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폐쇄성 수면무호흡증 환자에서 구개수구개인두성형술 후 폐용적의 변화
강기석,장백암,백승훈,김은석,강정한 대한이비인후과학회 2002 대한이비인후과학회지 두경부외과학 Vol.45 No.1
Background and Objectives:The objective of this research was to study the change of lung volume after uvulopalatoph-aryngoplasty (UPPP) in obstructive sleep apnea (OSA) patients. Materials and Methoid:Eight OSA patients were pa-rticipated in this study. These patients were treated with UPPP at Seoul adventist hospital. Vital capacity (VC), inspiratory capacity (IC), expiratory residual volume (ERV) and FEV1, FEV1/FVC, FEV25-75% were determined by standard spirometry at the preoperative, at 3 postoperative days and 1 postoperative month. Results:Vital capacity (VC) was significantly larger at 3 post-operative days (3.58± 0.87 L, mean± SD) than those at pre-operative (3.12± 0.69 L, mean± SD)OSA (p=0.047). FEV1 (L) was larger at 3 post-operative days (2.91± 0.76 L, mean± SD) than those at pre-operative (2.68± 0.85 L, mean± SD), but was not significantly correlated statically (p=0.249). Conclusion:We found significant core-lation betwen preopeative and postoperative VC, IC. (Korean J Otolaryngol 2002;45:51-5)
김명원,이종환,김은석,이상철,장백암,변영자 대한기관식도과학회 1998 大韓氣管食道科學會誌 Vol.4 No.2
Background and Objectives: The most common cause of the failure of endoscopic dacryocystorhinostomy is closure of the osteotomy site due to granulation or adhesion. We used mitomycin-C, an antineoplastic antibiotic agent, soaking over the osteotomy site to suppress fibrous proliferation and scar formation during the endoscopic dacryocystorhinostomy. Materials and Methods : A total of 20 Patients diagnosed with nasolacrimal duct obstruction were assigned randomly to either a mitomycin-C group or a control group. Endoscopic dacryocystochinostnmy has been used in both groups. In the mitomycin-C group, a piece of merocel soaked with 0.2 mg/ml mitomycin-C was applied to the osteotomy site and then after 30 minutes was removed. Results : All patients in the mitomycin-C group remained symptom free after removal of their silicone tube (100% success), and there were two patients in the control group who had recurrent epiphora (67% success). In the mitomycin-C group, the average surface area of the osteotomy at the end of the sixth postoperative month was 4.1 $\textrm{mm}^2$, whereas that of the control group was 2.5 $\textrm{mm}^2$. Neither serious systemic nor local toxicity were noted in the mitomycin-C group. Conclusion : Intraoperative mitomycin-C may possibly improve success rates over the endoscopic dacryocystorhinostomy procedure.