신장에서 V2-수용체를 통한 옥시토신의 aquaporin-2 발현 조절

전은실,나기영,오윤규,한진석,이정상,주권욱,김진,김근호 대한내과학회 2002 대한내과학회지 Vol.62 No.3

Korean EFL Students’ Learning Motivation in Reading and Listening

전은실 이화여자대학교 교과교육연구소 2010 교과교육학연구 Vol.14 No.1

This study explored various aspects of English reading and listening motivation of Korean university students and how each motivation related to their English reading and listening proficiency respectively. The relationship between English reading motivation and listening motivation was also examined. The participants completed an English reading motivation questionnaire and a listening motivation questionnaire and took a TOEIC style practice test three times during a semester as measurement of their English proficiency. The students’ reading motivation and listening motivation were found to be multidimensional. The prominent factors for English reading motivation were Reading Efficacy, Enjoyment of Reading, Extrinsic Value of Reading, Interests in Reading Materials, and Reading Challenge. The factors identified for English listening motivation were Listening Challenge, Listening Involvement, Interests in Listening Materials, and Extrinsic Value of Listening. Among the reading motivation factors,Reading Efficacy predicted the students’ reading proficiency to a certain degree, and Listening Avoidance predicted the variance of listening proficiency. When the responses to the corresponding items in reading and listening questionnaires were compared, many items were correlated significantly. Based on the results, pedagogical suggestions were presented.

영어 지속적 묵동 활동이 읽기 이해도와 속도에 미치는 영향

전은실 이화여자대학교 교과교육연구소 2015 교과교육학연구 Vol.19 No.4

지속적 묵독(sustained silent reading)은 수업 시간에 일정한 시간을 할애하여 학생들이 꾸준히 자율적으로 읽는 활동으로서 본 연구의 목적은 일반적인 토익 대비 수업에 지속적 묵독 활동을 병행하여 실시할 때 학생들의 읽기 이해도와 속도에 어떤 영향을 주는지 조사하고 또한 학생들이 선택하여 읽은 영어 텍스트에 대하여 흥미도와 난이도 면에서 어떤 반응을 보이는지 알아보고자 하였다. 이를 위하여 대학의 토익 관련 과목 한 학기 동안 한 분반의 학생들은 일반적인 문제풀이, 어휘, 문법 설명 위주의 교수자 중심 수업으로 진행하였고 같은 과목의 다른 분반 학생들은 매주 수업 시간에 15분에서 20분 정도의 시간을 할애하여 지속적 묵독 활동을 병행하였다. 읽기 자료로는 영어 학습용 읽기 교재에서 연구자의 판단에 학생들이 흥미 있게 읽을 수 있는 평균 500단어 정도의 텍스트를 선택하여 활용하였다. 학기 초와 학기 말에 읽기 이해도와 문제풀이 속도, 읽기 속도를 측정한 결과 읽기 이해도와 문제풀이 속도 면에서는 실험반과 통제반 모두 사후에 유의한 향상을 보여주었고 그 향상의 정도는 통제반에 비하여 실험반에서 더 높게 나타났다. 읽기 속도면에서는 지속적 묵독을 시행한 실험반의 경우에는 학기 말에 읽기 속도가 향상을 되었고 일반적인 토익 대비 수업을 한 통제반은 통계적으로 유의한 향상을 보여주지 않았다. 그러나 읽기 속도 향상의 정도가 실험반과 통제반 사이에 유의한 차이는 없었다. 그리고 학생들이 느끼는 텍스트의 흥미도와 난이도 사이에는 어느 정도의 상관관계가 존재하였다. Sustained silent reading (SSR) is usually defined as a students’ silent reading activity conducted in the fixed period of time in class. The main purpose of this study was to investigate the effect of SSR which was applied in TOEIC instruction in the college classroom to see the effect on the students' reading speed and reading comprehension. For one semester, the control group class consisted of traditional TOEIC practices, and the students of the experimental group, besides their regular TOEIC practices, read texts (about 500 words on average) from various English reading materials for 15 to 20 minutes on their own every class for one semester and filled in the activity sheets on which they marked the level of text interest and difficulty. The students' English reading comprehension and reading speed was measured twice, at the beginning and the end of the semester. The data showed that SSR class showed more improvement in terms of reading comprehension than the control class, but not in reading speed. However, the students of the SSR class answered more items in post reading comprehension test than the students of the control class. As for the students' responses to the texts’ interest and difficulty, it seemed that the easier the text was, the more interested the students were. The text difficulty, which was measured by the readability index that calculates text difficulty, was similar compared with the difficulty perceived by the students.

특수도서관의 실태와 개선방안 : 신문사 調査資料室 中心으로

전은실 이화여자대학교 도서관학과 1989 도서관 학보 Vol.- No.7

유육종증에 동반된 막성신염

전은실,김정훈,소영,이상구,조윤숙,김연수,안규리,한진석,김성권,이정상,이현순 대한내과학회 1997 대한내과학회지 Vol.53 No.3S

유육종증에서 사구체신염의 발생은 매우 드물며, 가장 흔히 동반되는 막성신염도 현재까지 20예에 불과하였다. 또한 막성신염의 일부에서 신부전이 동반된 반면 적절한 치료방법은 아직 확립되지 않다. 저자들은 국내에서 유육종증에 동반된 막성신염을 처음으로 경험하였고, 스테로이드 치료후 단백뇨의 관해를 경험하였기에 문헌고찰과 함께 이를 보고하는 바이다. Glomerulonephritis associated with sarcoidosis is very rare and membranous nephropathy is known as the most common form of glomerulonephritis in sarcoidosis. There has been no report of glomerulonephritis associated with sarcoidosis yet in Korea. A 39-year-old woman was admitted to Seoul National University Hospital in July 1993 for pretibial pitting edema and foamy urine. In October 1992, she developed pretibial pitting edema and 1cm sized painless hard skin nodules on left buttock and right breast. At admission, she had nephrotic range proteinuria and right hilar mass. Renal biopsy and mediastinoscopic lymph node biopsy showed membranous nephropathy and noncaseating granulomatous inflammation. Therefore, she diagnosed as membranous nephropathy associated with sarcoidosis and treated with oral prednisolone. Hilar mass was disappeared 1 months after steroid therapy started and proteinuria decreased to nonnephrotic range 4 months later and subsided in March 1996. We report the first case in Korea who was diagnosed as membranous nephropathy associated with sarcoidosis and was responded well to steroid.

The enhanced expression of IL-17-secreting T cells during the early progression of atherosclerosis in ApoE-deficient mice fed on a western-type diet

전은실,최준표,김유선,류성호,김윤근 생화학분자생물학회 2015 Experimental and molecular medicine Vol.47 No.-

Atherosclerosis is a chronic progressive inflammatory disorder and the leading cause of cardiovascular mortality. Here we assessed the dynamic changes of T-cell-derived cytokines, such as inteferon (IFN)-γ, interleukin (IL)-17 and IL-4, during the progression of atherosclerosis in apolipoprotein E-null (ApoE− / −) mice, to understand the role of immune responses in different stages of atherosclerosis. Male ApoE− / − mice were fed a high-fat, western-type diet (WD: 21% lipid, 1.5% cholesterol) after 5 weeks of age and were compared with C57BL/6 wild-type control mice fed a standard chow diet. Atherosclerotic lesions appeared in the aortic sinus of ApoE− / − mice 4 weeks after WD and the lesions progressed and occupied >50% of the total sinus area 16 weeks after WD. Aortic IL-17 mRNA and protein expression started to increase in ApoE− / − mice after 4 weeks on the WD and peaked at around 8–12 weeks on the WD. In terms of systemic expression of T-cell-derived cytokines, IL-17 production from splenocytes after anti-CD3/CD28 stimuli increased from 4 weeks on the WD, peaked at 12 weeks and returned to control levels at 16 weeks. The production of IFN-γ and IL-4 (Th1 and Th2 cytokines, respectively) from splenocytes was delayed compared with IL-17. Taken together, the present data indicate that Th17 cell response may be involved at an early stage in the development of atherosclerosis.

Kidney and Calcium Homeostasis

전은실 전해질고혈압연구회 2008 Electrolytes & Blood Pressure Vol.6 No.2

Plasma calcium concentration is maintained within a narrow range (8.5-10.5 mg/dL) by the coordinated action of PTH, 1,25-(OH)2D3, calcitonin, and ionized calcium (iCa) itself. The kidney plays a key role in this process by the fine regulation of calcium excretion. More than 95% of filtered calcium is reabsorbed along the renal tubules. In the proximal tubules, 60% of filtered calcium is reabsorbed by passive mechanisms. In the thick ascending limb, 15% of calcium is reabsorbed by paracellular diffusion through paracellin-1 (claudin-16). The calcium sensing receptor (CaSR) in the basolateral membrane of the thick ascending limb senses the change in iCa2+ and inhibits calcium reabsorption independent to parathyroid hormone (PTH) and 1,25-(OH)2D3. The fine regulation of calcium excretion occurs in the distal convoluted tubules and connecting tubules despite the fact that only 10-15% of filtered calcium is reabsorbed there. Transient receptor potential vanilloid 5 (TRPV5) and 6 (TRPV6) in the apical membrane act as the main portal of entry, calbindin-D28K delivers Ca2+ in the cytoplasm, and then Na2+/Ca2+ exchanger (NCX1) and plasma membrane Ca2+-ATPase in the basolateral membrane serve as an exit. In the cortical collecting duct, TRPV6 is expressed, but the role might be negligible. In addition to PTH and 1,25-(OH)2D3, acid-base disturbance, diuretics, and estrogen affect on these calcium channels. Recently, klotho and fibroblast growth factor 23(FGF23) are suggested as new players in the calcium metabolism. Klotho is exclusively expressed in the kidney and co-localized with TRPV5, NCX1, and calbindin-D28K. Klotho increases calcium reabsorption through trafficking of TRPV5 to the plasma membrane, and also converts FGF receptor to the specific FGF23 receptor. FGF23:klotho complex bound to FGF receptor inhibits 1α-hydroxylase of vitamin D, and contributes to calcium reabsorption and phosphate excretion in the kidney.

초등 영어교육을 위한 동화의 활용

전은실 이화여자대학교 사범대학 교과교육연구소 2006 교과교육학연구 Vol.10 No.1

동화는 언어학습의 자료로서 많은 장점을 가지고 있다. 특히 어린이 영어교육에 활용될 경우 다양한 활동으로 연결될 수 있으며 듣기, 말하기, 읽기, 쓰기를 통합적으로 학습할 수 있게 해준다. 본 연구는 동화의 텍스트 구조상의 특성과 언어적인 면에서의 특성을 살펴보고 언어교육자료로서 동화가 어떤 장점을 가지는지 논의하고 있다. 그리고 수많은 동화책 중에서 적절한 이야기를 고르는 것은 쉬운 일이 아니므로, 내용과 구성, 동화 속에 함축된 가치관과 태도, 문화적 정보, 언어적 수준, 그림의 사용, 기타 학습을 도울 수 있는 반복적 언어 사용 등을 고려하여 학습자의 흥미와 언어 능력에 적절한 동화를 고를 수 있도록 여러 가지 기준을 제시한다. 또한 동화를 활용하는데 가장 중심이 되는 스토리텔링은 어떻게 이야기하느냐에 따라 학습 효과가 달라질 수 있는데 목소리의 크기와 억양, 높낮이를 이야기의 내용에 맞게 조절하고 속도와 얼굴표정 등에 변화를 주는 것이 흥미를 높이고 이해를 도울 수 있다. 그리고 이야기하는 과정에 학습자의 적극적인 참여를 유도하는 것도 중요하다. 그 밖의 단어와 사전 학습, 길잡이 질문의 제시 등의 내용 이해를 돕기 위한 활동, 역할 놀이나 대화의 연습 등을 통한 유창성 향상을 위한 활동, 그림이나 글로 이야기에 대한 반응을 표현하도록 하는 활동 등의 실제 이야기 중심의 수업에 활용될 수 있는 다양한 활동 들이 소개되고 있다. Stories as language teaching and learning materials are valuable resources for language learners. When stories are used in primary English teaching, they can easily lead to various language learning activities. They also provide opportunities for students to practice listening, speaking, reading, and writing skills, and have an important role in integrating the four skills in classrooms. The purpose present study is to review the discourse organization of stories and characteristics of language use in stories. The advantages of story use as language teaching materials are also discussed. It is not an easy task to choose suitable storybooks since so many of them are available. The study presents several criteria for selecting storybooks such as content, organization, values and attitude, cultural information, language, illustrations, etc. Those criteria can be helpful for finding out appropriate books considering the students' interest and language ability level. Storytelling is the most central activity of the lesson using a story, and how a story is told is an important factor affecting the students' understanding. It is recommended to vary the pace, tone and volume of the storyteller's voice and to use gestures and facial expressions to help convey the meaning. It is also beneficial to encourage the students to take part in the storytelling. Finally, the study introduces various language learning tasks around stories that the teachers can use in classrooms.

국내 학술지 토익 교육 및 학습 관련 논문 분석

전은실,고미숙 인문사회 21 2020 인문사회 21 Vol.11 No.2

The purpose of this study is to examine the articles related to TOEIC teaching or studying published in Korean academic journals during recent years to review what has been studied in the field. For the purpose, 55 collected articles published since 2005 were analyzed in terms of language skills that TOEIC is to assess, research participants, research methods, and research themes. Regarding research participants, more various groups of students are needed to participate in future studies, and the information on their TOEIC score levels should be provided. Since most studies in recent years adopted qualitative research methods, more qualitative approach would contribute to the diversity in terms of research method. The articles analyzed explored diversified topics such as teaching methods, online and blended learning, student-centered learning, strategy, learner motivation, etc. Based on the results of the analyses, a few suggestions were made on the future research in the field. 본 연구는 토익 교육・학습을 주제로 국내 학술지에 게재된 논문을 분석하여 최근까지의 연구 결과를 정리하고자하였다. 그 목적을 위하여 2005년 이후 출판된 55편의 관련 논문을 수집하고, 연구된 토익 시험 분야, 연구 대상자, 연구 방법, 연구 주제를 기준으로 분류를 시도하였다. 연구 결과 연구 대상자면에서는 대학생 외 보다 다양한 집단의 연구 참여자를 대상으로 하는 것이 필요하고 연구대상자의 토익 점수 수준에 대한 정보가 반드시 제공되어야 할 것으로 생각된다. 대부분의 논문들에서 양적 연구방법이 사용되고 있는 바, 질적 연구 방법의 더 많은 활용이 연구의 다양성 측면에서 필요하다. 분석 대상 연구들은 특정한 교수법, 온라인 및 블렌디드 러닝, 학습자중심 교육, 전략 사용, 학습 동기 등 다양한 주제를 다루고 있었는데, 분석 결과를 바탕으로 앞으로의 연구 방향이 제시되어 있다.

HBeAg 양성인 사구체신염에서의 alpha - interferon 치료

전은실,정우경,윤형진,안규리,한진석,김성권,이정상 대한신장학회 1994 학술대회및초록집 Vol.13 No.2