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이현순,Lee, Hyeon-Sun 한국과학기술단체총연합회 1984 과학과 기술 Vol.17 No.12
이 논문은 한국과학기술단체총연합회 주최로 지난 11월23일 - 24일 2일간 열렸던 "바이오에너지와 에너지심포지움"에서 발표된 요지이다
당뇨 쥐에 대한 한약재복합추출물로 만든 현미율무밥의 혈당강하 효과
이현순 ( Hyeon Sun Lee ),공현주 ( Hyun Joo Kong ),이언희 ( Eon Hee Lee ),황수정 ( Su Jung Hwang ),정현아 ( Hyeon A Jung ),김미림 ( Mi Lim Kim ),최은미 ( Eun Mi Choi ),장정현 ( Joung Hyeon Jang ),양경미 ( Kyung Mi Yang ) 대한본초학회 2014 大韓本草學會誌 Vol.29 No.3
Objectives : The purpose of this study was to evaluate boiled rice made from unpolished rice, Job`s Tears, and extract from medicinal herbs mixture (HGMCJE) for hypoglycemic effect on STZ-induced diabetic rats. Methods : In the response of glucose tolerance, control and diabetic rats groups was intubated with glucose and HGMCJE. Furthermore, boiled 100% polished rice (P rice), boiled unpolished rice mixed with white rice and Job`s tears (polished rice:unpolished rice:Job`s tears=60:25:15, UPJ-rice), and UPJ rice made from HGMCJE (HUPJ-rice) were intubated to control and diabetic rats groups, respectively. Then, blood glucose concentration, incremental blood glucose, and area under the curve (ΔAUC) were analyzed in every experimental groups, and these data were used to evaluate glycemic response. Results : When glucose and p rice were intubated in control and diabetic rats, blood glucose concentration, incremental blood glucose, and incremental response ΔAUC of diabetic groups were significantly increase than control groups. But administraion of a single dose of extract from medicinal herbs mixture and HUPJ-rice in control and diabetic rats inhibited the remarkable increase the level of postprandial blood and ΔAUC at 60, 90, and 120 min Conclusions : These results indicate that when intubation of glucose and P rice were out of control on postprandial glycemic response in diabetic rats. But postprandial glycemic response was well-modulated by administrating a single oral dose of HGMCJE and HUPJ-rice. Therefore, HGMCJE can be developed as an effective hypoglycemic agent.