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- 저자 : 장경진 (검색결과 172 건)
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장경진,배춘식,전학진,조용성 한국임상수의학회 1997 한국임상수의학회지 Vol.14 No.1
This experiment was performed to investigate the leptospiral antibody in dairy cattle with serological test in three areas of Kangwondo from February to June, 1995. Twelve different living antigen's (S icterohemorrhagiae, Lpomona, L hardjo, L australis, L canicola, L autumnalis, L grippotyphosa, L tarassovi, L pyroenes, L bataviae, L hebdomadis and L ballum) of Leptospira interrogans were used for the serological test in dairy cattle. The blood samples of 130 cattle were examinde by microscopic agglutination test. Among the serum samples of the dairy cattle, 5 heads of the dairy cattle (3.8%) were positive. Among the positive samples of 5 heads, 3 heads of dairy cattle (2.3%) showed the antibody of L canicola, 2 heads of dairy cattle (1.5%) showed the antibody of L icterohaemorrhagiae. Positive rate by age was 0% ($\leq $2year), 4.6% (3~4year) and 6.6% ($\geq $5year).
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The Role of 18F-FDG PET/CT as a Prognostic Factor in Patients with Synovial Sarcoma
장경진,임일한,박준연,조아라,공창배,송원석,조완형,이수용,고재수,김병일,최창운,임상무 대한핵의학회 2015 핵의학 분자영상 Vol.49 No.1
Purpose This research aims to investigate the potential of 18Ffluorodeoxyglucosepositron emission tomography/computedtomography (FDG PET) to predict pathologic response afterneoadjuvant chemotherapy (NAC) and overall survival (OS)of patients with synovial sarcoma in Korea. Methods Twenty patients with synovial sarcoma fromJanuary 2001 to December 2011 were reviewed retrospectively. All patients underwent pre-treatment FDG PET and tumorremoval. Patients were classified with the maximum SUV(SUVmax), metabolic tumor volume (MTV), total lesion glycolysis(TLG), age, sex, histologic subtype, tumor size, NAC,resection margin, and metastasis at diagnosis. Pathologic responsewas assessed using the French Federation of CancerCenters system. Statistical analyses were analyzed using theKaplan-Meier method, log-rank test, Cox proportional hazardsregression model, and Mann-Whitney test. Results Nine patients (45 %) showed pathologic response,and ten patients survived. Higher SUVmax, higher MTV,higher TLG, monophasic epithelial type, and metastasis atdiagnosis were significantly related to poorer OS (p=0.047,0.016, 0.016, 0.045, and 0.018, respectively). By multivariateanalysis, metastasis at diagnosis was significantly related topoorer OS (p=0.012/HR=5.9, 95 % CI 1.47 to 24.1). TheSUVmax, MTV, and TLG of the non-responder group weresignificantly higher than those of the responder group (p=0.020, 0.020, and 0.020, respectively). There was no significantdifference in size between the two groups (p=0.062). Conclusions A higher SUVmax on the pre-treatment scan,monophasic epithelial type, and metastasis at diagnosis weresignificantly associated with a poorer OS, and pathologicresponders showed a higher SUVmax before NAC. ThePET parameters can be used to predict OS and pathologicresponse in patients with synovial sarcomas before NAC.
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