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      • 유비쿼터스 환경에서의 정보보조 시스템의 설계와 구현

        전홍준(hong-jun Chun),이상훈(Sang-hoon Lee),서일홍(Il Hong Suh) 대한전기학회 2004 대한전기학회 학술대회 논문집 Vol.2004 No.7

      • 非抑制性癎疾 特히 精神運動發作에 對한 Clonazepam(RO5-4023)의 治療經驗

        全洪俊,嚴龍燮 順天鄕大學校 1980 의대논문집 Vol.5 No.-

        Clonazepam was administered via p. o. and i. v. routes to patients with uncontrolable epilepsy mainly consisting of psychomotor seizure. The following results were obtained : 1) Clonazepam of 3∼5 ㎎/day was administered via p. o. route to 38 patients with other antiepileptic drugs. The effcctive rate was 73.6%. The average effuctive dose was 3.5 ㎎/day. The drug was remarkably effective in patients with psychomotor seizure. Of 14 patients with psychomotor seizure, 7 patients (50%) responded exellently and 4 (29%) responded effectively. The drug was considered to be worth employing in this kind of incurable epilepsy. Furthrmore, as seen in other reports, this drug showed effectiveness in the other spasm types, Particuraly infantile spasm and petitmal varient. 2) In general, administration of more than 3 months fairly lowered the effective rate, but in the most of cases efficient anti-epileptic effects which encouraged continuous administration were seen when administered continuously more than 6 months. 3) Two patients with status epilepticus were administercd 1-2㎎ of clonazepam via i.v. route. In both of them complete inhibition of spasm, clearance of consciousness, and normalizatiop of EEG were seen just after the injection. These effects continued for about 20-25 minutes. In our experience these effects were more remarkable than those when administered diphenylhydantoin and diazepam. 4) when administered orally, many patients complained of drowseness as a side effect, but this could be reduced by changing the dosage of this drug or combination of the other anti-epileptic drugs. Of 40 cases drop out cases because of this side effect were 2 cases. Other side effects were not seen except one case of hypersalivation, and results of clinical laboratory examinations could not find any adverse reactions attributable to this drugs.

      • 非抑制性癎疾 特히 精神運動發作에 對한 Clonazepam(RO5-4023)의 治療經驗

        全洪俊,嚴龍燮 朝鮮大學校 醫學硏究所 1980 The Medical Journal of Chosun University Vol.- No.-

        Clonazepam was administered via p. o. and i. v. routes to patients with uncontrolable epilepsy mainly consisting of psychomotor seizure. The following results were obtained : 1) Clonazepam of 3∼5 mg/day was administered via p.o. route to 38 patients with other antiepileptic drugs. The effective rate was 73.6%. The average effective dose was 3.5mg/day. The drug was remarkably effective in patients with psychomotor seizure. Of 14 patients with psychomotor seizure, 7 patients (50%) responded exellently and 4 (29%) responded effectively. The drug was considered to be worth employing in this kind of incurable epilepsy. Furthmore, as seen in other reports, this drug showed effectiveness in the other spasm types, particuraly infantile spasm and petitmal varient. 2) In general, administration of more than 3 months fairly lowerea the effective rate, but in the most of cases efficient anti-epileptic effects which encouraged continuous administration were seen when administered continuously more than 6 months. 3) Two patients with status epilepticus were administered 1-2mg of clonazepam via i. v. route. In both of them complete inhibition of spasm, clearance of consciousness, and normalization of EEG were seen Just after the injection These effects continued for about 20-25 minutes. In our experience these effects were more remarkable than those when administered diphenylhydantoin and diazepam. 4) when administered orally, many patients complained of drowseness as a side effect, but this could be reduced by changing the dosage of this drug or combination of the other anti-epileptic drugs. Of 40 cases drop out cases because of this side effect were 2 cases. Other side effects were not seen except one case of hypersalivation, and results of clinical laboratory examinations could not find any adverse reactions attributable to this drugs.

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