운동과 영양 섭취가 뇌 건강에 미치는 영향

장혁기 한국체육학회 2015 전국체전기념 한국체육학회 학술발표회 Vol.2015 No.-

운동과 식이요법의 병행이 신체구성의 추이에 미치는 영향

장혁기,김재훈,전태원,김용권,이복은,한구석,진영수 대한스포츠의학회 1998 대한스포츠의학회지 Vol.16 No.1

The purpose of this study was to investigate the effect of the aerobic exercise and weight training combined with low-calorie diet on the changes of the body composition during 12 weeks. The subjects were selected with 10 females over 30% body fat without risk factor during training. They did not have attended in any obese therapy course before. Exercise regimen was composed with aerobic exercise and weight training program, 2hrs·day-1, 4days·week-1. The intensity of aerobic exercise and weight training were 50% of HRR, 50% of 1RM(10 rep., 3sets) respectively. The calorie restrict regimen was LCD(low-calorie diet) of 1000∼1500 kcal·day-1(approximately 15 kcal per kg). The body composition was measured to the weight, %body fat, FFM, WHR at pre-test, 3, 6, 9 and 12week. The one-way repeated ANOVA was used and Duncan was treated for the post hoc testing(p<.05). 1. Body weight was decreased from pre-test to 12week by 11.8±4.0kg. The changes of the weight was significantly decreased among from pre-test to 3, 3 to 6 and 6 to 9 week(p<.01). There was not significantly different during 9 to 12 week(p<.05). 2. %Body fat was decreased from pre-test to 12week by 10.8±3.2%. The change of %body fat was significantly decreased among from pre-test to 3, 3 to 6 and 9 to 12 week(p<.01). There was not significantly different during 6 to 9 week(p<.05). 3. FFM was decreased from pre-test to 12 week by 4.6±4.7kg. The change of FFM was significantly decreased during the whole test(p<.05). 4. WHR was decreased by 4.8±5.8 from pre-test to 12 week. The change of WHR was significantly decreased from 3 to 6 week(p<.01). There was not significantly different from pre-test to 3, 6 to 9 to 12 week(p<.05).

학령기 비만이 체력 및 혈중지질 수준에 미치는 영향

장혁기 서울여자대학교 자연과학연구소 2014 자연과학연구논문집 Vol.26 No.-

Comparison of lactate threshold, glucose, and insulin levels between OLETF and LETO rats after all-out exercise

장혁기 JOURNAL SPORTS SCIENCE & MEDICINE 2009 JOURNAL OF SPORTS SCIENCE AND MEDICINE - Vol.8 No.3

청소년 건강증진을 위한 국제 학교정책적 노력

장혁기 한국스포츠교육학회 2010 한국스포츠교육학회 학술발표논문집 Vol.2010 No.12

뇌의 Orexin 발현과 운동 : 스트레스 조절 인자로서의 역할

장혁기 서울대학교 스포츠과학연구소 2008 스포츠과학리뷰 Vol.2 No.1

Orexins (Orexin A & B) are hypothalamic peptides of brain most recognized for their significant effects on feeding and arousal. Physiologically the orexin system has been implicated in the regulation of behaviours that are associated with wakefulness, locomotion, and stress. Central orexin activates hypothalamo-pituitary-adrenal (HPA) axis and may be involved in stress-induced activation of the HPA axis, resulted in a dose-dependent elevation of circulating adrenocorticotropin (ACTH) and corticosterone related with stress regulation. Both Orexin 1 receptor and 2 receptor have been found in the general area of the hypothalamus, but their localizations are region-specific : OX-2R mRNA is predominant in the paraventricular hypothalamic nucleus (PVN) region. The PVN area is innervated by OX-A and OX-B immunoreative projections, which both originate from the lateral hypothalamic area and perifornical nucleus. Those projections suggest an action of endogenous orexin on ACTH release, either by neuromodulatory effects in the PVN, or by neuroendocrine actions in the pituitary gland following release into the median eminence. Swimming and running exercise in rats activated orexin neuron in the brain and central administration of Orexins increased physical activity. Orexins is important not only stress regulating but also physiological regulator about exercise. But, the study of orexin about exercise is not enough for knowledge of the mechanism. Orexin은 중추 섭식 조절인자로서 밝혀진 이래에 뇌의 시상하부에서의 다양한 조절인자로서 역할하는 것이 많은 연구를 통해서 밝혀졌다. 그 조절로는 섭식조절을 비롯하여 수면·각성 조절, 자율신경계 조절, 스트레스 조절 등이 있다. 특히, 생체가 스트레스를 받으면 시상하부로부터 시작되는 HPA축이 활성화하는데 이를 조절하는 상위레벨의 조절인자로 Orexin이 발견되었다. 이 Orexin 의 발견으로 스트레스 기전의 새로운 개념도가 형성되었고, 운동 스트레스시에도 관련되며, 그 조절 인자로서의 역할에 대해 연구되기 시작되었다. Orexin은 식욕을 조절하는 뇌의 외측시상하부에서 발현하는 단백질로 뇌의 여러 부위에 그 수용체가 존재하는 것으로부터 생리적으로 복잡하고 많은 조절에 관여한다. 스트레스 호르몬인 ACTH 분비를 자극하는 CRH가 많이 존재하는 부위인 PVN에 Orexin 수용체가 존재함으로써 HPA축의 조절에 중요한 역할을 하는 것으로 여겨져 그 연구가 시작되었다. 최근의 몇몇 연구를 통하여서는 수영 및 런닝 운동이 뇌의 Orexin 신경을 활성화시키는 것을 밝혀내었으며, 쥐에게 외인성 Orexin의 투여가 자발적 신체활동을 증가시켰다. 이처럼, 운동학적으로 Orexin은 스트레스뿐만 아니라 운동에 대해 생리적으로 중요한 조절 인자임이 밝혀지고 있다. 하지만, 아직 운동 분야에서 Orexin이 역할과 관련성에 대한 연구는 미비한 실정이다.

The potential role of creatine supplementation in neurodegenerative diseases

장혁기,임예현 한국운동영양학회 2023 Physical Activity and Nutrition (Phys Act Nutr) Vol.27 No.4

[Purpose] The maintenance of energy balance in the body, especially in energy-demanding tissues like the muscles and the central nervous system, depends on creatine (Cr). In addition to improving muscle function, Cr is necessary for the bioenergetics of the central nervous system because it replenishes adenosine triphosphate without needing oxygen. Furthermore, Cr possesses anti-oxidant, anti-apoptotic, and anti-excitotoxic properties. Clinical research on neurodegenerative illnesses has shown that Cr supplementation results in less effective outcomes. With a brief update on the possible role of Cr in human, animal, and in vitro experiments, this review seeks to offer insights into the ideal dosage regimen. [Methods] Using specified search phrases, such as “creatine and neurological disorder,” “creatine supplementation and neurodegenerative disorders,” and “creatine and brain,” we searched articles in the PubMed database and Google Scholar. We investigated the association between creatine supplementation and neurodegenerative illnesses by examining references. [Results] The neuroprotective effects of Cr were observed in in vitro and animal models of certain neurodegenerative diseases, while clinical trials failed to reproduce favorable outcomes. [Conclusion] Determining the optimal creatinine regime for increasing brain creatinine levels is essential for maintaining brain health and treating neurodegeneration.

KI-novation - 2009년은 KISA 직원의 전문성 강화의 해

장혁기,Jang, Hyeok-Gi 한국정보보호진흥원 2009 정보보호뉴스 Vol.137 No.-

대부분의 사람들이 좋은 배우자를 찾는데 투자하는 노력과 정성에 비해 그렇게 찾은 좋은 배우자를 유지, 관리하는 데는 상대적으로 소홀하다고 한다. 조직의 경우도 똑같은 과오를 범하는 경우가 많다. 훌륭한 인재를 구하기 위해 막대한 비용과 시간을 들여 채용절차를 거치지만, 막상 채용을 하고나면 인적자원 개발 및 관리에 무관심해 좋은 인재가 재능을 펼치지 못하고 무기력해지거나, 조직 내에서 비전을 찾지 못하고 이직하게 되는 경우가 많다. 이 같은 문제를 예방하기 위해 조직은 무엇을 해야 할까?

단기간 기관지 삽관후의 음성의 변화

장혁기,강무완,최정환,유영삼,우훈영,윤자복 대한후두음성언어의학회 2000 대한후두음성언어의학회지 Vol.11 No.1

Background and Objectives : To assess the role of altered vocal function in transient voice change after short-term endotracheal intubation, we evaluated acoustic parameters, aerodynamic parameters, and laryngoscopic characteristics preoperatively and postoperatively. Materials and Methods : Vocal function of 10 patients undergoing tympanoplasty and mastoidectomy using general anesthesia and endotracheal intubation were studied preoperatively, at 1day and 7 days after extubation. Acoustic analysis, aerodynamic study, and telescopic examination were used to assess vocal function. Results : In acoustic parameters, there was no significant difference between preoperative and postoperative measures. However, in subglottic pressure, ere was a significant decrease at 1 day after extubation and this change was return to preoperative value at 7 days after extubation. MPT(Maximal Phonation Time), MER(Mean flow Ratio), and VC(Vital Capacity) were decreased 1 day after extubation but did not show statistically significant change. Three of 10 patients manifested a vocal fold edema and injection 1 day after extubation. Conclusions : Subglottic pressure revealed a significant decrease at 1 day after extubation. And this change was correlated with laryngeal morphologic change and decrement in pulmonary function.

학급 집단 음악줄넘기 프로그램이 비만 아동의 신체구성, 체력, 혈중지질에 미치는 영향

장혁기(Chang, Hyukki),김성기(Kim, Sung Ki),서동일(Seo, Dong Il) 한국보건간호학회 2011 韓國保健看護學會誌 Vol.25 No.1

Purpose: The study investigated the effects of 9 weeks of group music rope-jumping training on health-related physical fitness and blood lipid in obese elementary school boys and girls. Method: Subjects were randomly assigned to either a training group (37 boys and 18 girls) or control group (36 boys and 19 girls). The training group exercised for 1 hour, 2 days per week during the 9-week supervised music rope-jumping training program. The control group was asked to maintain their normal daily physical activities. The effects of the interventions on physical fitness and blood lipids were analyzed by two-way repeated measures ANOVA (group × time). Results: There were significant group x time interaction effects on body weight (p<.023), %body fat (p=.09), body mass index (p=.018), and body fat mass (p=.019) in school girls. However, there was not an interaction effect on serum lipids in both genders. Conclusion: The 9-week music rope-jumping training program used was effective for improving body composition in obese elementary school girls.