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      • KCI등재

        해방 후 李承燁의 ‘統一民族國家’ 건설운동(1945~1953)

        이현주(Lee, Hyun-Joo) 인천대학교 인천학연구원 2007 인천학연구 Vol.6 No.-

        It was through the process of a merger of three parties that Lee Seung-Yeop rose as a leader of the socialist state movement in South Korea. The inauguration ceremony of the South Korean Worker's Party (남조선노동당) was held under his leadership in November, 1946 after Park Hun-young went to North Korea. He visited secretly PeyongYang accompanied by Kim Sam-yong and achieved the principal that the Opposing Parties individually had to join the South Korean Worker's Party established by centralizing the Korean Communist party. After crossing over the border into North Korea, Lee Seung-Yeop was appointed as a head of judicature of the First Cabinet, North Korea. However, his role was prominent in the Parties. Lee Seung-Yeop rose to the position supervising operations against the South as second secretary of the Party as well as was elected an member of Nine Politics Committeemen of the Korean Workers' Party(조선노동당) which was born due to the merger of Parties. Since then, his activities were concentrated on the leadership for guerrilla war by a partisan. He reorganized a guerrilla unit into three groups in order to develop systematically the guerrilla that was being sporadically progressed in South Korea in July, 1947 and the first group was dispatched to the South in his order. The Korean War was a watershed deciding his fate. He who sent to the South as plenipotentiary of liberated area as soon as the war occurred suddenly was nominated a representative of Seoul city of the Armed Services Committee, North Korea and Seoul temporary Council of People's Commissars the minute that Seoul was occupied. He, an chairman of Council People's Commissars, had to support the People's Army advancing South, recovering ruined product facilities, roads, bridges etc. The management for relief programs, citizens' mobilization, letting volunteer armies go to the war, cultural propaganda programs, land reform, health movement, product power increase was encouraged for about two months. Orders for a guerilla continued. At the same time, Lee Seung-Yeop made people sympathize with the People's Army by infiltrating espionage operators each province, landing the mustered guerrilla to the South through the East Sea on June 25, 1950. Even though his power decreased in the situation an armistice was argued, the first half of 1951, his leadership to the guerrilla was well. The end of the war with Incompletion brought a tragedy to him. Lee Seung-Yeop was arrested with other 11 fellows of the South Korean Worker's Party faction on August 3, 1952. He disappeared in the North, 'a forever strange land', after being sentenced to death and property confiscation upon a quick trial for 4 days, on August from 3 to 6, 1953. The event was not ended in Lee's death. The Purge against the South Korean Worker's Party continued until 1955 and became an overture of the purge against Soviet Union Group(소련파) and Yeon Ahn Group(연안파). His tragic death was not resulted from 'conspiracy of armament riots for the plot against government', but the fact he couldn't clean himself of suspicion even in North Korea, not Kim Il-Sung but Pak Hung-Young whom he assisted as the chief until he died, even if shouting many times 'General Kim Il Sung cheers!' at the official meeting. He failed to free himself from 'a second man of the South Korean Worker's Party until the last moment.

      • SCOPUSKCI등재

        경계성 난소 종양의 보존적 수술 후 불임 환자에서 체외수정시술의 유용성

        이현주,안가영,한호섭,박찬우,양광문,이인호,김태진,임경택,이기헌,강인수,Lee, Hyun-Joo,Ahn, Ka-Yougng,Hahn, Ho-Suap,Park, Chan-Woo,Yang, Kwang-Moon,Lee, In-Ho,Kim, Tae-Jin,Lim, Kyung-Taek,Lee, Ki-Heon,Kang, Inn-Soo 대한생식의학회 2007 Clinical and Experimental Reproductive Medicine Vol.34 No.2

        목 적: 경계성 난소 종양 환자에 있어서 보존적 수술 후 임신에 성공한 군과 비임신 군간 환자의 특성에 차이가 있는지 알아 보았으며, 경계성 난소 종양의 보존적 수술 후 체외수정시술의 유용성에 대해 알아 보았다. 연구방법: 1995년 1월부터 1999년 10월까지 경계성 난소 종양으로 보존적 술을 시행 받은 가임 여성 가운데 임신에 성공한 군 (14명)과 비임신 군 (30명)간 환자의 특성에 차이가 있는지 알아 보았으며, 비임신 군 가운데 불임을 주소로 내원하여 체외수정시술을 시행 받은 5명의 10주기를 대상으로 체외수정시술 결과 및 체외수정시술 후 난소 종양의 재발 유무를 추적 관찰하였다. 결 과: 경계성 난소 종양의 보존적 수술 후 임신에 성공한 군과 비임신 군간 환자의 평균 나이는 25.9세와 27.0세이었으며 혈청 CA-125 수치는 59.7 U/m와 72.0 IU/ml로 비임신 군에서 높은 경향을 보였으나 통계적 유의성은 없었다. 불임을 주소로 체외수정시술을 시행 받은 5명의 10주기 (attempt IVF cycle) 가운데 취소된 2주기를 제외하고 (attempt cycle cancellation rate, 20.0%) 채취된 난자 수는 평균 5.6개 (2$\sim$16개)이었으며 수정율은 14.5% (50.0$\sim$100.0%)이었다. 평균 2.4개 (1$\sim$4개)의 배아를 이식하였으며 배아이식 주기당 임신율과 착상율 및 출생율은 각각 50.0% (4/8 cycle), 31.6% 및 50.0% (4/8 cycle)이었다. 체외수정시술 후 평균 29.6개윌 (14$\sim$61개월)의 추적 관찰 기간 동안 난소 종양이 재발된 경우는 없었다. 결 론: 경계성 난소 종양의 보존적 수술 후 임신에 성공한 군과 비임신 군간 환자의 특성에 차이가 없으며, 보존적 수술 후 체외수정시술의 결과는 비교적 만족할 만한 수준으로 체외수정시술은 경계성 난소 종양의 보존적 수술후 고려될 수 있으나 향후 많은 환자를 대상으로 한 장기간의 추적 관찰을 필요로 한다. Objective: To examine determinants of successful pregnancy and evaluate COH-IVF outcomes of infertile patients after conservative surgical treatment of borderline ovarian tumor (BOT). Methods: In women of BOT (n=93), from January 1995 to December 1999, 44 of 93 women underwent conservative surgical treatment. From theses 44 women, patients characteristics, surgical and histological parameters were compared between 14 women who conceived and 30 women who failed to conceive. For 5 infertile women of 30 women who failed to conceive, 10 attempt IVF cycles were analysed; clinical pregnancy rate (CPR), implantation rate (IR) and live birth rate (LBR). Results: Women who conceived tend to be younger (25.9 vs 27.0 years) and lower serum CA-125 level (59.7 vs 72.9) compared to women who failed to conceive without significant difference. For 8 cycles out of 10 attempt IVF cycles, except for 2 cancellation cycles, the mean number of oocytes retrieved was 5.6 (range 2$\sim$16) with a mean fertilization rate of 74.4%. The CPR, IR and LBR per embryo transfer were 50.0% (4/8 cycles), 31.6% (6/19) and 50.0% (4/8 cycles) respectively. During the mean follow-up period after COH-IVF initiation, 29.6 (range 14$\sim$61) months, no recurrence was found. Conclusion: No determinant of successful pregnancy was found after conservative treatment for BOT. COH-IVF may be considered for infertile patients after conservative treatment of BOT. However, larger clinical studies with longer follow-up are necessary to evaluate the safety and efficacy of COH-IVF. All patients should be informed of the potential risks associated with ovarian hyperstimulation and close follow-up is necessary after COH-IVF.

      • SCOPUSKCI등재

        추황배(Pyrus pyrifolia Nakai cv. Chuhwangbae) 과피로부터 1종의 Sterol과 3종의 배당체 화합물의 단리·동정

        이유건(Yu Geon Lee1),조정용(Jeong-Yong Cho),이현주(Hyun Joo Lee),이용현(Yong Hyun Lee),이상현(Sang-Hyun Lee),한태호(Tae-Ho Han),김월수(Wol-Soo Kim),박근형(Keun-Hyung Park),문제학(Jae-Hak Moon) 한국식품과학회 2013 한국식품과학회지 Vol.45 No.5

        본 연구에서는 배의 유용성 증명을 위한 일환으로 배의 화학성분을 분자수준에서 밝히고자 하였다. 이에 배 과피 MeOH 추출물을 용매분획하여 얻은 EtOAc-산성 분획과 EtOAc-중성분획을 대상으로 Sephadex LH-20, silica gel, 그리고 ODS colmn chromatography와 HPLC를 이용하여 정제 및 단리하였다. 그 결과, EtOAc-산성 분획과 EtOAc-중성 분획으로부터 각각 2종씩의 화합물을 단리하였다. 단리된 화합물 1-4는 1H- 및 13C-NMR 분석을 통하여 각각 (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (화합물 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone(piceoside, 화합물 2), β-sitosterol (화합물 3), 그리고 β-sitosteryl 3-O-β-D-glucopyranoside (화합물 4)로 동정되었다. 단리된 3종의 배당체 화합물(화합물 1, 2, 4)들은 본 연구에 의해 배로부터 처음 동정되었으며, 화합물 3은 추황배로부터 처음 동정되었다. 본 연구결과가 배 함유 성분연구는 물론 배의 기능성 해명 연구에도 추후 중요한 기초자료로 활용되길 기대한다. We isolated and identified antioxidants from acidic and neutral ethyl acetate fractions of the peel of pear (Pyrus pyrifolia N. cv. Chuhwangbae). We isolated 4 compounds from the methanol extract, by using 3 different types of column chromatography (Sephadex LH-20, silica gel, and octadecylsilane) and preparative HPLC. We identified the isolated compounds as (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (compound 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone (picroside, compound 2), β-sitosterol (compound 3), and β-sitosteryl 3-O-β-D-glucopyranoside (compound 4) by nuclear magnetic resonance analysis. We are the first to report the identification of compounds 1, 2, and 4 from pear.

      • KCI등재후보

        광역학요법 후 발생한 맥락막비관류로 인한 급격한 시력저하 1예

        이현주,강지은,이정희,Hyun-Joo Lee Ji-Eun Kang Jeong-Hee Lee 대한안과학회 2005 대한안과학회지 Vol.46 No.8

        Purpose: We report a case of visual recovery in 11 weeks after acute, severe visual acuity decrease without significant fundus change following photodynamic therapy (PDT) for occult choroidal neovascularization (CNV) related to age-related macular degeneration. Methods: A 79-year-old female patient visited our clinic because of decreased vision which had developed 1 week previously in her left eye. Best corrected visual acuity was 0.4 in the left eye. On fundus examination, there were multiple drusen around the fovea, hyperpigmentation and irregular elevation of retinal pigment epithelium, and serous pigment epithelium detachment on the macula. Fluorescein angiogram showed stippled hyperfluorescence with indistinct border in the early phase and hyperfluorescence due to the leakage from CNV of diffuse type ooze in the late phase. ICG angiogram showed focal hyperfluorescence in the mid and late phases. PDT with verteporfin was performed for regression of CNV. The day after PDT, visual acuity decreased to counting fingers at 20 cm and on fundus examination, there was no increase of serous pigment epithelium detachment or subretinal hemorrhage, but only mild retinal edema in the inferonasal area to the fovea. Fluorescein angiogram and ICG angiogram showed only round-shaped hypofluorescence due to choroidal nonperfusion localized to the PDT site. Eleven weeks after PDT, choroidal circulation returned to normal and visual acuity was 0.6. Results: Acute, severe visual acuity decrease after PDT can be developed by choroidal nonperfusion and can be recovered with the improvement of choroidal perfusion.

      • 지신경에 발생한 신경초종 - 8예 보고 -

        이현주,김지수,라인후,박일형,김풍택,Lee, Hyun-Joo,Kim, Ji-Soo,Ra, In-Hoo,Park, Il-Hyung,Kim, Poong-Taek 대한미세수술학회 2012 Archives of reconstructive microsurgery Vol.21 No.2

        As a rare cause of tumor in hand, we report eight cases of neurilemmoma in the digital nerve. Enucleation of the neurilemmoma under the microscopy resulted in complete relief of the symptoms at the latest follow-up.

      • KCI등재후보

        집단검진 환자에서 측정한 안구회선의 범위

        이현주,임기환,Hyun-Joo Lee,M,D,Key-Hwan Lim,M,D 대한안과학회 2005 대한안과학회지 Vol.46 No.10

        Purpose: To determine the range of cyclotorsion in the mass screening of patients by studying the spatial relationship between the optic disc and the fovea. Methods: We examined the horizontal and vertical distances from the center of the optic disc to the fovea using the fundus photographs of 249 subjects (498 eyes) without a past history of strabismus through mass screening and then calculated the optic disc-foveal angle. We studied the differences in all the measured parameters between the right and left eyes and between men and women. Results: The horizontal distance from the center of the optic disc to the fovea was 2.59±0.26 DD (disc diameter) in the right eye and 2.58±0.27 DD in the left eye. The mean horizontal distance was 2.59±0.26 DD. The vertical distance from the center of the optic disc to the fovea was 0.28±0.14 DD in the right eye and 0.30±0.13 DD in the left eye. The mean vertical distance was 0.29±0.14 DD. The calculated disc-foveal angle was 6.26±2.98 degrees in the right eye and 6.69±2.84 degrees in the left eye (mean, 6.50±2.92 degrees). There were no significant differences between the right and left eyes or between males and females. The 95% range of the location of the fovea was from 0.01 DD to 0.57 DD inferior to the optic disc center. Conclusions: We concluded that the clinical location of the fovea, as measured in the mass screening, extends from the center of the optic disc to the lower edge of the optic disc.

      • KCI등재

        말초혈액 자연살해세포가 증가된 반복유산 환자의 탈락막 자연살해세포의 발현

        이현주,김선행,양광문,박동욱,박찬우,홍성란,조동희,송인옥,궁미경,강인수,Lee, Hyun-Joo,Kim, Sun-Haeng,Yang, Kwang-Moon,Park, Dong-Wook,Park, Chan-Woo,Hong, Sung-Ran,Cho, Dong-Hee,Song, In-Ok,Koong, Mi-Kyoung,Kang, Inn-Soo 대한생식의학회 2009 Clinical and Experimental Reproductive Medicine Vol.36 No.3

        목 적: 말초혈액 자연살해세포가 증가된 반복유산 환자군과 증가되지 않은 반복유산 환자군에서 다음 번 유산 시탈락막의 자연살해세포의 발현양상을 관찰하여 말초혈액 자연살해세포와 상관관계가 있는지 보고자 하였다. 연구방법: 말초혈액 자연살해세포가 15% 이상 증가된 반복유산 환자군 14명을 실험군으로, 15% 이하인 군 12명을 대조군으로 하여 연구를 진행하였다. 이 환자들에게서 다음 번 유산 시 착상부위를 포함한 자궁 탈락막 세포를 확인하여 면역조직화학염색을 통해 $CD56^+$와 $CD16^+$ 자연살해세포의 수를 세어 실험군과 대조군을 비교하였다. 결 과: 실험군과 대조군은 탈락막 내 $CD56^+$ 자연살해세포의 수 간에 통계적으로 유의한 차이 ($170.1{\pm}132.1$ vs. $68.3{\pm}66.1$, p=0.02)를 보였으나 둘 간의 상관관계 (r=0.229, p=0.261)는 없었다. 또한 두 군간에 $CD16^+$ 자연살해세포는 통계적으로 유의한 차이 ($25.70{\pm}11.72$ vs. $31.17{\pm}22.67$)를 보이지 않았다. 결 론: 본 연구는 말초혈액 $CD56^+$ 자연살해세포가 증가된 반복유산 환자군에서 말초혈액 자연살해세포가 증가되지 않은 군에 비하여 탈락막의 $CD56^+$ 자연살해세포가 증가되어 있음을 알 수 있었다. 이는 탈락막 자연살해세포가 반복유산의 면역학적 기전에서 중요한 역할을 할 것이라는 가능성을 제시해 주는 연구 결과이며 또한 말초혈액 자연살해세포의 측정이 반복유산 환자에서 다음 번 유산을 예측할 수 있는 유용한 지표임을 알 수 있다. Objectives: The purpose of this study was to compare the decidual NK cell populations between increased pre-conceptional peripheral NK cell population and normal pre-conceptional peripheral NK cell population in women with a history of recurrent abortion. Methods: Fourteen women with history of recurrent abortion and elevated pre-conceptional peripheral NK cell, above 15% of peripheral lymphocyte population were included in this study. As a control, twelve women with history of recurrent abortion and their peripheral NK cell percentage showed below 15% were included. Distribution of $CD56^+$ and $CD16^+$ NK cells in paraffin embedded decidual tissues including implantation sites were examined by immunohistochemical staining using anti-CD56, 16 monoclonal antibodies. After immuohistochemical staining, the numbers of decidual NK cells were counted and compared these results between study and control groups. Results: There was significant difference in decidual $CD56^+$ NK cell count ($170.1{\pm}132.1$ vs. $68.3{\pm}66.1$, p=0.02) between increased peripheral $CD56^+$ NK cell group and control group. But, there showed no statistically significant correlation between decidual $CD56^+$ NK cell count and peripheral $CD56^+$ NK cell percentage (r=0.229, p=0.261). Also there was no statistically difference decidual $CD16^+$ NK cell count between study and control group ($25.70{\pm}11.72$ vs. $31.17{\pm}22.67$), and no correlation between decidual $CD16^+$ NK cell and peripheral $CD16^+$ NK cell percentage (r=-1.40, p=0.535). Conclusions: This study shows that decidual $CD56^+$ NK cell are significantly increased in decidua of women exhibiting a history of recurrent abortion with increased $CD56^+$ peripheral NK cell. This study suggests that the percentage of peripheral NK cell reflect the expression of decidual NK cell. Consequently, pre-conceptional peripheral blood NK cell population can be the useful marker for detecting the risk of subsequent miscarriage.

      • KCI등재

        실험계획법을 이용한 동축 에어블로운 전기방사 공정의 최적화

        이현주,최민기,박진희,김주용,Lee, Hyun Joo,Choi, Min Ki,Park, Jin Hee,Kim, Jooyong 한국섬유공학회 2014 한국섬유공학회지 Vol.51 No.1

        In this study, a coaxial air-blown spinning system has been optimized for the variables of air flow rate, solution concentration, and voltage using the design of experiment (DOE) method. Both response surface analysis (RSA) and Taguchi's method (TM) were employed and compared to obtain the optimal process conditions. A total of 41 spinning trials were utilized and fitted with RSA and TM; they were then used to obtain mathematical prediction models. The resulting optimum parameters were an air flow rate of 20 l/min, a concentration of 8 wt%, and a voltage of 35 kV, predicting an average diameter of 335.76 nm with an estimated error of 18.85 nm. In TM, the SN ratio was calculated on randomly chosen data. The optimal process conditions that gave the largest SN ratio were an air flow rate of 20 l/min, a concentration of 8 wt%, and a voltage of 30 kV, representing the estimated SN ratio and diameter, -52.03 and 309.11 nm, respectively. For coaxial air-blown electrospinning under the same conditions, the experimental SN ratio and diameter were -52.0269 and 376.75 nm, respectively.

      • KCI등재후보

        난치성 녹내장에서 아메드 녹내장밸브 삽입술의 임상적 고찰

        이현주,최규룡,Hyun Joo Lee,Kyu Ryong Choi 대한안과학회 2006 대한안과학회지 Vol.47 No.6

        Purpose: To assess the efficacy, safety, and clinical outcome of the Ahmed glaucoma valve implant in refractory glaucoma. Methods: We retrospectively studied 55 eyes of 55 patients who underwent Ahmed glaucoma valve implantation for refractory glaucoma unresponsive to conventional management. The mean follow-up period was 26.3±11.5 months. Surgical success was defined as an intraocular pressure between 5 and 21 mmHg regardless of glaucoma medication. Results: The reduction of intraocular pressure was statistically significant (p<0.05) and the number of glaucoma medications was decreased. The 1-year and 2-year success rates were 83.0% and 75.8%, respectively. Complications included hyphema in 9 eyes, hypotony with shallow anterior chamber in 2 eyes, choroidal detachment in 4 eyes, tube obstruction in 1 eye, tube migration in 2 eyes, and bullous keratopathy in 2 eyes. Conclusions: Ahmed glaucoma valve implantation may provide good intraocular pressure control in patients with refractory glaucoma unresponsive to conventional treatments, and may be effective for reducing the incidence of hypotony in the early postoperative period.

      • KCI등재

        DRASTIC 모델 및 지하수 수치모사 연계 적용에 의한 부여읍 일대의 지하수 오염 취약성 평가

        이현주,박은규,김강주,박기훈,Lee, Hyun-Ju,Park, Eun-Gyu,Kim, Kang-Joo,Park, Ki-Hoon 한국지하수토양환경학회 2008 지하수토양환경 Vol.13 No.1

        본 연구에서는 지하수 오염 취약성 평가 방법 중 가장 활용도가 높은 DRASTIC 기법 및 지하수 수치모사 기법을 병행하여 충청남도 부여군 부여읍 일대의 지하수 오염 취약성 변화를 평가하였다. 특히, DRASTIC 기법에서 사용되는 7가지 수리인자들 중 취약성에 대한 민감도가 상대적으로 높고 비교적 장기간 자료의 획득이 용이하지 않은 '지하수위(depth to water)' 인자에 대하여 수치모사 기법을 적용하여 시-자료에 대한 동적 보간을 실시하였으며, 이를 통하여 시간에 따른 지하수위 변화가 지하수 오염 취약성에 미치는 영향을 검토하였다. 연구의 대상 지역은 부여군 부여읍 일대로 충적 대수층을 대상으로 기 실시된 지하수 수위자료를 보정대상으로 하였으며 연구지역의 지하수위 분포양상을 모사하기 위하여 유한차분모델인 MODFLOW를 이용하였다. 지하수 수치모사에는 정류 및 부정류 모사가 모두 실시되었다. 그 결과 기존 지구통계기법을 통한 지하수위 보간에서 가장 큰 가중치를 갖는 지형적 요인뿐만 아니라 유역 암상이나 지질특성 등과 같은 제반 수리지질학적 요인까지 복합적으로 반영하는 지하수위 자료를 얻을 수 있었다. 기존 연구에서 수위자료를 보완할 때 주로 이용되는 기법인 크리깅은 수치모사와는 달리 강우나 계절적 영향, 암상이나 지질등과 같은 요인들은 반영하지 못한다. 또한 수치모사를 통하여 얻어진 수위자료는 부정류 모사가 가능함으로 인하여 풍수기와 갈수기 그리고 평수기의 지하수위 변화 등도 파악할 수 있다는 장점이 있다. 모사를 통하여 얻어진 지하수위 자료와 공동크리깅 방법을 통해 얻어진 지하수위 자료를 입력자료로 하여 연구지역에 지하수 오염 취약성을 비교 평가한 결과 평수기의 경우 유사한 경향의 지하수 오염 취약성을 보였다. 또한 공동크리깅을 통해 분석이 어려운 분기별 지하수 오염 취약성 평가 결과 강우량이 많은 여름철을 포함한 분기와 강우량이 가장 적은 겨울철을 포함한 분기가 뚜렷한 취약성 차이를 보이는 것으로 분석되었다. 본 연구에서 제시하는 바와 같이 지하수 오염 취약성 평가에 있어 가장 큰 민감도를 갖는 수위자료의 수가 공간적 혹은 시간적으로 부족한 경우 수치모사 적용을 통해 자료의 한계성을 보완할 수 있으며 시간적인 보간이 이루어질 수 있어 유용할 수 있을 것이라 판단된다. In this study, we developed a technique of applying DRASTIC, which is the most widely used tool for estimation of groundwater vulnerability to the aqueous phase contaminant infiltrated from the surface, and a groundwater flow model jointly to assess groundwater contamination potential. The developed technique is then applied to Buyeo-eup area in Buyeo-gun, Chungcheongnam-do, Korea. The input thematic data of a depth to water required in DRASTIC model is known to be the most sensitive to the output while only a few observations at a few time schedules are generally available. To overcome this practical shortcoming, both steady-state and transient groundwater level distributions are simulated using a finite difference numerical model, MODFLOW. In the application for the assessment of groundwater vulnerability, it is found that the vulnerability results from the numerical simulation of a groundwater level is much more practical compared to cokriging methods. Those advantages are, first, the results from the simulation enable a practitioner to see the temporally comprehensive vulnerabilities. The second merit of the technique is that the method considers wide variety of engaging data such as field-observed hydrogeologic parameters as well as geographic relief. The depth to water generated through geostatistical methods in the conventional method is unable to incorporate temporally variable data, that is, the seasonal variation of a recharge rate. As a result, we found that the vulnerability out of both the geostatistical method and the steady-state groundwater flow simulation are in similar patterns. By applying the transient simulation results to DRASTIC model, we also found that the vulnerability shows sharp seasonal variation due to the change of groundwater recharge. The change of the vulnerability is found to be most peculiar during summer with the highest recharge rate and winter with the lowest. Our research indicates that numerical modeling can be a useful tool for temporal as well as spatial interpolation of the depth to water when the number of the observed data is inadequate for the vulnerability assessments through the conventional techniques.

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