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장용석,민건우,정지천,Jang, Yong-Suk,Min, Gun-Woo,Jeong, Ji-Cheon 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.2
Objective : Peroxynitrite $(ONOO^-)$, formed from the reaction of $O_2^-$ and NO, is a cytotoxic species that can oxidize several cellular components such as proteins, lipids and DNA. It has been implicated in the aging process and age-related disease such as Alzheimer's disease, rheumatoid arthritis, cancer and atherosclerosis. The aim of this study was to investigate scavenging activities of $ONOO^-$ and its precursors. NO and $O_2^-$ and its scavenging mechanism using fluorescent probes, DCFDA, DAF-2 and DHR 123.. Methods : Psoralea corylifolia was crushed. The crushed Psoralea corylifolia was extracted 3 times, each time with 3 volumes of methyl alcohol at $60^{\circ}C$ for 24 h. The extract was filtered and evaporated under reduced pressured using a rotary evaporator to yield 16g. This was done to investigate scavenging activities of $ONOO^-$, NO, $O_2^-$ and its scavenging mechanism using fluorescent probes, DCFDA, DAF-2 and DHR 123. Results : After Psoralea corylifolia was added authentic $ONOO^-,\;{\cdot}\;O_2^-$ and NO was markedly scavenged. Also, $ONOO^-$ induced by $O_2^-$ and NO (these derived from SIN-1) was inhibited. The data showed a decrease in $ONOO^-$ mediated nitration of tyrosine through electron donation after Psoralea corylifolia was added. Data showed a dose-dependent correlation with inhibition of nitration of bovine serum albumin induced by $ONOO^-$, Furtheremore, LPS-induced ROS and RNS generation was blocked. Conclusions: These results suggest potential for use of Psoralea corylifolia as an effective $ONOO^-$ scavenger to counter the aging process and age-related diseases.
간이정신진단검사를 이용한 구강작열감 환자의 심리학적 분석
장용석,태일호,고명연,안용우,Jang, Yong-Seok,Tae, Il-Ho,Ko, Myung-Yun,Ahn, Yong-Woo 대한안면통증구강내과학회 2008 Journal of Oral Medicine and Pain Vol.33 No.1
Personality characteristics of BMS patients were alalyzed psychologically by using the SCL-90-R. 59 BMS patient were subjected at Orofacial pain clinic, Department Of Oral Medicine, Pusan National University Hospital during the period from 2006 to 2007. The control group were subjected at dental clinic during the same period. 1. BMS patients group, Dental new patient group, Adult citizen groups were within normal range. 2. The T-scores of HOS, PHOB,PAR, PSY in BMS patient groups was significantly low. 3. The mean T-scores of male in BMS patients group shows the lowest HOS scale, the mean T-scores of female in BMS patient group shows the lowest PHOB scale. 4. The mean T-scores of female in BMS patients group show higher SOM, O-C, DEP, ANX, PSY scales. 5. As compared with the mean T-scores of acute and chronic group in BMS patients, there was no significant difference of the scales.
Notes on Unrecorded Fleshy Fungi of Cordyceps in Korea
장용석,홍순우,Jang, Yong-Suk,Hong, Soon-Woo The Korean Society of Mycology 1986 韓國菌學會誌 Vol.14 No.1
동충하초 속에 속하는 균류로 여겨지는 40여 개체의 표본을 관찰한 결과 6종의 한국산 미기록종이 동정되었기에 보고하는 바이다. 미기록 종은 벌유충 동충하초(Cordyceps alboperitheciata), 파리 동충하초(Cordyceps discoideocapitata), 균핵 동충하초(Cordyceps intermedia), 검은 동충하초(Cordyceps nigrella), 붉은 동충하초(Cordyceps roseostromata), 딱정벌레 동충하초(Cordyceps scarabaeicola) 등이다. 여기에 인용된 표본은 서울대학교 미생물학과 표본실에 보관되어 있다. More than 40 samples of the genus Cordyceps were collected and investigated. Among them, six species were confirmed as unrecorded ones in Korea. Unrecorded species were Cordyceps alboperitheciata, Cordyceps discoideocapitata, Cordyceps intermedia, Cordyceps nigrella, Cordyceps roseostromata and Cordyceps scarabaeicola.
다변량 분석에 의한 국내산 대추나무 품종의 형태적 특성과 유연관계
장용석(Yong Seok Jang),이문호(Moon Ho Lee),황석인(Suk In Hwang) 한국자원식물학회 2006 한국자원식물학회지 Vol.19 No.1
대추나무에 관한 연구 및 2008년부터 시행될 산림수종의 품종보호제도에 대비하여 대추나무의 특성조사요령검정지침서(TG : Test guidelines) 작성 등에 활용할 수 있는 기초자료를 제공하고자 우리나라에서 가장 많이 재배되고 있는 대추나무 복조 등 5품종을 대상으로 과실과 엽의 형태적 특성들을 조사, 주성분분석 및 군집분석 등과 같은 다변량 분석법을 이용하여 분석 고찰한 결과, 인(仁)과 관련된 특성에서는 유의성이 인정되지 않아 대추나무의 품종간 유연관계를 고찰하는 특성으로는 부적절 한 것으로 판단된다. 과실중량을 비롯한 모든 특성들에서 보은대추 품종이 복조를 비롯한 다른 4품종과는 형태적 특성에서 명확하게 구분되는 것으로 나타났다. 주성분분석 결과, 제1주성분의 고유값은 10.45로 전체 분산에 대하여 65.3%의 기여도가 있는 것으로 분석되었으며, 고유 값이 1이상인 제3주성분까지의 전체 분산에 대한 기여도는 96.5%로 매우 높은 것으로 나타났다. 특히, 과실종경을 비롯하여 엽장과 엽병장 및 정엽장과 정엽폭, 과형지수와 핵형지수 및 정엽형지수와 같은 형태적 특성들이 대추나무 품종의 유연관계를 구명하는데 높은 기여도를 나타내는 것으로 분석되었다. 군집분석 결과, 거리수준 3.3을 기준으로 보은대추를 제외한 무등과 월출 및 금성과 복조품종이 포함된 I group과 보은대추 품종만이 포함된 II group등 크게 2개의 group으로 구분할 수 있었으며 I group은 무등과 월출 및 복조품종이 포함된 sub group과 금성 품종 등 2개의 sub group으로 다시 구분할 수 있었다. The objectives of this study, an analysis of fruit and leaf morphological characteristics among the five Zizyphus cultivars could be used for the investigation of cultivars classification and could provide information to make out the UPOV TG(Test Guidelines). ANOVA tests showed that there were statistically significant differences in all fruit and leaf morphological characteristics among the five Zizyphus cultivars at 1% level. But, for kernel characteristics, differences were statistically non-significant among the cultivars. Approximately, the Wolchul and Boeun cultivars showed larger and smaller values in overall characteristics and cultivars, respectively. The results of principal component analysis(PCA) for the fruit and leaf morphological characteristics showed that the first for principal components(PC s) explained about 65.3% of the total variation. The first PC was correlated with those characteristics that were mainly related to the terminal leaf length(TLL), leaf length(LL), fruit length(FL), terminal leaf width(TLW), and leaf petiole length(LPL). The second and third PC was mainly correlated with the terminal leaf morphological index(TLMI). Therefore, these characteristics were important to analysis of the fruit and leaf morphological characteristics and classification among the five Zizyphus cultivars. Cluster analysis using UPGMA method based on principal components showed that five Zizyphus cultivars could be clustered into two groups. Group I comprises Mudung, Wolchul, and Bokjo and Geumsung cultivars, Group II is Boeun cultivar. These results well similar to that of principal component analysis.
장용석 ( Yong-suk Jang ),이춘우 ( Chun-woo Lee ),최규석 ( Kyu-suk Choi ) 한국수산해양기술학회 2021 수산해양기술연구 Vol.57 No.4
The Korean stow net is a fishing method that utilizes the changing direction of the net entrance with the tidal current. This study attempted to obtain basic data from the recent offshore stow net fisheries to improve the gear by analyzing the dynamic behavior of the nets affected by current speed and direction using computer simulations. A numerical calculation was performed at a current speed of 0.5 knot between 2.5 knot at each 0.5 knot. The time taken for the gear opening was the longest from 0.5 knot at 1,500 seconds and the shortest from 2.5 knot at 450 seconds in the simulations. In all cases, the net width and tension at net deployment gradually decreased as the current speed decreased. However, the net height tended to increase inversely proportional to the current speed. During the net rotation, the net height was maintained at all cases. The net width and tension fluctuated, but the regularity was very low. In this study, the calculated simulation data showed that the opening efficiency decreased proportional to the current speed. The opening efficiency is related to the catching efficiency; therefore, it is necessary to improve the gear to enhance its opening efficiency.
[디젤엔진부문] 투명 아크릴 모델을 이용한 디젤 인젝터 노즐에서의 캐비테이션 유동에 관한 연구
장용석(Yongsuk Jang),김만식(Manshik Kim),민경덕(Kyoungdoung Min) 한국자동차공학회 2001 한국자동차공학회 춘 추계 학술대회 논문집 Vol.2001 No.11_1
Experiment was conducted in transparent acrylic nozzle model which was scaled up by 10 times in order to study the behavior of cavitation flow inside the nozzle holes. High speed CCD camera was used to visualize the flow inside sac chamber and holes. Refractive index matching technique was also used to prevent distortion of images. Reynolds number and Cavitation number was simultaneously matched in the same range of the real injector by means of controlling the flow rates and pressures.<br/> The experimental results shows that the difference between cavitation layer and liquid layer causes very turbulent flow inside the nozzle hole and the effect of needle lift is the dominant factor that determines the behavior of the cavitation flow pattern.<br/> In the low lift case. due to the transient nature of turbulent flow within the sac volume. string cavitation from one hole to another hole occurred in intermittent way<br/>
장용석(Yongsuk Jang),이명진(Myungjin Lee),신태영(Taeyoung Shin),김승현(Seung-Hyun Kim),성지은(Jieun Seong),김성아(Sung-A Kim),최용인(Yongin Choi),이혜숙 과학기술정책연구원 2016 정책연구 Vol.- No.-
The purposes of this study are three-folds. First, it introduces the globally discussing concept of ‘Inclusive Innovation’ to Korean policy arena and tries to enhance its concept. For this purpose, it reviews various international and domestic literatures on innovation policies for inclusive growth in the context of various global initiatives including UN SDGs. It also analyses possible working mechanism on how innovation can achieve both inclusiveness and growth. Second, this study reviews diverse Korean policies from the angle of ‘Inclusive Innovation’ and develop several successful policy cases that can be contributed to the global discussion. It overviews past and current Korean polities in four different aspects including social, territorial, industrial and gender inclusiveness. It identifies five prominent policy cases and contributes them to the OECD’s Policy Toolkit for inclusive innovation, which are presented in the appendix. Third, this study extends the scope of ‘Inclusive Innovation’ to the global dimension and tries to develop innovation strategy that can enhance global inclusiveness. It argues that global society should pay more attention on widening North-South gaps, which are largely resulted from widening innovation capacities, and need to develop effective innovation strategies that help low-income and developing countries in promoting their innovation capacities. It proposes several specific programs that global society can deliver together including expansion of Appropriate Technology Centers for helping especially low-income countries, programs for strengthening STI related institutional and policy capacities of developing countries, and sustainable operation of educational and training programs. There are a couple of remaining challenges or future tasks. One is conceptual elaboration of ‘Open and Inclusive Science’ framework and its application to the global inclusive innovation efforts. Another is innovation policy for generation inclusiveness - i.e., reducing gaps between generations possibly caused by current innovation policies.