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Fluoxetine 투여 후 Amitriptyline의 혈장농도 변화
전용호,권영준,정희연,한선호,Jun, Yong-Ho,Kwon, Young-Joon,Jung, Hee-Yeon,Han, Sun-Ho 대한생물정신의학회 2001 생물정신의학 Vol.8 No.2
Objective : The purpose of this study was to compare the plasma amitriptyline and nortriptyline level between before and after fluoxetine addition with patients who were currently taking amitriptyline. Method : From the inpatient and outpatient unit of Soon Chun Hyang University Hospital, Chunan, fourteen subjects who were taking amitriptyline 25mg more than 1 week at least were given fluoxetine 20mg. Before and 2 weeks after fluoxetine addition, the plasma level of amitriptyline and nortriptyline are analyzed simultaneously by High Performance Liquid Chromatography(HPLC). At the same times, HAM-D(Hamilton Rating Scale for Depression) score and the UKU(Uldvalg for Klinske Unders${\Phi}$ gelser) side effect scale were checked. Results : After fluoxetine addition to the patients who were taking amitriptyline, the plasma level of amitriptyline, nortriptyline and sum of amitriptyline and nortriptyline had risen. The mean plasma amitriptyline level increased from $168.9{\pm}89.4ng/ml$ to $183.0{\pm}102.0ng/ml$ after fluoxetine addition(p=0.011), but the change was not statistically significant. The mean plasma nortriptyline level increased significantly from $114.3{\pm}70.2ng/ml$ to $168.0{\pm}86.2ng/ml$ after fluoxetine addition(p=0.011). In addition, the mean plasma level of total amitriptyline and nortriptyline increased significantly from $283.1{\pm}125.3ng/ml$ to $350.9{\pm}78.4ng/ml$ after fluoxetine addition(p=0.016). After fluoxetine addition, no significant change was noted in the UKU side effect scale score. Conclusion : As consequence of comparison of plasma amitriptyline and nortriptyline level before and after fluoxetine addition, mean amitriptyline, nortriptyline and total plasma level was increased after fluoxetine addition. This suggests that coadministration of amitriptyline and fluoxetine may induce improvement of depressive symptom in depressive patients by way of increased plasma level of amitriptyline.
디지털 스크롤 압축기를 적용한 시스템 에어컨의 냉난방특성에 대한 실험적 연구
전용호(Young Ho Jun),김대훈(Dae Hun Kim),권영철(Young Chel Kweon),장근선(Keun Sun Chang),이윤수(Yun Su Lee),문제명(Je Myung Moon),윤백(Youn Baek),홍주태(Ju Tae Hong) 대한설비공학회 2003 설비공학 논문집 Vol.15 No.6
In order to investigate the cooling and heating characteristics of a variable-capacity system A/C applying a digital scroll compressor, the cooling and heating capacities and COP are measured by the psychrometric calorimeter. The capacity of the system is controlled by the digital scroll compressor, which is operated by controling PWM valve and the loading vs. unloading time. In the case of unloading compared that of loading, the consumption power of the compressor is about 11% and the capacity variation of the system A/C is within about 1%. When the system A/C is operated under the cooling and heating standard conditions, COP is nearly uniform but cooling capacity and heating capacity increase at minimum, rated and maximum modes. The system A/C applying the digital scroll compressor is effective for the range with high load or the width of large load variation. When the auxiliary heater is on, at the cold region, the system A/C produces the excellent heating capacity.
냉동탑차용 강제대류방식 PCM 축냉시스템 개발 및 현장적용 시험
전용호(Young-Ho Jun),김진홍(Jin-Hong Kim),문진호(Jin-HO Moon),이상렬(Sang-Ryoul Lee),김용찬(Yongchan Kim),정해용(Hae-Yong Jeong) 대한설비공학회 2016 대한설비공학회 학술발표대회논문집 Vol.2016 No.6
The purpose of this study is on the development of a Forced convection type PCM cold storage system for refrigeration truck and on its performance confirmation through an environmental room and a field tests. In this study, for the environmental room test, three cases of cold-storing operation time were examined. Through the test after a storage procedure, the truck indoor temperature was successfully maintained below -18℃ during about 11, 13, and 16hours according to the cold-storing operation times of 7, 9 and 11hours, where the ambient temperature was kept at 30~35℃. Also at the field test, the truck indoor temperature was successfully maintained below –18℃, and it showed excellent recovering performance of indoor temperature less than 20 minutes after a door opening and closing. This excellent temperature recovering performance is the best merit of a forced convection type system.
디지털 스크롤 압축기를 이용한 시스템 에어컨의 냉난방특성
전용호(Young Ho Jun),김대훈(Dae Hun Kim),권영철(Young Chel Kweon),이윤수(Yun Su Lee),문제명(Je Myung Moon),홍주태(Ju Tae Hong) 대한기계학회 2003 대한기계학회 춘추학술대회 Vol.2003 No.4
In order to investigate the cooling and heating characteristics of a variable-capacity system A/C using<br/> a digital scroll compressor, the cooling and heating capacities and EER are measured by the<br/> psychrometric calorimeter. The capacity of the system is controlled by the digital scroll compressor,<br/> which is operated by controling PWM valve and the loading vs. unloading time. When the system A/C<br/> is operated under the cooling and heating standard conditions, EER is nearly uniform but cooling<br/> capacity and heating capacity increase at minimum, rated and maximum modes. When the auxiliary<br/> heater is on, at the cold region, the system A/C produces the excellent heating capacity.