http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
강광숙,임철완 ( Kwang Suk Kang,Chull Wan Ihm ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.4
A Case of Addison`s Disease Kwang Suk Kang, M.D., Chull-Wan Ihm, M.D Departement of Dermatology, Chonbuk National University Medical school, Chonju, Korea. We report a case of the Addison`s disease, presenting only skin changes without other symptoms of the disease. The patient was a 24-year-old-female, whose chief complaints were dark pigmentation of the skin and mucous membrane and scanty hairs of the axilla and pubic area. Laboratory findings disclosed decreased plasma cortisol, decreased urinary 24hrs` 17-ketosteroid and 17-hydroxycorticoid and inceased plasma ACTH. The ACTH stimulation test failed to rise the plasma cortisol. (Kor J Dermatol 29(4) : 538-543, 1991)
한국인에서의 기저세포암의 임상 및 병리조직학적 연구 -대한피부과학회 피부병리 연구분과위원회 공동연구-
임철완(Chull Wan Ihm),손숙자(Sook Ja Son),김방순(Bang Soon Kim),고재경(Jai Kyoung Koh),조백기(Baik Kee Cho),김시용(Si Yong Kim),원영호(Young Ho Won),김종민(Jong Min Kim),송은섭(Eun Sup Song),김수남(Soo Nam Kim),서기석(Kee Suck Suh),조 대한피부과학회 2000 대한피부과학회지 Vol.38 No.6
Background:Basal cell carcinoma(BCC) does not commonly occur in dark-skinned people, although it is the most common cancer of light-skinned people. So it has been known that incidence of BCC is lower than that of squamous cell carcinoma(SCC) in Asian and Africans. However, several recent Korean articles have reported the reversal of the ratio of SCC to BCC. There has been no report about BCC following a nationwide survey in Korea. Objective:Our purpose was to confirm the trends in BCC and SCC, and to identify the clinical and histopathological characteristics of BCC. Methods:A clinical and histopathological analysis was done retrospectively with patients diagnosed as BCC from the Department of Dermatology of 15 University Hospitals or General Hospitals during the last 20 years(1977-1996). Annual incidence of BCC was compared with that of SCC at the same situation. We compared the results with those in other races statistically. Results:1. Incidence of BCC was 0.16% compared with 0.11% of SCC. The increasing incidence of BCC was more pronounced than that of SCC, although they were increased gradually. 2. The male-female ratio was 1:1.07, and the most frequent age group was the 6th decade(30.1%). 95% of the patients were older than the age of 40 years with the mean age of 62.7 years. 3. The most commonly involved site was the face(84.9%), especially on the nose, cheek, and eyelids. 4. The most frequent histologic pattern was nodulocystic type(35.4%), followed by mixed(30.1%), infiltrative(9.3%), superficial(6.7%), micronodular(6.2%), adenoid(5.9%), metatypical(4.0%), morpheaform(2.1%), and fibroepithelioma type(0.3%). 5. Histologically, 45.3% of BCC contained pigment. The histologic pattern most frequently associated with pigmented BCC was mixed type(53.1%) followed by nodulocystic(51.2%),superficial(46.8%), micronodular(38.6%), and adenoid type(33.3%). 6. Overall recurrence rate was 6.3%. Morpheaform, infiltrative, and metatypical BCC have a high erincidence of recurrence(26.3%, 13.2%, 8.1%, respectively). Therapeutic modalities that showed high recurrence rate was 5-FU, curettage and electrodessication, and cryotherapy(33.3%, 28.6%, 16.8%, respectively). Conclusion:It was confirmed following a nationwide survey that increasing incidence of BCC was more pronounced than that of SCC since early 1980s and BCC was the most common skin cancer in Korea. (Korean J Dermatol 2000;38(6):762~771)
다발성 각화 극세포종이 선행된 급성 발열성 호중구성 피부병
임철완(Chull Wan Ihm),강광영(Kwang Young Kang),김순철(Soon Cheol Kim),전택환(Taek Hwan Jun) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.9
Severe recurrent attacks of acute febrile neutrophilic dermatosis shortly followed multiple keratoacanthoma in a 43-yaear-old man with myelodysplastic syndrome. Besides the typical clinicopathological findings of the syndrome(fever, leukocytosis and neutrophilic erythematous plaques of the skin), the patient showed orolingual and conjunctival ulceration and severe cutaneous pathergic reactions. Moreover, to the best of our knowledge, multiple keratoacanthoma has not yet been reported with relation to the acute febrile neutrophilic dermatosis. (Korean J Dermatol 1999;37(9) : 1310∼1315)
임철완(Chull Wan Ihm),서재일(Jai Il Suh),송은섭(Eun Sup Song),최선필(Seon Pill Choi) 대한피부과학회 1984 대한피부과학회지 Vol.22 No.6
Acral fibrokeratoma, more often called acquired digital fibrokeratoma, is a firm hyperkeratotic horn-like projection of skin surrounded by a slightly elevated epidermial collarette. Most frequently they appear on the finger of adult man. Authors report two cases, one developed on the palm and the other on the ankle. Because of the rarity of these lesions and their even more unusual location, these case were deemed worthy of report.
정상인 피부조직내의 Adenosine Deaminase에 관한 연구 ( 제 II 보 )
임철완(Chull Wan Ihm),김영표(Young Pio Kim),최유섭(Yoo Seop Choi) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.1
Adenosine deaminase (adenosine aminohydrolase, E.C.3. 5. 4. 4; ADA), which catalyzes the deamination of adenosine to yield inosine and ammonia, was characterized in the human penile foreskin. ADA was found to be present in both layers of the skin with slightly higher activity in the epidermis(Epidermis; (7. 2+2. 3) * 10-4 unit/mg protein, Dermis;(5. 7 +1. 9) *10-4 unit/mg protein). The enzyme exhibited a broad pH optimum from 6. 5 to 8. 0 in both layers of the skin, and was heat-labile, being completely inactivated by heat treatment at 70C-75 C for 10 minutes. In contrast to the ADA of other tissue, the enzyme was inhibited by 2 mM of Cu2+, Fe2+ and Co2+ at pH7. 0 in both layers of the skin. The inhibitory effect of Cu2+ on the enzyme was stronger than other metal ions, and the enzyme was completely inactivated by 20 mM of Cu2+ in both layers. The Cu2+ inhibited enzyme activities which were recovered by adding EDTA. From the above results, it is suggested that the enzyme in both layers of the skin are consisted of same types of isozymes.
철 결핍성 빈혈과 동반된 두발의 저색소성 위축 2예 보고
강광숙,임철완 ( Kwang Suk Kang,Chull Wan Ihm ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.6
Iron depletion may be overlooked in patients who do not show frank symptoms of iron deficiency anemia. We found such occasion in two women patients a 20-year-old and an 18-year-old respectively, whose only complaints were thinning and loss of pigmentation of their scalp hairs. Correction of their iron deficiency restored both the d?meter and the pigmentation of the hair shaft to thick, black lustrous condition.
송일문,임철완 ( Il Moon Song,Chull Wan Ihm ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.6
Background: The patients of trichotillomania seem to have received much attent.ion based on patients behavioral psychologic;l aspects, but most of the patients ar e met in dermatological clinics. Dermatological observation of the lesion dose not seem to not sufficient. Qbject: The purpose of this study is to exarnine clinical and histopathological characteristics of the lesion of trichotillomania. Methods : We have observed 28 cases of the trichotillornania and exarnined their cutaneous lesions and histopathological featwres. Histopathological examination with vertical serial sections was done in 21 cases. Because hai folllicles are independent of each other and a usual 5 thickness vertical sect,ion shows only ver y limited numbers of the hair follicles, authors accomplished sectioning of the biopsied scalp tisue to have 300 serial sections cut and 60 representative sections observed to allow the fullest qiiantitative and qualitative examinations of the follicular pathology of the lesion. Results : The important featuies are as follows. 25 cases(89.2%) were under 18 years old with a slight male predorninance(M:F=1.3:1). Only in 2 cases, psychiatric consultation was made. The degree of involvement was vari ble from less than 5%(6 cases) of the scalp up to 100% involvement of the scalp(3 cases). Thr rnean duration of illness was 12.5 months. The involved hair follicles showed one of the following five roots of hairs they are new hairs with tapered ends, broken short hairs, vellus or intermediate hairs, comedone-like hair bodies or empty follicle orifices. Microscopical observation of thr epilat,ed hairs was done in 16 cases, of which in 13 cases there were no telogen roots of terminal hairs, The histopathological results were as follows : 1. Catagen follicles were incr:ased in 20 cases(95.2%). The actual number of catagen follicles was 1386(37.5%) out of a tota 3695 follicles observed in the total examined slides. 2. Trichornalacia were seen ir 11 cases(52.4%). The actual number of hairs with trichomalacia was 195(10.5%) out of a total 1005 hair canals observed. 3. Pigment clumps of the follicular infundibula were seen in 9 cases(42.9%). The actual num- ber of the pigment-laden infundibula was 148(17.9%) out of a total 826 infundibula observed. 4. Destruction of the hair canal wall were seen in 4 cases(19.0% ). The actual number of destructed hair canal wall was 190(10.2%) out of a total 1863 hair canals observed. Hernorrhage around the follicles was not seen. Conclusion : The involved areas of trichotillomania were varied in size up to the whole scalp and showed four different type., of hairs. Histopathologically catagen follicles increased in almost all cases with 37.5% of all follicles examined. Trichomalacia, pigmented clumps, and the destruction of hair canals were seen by less frequently. (KOrean J Dermatol 1997;35(B): 1101-1109)