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이현국,이규언,김윤호,정재민,양한광,정준기,이건욱,최국진,Lee Hyeon Kook,Lee Kyu Eun,Kim Yoon Ho,Jeong Jae Min,Yang Han-Kwang,Chung June Key,Lee Kuhn Uk,Choe Kuk Jin 대한위암학회 2001 대한위암학회지 Vol.1 No.3
Purpose: For curative resection of recurrent gastric cancer, it is imperative that there be no unrecognized foci of tumoral disease outside the operation field. PET (positron emission tomography) with FDG (18 fluoro-2 deoxy-D-glucose) is a whole-body imaging technique that exploits the increased rate of glycolysis in tumor cells to detect disease. The authors evaluated the usefulness of FDG-PET in assessing resectability of recurrent gastric cancer. Materials and Methods: Seven patients with recurrent gastric cancer were studied with FDG-PET from December 1998 to October 2000. All FDG-PET images were interpreted in conjunction with conventional diagnostic methods. All imaging results were correlated with the pathological diagnosis and clinical outcome. Results: A final diagnosis of recurrence was obtained at 14 sites in all 7 patients by histology or clinical follow up. Locoregional recurrence, including distant metastasis, developed in 6 of 7 patients and distant recurrence in only one. FDG-PET detected all recurrent sites (5 locoregional and 5 distant) in 5 patients without peritoneal recurrence, but did not detect peritoneal seeding in 2 patients with peritoneal recurrence. The accuracy of FDG-PET in estimating resectability was $71.4\%$ (5/7), and that of CT and PET together was $85.7\%$ (6/7). A curative resection could be performed in three of the recurrent patients (2 locoregional and 1 distant recurrence). Conclusion: Our results suggest that FDG-PET may be useful for detecting locoregional and distant recurrence of gastric cancer and for selecting appropriate treatment. However, considering that FDG-PET was limited in detecting peritoneal seeding and determining the exact anatomical extension of tumor, it should be used in conjunction with other anatomical images.
이현국 ( Hyeon Gook Lee ),전국진 ( Kook Jin Chun ),이동완 ( Dong Wan Lee ),이혜정 ( Hye Jeong Lee ),김준홍 ( June Hong Kim ),홍택종 ( Taek Jong Hong ),신영우 ( Yung Woo Shin ) 대한내과학회 2005 대한내과학회지 Vol.69 No.-
저자들은 식사시작과 함께 심계항진을 주소로 내원한 63세 여자 환자에서 국내에서 아직 보고된 바 없는 연하 유발성 심방세동을 진단하였고, 약물치료로 호전되었기에 문헌고찰과 함께 보고하는 바이다. Deglutition tachyarrhythmias are rare. We report a case of atrial fibrillation triggered by swallowing. A 63 year old female presented to our hospital with a 20 day history of paroxysmal palpitations lasting approximately 5 to 10 seconds in duration and precipitated by ingestion of solids but not liquids. Cardiovascular examination, chest radiography, Echocardiography, upper GI endoscopy and thyroid function tests were normal and 24 hour ambulatory monitoring showed sinus rhythm except for numerous episodes of atrial fibrillation with rates of 150 to 200 beats/minute during meals. Most episodes spontaneously reverted to sinus rhythm within few minutes. The patient`s exercise tolerance was good with the achievement of 96% of the age predicted maximum heart rate. Her symptoms were controlled by verapamil. She is currently symptom-free with regular doses of verapamil under clinical follow-up. (Korean J Med 69:S818-S823, 2005)
이성철,이현국,양석진,정성은,박귀원,김우기,Lee, Seong-Cheol,Lee, Hyeon-Kook,Yang, Suk-Jin,Jung, Sung-Eun,Park, Kwi-Won,Kim, Woo-Ki 대한소아외과학회 1997 소아외과 Vol.3 No.1
Eight pediatric patients with Peutz-Jeghers syndrome were treated from 1984 to 1994 at the Department of Surgery, Seoul National University Children's Hospital. We reviewed the clinical features of our own 8 cases as well as 56 cases reported in Korean literatures. The results were compared to those of western reports. Gastrointestinal complications in our series were more frequent than in the Korean series, but the distribution of polyps was similar. The Korean series showed the following characteristics compared to the western reports; demographic backgrounds were similar; gastrointestinal symptoms were more common; location of the polyp was more frequent in colon (2 times); and the most prevalent site of malignant change was the colon in Korean cases.
습식 합성법에 의한 고순도 ${\alpha}-Al_2O_3$ 미세분말의 합성 연구
최진호,류종석,한양수,김준,이현국,김혁년,Jin-Ho Choy,Jong-Seok Yoo,Yang-Su Han,Joon Kim,Hyeon-Kook Lee,Hyuk-Nyun Kim 대한화학회 1991 대한화학회지 Vol.35 No.3
고순도 암모니움 명반 결정을 합성한 후 열분해 시켜 높은 순도의 초미세 산화알루미늄(${\alpha}-Al_2O_3$)분말을 합성하였다. 이 때 불순물인 Na$_2$O의 혼입과 Al(OH)$_3$의 침전을 최대한으로 방지하기 위해 pH = 1.5∼2.5의 영역에서 암모니움 명반을 합성하였으며, pH 조건은 수용액 중에서 Na와 Al 이온의 수산화물과 탄산염 형성을 고려, pH에 따른 각 이온종들의 농도가 이론적으로 계산되었다. 그 결과 ${\alpha}-Al_2O_3$의 순도는 99.7%이상이고, 입자는 ${\phi}$ = 0.1∼0.5 ${\mu}$m의 균일한 크기의 분말이 얻어졌다. Ultra-fine alumina, ${\alpha}-Al_2O_3$, with ${\phi}$ = 0.1∼0.5 ${\mu}$m was obtained from pure ammonium aluminum sulfate(alum) as the thermal decomposition product. Pure alum(> 99.7%) could be prepared by the precepitation and the successive recrystallization in an acidic aqueous solution at pH = 1.5∼2.5, which was theoretically predicted by only considering the concentrations of hydroxide and carbonate for aluminum and sodium in the solution, and also experimentally confirmed as the optimum precepitation condition for alum without forming any impurities like aluminum hydroxide or sodium one.
고혈압 환자에서 좌심실비대가 심실성 부정맥 발생에 미치는 영향
배우형(Woo Hyung Bae),이현국(Hyeon Gook Lee),박융인(Yoong In Park),박용현(Yong Hyun Park),오현명(Hyun Myung Oah),임종훈(Jong Hoon Lim),안병재(Byung Jae An),김성호(Seong Ho Kim),전국진(Kook Jin Chun),홍택종(Taek Jong Hong),신영우(Yung 대한내과학회 1999 대한내과학회지 Vol.56 No.4
N/A Objectives:Left ventricular hypertrophy(LVH) increases the risk of sudden death in hypertensive patients and this is known due to ventricular arrhythmias. Thus, author studied the relationship between LVH as a hypertensive target organ damage and ventricular arrhythmias. Methods:24-hour ambulatory electrocardiographic monitoring, measurement of microalbumin in 24-hour urine and fundoscopic examination were performed on 100 hypertensives (50 patients without LVH and 50 patients with LVH on EKG) who admitted Pusan National University Hospital. Results:In patients with LVH, ventricular extrasystoles occurred more frequently than without LVH(p<0.05) and ventricular couplet and ventricular tachycardia were more common but statistically not different. Microalbuminuria and hypertensive retinopathy were more severe in patients with LVH than without LVH(p<0.05 and p<0.01, respectively). Conclusion:Of the ventricular arrhythmias, ventricular extrasystole but not ventricular couplet and ventricular tachycardia occurred more frequently in patients with LVH than without LVH. Thus, prospective study with long-term follow up should be done to establish the relationship between hypertensive LVH and cardiovascular mortality, especially sudden death. And, further study should be done to make the relationship between reduction in LVH with antihypertensive therapy and reduction in LVH-associated ventricular arrhythmias.