchers, whereas the steel plate concrete(SC) wall structure has not been investigated as much. Recent SC wall structures developed in Korea have been partly applied to nuclear power plant structures, although its design specification or guideline for the SC wall structure with openings has not been completed yet. This study based on the account for the area lost to openings evaluates the effects of opening on the structural capacity of the SC structure within nuclear power plant. The results obtained from the study on the area lost to openings have been compared with experimental and numerical studies.

      • KCI등재

        Rosuvastatin Reduces Blood Viscosity in Patients with Acute Coronary Syndrome

        이상록,정래영,정진무,김이식,이선화,이경석,채제건,이동환,김달식,김원호,고재기 대한심장학회 2016 Korean Circulation Journal Vol.46 No.2

        Background and Objectives Wall shear stress contributes to atherosclerosis progression and plaque rupture. There are limited studies for statin as a major contributing factor on whole blood viscosity (WBV) in patients with acute coronary syndrome (ACS). This study investigates the effect of statin on WBV in ACS patients. Subjects and Methods We prospectively enrolled 189 consecutive patients (mean age, 61.3±10.9 years; 132 males; ST-segment elevation myocardial infarction, n=52; non-ST-segment elevation myocardial infarction, n=84; unstable angina n=53). Patients were divided into two groups (group I: previous use of statins for at least 3 months, n=51; group II: statin-naïve patients, n=138). Blood viscosities at shear rates of 1 s-1 (diastolic blood viscosity; DBV) and 300 s-1 (systolic blood viscosity; SBV) were measured at baseline and one month after statin treatment. Rosuvastatin was administered to patients after enrollment (mean daily dose, 16.2±4.9 mg). Results Baseline WBV was significantly higher in group II ([SBV: group I vs group II, 40.8±5.9 mP vs. 44.2±7.4 mP, p=0.003], [DBV: 262.2±67.8 mP vs. 296.9±76.0 mP, p=0.002]). WBV in group II was significantly lower one month after statin treatment ([SBV: 42.0±4.7 mP, p=0.012, DBV: 281.4±52.6 mP, p=0.044]). However, low-density lipoprotein cholesterol level was not associated with WBV in both baseline (SBV: R2=0.074, p=0.326; DBV: R2=0.073, p=0.337) and after one month follow up (SBV: R2=0.104, p=0.265; DBV: R2=0.112, p=0.232). Conclusion Previous statin medication is an important determinant in lowering WBV in patients with ACS. However, one month of rosuvastatin decreased WBV in statin-naïve ACS patients. Background and Objectives Wall shear stress contributes to atherosclerosis progression and plaque rupture. There are limited studies for statin as a major contributing factor on whole blood viscosity (WBV) in patients with acute coronary syndrome (ACS). This study investigates the effect of statin on WBV in ACS patients. Subjects and Methods We prospectively enrolled 189 consecutive patients (mean age, 61.3±10.9 years; 132 males; ST-segment elevation myocardial infarction, n=52; non-ST-segment elevation myocardial infarction, n=84; unstable angina n=53). Patients were divided into two groups (group I: previous use of statins for at least 3 months, n=51; group II: statin-naïve patients, n=138). Blood viscosities at shear rates of 1 s-1 (diastolic blood viscosity; DBV) and 300 s-1 (systolic blood viscosity; SBV) were measured at baseline and one month after statin treatment. Rosuvastatin was administered to patients after enrollment (mean daily dose, 16.2±4.9 mg). Results Baseline WBV was significantly higher in group II ([SBV: group I vs group II, 40.8±5.9 mP vs. 44.2±7.4 mP, p=0.003], [DBV: 262.2±67.8 mP vs. 296.9±76.0 mP, p=0.002]). WBV in group II was significantly lower one month after statin treatment ([SBV: 42.0±4.7 mP, p=0.012, DBV: 281.4±52.6 mP, p=0.044]). However, low-density lipoprotein cholesterol level was not associated with WBV in both baseline (SBV: R2=0.074, p=0.326; DBV: R2=0.073, p=0.337) and after one month follow up (SBV: R2=0.104, p=0.265; DBV: R2=0.112, p=0.232). Conclusion Previous statin medication is an important determinant in lowering WBV in patients with ACS. However, one month of rosuvastatin decreased WBV in statin-naïve ACS patients.

      • KCI등재

        비부착텐던 PSC 격납건물에 대한 구조건전성시험 및 수치해석 II

        노상훈,정래영,이병수,임상준,Noh, Sanghoon,Jung, Raeyoung,Lee, Byungsoo,Lim, Sang-Jun 한국전산구조공학회 2015 한국전산구조공학회논문집 Vol.28 No.5

        원자로 격납건물은 냉각재상실사고와 같이 내부의 과도한 압력이 유발되는 사고에 있어서도 방사성 물질이 외부로 누출되지 않도록 막는 최종의 방벽이다. 이러한 격납건물의 기능적 중요성에 기인하여, 건설 초기 구조건전성시험(SIT)을 수행한다. 이러한 SIT거동을 가장 실제와 가깝게 예측하기 위한 해석 연구를 수행하였다. 해당 연구의 결과는 2편의 논문으로 정리되었는데, 본 논문은 그 중 II편으로 I편의 해석모델 구성 시의 주요 고려사항의 분석 및 예비해석 결과를 반영한 상세 해석 모델의 구성 과정 및 해석 결과를 제시하고 있다. 특히 비부착식 텐던으로 시공된 구조물에서 덕트관에 의한 강성 저감효과 및 덕트관을 사이에 둔 텐던과 콘크리트간의 밀착 여부에 따른 영향을 해석 시 최대한 고려하고자 하였다. 이러한 과정을 통해 구축된 해석 모델에 따른 변위과 신고리 3호기 SIT 측정변위를 비교한 결과, ASME CC-6000 기준을 충분히 만족시키는 결과가 나타남을 확인하였다. A reactor containment acts as a final barrier to prevent leakage of radioactive material due to the possible reactor accidents into external environment. Because of the functional importance of the containment building, the SIT(Structural Integrity Test) for containments shall be performed to evaluate the structural acceptability and demonstrate the quality of construction. In this paper, numerical analyses are presented, which simulate the results obtained from the SIT for a prestressed concrete(PSC) structure. A sophisticate structural analysis model is developed to simulate the structural behavior during the SIT properly based on various preliminary analysis results considering contact condition among structural elements. From the comparison of the analysis and test results based on the acceptance criteria of ASME CC-6000, it can be concluded that the construction quality of the containment has been well maintained and the acceptable performance of new design features has been verified.

      • KCI등재

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