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임은미,권기록,이용현,Lim, Eun-Mee,Kwon, Ki-Rok,Lee, Yong-Hyun 대한약침학회 2006 Journal of pharmacopuncture Vol.9 No.1
Purpose : Bee Venom Acupuncture(BVA) is known to affect inflammation and immune system. This study examined the macroscopic, hormonal and immunological effects of BVA on rats with surgically induced endometriosis. Methods : Endometrial tissue was implanted in the serosal wall of the small intestine in rats. The rats were divided randomly into an experimental and control group. The experimental group was treated with BVA injection on kwanwon(CV4) three times per week, and the control group was given an oral dose of normal saline every day. 6 weeks later, the size of the ectopic uterine tissue was estimated, and the serum progesterone, estradiol and cytokine($TNF-{\alpha}$, IL-2, IL-4, IL-6, IL-l0) concentrations were analyzed. Results : The size of the ectopic uterine implants in the experimental group was much smaller than that in the control group. The estradiol, IL-2 concentrations were significantly lower and the IL-6, IL-I0 concentrations were significantly higher in the serum of the experimental group than in the control group, there was no significant difference in the concentration of the other cytokine. Conclusion : These results suggest that BVA is an effective treatment for endometriosis.
예비 유아교사의 음악교수효능감에 영향을 미치는 변인들의 구조적 관계 분석
이옥순(Lee Ok Soon),임은미(Lim Eun Mee) 학습자중심교과교육학회 2019 학습자중심교과교육연구 Vol.19 No.19
본 연구는 예비 유아교사의 음악 교육에 대한 신념, 음악교수내용지식, 음악 활동에 대한 태도, 성취목표지향성, 자기조절학습능력이 음악교수효능감에 미치는 영향과, 음악교수효능감에 영향을 미치는 변인들의 매개 효과를 알아보고자 하였다. 연 구대상은 경기도 소재 대학 유아교육과에 재학 중인 403명의 예비 유아교사였으며, 자료 수집은 설문지를 통해 이루어졌고, 자료 분석은 기술 통계 분석 및 설정한 연구모형의 적합도 지수를 평가하고 각 경로의 인과적 효과를 확인하기 위하여 구조 방 정식 모형 분석을 실시하였다. 결론적으로 예비 유아교사의 음악교수효능감에 직접적인 영향을 미치는 변인은 음악교수내용지식, 음악 활동에 대한 태도 변인이며, 음악 교육에 대한 신념은 음악 활동에 대한 태도를 완전 매개로 음악교수효능감에 간 접적인 영향을 미치는 변인으로 나타났다. 이는 예비 유아교사의 음악교수효능감 향상을 위해 음악교수내용지식이 중요하며, 음악 교육에 대한 신념과 음악 활동에 대한 태도의 향상이 필수적임을 보여준다. This study is purposed to observe the impacts that pre-service early childhood teacher s beliefs about music education, pedagogical content knowledge of music teaching, attitude toward musical activities, achievement goal orientation, and self-regulated learning capability on music teaching efficacy, and examine the mediating effect of attitude toward musical activities, achievement goal orientation, and self-regulated learning capability on pre-service teacher’s music teaching efficacy. The subjects of this study were 403 pre-service early childhood teachers who completed the early childhood music education course in university. Data collection was made through questionnaires, and data analysis were conducted by using frequency analysis, descriptive statistics, correlation analysis, and structural equation model. In conclusion, the variables that directly affect pre-service early childhood teacher’s music teaching efficacy showed that they were pedagogical knowledge of music teaching and music activities, and indirect effects were attitude toward musical activities. This shows that the importance of knowledge of contents of music teaching is important for pre-service teacher’s music teaching efficacy, and it is essential to improve pre-service teacher s beliefs in music teaching and attitude toward music activities.
이보라,임은미,박준식,Lee, Bo-Ra,Lim, Eun-Mee,Park, Jun-Sik 대한한방부인과학회 2005 大韓韓方婦人科學會誌 Vol.18 No.4
Uterine myoma is benign tumor formed from muscular and connective tissues, which is one of the most common tumors found in women's reproductive organs. Uterine myoma is the most common pelvic tumor and they are diagnosed in up to15 to 20% of women in pubertal period. Although myoma is generally considered to be a slowly growing tumor, in 20-40% of women at the age of 35 and more have uterine myoma of significant sizes with severe clinical symptoms. The most common symptoms include abdominal pain or discomfort, low abdominal pressure sensation, hypermenorrhea and urinary symptoms. The treatment of uterine myoma is just observation, operation and hormone replacement therapy. We treated 6 outpatients who has uterine myoma and visited Kyungwon InCheon Oriental Hospital with Herb-medication and acupuncture. So we have gotten good result from them. After 6 outpatients had taken Guichulpazing-tang(歸朮破?湯), the symptoms were improved and the size of the uterine myoma was reduced significantly, It proves that oriental medical treatment is effective on the patients with uterine myoma, but continuous studies are needed.
강녕탕(康寧湯)의 LPS 질내 주입 생쥐에 미치는 항염증(抗炎症) 효과
이태희,윤정문,임은미,김윤상,조현주,Lee Tae-Hee,Yoon Jung-Moon,Lim Eun-Mee,Kim Yoon-Sang,Cho Hyun-Ju 대한한의학방제학회 2004 大韓韓醫學方劑學會誌 Vol.12 No.2
Objective: We made the genital organs inflammatory mice model by vaginal injection of Lipopolysaccharide(LPS), and we intended to make study about anti-inflammatory effects of Gangyeong-Tang, among oral and rectal medication and Herbal-Acupuncture treatment. Method: The female ICR(20-30g) mice were used, the temperature was controlled within $22{\pm}0.5^{\circ}C$ and water and food was not limited. The environment was manipulated to simulate 12 hours of day and 12 hours of night. After LPS injection into vagina, we confirmed on-set of inflammation. 2 days before LPS injection, we started to medicate Gangyeong-Tang in Oral and Rectal and Aqua-acupucture treatment. After 3days from LPS injection, we mesured the White Blood Cell(WBC), Interrleukin-6(IL-6), Tumor Necrosis Factor-${\alpha}$(TNF-${\alpha}$) in blood which was collected from the Retro-orbital Plexus. Results: 1. We made the genital organs inflammatory mice model by vaginal injection of LPS successfully. 2. The number of WBC was decreased significantly as we medicated Gangyeong- Tang in Oral 1g/kg dose, 3g/kg dose and Rectal 1g/kg dose, rectal 3g/kg dose. 3. The concentration of IL-6 was decreased significantly as we medicated Gangyeong-Tang in all group of the Oral, Rectal, Herbal-Acupuncture treatment. 4. The concentration of TNF-${\alpha}$ was decreased significantly as we medicated Gangyeong-Tang in Oral 3g/kg dose and Rectal 1g/kg dose, Rectal 3g/kg dose group. Herbal-Acupuncture treatment group datas showed reductive tendency. Conclusion: As a result of this experiment, we made the genital organs inflammatory mice model by vaginal injection of LPS successfully and demonstrated anti-inflammatory effect of Gangyeong-Tang.